Publications,References

TET2 binds the androgen receptor and loss is associated with prosta...
Published: November, 2016

Abstract: Genetic alterations associated with prostate cancer (PCa) may be identified by sequencing metastatic tumour genomes to identify molecular markers a... Read more »

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Antibody

A set of novel automated quantitative microproteomics protocols for...
Published: November, 2016

Abstract: Here we assessed the ability of an automated sample preparation device equipped with disposable microcolumns to prepare mass-limited samples for hi... Read more »

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Bioruptor Mass Spectrometry

Transcriptional Activation of Pericentromeric Satellite Repeats and...
Published: November, 2016

Abstract: Heterochromatinisation of pericentromeres, which in mice consist of arrays of major satellite repeats, are important for centromere formation and m... Read more »

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Bioruptor IPure kit

Chromatin Preparation and Chromatin Immuno-precipitation from Droso...
Published: November, 2016

Abstract: This protocol provides specific details on how to perform Chromatin immunoprecipitation (ChIP) from Drosophila embryos. ChIP allows the matching of... Read more »

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Antibody

Iterative Fragmentation Improves the Detection of ChIP-seq Peaks fo...
Published: October, 2016

Abstract: As chromatin immunoprecipitation (ChIP) sequencing is becoming the dominant technique for studying chromatin modifications, new protocols surface t... Read more »

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Bioruptor Antibody

Genetic variation at the 8q24.21 renal cancer susceptibility locus ...
Published: October, 2016

Abstract: Clear cell renal cell carcinoma (ccRCC) is characterized by loss of function of the von Hippel-Lindau tumour suppressor (VHL) and unrestrained acti... Read more »

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Bioruptor Antibody

DNA methylation and alcohol use disorders: Progress and challenges
Published: October, 2016

Abstract: Background and Objectives Risk for alcohol use disorders (AUDs) is influenced by gene–environment interactions. Environmental factors can ... Read more »

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Premium RRBS Kit

Analysis of Cohesin Function in Gene Regulation and Chromatin Organ...
Published: October, 2016

Abstract: Cohesin is essential for the maintenance of chromosomes through the cell cycle. In addition, cohesin contributes to the regulation of gene expressi... Read more »

Foxo3 Transcription Factor Drives Pathogenic T Helper 1 Differentia...
Published: October, 2016

Abstract: The transcription factor Foxo3 plays a crucial role in myeloid cell function but its role in lymphoid cells remains poorly defined. Here, we have s... Read more »

Chronic stress leads to epigenetic dysregulation in the neuropeptid...
Published: October, 2016

Abstract: Persistent stress triggers a variety of mechanisms, which may ultimately lead to the occurrence of anxiety- and depression-related disorders. Epige... Read more »

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Antibody

Regulation of transcriptional elongation in pluripotency and cell d...
Published: October, 2016

Abstract: Pluripotent embryonic stem cells (ESCs) self-renew or differentiate into all tissues of the developing embryo and cell-specification factors are ne... Read more »

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Antibody

In vivo conditional deletion of HDAC7 reveals its requirement to es...
Published: October, 2016

Abstract: Class IIa histone deacetylase (HDAC) subfamily members are tissue-specific gene repressors with crucial roles in development and differentiation pr... Read more »

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LowCell ChIP kit True MicroChIP kit

Zeb2 Regulates Cell Fate at the Exit from Epiblast State in Mouse E...
Published: October, 2016

Abstract: In human ESCs the transcription factor Zeb2 regulates neuroectoderm versus mesendoderm formation, but it is unclear how Zeb2 affects the global tra... Read more »

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Premium RRBS Kit

DNA fragmentation and quality control analysis
Published: September, 2016

Abstract: Optimal data generation using NGS platforms relies on a few sample-preparation prerequisites, namely, precise DNA fragmentation, size-range an... Read more »

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DNA shearing Bioruptor

The lncRNA landscape of breast cancer reveals a role for DSCAM-AS1 ...
Published: September, 2016

Abstract: Molecular classification of cancers into subtypes has resulted in an advance in our understanding of tumour biology and treatment response across m... Read more »

