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Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Transmission from centenarians to their offspring of mtDNA heteropl...
Published: May, 2014
Abstract: The role that mtDNA heteroplasmy plays in healthy aging, familial longevity and the heritability patterns of low levels heteroplasmy in the elderly... Read more »
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DNA shearing Bioruptor
IL-15 regulates Bcl-2 family members Bim and Mcl-1 through JAK/STAT...
Published: May, 2014
Abstract: Maintenance of T cells is determined by their survival capacity, which is regulated by Bcl-2 proteins. Cytokines signalling through the common gamm... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
Promyelocytic Leukaemia Zinc Finger Retinoic Acid Receptor α (PLZF-...
Published: May, 2014
Abstract: PLZF-RARα is an oncogene transcriptional repressor that is generated by a chromosomal translocation between the PLZF and RARα genes in acute promye... Read more »
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MeDIP kit
The LIM domain protein nTRIP6 recruits the mediator complex to AP-1...
Published: May, 2014
Abstract: Several LIM domain proteins regulate transcription. They are thought to act through their LIM protein-protein interaction domains as adaptors for t... Read more »
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Antibody
Genomic analysis of the emergence of 20th century epidemic dysentery.
Published: May, 2014
Abstract: BACKGROUND: Shigella dysenteriae type 1 (Sd1) causes recurrent epidemics of dysentery associated with high mortality in many regions of the world. ... Read more »
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DNA shearing Bioruptor
The Transcriptional Regulators TAZ and YAP Direct Transforming Grow...
Published: May, 2014
Abstract: Uncontrolled transforming growth factor-β (TGFβ) signaling promotes aggressive metastatic properties in late-stage breast cancers. However, how TGF... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Insights into how Spt5 functions in transcription elongation and re...
Published: May, 2014
Abstract: Spt5, a transcription elongation factor, and Rpb4, a subunit of RNA polymerase II (RNAP II) that forms a subcomplex with Rpb7, play important roles... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Sleep Fragmentation During Late Gestation Induces Metabolic Perturb...
Published: May, 2014
Abstract: Sleep fragmentation (SF) is a common condition among pregnant women, particularly during late gestation. Gestational perturbations promote the emer... Read more »
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Antibody
Identification of regulators of the three-dimensional polycomb orga...
Published: May, 2014
Abstract: Polycomb group (PcG) proteins dynamically define cellular identities through epigenetic repression of key developmental genes. PcG target gene repr... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Nitric oxide-induced neuronal to glial lineage fate-change depends ...
Published: May, 2014
Abstract: Degeneration of CNS tissue commonly occurs during neuroinflammatory conditions, such as multiple sclerosis (MS) and neurotrauma. During such condit... Read more »
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Antibody H3K27me3 (C15410069) H3K27ac (C15410174) H3pan (C15310135)
Dendritic cell development requires histone deacetylase activity.
Published: May, 2014
Abstract: DCs develop from multipotent progenitors (MPPs), which commit into DC-restricted common dendritic cell progenitors (CDPs). CDPs further differentia... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody
The extent of error-prone replication-restart by homologous recombi...
Published: May, 2014
Abstract: Genetic instability, a hallmark of cancer, can occur when the replication machinery encounters a barrier. The intra-S phase checkpoint maintains st... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Biogeography and phylogenomics of New World Bambusoideae (Poaceae),...
Published: May, 2014
Abstract: • Premise of the study: New World Bambusoideae have only recently been studied in a phylogenomic context. Plastome sequences were determined and an... Read more »
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DNA shearing Bioruptor
Myostatin Regulates Energy Homeostasis in the Heart and Prevents He...
Published: May, 2014
Abstract: RATIONALE: Myostatin is a major negative regulator of skeletal muscle mass and initiates multiple metabolic changes including enhanced insulin sens... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody
Fetal programming of adult Leydig cell function by androgenic effec...
Published: May, 2014
Abstract: Fetal growth plays a role in programming of adult cardiometabolic disorders, which in men, are associated with lowered testosterone levels. Fetal g... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Enriched domain detector: a program for detection of wide genomic e...
