Publications,References

Epigenetic Blockade of Hippocampal SOD2 Via DNMT3b-Mediated DNAMeth...
Published: October, 2020

Abstract: The recurrent events of mild trauma exacerbate the vulnerability for post-traumatic stress disorder; however, the underlying molecular mechanisms a... Read more »

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Antibody

p53 directly represses human LINE1 transposons.
Published: October, 2020

Abstract: p53 is a potent tumor suppressor and commonly mutated in human cancers. Recently, we demonstrated that p53 genes act to restrict retrotransposons i... Read more »

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Antibody

Radiation-induced H3K9 methylation on E-cadherin promoter mediated ...
Published: October, 2020

Abstract: Lung cancer patients who have undergone radiotherapy developed severe complications such as pneumonitis and fibrosis. Upon irradiation, epithelial ... Read more »

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iDeal ChIP-seq Kit for Histones

Formation of the CenH3-Deficient Holocentromere in Lepidoptera Avoi...
Published: October, 2020

Abstract: Despite the essentiality for faithful chromosome segregation, centromere architectures are diverse among eukaryotes and embody two main configurati... Read more »

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Antibody iDeal ChIP-seq Kit for Histones Beads

Network integration and modelling of dynamic drug responses at mult...
Published: October, 2020

Abstract: Uncovering cellular responses from heterogeneous genomic data is crucial for molecular medicine in particular for drug safety. This can be realized... Read more »

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MagMeDIP kit

Integrative Analysis of Glucometabolic Traits, Adipose Tissue DNA M...
Published: September, 2020

Abstract: Decline in insulin sensitivity due to dysfunction of adipose tissue (AT) is one of the earliest pathogenic events in Type 2 Diabetes. We hypothesiz... Read more »

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Premium RRBS Kit DNA Methylation Profiling (RRBS Service)

Genes with 5′ terminal oligopyrimidine tracts preferentially escape...
Published: September, 2020

Abstract: Viruses rely on the host translation machinery to synthesize their own proteins. Consequently, they have evolved varied mechanisms to co-opt host t... Read more »

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D-Plex small RNA-seq

Differential epigenetic regulation between the alternative promoter...
Published: September, 2020

Abstract: Multiple myeloma (MM) is a B-cell neoplasm that is characterized by the accumulation of malignant plasma cells in the bone marrow. The transcriptio... Read more »

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Premium Bisulfite Kit

Development of an ObLiGaRe Doxycycline Inducible Cas9 system for pr...
Published: September, 2020

Abstract: The CRISPR-Cas9 system has increased the speed and precision of genetic editing in cells and animals. However, model generation for drug developmen... Read more »

Circuit-specific hippocampal ΔFosB underlies resilience to stress-i...
Published: September, 2020

Abstract: Chronic stress is a key risk factor for mood disorders like depression, but the stress-induced changes in brain circuit function and gene expressio... Read more »

UTX/KDM6A suppresses AP-1 and a gliogenesis program during neuraldi...
Published: September, 2020

Abstract: BACKGROUND: UTX/KDM6A is known to interact and influence multiple different chromatin modifiers to promote an open chromatin environment to facilit... Read more »

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Antibody

Between-Generation Phenotypic and Epigenetic Stability in a Clonal ...
Published: September, 2020

Abstract: Epigenetic variation might play an important role in generating adaptive phenotypes by underpinning within-generation developmental plasticity, per... Read more »

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Antibody

RNF40 exerts stage-dependent functions in differentiating osteoblas...
Published: September, 2020

Abstract: The role of histone ubiquitination in directing cell lineage specification is only poorly understood. Our previous work indicated a role of the his... Read more »

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Microplex Library Preparation kit

Breakpoint mapping of a t(9;22;12) chronic myeloid leukaemia patien...
Published: September, 2020

Abstract: BACKGROUND: The genetic changes in chronic myeloid leukaemia (CML) have been well established, although challenges persist in cases with rare fusio... Read more »

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Megaruptor

Dual ARID1A/ARID1B loss leads to rapid carcinogenesis and disruptiv...
Published: September, 2020

Abstract: SWI/SNF chromatin remodelers play critical roles in development and cancer. The causal links between SWI/SNF complex disassembly and carcinogenesis... Read more »

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Antibody

Epigenetic regulation of the lineage specificity of primary human d...
Published: September, 2020

