Publications,References

Epigenetics meets genetics in acute myeloid leukemia: clinical impa...
Published: February, 2014

Abstract: PURPOSE: Molecular risk stratification of acute myeloid leukemia (AML) is largely based on genetic markers. However, epigenetic changes, including ... Read more »

Geriatric muscle stem cells switch reversible quiescence into senes...
Published: February, 2014

Abstract: Regeneration of skeletal muscle depends on a population of adult stem cells (satellite cells) that remain quiescent throughout life. Satellite cell... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR LowCell ChIP kit

Runx1t1 (Runt-related transcription factor 1; translocated to, 1) e...
Published: February, 2014

Abstract: BACKGROUND: Microglia, the resident immune cells of the brain, undergo rapid proliferation and produce several proinflammatory molecules and nitric... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Glial wingless/Wnt regulates glutamate receptor clustering and syna...
Published: February, 2014

Abstract: Glial cells are emerging as important regulators of synapse formation, maturation, and plasticity through the release of secreted signaling molecul... Read more »

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Bioruptor Chromatin Shearing

The long non-coding RNA Paupar regulates the expression of both loc...
Published: February, 2014

Abstract: Although some long noncoding RNAs (lncRNAs) have been shown to regulate gene expression in cis, it remains unclear whether lncRNAs can directly reg... Read more »

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DNA shearing Bioruptor

Genome-wide binding patterns of thyroid hormone receptor beta.
Published: February, 2014

Abstract: Thyroid hormone (TH) receptors (TRs) play central roles in metabolism and are major targets for pharmaceutical intervention. Presently, however, th... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Long-term parental methamphetamine exposure of mice influences beha...
Published: February, 2014

Abstract: The high rate of methamphetamine (METH) abuse among young adults and women of childbearing age makes it imperative to determine the long-term effec... Read more »

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DNA shearing Bioruptor Antibody 5mC (C15200081)

CDK phosphorylation of SLD-2 is required for replication initiation...
Published: February, 2014

Abstract: Cyclin-dependent kinase (CDK) plays a vital role in proliferation control across eukaryotes. Despite this, how CDK mediates cell cycle and developm... Read more »

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Bioruptor Cell Lysis Western Blot

Reduced Euchromatin histone methyltransferase 1 causes developmenta...
Published: February, 2014

Abstract: Haploinsufficiency of Euchromatin histone methyltransferase 1 (EHMT1), a chromatin modifying enzyme, is the cause of Kleefstra syndrome (KS). KS is... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Sp1 and Sp3 transcription factors regulate the basal expression of ...
Published: February, 2014

Abstract: Microsomal epoxide hydrolase (mEH, EPHX1) is a critical biotransformation enzyme, catalyzing the metabolism of many xenobiotics. Human mEH is trans... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

C/EBPα poises B cells for rapid reprogramming into induced pluripot...
Published: February, 2014

Abstract: CCAAT/enhancer binding protein-α (C/EBPα) induces transdifferentiation of B cells into macrophages at high efficiencies and enhances reprogramming ... Read more »

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DNA shearing Bioruptor

Nonstochastic reprogramming from a privileged somatic cell state.
Published: February, 2014

Abstract: Reprogramming somatic cells to induced pluripotency by Yamanaka factors is usually slow and inefficient and is thought to be a stochastic process. ... Read more »

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DNA shearing Bioruptor

BayMeth: Improved DNA methylation quantification for affinity captu...
Published: February, 2014

Abstract: DNA methylation (DNAme) is a critical component of the epigenetic regulatory machinery and aberrations in DNAme patterns occur in many diseases, su... Read more »

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MethylCap

A deterministic analysis of genome integrity during neoplastic grow...
Published: February, 2014

Abstract: The development of cancer has been associated with the gradual acquisition of genetic alterations leading to a progressive increase in malignancy. ... Read more »

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DNA shearing Bioruptor Bioruptor Plus

Sumoylation of the THO complex regulates the biogenesis of a subset...
Published: February, 2014

