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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

A highly conserved region within H2B is important for FACT to act o...
Published: February, 2014
Abstract: Histone N-terminal tails play crucial roles in chromatin-related processes. The tails of histones H3 and H4 are highly conserved and well character... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The Mef2 transcription network is disrupted in myotonic dystrophy h...
Published: January, 2014
Abstract: Cardiac dysfunction is the second leading cause of death in myotonic dystrophy type 1 (DM1), primarily because of arrhythmias and cardiac conductio... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Assembly of the genome of the disease vector Aedes aegypti onto a g...
Published: January, 2014
Abstract: The mosquito Aedes aegypti transmits some of the most important human arboviruses, including dengue, yellow fever and chikungunya viruses. It has a... Read more »
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DNA shearing Bioruptor
ZFHX4 interacts with the NuRD core member CHD4 and regulates the gl...
Published: January, 2014
Abstract: Glioblastoma (GBM) harbors subpopulations of therapy-resistant tumor-initiating cells (TICs) that are self-renewing and multipotent. To understand ... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Simvastatin impairs growth hormone-activated signal transducer and ...
Published: January, 2014
Abstract: Recent studies have demonstrated that statins reduce cell viability and induce apoptosis in various types of cancer cells. The molecular mechanisms... Read more »
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Master Mix
Inhibition of HDAC1 and DNMT1 modulate RGS10 expression and decreas...
Published: January, 2014
Abstract: RGS10 is an important regulator of cell survival and chemoresistance in ovarian cancer. We recently showed that RGS10 transcript expression is supp... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The role of DNA methylation in regulation of the murine Lhx3 gene.
Published: January, 2014
Abstract: LHX3 is a LIM-homeodomain transcription factor with critical roles in pituitary and nervous system development. Mutations in the LHX3 gene are asso... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
A role for peroxisome proliferator-activated receptor γ coactivator...
Published: January, 2014
Abstract: The energy demands of the adult mammalian heart are met largely by ATP generated via oxidation of fatty acids in a high capacity mitochondrial syst... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Interactions between JARID2 and noncoding RNAs regulate PRC2 recrui...
Published: January, 2014
Abstract: JARID2 is an accessory component of Polycomb repressive complex-2 (PRC2) required for the differentiation of embryonic stem cells (ESCs). A role fo... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
An Easy, Convenient Cell and Tissue Extraction Protocol for Nuclear...
Published: January, 2014
Abstract: INTRODUCTION: As a complement to the classic metabolomics biofluid studies, the visualisation of the metabolites contained in cells or tissues coul... Read more »
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Bioruptor Cell Lysis
Suppression of UV-B stress responses by flg22 is regulated at the c...
Published: January, 2014
Abstract: Genes of the flavonol pathway are activated by UV-B, but suppressed by concomitant flg22 application in Arabidopsis. Analysis at the metabolite lev... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Lysine-specific demethylase 1 regulates differentiation onset and m...
Published: January, 2014
Abstract: Propagation and differentiation of stem cell populations are tightly regulated to provide sufficient cell numbers for tissue formation while mainta... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody
Lysine deacetylase inhibition prevents diabetes by chromatin-indepe...
Published: January, 2014
Abstract: Type 1 diabetes is due to destruction of pancreatic β-cells. Lysine deacetylase inhibitors (KDACi) protect β-cells from inflammatory destruction in... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Structural basis for the inhibition of the chromatin repressor BAHD...
Published: January, 2014
Abstract: UNLABELLED: The nucleus has emerged as a key target for nucleomodulins, a family of effectors produced by bacterial pathogens to control host trans... Read more »
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Bioruptor Chromatin Shearing
Increased binding of MeCP2 to the GAD1 and RELN promoters may be me...
Published: January, 2014
Abstract: Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by symptoms related to altered social interactions/communication and ... Read more »
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Antibody
SUPT6H controls estrogen receptor activity and cellular differentia...
