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Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Distinct epigenetic landscapes underlie the pathobiology of pancrea...
Published: May, 2018
Abstract: Recent studies have offered ample insight into genome-wide expression patterns to define pancreatic ductal adenocarcinoma (PDAC) subtypes, although... Read more »
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Antibody
Interplay of cell–cell contacts and RhoA/MRTF‐A signaling regulates...
Published: May, 2018
Abstract: Cell–cell and cell–matrix interactions guide organ development and homeostasis by controlling lineage specification and maintenance, bu... Read more »
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Bioruptor H3K4me3 (C15410003) Bioruptor Plus
Insulin promoter in human pancreatic β cells contacts diabetes susc...
Published: May, 2018
Abstract: Both type 1 and type 2 diabetes involve a complex interplay between genetic, epigenetic, and environmental factors. Our laboratory has been interes... Read more »
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IP-Star Compact Microplex Library Preparation kit True MicroChIP kit
Functional interplay between E2F7 and ribosomal rRNA gene transcrip...
Published: May, 2018
Abstract: A prerequisite for protein synthesis is the transcription of ribosomal rRNA genes by RNA polymerase I (Pol I), which controls ribosome biogenesis. ... Read more »
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Bioruptor
Local adaptation and ecological differentiation under selection, mi...
Published: May, 2018
Abstract: How the balance between selection, migration and drift influences the evolution of local adaptation has been under intense theoretical scrutiny. Ye... Read more »
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Bioruptor
The chromatin remodeling factor SPOC1 acts as a cellular restricti...
Published: May, 2018
Abstract: The cellular protein SPOC1 (survival time-associated PHD finger protein in ovarian cancer 1) acts as a regulator of chromatin structure and DNA dam... Read more »
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Bioruptor Bioruptor Plus
Modulation of gene transcription and epigenetics of colon carcinoma...
Published: May, 2018
Abstract: Interactions between bacteria and colon cancer cells influence the transcription of the host cell. Yet is it undetermined whether the bacteria itse... Read more »
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Microplex Library Preparation kit
Corticosteroid receptors adopt distinct cyclical transcriptional si...
Published: May, 2018
Abstract: Mineralocorticoid receptors (MRs) and glucocorticoid receptors (GRs) are two closely related hormone-activated transcription factors that regulate ... Read more »
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iDeal ChIP-seq Kit for Transcription Factors
Corticosteroid receptors adopt distinct cyclical transcriptional si...
Published: May, 2018
Abstract: Mineralocorticoid receptors (MRs) and glucocorticoid receptors (GRs) are two closely related hormone-activated transcription factors that regulate ... Read more »
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iDeal ChIP-seq Kit for Transcription Factors
Bcl11b, a novel GATA3-interacting protein, suppresses Th1 while lim...
Published: May, 2018
Abstract: GATA-binding protein 3 (GATA3) acts as the master transcription factor for type 2 T helper (Th2) cell differentiation and function. However, it is ... Read more »
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Antibody iDeal ChIP-seq Kit for Transcription Factors iDeal ChIP-seq Kit for Histones
A new metabolic gene signature in prostate cancer regulated by JMJD...
Published: May, 2018
Abstract: Histone methylation is essential for gene expression control. Trimethylated lysine 27 of histone 3 (H3K27me3) is controlled by the balance between ... Read more »
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Antibody IP-Star Compact True MicroChIP kit
Nuclear fate of yeast snoRNA is determined by co-transcriptional Rn...
Published: May, 2018
Abstract: Small nucleolar RNA (snoRNA) are conserved and essential non-coding RNA that are transcribed by RNA Polymerase II (Pol II). Two snoRNA classes, for... Read more »
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Bioruptor
The Ftx Noncoding Locus Controls X Chromosome Inactivation Independ...
Published: May, 2018
Abstract: Accumulation of the Xist long noncoding RNA (lncRNA) on one X chromosome is the trigger for X chromosome inactivation (XCI) in female mammals.... Read more »
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Antibody
Retinoid-Sensitive Epigenetic Regulation of the Hoxb Cluster Mainta...
Published: May, 2018
Abstract: Hox genes modulate the properties of hematopoietic stem cells (HSCs) and reacquired Hox expression in progenitors contributes to leukemogenesis. He... Read more »
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True MicroChIP kit
SUN2 Modulates HIV-1 Infection and Latency through Association with...
