Publications,References

PaperClip: rapid multi-part DNA assembly from existing libraries.
Published: September, 2014

Abstract: Assembly of DNA 'parts' to create larger constructs is an essential enabling technique for bioengineering and synthetic biology. Here we describe a... Read more »

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Bioruptor Cell Lysis

Chromatin immunoprecipitation for human monocyte derived macrophages.
Published: September, 2014

Abstract: The importance of Chromatin Immunoprecipitation (ChIP) technology has grown exponentially along with an increased interest in epigenetic regulation... Read more »

Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis t...
Published: September, 2014

Abstract: Wilms tumour is the most common childhood kidney cancer. Here we report the whole-exome sequencing of 44 Wilms tumours, identifying missense mutati... Read more »

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Bioruptor Cell Lysis

The pro-apoptotic activity of Drosophila Rbf1 involves dE2F2-depend...
Published: September, 2014

Abstract: The retinoblastoma gene, rb, ensures at least its tumor suppressor function by inhibiting cell proliferation. Its role in apoptosis is more complex... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR IPure kit

Identification of a Face Enhancer Reveals Direct Regulation of LIM ...
Published: September, 2014

Abstract: Development of the mammalian face requires a large number of genes that are expressed with spatio-temporal specificity, and transcriptional regulat... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Histone methyltransferase MMSET/NSD2 alters EZH2 binding and reprog...
Published: September, 2014

Abstract: Overexpression of the histone methyltransferase MMSET in t(4;14)+ multiple myeloma patients is believed to be the driving factor in the pathogenesi... Read more »

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Bioruptor

Histone-fold domain protein NF-Y promotes chromatin accessibility f...
Published: September, 2014

Abstract: Cell type-specific master transcription factors (TFs) play vital roles in defining cell identity and function. However, the roles ubiquitous factor... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Cell Lysis Western Blot

Determinants of G quadruplex-induced epigenetic instability in REV1...
Published: September, 2014

Abstract: REV1-deficient chicken DT40 cells are compromised in replicating G quadruplex (G4)-forming DNA. This results in localised, stochastic loss of paren... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Pcgf6, a polycomb group protein, regulates mesodermal lineage diffe...
Published: September, 2014

Abstract: Polycomb group (PcG) proteins comprise evolutionary conserved factors with essential functions for embryonic development and adult stem cells. PcG ... Read more »

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Antibody

Pregnane X receptor activation and silencing promote steatosis of h...
Published: September, 2014

Abstract: In addition to its well-characterized role in the regulation of drug metabolism and transport by xenobiotics, pregnane X receptor (PXR) critically ... Read more »

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Bioruptor Cell Lysis

A dynamic CTCF chromatin binding landscape promotes DNA hydroxymeth...
Published: September, 2014

Abstract: CCCTC-binding factor (CTCF) is a ubiquitously expressed multifunctional transcription factor characterized by chromatin binding patterns often desc... Read more »

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Bioruptor Cell Lysis

Mechanism-based genotoxicity screening of metal oxide nanoparticles...
Published: September, 2014

Abstract: BACKGROUND: The rapid expansion of manufacturing and use of nano-sized materials fuels the demand for fast and reliable assays to identify their po... Read more »

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Bioruptor

Genome-wide distribution of Auts2 binding localizes with active neu...
Published: September, 2014

Abstract: The autism susceptibility candidate 2 gene (AUTS2) has been associated with multiple neurological diseases including autism spectrum disorders (ASD... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Highly conserved ENY2/Sus1 protein binds to Drosophila CTCF and is ...
Published: September, 2014

Abstract: Chromatin insulators affect interactions between promoters and enhancers/silencers and function as barriers for the spreading of repressive chromat... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

A thermo-halo-tolerant and proteinase-resistant endoxylanase from B...
Published: September, 2014

Abstract: A glycosyl hydrolase family 10 endoxylanase from Bacillus sp. HJ14 was grouped in a separated cluster with another six Bacillus endoxylanases which... Read more »

