Publications,References

The transcription factors Runx3 and ThPOK cross-regulate acquisitio...
Published: February, 2018

Abstract: Cytotoxic CD4 (CD4) T cells are emerging as an important component of antiviral and antitumor immunity, but the molecular basis of their developmen... Read more »

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Antibody

The CUE1 domain of the SNF2-like chromatin remodeler SMARCAD1 media...
Published: February, 2018

Abstract: Chromatin in embryonic stem cells (ESCs) differs markedly from that in somatic cells, with ESCs exhibiting a more open chromatin configuration. Acc... Read more »

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Antibody

Development of Real-time PCR Assays for the Detection of the pin II...
Published: February, 2018

Abstract: G-rich DNA sequences can form four-stranded G-quadruplex (G4) secondary structures and are linked to fundamental biological processes such as trans... Read more »

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Master Mix

TGFβ signaling hyperactivation-induced tumorigenicity during the de...
Published: February, 2018

Abstract: Clinical therapies of pluripotent stem cells (PSCs)-based transplantation have been hindered by frequent development of teratomas or tumors in anim... Read more »

Aberrant methylated key genes of methyl group metabolism within the...
Published: February, 2018

Abstract: Urothelial carcinoma (UC), the most common cancer of the urinary bladder causes severe morbidity and mortality, e.g. about 40.000 deaths in the EU ... Read more »

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MagMeDIP kit Antibody

A Non-catalytic Function of SETD1A Regulates Cyclin K and the DNA D...
Published: February, 2018

Abstract: MLL/SET methyltransferases catalyze methylation of histone 3 lysine 4 and play critical roles in development and cancer. We assessed MLL/SET protei... Read more »

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Antibody

Pro-inflammatory cytokine and high doses of ionizing radiation have...
Published: February, 2018

Abstract: The NF-κB transcription factors are activated via diverse molecular mechanisms in response to various types of stimuli. A plethora ... Read more »

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ChIP-seq

Ezh2 and Runx1 Mutations Collaborate to Initiate Lympho-Myeloid Leu...
Published: February, 2018

Abstract: Lympho-myeloid restricted early thymic progenitors (ETPs) are postulated to be the cell of origin for ETP leukemias, a therapy-resistant leukemia a... Read more »

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Antibody

Allele-Specific Chromatin Recruitment and Therapeutic Vulnerabiliti...
Published: February, 2018

Abstract: Estrogen receptor α (ER) ligand-binding domain (LBD) mutations are found in a substantial number of endocrine treatment-resistant metastatic ... Read more »

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Antibody

MAX to MYCN intracellular ratio drives the aggressive phenotype and...
Published: February, 2018

Abstract: Childhood neuroblastoma, a disease of the sympathetic nervous system, is the most common solid tumour of infancy, remarkably refractory to therapeu... Read more »

Micro-ribonucleic acid-155 is a direct target of Meis1, but not a d...
Published: February, 2018

Abstract: Micro-ribonucleic acid-155 (miR-155) is one of the first described oncogenic miRNAs. Although multiple direct targets of miR-155 have been identifi... Read more »

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Antibody

Inhibition of Methyltransferase Setd7 Allows the In Vitro Expansion...
Published: February, 2018

Abstract: The development of cell therapy for repairing damaged or diseased skeletal muscle has been hindered by the inability to significantly expand immatu... Read more »

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Antibody

Widespread bacterial protein histidine phosphorylation revealed by ...
Published: January, 2018

Abstract: For decades, major difficulties in analyzing histidine phosphorylation have limited the study of phosphohistidine signaling. Here we report a metho... Read more »

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Bioruptor Plus

Miz1 Controls Schwann Cell Proliferation via H3K36me2 Demethylase K...
Published: January, 2018

Abstract: Schwann cell differentiation and myelination depends on chromatin remodeling, histone acetylation, and methylation, which all affect Schwann cell p... Read more »

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Antibody

Targeted NUDT5 inhibitors block hormone signaling in breast cancer ...
Published: January, 2018