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HighCell ChIP kit IPure kit

Novel regional age-associated DNA methylation changes within human ...
Published: September, 2016

Abstract: BACKGROUND: Advancing age progressively impacts on risk and severity of chronic disease. It also modifies the epigenome, with changes in DNA met... Read more »

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MagMeDIP kit 5mC (C15200081)

Deficient expression of JMJD1A histone demethylase in patients with...
Published: September, 2016

Abstract: JMJD1A (jumonji domain-containing 1A), a known histone H3K9 demethylase, has been identified as a critical epigenetic regulator in male germ cells,... Read more »

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Histone ChIP kit

Inheritable Silencing of Endogenous Genes by Hit-and-Run Targeted E...
Published: September, 2016

Abstract: Gene silencing is instrumental to interrogate gene function and holds promise for therapeutic applications. Here, we repurpose the endogenous retro... Read more »

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Bioruptor MagMeDIP kit IPure kit

Trichloroethylene-Induced DNA Methylation Changes in Male F344 Rat ...
Published: September, 2016

Abstract: Trichloroethylene (TCE), a common environmental contaminant, causes hepatocellular carcinoma in mice but not in rats. To understand the mechanisms ... Read more »

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MagMeDIP kit

Neonatal monocytes exhibit a unique histone modification landscape
Published: September, 2016

Abstract: Background Neonates have dampened expression of pro-inflammatory cytokines and difficulty clearing pathogens. This makes them uniquely susceptib... Read more »

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Antibody

BRD4 localization to lineage-specific enhancers is associated with ...
Published: September, 2016

Abstract: Proper temporal epigenetic regulation of gene expression is essential for cell fate determination and tissue development. The Bromodomain-containin... Read more »

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Antibody Microplex Library Preparation kit

Coordinate redeployment of PRC1 proteins suppresses tumor formation...
Published: September, 2016

Abstract: Polycomb group proteins form two main complexes, PRC2 and PRC1, which generally coregulate their target genes. Here we show that PRC1 components ac... Read more »

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Antibody

Overexpression of histone demethylase Fbxl10 leads to enhanced migr...
Published: September, 2016

Abstract: Cell migration is a central process in the development and maintenance of multicellular organisms. Tissue formation during embryonic development, w... Read more »

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Antibody

CTCF modulates Estrogen Receptor function through specific chromati...
Published: September, 2016

Abstract: Enhancer regions and transcription start sites of estrogen-target regulated genes are connected by means of Estrogen Receptor long-range chromatin ... Read more »

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Microplex Library Preparation kit

Heterochromatic histone modifications at transposons in Xenopus tro...
Published: September, 2016

Abstract: Transposable elements are parasitic genomic elements that can be deleterious for host gene function and genome integrity. Heterochromatic histone m... Read more »

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Antibody

Allelic reprogramming of the histone modification H3K4me3 in early ...
Published: September, 2016

Abstract: Histone modifications are fundamental epigenetic regulators that control many crucial cellular processes1. However, whether these marks can be pass... Read more »

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Antibody

Detection of Protein-Protein Interactions and Posttranslational Mod...
Published: September, 2016

Abstract: The detection of protein-protein interactions by imaging techniques often requires the overexpression of the proteins of interest tagged with fluor... Read more »

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Antibody

Condition-dependent co-regulation of genomic clusters of virulence ...
Published: September, 2016

Abstract: The ascomycete Neofusicoccum parvum, one of the causal agents of Botryosphaeria dieback, is a destructive wood-infecting fungus and a serious threa... Read more »

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Megaruptor

Esrrb directly binds to Gata6 promoter and regulates its expression...
Published: September, 2016

Abstract: Estrogen-related receptor beta (Esrrb) is expressed in embryonic stem (ES) cells and is involved in self-renewal ability and pluripotency. Previous... Read more »

Evolutionary Consequences of DNA Methylation in a Basal Metazoan.
Published: September, 2016

Abstract: Gene body methylation (gbM) is an ancestral and widespread feature in Eukarya, yet its adaptive value and evolutionary implications remain unresolv... Read more »

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MethylCap

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