Published: January, 2014
Abstract: The estrogen receptor alpha (ERα) is the central transcriptional regulator of ductal mammary epithelial lineage specification and is an important p... Read more »
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Antibody H3K27me3 (C15410069)
Hsp70 cochaperones HspBP1 and BAG-1M differentially regulate steroi...
Published: January, 2014
Abstract: Hsp70 binding protein 1 (HspBP1) and Bcl2-associated athanogene 1 (BAG-1), the functional orthologous nucleotide exchange factors of the heat shock... Read more »
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Bioruptor
Do ABO blood group antigens hamper the therapeutic efficacy of mese...
Published: January, 2014
Abstract: Investigation into predictors for treatment outcome is essential to improve the clinical efficacy of therapeutic multipotent mesenchymal stromal ce... Read more »
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MagMeDIP kit
Alterations of epigenetic signatures in hepatocyte nuclear factor 4...
Published: January, 2014
Abstract: Hepatocyte nuclear factor 4α (HNF4α) is a liver-enriched transcription factor essential for liver development and function. In hepatocytes, HNF4α r... Read more »
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Antibody 5mC (C15200081)
Peroxisome proliferator-activated receptor γ regulates genes involv...
Published: January, 2014
Abstract: The nuclear receptor peroxisome proliferator-activated receptor (PPAR) is a transcription factor whose expression is induced during adipogenesis an... Read more »
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DNA shearing Bioruptor Antibody 5mC (C15200081)
LIM homeobox 8 (Lhx8) is a key regulator of the cholinergic neurona...
Published: January, 2014
Abstract: Basal forebrain cholinergic neurons play an important role in cognitive functions such as learning and memory, and they are affected in several neu... Read more »
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LowCell ChIP kit
SPBP is a sulforaphane induced transcriptional coactivator of NRF2 ...
Published: January, 2014
Abstract: Organisms exposed to oxidative stress respond by orchestrating a stress response to prevent further damage. Intracellular levels of antioxidant age... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Pan-histone demethylase inhibitors simultaneously targeting Jumonji...
Published: January, 2014
Abstract: In prostate cancer, two different types of histone lysine demethylases (KDM), LSD1/KDM1 and JMJD2/KDM4, are coexpressed and colocalize with the and... Read more »
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Antibody H3K4me3 (C15410003)
Quiescent hepatic stellate cells functionally contribute to the hep...
Published: January, 2014
Abstract: Toll-like Receptor 3 (TLR3) is a pathogen pattern recognition receptor that plays a key role in innate immunity. TLR3 signalling has numerous funct... Read more »
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Antibody
Depletion of sirtuin 1 (SIRT1) leads to epigenetic modifications of...
Published: January, 2014
Abstract: Sirtuin 1 (SIRT1) is a nicotinamide adenine dinucleotide (NAD)-dependent deacetylase that is implicated in plethora of biological processes, includ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
mRNA levels of related Abcb genes change opposite to each other upo...
Published: January, 2014
Abstract: The multidrug-resistant phenotype of tumor cells is acquired via an increased capability of drug efflux by ABC transporters and causes serious prob... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
DUSP1 is a novel target for enhancing pancreatic cancer cell sensit...
Published: January, 2014
Abstract: Pancreatic ductal adenocarcinoma (PDAC) is a deadly cancer with a poor prognosis that is characterized by excessive mitogenic pathway activation an... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The thyroid hormone receptor β induces DNA damage and premature sen...
Published: January, 2014
Abstract: There is increasing evidence that the thyroid hormone (TH) receptors (THRs) can play a role in aging, cancer and degenerative diseases. In this pap... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
A role for FACT in repopulation of nucleosomes at inducible genes.
Published: January, 2014
Abstract: Xenobiotic drugs induce Pleiotropic Drug Resistance (PDR) genes via the orthologous Pdr1/Pdr3 transcription activators. We previously identified th... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Mutations in POGLUT1, encoding protein O-glucosyltransferase 1, cau...
Published: January, 2014
Abstract: Dowling-Degos disease (DDD) is an autosomal-dominant genodermatosis characterized by progressive and disfiguring reticulate hyperpigmentation. We p... Read more »
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DNA shearing Bioruptor

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