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DNA shearing Bioruptor

Nanog induces hyperplasia without initiating tumors.
Published: September, 2014

Abstract: Though expression of the homeobox transcription factor Nanog is generally restricted to pluripotent cells and early germ cells, many contradictory ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Chromatin enrichment for proteomics.
Published: September, 2014

Abstract: During interphase, chromatin hosts fundamental cellular processes, such as gene expression, DNA replication and DNA damage repair. To analyze chrom... Read more »

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Bioruptor Chromatin Shearing

Early lineage restriction in temporally distinct populations of Mes...
Published: September, 2014

Abstract: Cardiac development arises from two sources of mesoderm progenitors, the first heart field (FHF) and the second (SHF). Mesp1 has been proposed to m... Read more »

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Bioruptor Chromatin Shearing ChIP-seq IPure kit

Interrogation of allelic chromatin states in human cells by high-de...
Published: September, 2014

Abstract: Allele-specific (AS) assessment of chromatin has the potential to elucidate specific cis-regulatory mechanisms, which are predicted to underlie the... Read more »

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Antibody H3K4me3 (C15410003)

The cytokine TGF-β co-opts signaling via STAT3-STAT4 to promote the...
Published: September, 2014

Abstract: Understanding the developmental mechanisms of follicular helper T cells (TFH cells) in humans is relevant to the clinic. However, the factors that ... Read more »

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Antibody

Microevolution of Burkholderia pseudomallei during an acute infection.
Published: September, 2014

Abstract: We used whole-genome sequencing to evaluate 69 independent colonies of Burkholderia pseudomallei isolated from seven body sites of a patient with a... Read more »

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Megaruptor

Hypomethylated pollen bypasses the interploidy hybridization barrie...
Published: September, 2014

Abstract: Plants of different ploidy levels are separated by a strong postzygotic hybridization barrier that is established in the endosperm. Deregulated par... Read more »

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DNA shearing Bioruptor Bioruptor Plus

Transgenic analysis of the Leishmania MAP kinase MPK10 reveals an a...
Published: September, 2014

Abstract: Protozoan pathogens of the genus Leishmania have evolved unique signaling mechanisms that can sense changes in the host environment and trigger ada... Read more »

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Bioruptor Cell Lysis

Dopamine signaling leads to loss of polycomb repression and aberran...
Published: September, 2014

Abstract: Polycomb group (PcG) proteins bind to and repress genes in embryonic stem cells through lineage commitment to the terminal differentiated state. Pc... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR ChIP-seq

Y chromosomes of 40% Chinese descend from three Neolithic super-gra...
Published: August, 2014

Abstract: Demographic change of human populations is one of the central questions for delving into the past of human beings. To identify major population exp... Read more »

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DNA shearing Bioruptor

oxBS-450K: A method for analysing hydroxymethylation using 450K Bea...
Published: August, 2014

Abstract: DNA methylation analysis has become an integral part of biomedical research. For high-throughput applications such as epigenome-wide association st... Read more »

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DNA shearing Bioruptor

BDNF Epigenetic Modifications Associated with Schizophrenia-Like Ph...
Published: August, 2014

Abstract: Background Prenatal stress is considered a risk factor for several neurodevelopmental disorders including schizophrenia (SZ). An animal model invo... Read more »

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MeDIP kit

Differences among brain tumor stem cell types and fetal neural stem...
Published: August, 2014

Abstract: BACKGROUND: Aberrational epigenetic marks are believed to play a major role in establishing the abnormal features of cancer cells. Rational use and... Read more »

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DNA shearing Bioruptor Chromatin Shearing Antibody H3K4me3 (C15410003)

Mediator can regulate mitotic entry and direct periodic transcripti...
Published: August, 2014

Abstract: Cdk8 is required for correct timing of mitotic progression in fission yeast. How the activity of Cdk8 is regulated is unclear, since the kinase is ... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Histone methylation has distinct dynamics from histone acetylation ...
Published: August, 2014

Abstract: Cell growth is attuned to nutrient availability to sustain homeostatic biosynthetic processes. In unfavorable environments, cells enter a non-proli... Read more »

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Bioruptor Chromatin Shearing Cell Lysis ChIP-seq Western Blot

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