Published: May, 2014
Abstract: Nuclear lamins contact the genome at the nuclear periphery through large domains and are involved in chromatin organization. Among broad peak calli... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
EXPRSS: an Illumina based high-throughput expression-profiling meth...
Published: May, 2014
Abstract: BACKGROUND: Next Generation Sequencing technologies have facilitated differential gene expression analysis through RNA-seq and Tag-seq methods. RNA... Read more »
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DNA shearing Bioruptor
Thyroid hormone induction of human cholesterol 7 alpha-hydroxylase ...
Published: May, 2014
Abstract: Thyroid hormone (TH) modulates serum cholesterol by acting on TH receptor β1 (TRβ1) in liver to regulate metabolic gene sets. In rodents, one impor... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Highly efficient differentiation of embryonic stem cells into adipo...
Published: May, 2014
Abstract: Adipocyte differentiation and function have become the major research targets due to the increasing interest in obesity and related metabolic condi... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
MIR146A inhibits JMJD3 expression and osteogenic differentiation in...
Published: May, 2014
Abstract: Chromatin remodeling is important for cell differentiation. Histone methyltransferase EZH2 and histone demethylase JMJD3 (KDM6B) modulate levels of... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
Reassessment of QTLs for Late Blight Resistance in the Tomato Acces...
Published: May, 2014
Abstract: omato late blight caused by the oomycete pathogen Phytophthora infestans (Mont.) de Bary is a major threat to tomato production in cool and wet env... Read more »
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DNA shearing Bioruptor
The plant metacaspase AtMC1 in pathogen-triggered programmed cell d...
Published: May, 2014
Abstract: Autophagy is a major nutrient recycling mechanism in plants. However, its functional connection with programmed cell death (PCD) is a topic of acti... Read more »
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Bioruptor Cell Lysis
Trrap-dependent histone acetylation specifically regulates cell-cyc...
Published: May, 2014
Abstract: Fate decisions in neural progenitor cells are orchestrated via multiple pathways, and the role of histone acetylation in these decisions has been a... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody LowCell ChIP kit Bioruptor Plus
DNA hypermethylation in prostate cancer is a consequence of aberran...
Published: May, 2014
Abstract: Prostate cancer (CaP) is mostly composed of luminal-like differentiated cells, but contains a small subpopulation of basal cells (including stem-li... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The Ah Receptor Recruits IKKα to Its Target Binding Motifs to Phosp...
Published: May, 2014
Abstract: Aryl hydrocarbon receptor (AHR) activation by xenobiotic ligands such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is key to their toxicity. Follo... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Repression of the Proapoptotic Cellular BIK/NBK Gene by Epstein-Bar...
Published: May, 2014
Abstract: UNLABELLED: The Epstein-Barr virus (EBV) establishes a lifelong latent infection in humans. EBV infection of primary B cells causes cell activation... Read more »
Early-life stress reduces DNA methylation of the pomc gene in male ...
Published: May, 2014
Abstract: Early-life stress (ELS) increases the vulnerability thresholds for stress-related diseases such as major depression and anxiety by inducing alterat... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Estrogen receptor ligands ameliorate fatty liver through a nonclass...
Published: May, 2014
Abstract: UNLABELLED: Liver X receptor (LXR) activation stimulates triglyceride (TG) accumulation in the liver. Several lines of evidence indicate that estra... Read more »
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Antibody
The myc 3' wnt-responsive element suppresses colonic tumorigenesis.
Published: May, 2014
Abstract: Mutations in components of the Wnt/β-catenin signaling pathway are commonly found in colorectal cancers, and these mutations cause aberrant express... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Function-based identification of mammalian enhancers using site-spe...
Published: May, 2014
Abstract: The accurate and comprehensive identification of functional regulatory sequences in mammalian genomes remains a major challenge. Here we describe s... Read more »
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DNA shearing Bioruptor

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