Abstract: With a diverse network of substrates, NUDIX hydrolases have emerged as a key family of nucleotide-metabolizing enzymes. NUDT5 (also called NUDIX5) ... Read more »

Genomic repeats, misassembly and reannotation: a case study with lo...
Published: January, 2018

Abstract: BACKGROUND: Without knowledge of their genomic sequences, it is impossible to make functional models of the bacteria that make up human and animal ... Read more »

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Megaruptor

The lncRNA GATA6-AS epigenetically regulates endothelial gene expre...
Published: January, 2018

Abstract: Impaired or excessive growth of endothelial cells contributes to several diseases. However, the functional involvement of regulatory long non-codin... Read more »

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Beads

A multi-omics study of the grapevine-downy mildew (Plasmopara vitic...
Published: January, 2018

Abstract: Fungicides are applied intensively to prevent downy mildew infections of grapevines (Vitis vinifera) with high impact on the environment. In order ... Read more »

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Microplex Library Preparation kit

Integrative omics data analyses of repeated dose toxicity of valpro...
Published: January, 2018

Abstract: Valproic acid (VPA) is a very potent anti-cancer and neuro-protective drug probably by its HDAC inhibiting properties, which may cause steatosis in... Read more »

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MagMeDIP kit

BCG Educates Hematopoietic Stem Cells to Generate Protective Innate...
Published: January, 2018

Abstract: The dogma that adaptive immunity is the only arm of the immune response with memory capacity has been recently challenged by several studies demons... Read more »

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Microplex Library Preparation kit

Metabolic Induction of Trained Immunity through the Mevalonate Path...
Published: January, 2018

Abstract: Innate immune cells can develop long-term memory after stimulation by microbial products during infections or vaccinations. Here, we report that me... Read more »

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Antibody

BCG Vaccination Protects against Experimental Viral Infection in Hu...
Published: January, 2018

Abstract: The tuberculosis vaccine bacillus Calmette-Guérin (BCG) has heterologous beneficial effects against non-related infections. The basis of the... Read more »

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Antibody

SIRT6-dependent cysteine monoubiquitination in the PRE-SET domain o...
Published: January, 2018

Abstract: Sirtuins are NAD+-dependent deacetylases that facilitate cellular stress response. They include SirT6, which protects genome stability and regulate... Read more »

A novel long noncoding RNA LINC00844 regulates prostate cancer cell...
Published: January, 2018

Abstract: The majority of the human genome is transcribed, yielding a rich repository of non-coding transcripts that are involved in a myriad of biological p... Read more »

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Bioruptor

Senescence-associated reprogramming promotes cancer stemness.
Published: January, 2018

Abstract: Cellular senescence is a stress-responsive cell-cycle arrest program that terminates the further expansion of (pre-)malignant cells. Key signalling... Read more »

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Antibody

APRDX1 mutant allele causes a MMACHC secondary epimutation in cblC ...
Published: January, 2018

Abstract: To date, epimutations reported in man have been somatic and erased in germlines. Here, we identify a cause of the autosomal recessive cblC class of... Read more »

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IP-Star Histone ChIP kit

Copper induces expression and methylation changes of early developm...
Published: January, 2018

Abstract: Copper contamination is widespread along coastal areas and exerts adverse effects on marine organisms such as mollusks. In the Pacific oyster, copp... Read more »

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MagMeDIP kit

STAT5BN642H is a driver mutation for T cell neoplasia
Published: January, 2018

Abstract: STAT5B is often mutated in hematopoietic malignancies. The most frequent STAT5B mutation, Asp642His (N642H), has been found in over 90 leukemia and... Read more »

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Antibody

Genome-wide analysis of day/night DNA methylation differences in Po...
Published: January, 2018

Abstract: DNA methylation is an important mechanism of epigenetic modification. Methylation changes during stress responses and developmental processes have ... Read more »

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MagMeDIP kit Antibody

Obligatory and facilitative allelic variation in the DNA methylome ...
Published: January, 2018

Abstract: Integrating epigenetic data with genome-wide association study (GWAS) results can reveal disease mechanisms. The genome sequence itself also&n... Read more »

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MagMeDIP kit Antibody

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