Publications,References

Differential α-synuclein expression contributes to selective vulner...
Published: March, 2018

Abstract: The accumulation of misfolded α-synuclein (aSyn) and neuron loss define several neurodegenerative disorders including Parkinson’s disea... Read more »

Lyar-mediated recruitment of Brd2 to the chromatin attenuates Nanog...
Published: March, 2018

Abstract: During development, cellular differentiation programs need of tight regulation for proper display of the activity of multiple factors in time and s... Read more »

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Bioruptor

Epigenetic modifiers promote mitochondrial biogenesis and oxidative...
Published: March, 2018

Abstract: During neural development, epigenetic modulation of chromatin acetylation is part of a dynamic, sequential and critical process to steer the fate o... Read more »

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Antibody iDeal ChIP-seq Kit for Histones

Epigenome analysis links gene regulatory elements in group 2 innate...
Published: March, 2018

Abstract: BACKGROUND: Group 2 innate lymphoid cells (ILC2s) are major producers of the cytokines driving allergic asthma, and increased ILC2 numbers have bee... Read more »

Copper induces expression and methylation changes of early developm...
Published: March, 2018

Abstract: Copper contamination is widespread along coastal areas and exerts adverse effects on marine organisms such as mollusks. In the Pacific oyster, copp... Read more »

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MagMeDIP kit Antibody

Genome-wide analysis of PDX1 target genes in human pancreatic proge...
Published: March, 2018

Abstract: OBJECTIVE: Homozygous loss-of-function mutations in the gene coding for the homeobox transcription factor (TF) PDX1 leads to pancreatic agenesis, w... Read more »

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Antibody Microplex Library Preparation kit

Selenite and methylseleninic acid epigenetically affects distinct g...
Published: March, 2018

Abstract: Selenium compounds have emerged as promising chemotherapeutic agents with proposed epigenetic effects, however the mechanisms and downstream effect... Read more »

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iDeal ChIP-seq Kit for Histones

The Transcriptionally Permissive Chromatin State of Embryonic Stem ...
Published: March, 2018

Abstract: A permissive chromatin environment coupled to hypertranscription drives the rapid proliferation of embryonic stem cells (ESCs) and peri-implantatio... Read more »

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LowCell ChIP kit

PRDM9 Methyltransferase Activity Is Essential for Meiotic DNA Doubl...
Published: March, 2018

Abstract: The programmed formation of hundreds of DNA double-strand breaks (DSBs) is essential for proper meiosis and fertility. In mice and humans, the loca... Read more »

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Antibody

Long noncoding RNA LISPR1 is required for S1P signaling and endothe...
Published: March, 2018

Abstract: Sphingosine-1-Phosphate (S1P) is a potent signaling lipid. The effects of S1P are mediated by the five S1P receptors (S1PR). In the endothelium S1P... Read more »

The transcription factors Runx3 and ThPOK cross-regulate acquisitio...
Published: February, 2018

Abstract: Cytotoxic CD4 (CD4CTX) T cells are emerging as an important component of antiviral and antitumor immunity, but the molecular basis of their develop... Read more »

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H3pan (C15310135)

β1-integrin impacts Rad51 stability and DNA double-strand break rep...
Published: February, 2018

Abstract: The molecular mechanisms underlying resistance to radiotherapy in breast cancer cells remain elusive. Previously, we reported that elevated &beta... Read more »

The transcription factors Runx3 and ThPOK cross-regulate acquisitio...
Published: February, 2018

Abstract: Cytotoxic CD4 (CD4) T cells are emerging as an important component of antiviral and antitumor immunity, but the molecular basis of their developmen... Read more »

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Antibody

The CUE1 domain of the SNF2-like chromatin remodeler SMARCAD1 media...
Published: February, 2018

Abstract: Chromatin in embryonic stem cells (ESCs) differs markedly from that in somatic cells, with ESCs exhibiting a more open chromatin configuration. Acc... Read more »

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Antibody

Development of Real-time PCR Assays for the Detection of the pin II...
Published: February, 2018

Abstract: G-rich DNA sequences can form four-stranded G-quadruplex (G4) secondary structures and are linked to fundamental biological processes such as trans... Read more »