Abstract: Assembly of messenger ribonucleoparticles (mRNPs) is a pivotal step in gene expression, but only a few molecular mechanisms contributing to its reg... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

c-Myc-dependent transcriptional regulation of cell cycle and nucleo...
Published: February, 2014

Abstract: Oligodendrocyte progenitor cells (OPCs) have the ability to divide or to growth arrest and differentiate into myelinating oligodendrocytes in the d... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Hundreds of circular novel plasmids and DNA elements identified in ...
Published: February, 2014

Abstract: Metagenomic approaches are widespread in microbiological research, but so far, the knowledge on extrachromosomal DNA diversity and composition has ... Read more »

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DNA shearing Bioruptor

A Drosophila in vivo screen identifies store-operated calcium entry...
Published: February, 2014

Abstract: To unravel the evolutionarily conserved genetic network underlying energy homeostasis, we performed a systematic in vivo gene knockdown screen in D... Read more »

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Bioruptor Tissue Homogenization

A novel microscopy-based high-throughput screening method to identi...
Published: February, 2014

Abstract: Posttranslational modifications of histones play an important role in the regulation of gene expression and chromatin structure in eukaryotes. The ... Read more »

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Antibody

A high-throughput method for GMO multi-detection using a microfluid...
Published: February, 2014

Abstract: The ever-increasing production of genetically modified crops generates a demand for high-throughput DNA-based methods for the enforcement of geneti... Read more »

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Master Mix

Distribution, recognition and regulation of non-CpG methylation in ...
Published: February, 2014

Abstract: DNA methylation has critical roles in the nervous system and has been traditionally considered to be restricted to CpG dinucleotides in metazoan ge... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus

Hypoxia perturbs aryl hydrocarbon receptor signaling and CYP1A1 exp...
Published: February, 2014

Abstract: The aryl hydrocarbon receptor (AhR) is an important mediator of toxic responses after exposure to xenobiotics including 2,3,7,8-tetrachlorodibenzo-... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Adult glucocorticoid exposure leads to transcriptional and DNA meth...
Published: February, 2014

Abstract: Synthetic glucocorticoids (sGCs) are commonly prescribed for the management of inflammatory and endocrine disorders. However, nothing is known rega... Read more »

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DNA shearing Bioruptor

The BAF60 Subunit of the SWI/SNF Chromatin-Remodeling Complex Direc...
Published: February, 2014

Abstract: SWI/SNF complexes mediate ATP-dependent chromatin remodeling to regulate gene expression. Many components of these complexes are evolutionarily con... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR IPure kit

DSSylation, a novel protein modification targets proteins induced b...
Published: February, 2014

Abstract: Timely removal of oxidatively damaged proteins is critical for cells exposed to oxidative stresses; however, cellular mechanism for clearing oxidiz... Read more »

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Bioruptor Cell Lysis

A cohesin-independent role for NIPBL at promoters provides insights...
Published: February, 2014

Abstract: The cohesin complex is crucial for chromosome segregation during mitosis and has recently also been implicated in transcriptional regulation and ch... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

The role of plasma membrane estrogen receptors in mediating the est...
Published: February, 2014

Abstract: Progesterone is well known for its role in the modulation of sexual behavior. In the ventromedial nucleus (VMN), a part of the mediobasal hypothala... Read more »

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Bioruptor Western Blot Tissue Homogenization

Human RECQ5 helicase promotes repair of DNA double-strand breaks by...
Published: February, 2014

Abstract: Most mitotic homologous recombination (HR) events proceed via a synthesis-dependent strand annealing mechanism to avoid crossing over, which may gi... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Role of plasma membrane estrogen receptors in mediating the estroge...
Published: February, 2014

Abstract: Progesterone is well known for its role in the modulation of sexual behavior. In the ventromedial nucleus (VMN), a part of the mediobasal hypothala... Read more »

The chromatin remodeller CHD8 is required for E2F-dependent transcr...
Published: February, 2014

Abstract: The precise regulation of S-phase-specific genes is critical for cell proliferation. How the repressive chromatin configuration mediated by the ret... Read more »

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Bioruptor Chromatin Shearing

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