Abstract: Lymphatic and blood vascular endothelial cells (ECs) share several molecular and developmental features. However, these two cell types possess dist... Read more »

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IP-Star Compact Microplex Library Preparation kit iDeal ChIP-seq Kit for Histones Chromatin Profiling (ChIP-seq) Services

Epigenetic effects of low-level sodium arsenite exposure on human l...
Published: August, 2020

Abstract: Chronic exposure to inorganic arsenic is associated with a variety of adverse health effects, including lung, bladder, kidney, and liver cancer. Se... Read more »

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ChIP-seq

Frataxin gene editing rescues Friedreich's ataxia pathology in dors...
Published: August, 2020

Abstract: Friedreich's ataxia (FRDA) is an autosomal-recessive neurodegenerative and cardiac disorder which occurs when transcription of the FXN gene is sile... Read more »

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MagMeDIP kit Antibody

Combined treatment with CBP and BET inhibitors reverses inadvertent...
Published: August, 2020

Abstract: Diffuse intrinsic pontine gliomas (DIPG) are the most aggressive brain tumors in children with 5-year survival rates of only 2%. About 85% of all D... Read more »

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Bioruptor Antibody Microplex Library Preparation kit

Human papillomavirus type 38 alters wild-type p53 activity to promo...
Published: August, 2020

Abstract: Tumor suppressors can exert pro-proliferation functions in specific contexts. In the beta human papillomavirus type 38 (HPV38) experimental model, ... Read more »

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Chromatin Shearing IP-Star Compact iDeal ChIP-seq Kit for Histones

A gene therapy for inherited blindness using dCas9-VPR–mediatedtran...
Published: August, 2020

Abstract: Catalytically inactive dCas9 fused to transcriptional activators (dCas9-VPR) enables activation of silent genes. Many disease genes have counterpar... Read more »

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Antibody CRISPR

Differential Expression of Members of SOX Family of Transcription F...
Published: August, 2020

Abstract: Background: The Sry-related high-mobility-group box (SOX) gene family, with 20 known transcription factors in humans, plays essential roles during ... Read more »

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Antibody

Targeting DNA methylation depletes uterine leiomyoma stem-cell enri...
Published: August, 2020

Abstract: Uterine leiomyoma is the most common tumor in women and can cause severe morbidity. Leiomyoma growth requires maintenance and proliferation of a st... Read more »

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MethylCap

Integrated analysis of DNA methylation profile of HLA-G gene andima...
Published: August, 2020

Abstract: AIMS: Immune endothelial inflammation, underlying coronary heart disease (CHD) related phenotypes, could provide new insight into the pathobiology ... Read more »

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MagMeDIP kit

The transcription factor scleraxis differentially regulates gene ex...
Published: August, 2020

Abstract: The transcription factor scleraxis (SCX) is expressed throughout tendon development and plays a key role in directing tendon wound healing. However... Read more »

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Antibody iDeal ChIP-qPCR

DNA CpG methylation in sequential glioblastoma specimens.
Published: August, 2020

Abstract: PURPOSE: Glioblastoma is the most aggressive form of brain tumors. A better understanding of the molecular mechanisms leading to its evolution is e... Read more »

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Premium RRBS Kit

N-Methyladenosine co-transcriptionally directs the demethylation of...
Published: August, 2020

Abstract: A dynamic epigenome is critical for appropriate gene expression in development and health. Central to this is the intricate process of transcriptio... Read more »

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Bioruptor iDeal ChIP-seq Kit for Histones

Complete Genome Sequence of the Type Strain Pectobacterium punjaben...
Published: August, 2020

Abstract: Pectobacterium punjabense is a newly described species causing blackleg disease in potato plants. Therefore, by the combination of long (Oxford Nan... Read more »

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Megaruptor

Inhibition of the SET8 Pathway Ameliorates Lung Fibrosis Even Throu...
Published: August, 2020

Abstract: Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease of unknown etiopathogenesis. The activation of extracellular matrix (ECM)-producing myo... Read more »

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Antibody

Comparative DNA methylome analysis of estrus ewes reveals the compl...
Published: August, 2020

Abstract: BACKGROUND/AIMS: Sheep are important livestock with variant ovulation rate and fertility. Dorset sheep is a typical breed with low prolificacy, whe... Read more »

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MagMeDIP kit

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