Published: May, 2018
Abstract: The postintegrational latency of HIV-1 is characterized by reversible silencing of long terminal repeat (LTR)-driven transcription of the HIV gen... Read more »
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Bioruptor
The novel BET bromodomain inhibitor BI 894999 represses super-enhan...
Published: May, 2018
Abstract: Bromodomain and extra-terminal (BET) protein inhibitors have been reported as treatment options for acute myeloid leukemia (AML) in preclinical mod... Read more »
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Antibody
Viral targeting of TFIIB impairs de novo polymerase II recruitment ...
Published: April, 2018
Abstract: Viruses have evolved a plethora of mechanisms to target host antiviral responses. Here, we propose a yet uncharacterized mechanism of immune regula... Read more »
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Bioruptor Bioruptor Plus
HMGB2 Loss upon Senescence Entry Disrupts Genomic Organization and ...
Published: April, 2018
Abstract: Processes like cellular senescence are characterized by complex events giving rise to heterogeneous cell populations. However, the early molecular ... Read more »
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Bioruptor Bioruptor Plus
Combined cistrome and transcriptome analysis of SKI in AML cells id...
Published: April, 2018
Abstract: SKI is a transcriptional co-regulator and overexpressed in various human tumors, for example in acute myeloid leukemia (AML). SKI contributes to th... Read more »
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Microplex Library Preparation kit
Generation of a PAX6 knockout glioblastoma cell line with changes i...
Published: April, 2018
Abstract: The transcription factor PAX6 is expressed in various cancers. In anaplastic astrocytic glioma, PAX6 expression is inversely related to tumor gra... Read more »
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Bioruptor Bioruptor Plus
MYCN acts as a direct co-regulator of p53 in MYCN amplified neurobl...
Published: April, 2018
Abstract: The MYC oncogenes and p53 have opposing yet interrelated roles in normal development and tumorigenesis. How MYCN expression alters the biology and ... Read more »
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Bioruptor
T Cell Receptor-Regulated TGF-β Type I Receptor Expression Determin...
Published: April, 2018
Abstract: It is unclear how quiescence is enforced in naive T cells, but activation by foreign antigens and self-antigens is allowed, despite the presen... Read more »
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HighCell ChIP kit
spe-43 is required for sperm activation in C. elegans.
Published: April, 2018
Abstract: Successful fertilization requires that sperm are activated prior to contacting an oocyte. In C. elegans, this activation process, called spermiogen... Read more »
A long range distal enhancer controls temporal fine-tuning of PAX6 ...
Published: April, 2018
Abstract: Proper embryonic development relies on a tight control of spatial and temporal gene expression profiles in a highly regulated manner. One good exam... Read more »
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Antibody Microplex Library Preparation kit
Pro-inflammatory cytokines activate hypoxia-inducible factor 3α via...
Published: April, 2018
Abstract: Human mesenchymal stromal/stem cells (hMSCs) emerged as a promising therapeutic tool for ischemic disorders, due to their ability to regenerate dam... Read more »
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Antibody
HDAC1 and HDAC2 Modulate TGF-β Signaling during Endothelial-to-Hema...
Published: April, 2018
Abstract: The first hematopoietic stem and progenitor cells are generated during development from hemogenic endothelium (HE) through trans-differentiation. T... Read more »
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HighCell ChIP kit Microplex Library Preparation kit
Contrasting epigenetic states of heterochromatin in the different t...
Published: April, 2018
Abstract: Mouse embryonic stem cells (ESCs) and epiblast stem cells (EpiSCs) represent naive and primed pluripotency states, respectively, and are maintained... Read more »
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True MicroChIP kit
Meg3 Non-coding RNA Expression Controls Imprinting by Preventing Tr...
Published: April, 2018
Abstract: Although many long non-coding RNAs (lncRNAs) are imprinted, their roles often remain unknown. The Dlk1-Dio3 domain expresses the lncRNA Meg3 and mu... Read more »
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Antibody
Molecular Signatures of Regression of the Canine Transmissible Vene...
Published: April, 2018
Abstract: The canine transmissible venereal tumor (CTVT) is a clonally transmissible cancer that regresses spontaneously or after treatment with vincristine,... Read more »
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MagMeDIP kit Antibody IP-Star Compact
Structural and mechanistic insights into UHRF1-mediated DNMT1 activ...
Published: April, 2018
Abstract: UHRF1 plays multiple roles in regulating DNMT1-mediated DNA methylation maintenance during DNA replication. The UHRF1 C-terminal RING finger functi... Read more »
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Antibody

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