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Master Mix

TGFβ signaling hyperactivation-induced tumorigenicity during the de...
Published: February, 2018

Abstract: Clinical therapies of pluripotent stem cells (PSCs)-based transplantation have been hindered by frequent development of teratomas or tumors in anim... Read more »

Aberrant methylated key genes of methyl group metabolism within the...
Published: February, 2018

Abstract: Urothelial carcinoma (UC), the most common cancer of the urinary bladder causes severe morbidity and mortality, e.g. about 40.000 deaths in the EU ... Read more »

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MagMeDIP kit Antibody

A Non-catalytic Function of SETD1A Regulates Cyclin K and the DNA D...
Published: February, 2018

Abstract: MLL/SET methyltransferases catalyze methylation of histone 3 lysine 4 and play critical roles in development and cancer. We assessed MLL/SET protei... Read more »

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Antibody

Pro-inflammatory cytokine and high doses of ionizing radiation have...
Published: February, 2018

Abstract: The NF-κB transcription factors are activated via diverse molecular mechanisms in response to various types of stimuli. A plethora ... Read more »

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ChIP-seq

Ezh2 and Runx1 Mutations Collaborate to Initiate Lympho-Myeloid Leu...
Published: February, 2018

Abstract: Lympho-myeloid restricted early thymic progenitors (ETPs) are postulated to be the cell of origin for ETP leukemias, a therapy-resistant leukemia a... Read more »

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Antibody

Allele-Specific Chromatin Recruitment and Therapeutic Vulnerabiliti...
Published: February, 2018

Abstract: Estrogen receptor α (ER) ligand-binding domain (LBD) mutations are found in a substantial number of endocrine treatment-resistant metastatic ... Read more »

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Antibody

MAX to MYCN intracellular ratio drives the aggressive phenotype and...
Published: February, 2018

Abstract: Childhood neuroblastoma, a disease of the sympathetic nervous system, is the most common solid tumour of infancy, remarkably refractory to therapeu... Read more »

Micro-ribonucleic acid-155 is a direct target of Meis1, but not a d...
Published: February, 2018

Abstract: Micro-ribonucleic acid-155 (miR-155) is one of the first described oncogenic miRNAs. Although multiple direct targets of miR-155 have been identifi... Read more »

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Antibody

Inhibition of Methyltransferase Setd7 Allows the In Vitro Expansion...
Published: February, 2018

Abstract: The development of cell therapy for repairing damaged or diseased skeletal muscle has been hindered by the inability to significantly expand immatu... Read more »

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Antibody

Widespread bacterial protein histidine phosphorylation revealed by ...
Published: January, 2018

Abstract: For decades, major difficulties in analyzing histidine phosphorylation have limited the study of phosphohistidine signaling. Here we report a metho... Read more »

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Bioruptor Plus

Miz1 Controls Schwann Cell Proliferation via H3K36me2 Demethylase K...
Published: January, 2018

Abstract: Schwann cell differentiation and myelination depends on chromatin remodeling, histone acetylation, and methylation, which all affect Schwann cell p... Read more »

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Antibody

Targeted NUDT5 inhibitors block hormone signaling in breast cancer ...
Published: January, 2018

Abstract: With a diverse network of substrates, NUDIX hydrolases have emerged as a key family of nucleotide-metabolizing enzymes. NUDT5 (also called NUDIX5) ... Read more »

Genomic repeats, misassembly and reannotation: a case study with lo...
Published: January, 2018

Abstract: BACKGROUND: Without knowledge of their genomic sequences, it is impossible to make functional models of the bacteria that make up human and animal ... Read more »

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Megaruptor

The lncRNA GATA6-AS epigenetically regulates endothelial gene expre...
Published: January, 2018

Abstract: Impaired or excessive growth of endothelial cells contributes to several diseases. However, the functional involvement of regulatory long non-codin... Read more »

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Beads

A multi-omics study of the grapevine-downy mildew (Plasmopara vitic...
Published: January, 2018

Abstract: Fungicides are applied intensively to prevent downy mildew infections of grapevines (Vitis vinifera) with high impact on the environment. In order ... Read more »

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Microplex Library Preparation kit

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