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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

HMGA1 recruits CTIP2-repressed P-TEFb to the HIV-1 and cellular tar...
Published: April, 2014
Abstract: Active positive transcription elongation factor b (P-TEFb) is essential for cellular and human immunodeficiency virus type 1 (HIV-1) transcription ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Anp32e, a higher eukaryotic histone chaperone directs preferential ...
Published: April, 2014
Abstract: H2A.Z is a highly conserved histone variant in all species. The chromatin deposition of H2A.Z is specifically catalyzed by the yeast chromatin remo... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Global effects of the CSR-1 RNA interference pathway on the transcr...
Published: April, 2014
Abstract: Argonaute proteins and their small RNA cofactors short interfering RNAs are known to inhibit gene expression at the transcriptional and post-transc... Read more »
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Antibody H3K27me3 (C15410195)
A novel protein, CHRONO, functions as a core component of the mamma...
Published: April, 2014
Abstract: Circadian rhythms are controlled by a system of negative and positive genetic feedback loops composed of clock genes. Although many genes have been... Read more »
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Chromatin Shearing ChIP-seq
High-throughput sequencing exclusively identified a novel Torque te...
Published: April, 2014
Abstract: Torque teno virus (TTV) has been found to be prevalent world-wide in healthy populations and in patients with various diseases, but its etiological... Read more »
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DNA shearing Bioruptor
MBD4 cooperates with DNMT1 to mediate methyl-DNA repression and pro...
Published: April, 2014
Abstract: Oxidative stress induces genome-wide remodeling of the chromatin structure. In this study, we identify Methyl-CpG Binding Protein 4 (MBD4), a multi... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR IP-Star
Rad51-Rad52 mediated maintenance of centromeric chromatin in Candid...
Published: April, 2014
Abstract: Specification of the centromere location in most eukaryotes is not solely dependent on the DNA sequence. However, the non-genetic determinants of c... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
TAp73 is essential for germ cell adhesion and maturation in testis.
Published: March, 2014
Abstract: A core evolutionary function of the p53 family is to protect the genomic integrity of gametes. However, the role of p73 in the male germ line is un... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Persistent STAT5 activation in myeloid neoplasms recruits p53 into ...
Published: March, 2014
Abstract: STAT (Signal Transducer and Activator of Transcription) transcription factors are constitutively activated in most hematopoietic cancers. We previo... Read more »
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Antibody
High-resolution chromatin immunoprecipitation (ChIP) sequencing rev...
Published: March, 2014
Abstract: Sex determining region Y-box 11 (SOX11) expression is specific for mantle cell lymphoma (MCL) as compared with other non-Hodgkin's lymphomas. Howev... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Overexpressed homeobox B9 regulates oncogenic activities by transfo...
Published: March, 2014
Abstract: Glioma is the leading cause of deaths related to tumors in the central nervous system. The mechanisms of gliomagenesis remain elusive to date. Home... Read more »
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Antibody
Subtelomeric CTCF and cohesin binding site organization using impro...
Published: March, 2014
Abstract: Mapping genome-wide data to human subtelomeres has been problematic due to the incomplete assembly and challenges of low-copy repetitive DNA elemen... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Frequent mutations in chromatin-remodelling genes in pulmonary carc...
Published: March, 2014
Abstract: Pulmonary carcinoids are rare neuroendocrine tumours of the lung. The molecular alterations underlying the pathogenesis of these tumours have not b... Read more »
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DNA shearing Bioruptor
Disturbed subsurface microbial communities follow equivalent trajec...
Published: March, 2014
Abstract: Microbial community structure, and niche and neutral processes can all influence response to disturbance. Here, we provide experimental evidence fo... Read more »
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DNA shearing Bioruptor
Modelling mutational landscapes of human cancers in vitro.
Published: March, 2014
Abstract: Experimental models that recapitulate mutational landscapes of human cancers are needed to decipher the rapidly expanding data on human somatic mut... Read more »
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DNA shearing Bioruptor
Inter-laboratory Testing of GMO Detection by Combinatory SYBR®Green...
Published: March, 2014
Abstract: Combinatory SYBR®Green real-time PCR Screening (CoSYPS) is an efficient, sensitive approach for detecting complex targets such as genetically modif... Read more »
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Master Mix
High-throughput quantitative proteomic analysis of dengue virus typ...
Published: March, 2014
Abstract: Disease caused by dengue virus is a global health concern with up to 390 million individuals infected annually worldwide. There are no vaccines or ... Read more »
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Bioruptor
Hic-5 influences genomic and non-genomic actions of the androgen re...
Published: March, 2014
Abstract: There is extensive knowledge of androgen receptor (AR) signaling in cancer cells, but less regarding androgen action in stromal cells of the tumor ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
GABA and glutamate pathways are spatially and developmentally affec...
Published: March, 2014
Abstract: Proper brain functioning requires a fine-tuning between excitatory and inhibitory neurotransmission, a balance maintained through the regulation an... Read more »
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Bioruptor Western Blot Tissue Homogenization
Calcineurin/NFAT signaling represses genes Vamp1 and Vamp2 via PMCA...
Published: March, 2014
Abstract: BACKGROUND: Plasma membrane Ca(2+)-ATPases (PMCA) extrude Ca(2+) ions out of the cell and contribute to generation of calcium oscillations. Calcium... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Identification of protein partners in mycobacteria using a single-s...
Published: March, 2014
Abstract: Tuberculosis is a leading cause of death in developing countries. Efforts are being made to both prevent its spread and improve curability rates. U... Read more »
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Bioruptor Cell Lysis
Hmga2 is required for canonical WNT signaling during lung development.
Published: March, 2014
Abstract: BACKGROUND: The high-mobility-group (HMG) proteins are the most abundant non-histone chromatin-associated proteins. HMG proteins are present at hig... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Stem Cells Protect the Bronchial Stump in Rat, Increasing Sox6, Col...
Published: March, 2014
Abstract: BACKGROUND: Post-pneumonectomy bronchopleural fistulas (BPFs) are associated with high morbidity and mortality. Currently, since the management of ... Read more »
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Master Mix
Large-scale analysis of tandem repeat variability in the human genome.
Published: March, 2014
Abstract: Tandem repeats are short DNA sequences that are repeated head-to-tail with a propensity to be variable. They constitute a significant proportion of... Read more »
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DNA shearing Bioruptor
Integrative ChIP-seq/microarray analysis identifies a CTNNB1 target...
Published: March, 2014
Abstract: BACKGROUND: Deregulation of canonical Wnt/CTNNB1 (beta-catenin) pathway is one of the earliest events in the pathogenesis of colon cancer. Mutation... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
An increase in MECP2 dosage impairs neural tube formation.
Published: March, 2014
Abstract: Epigenetic mechanisms are fundamental for shaping the activity of the central nervous system (CNS). Methyl-CpG binding protein 2 (MECP2) acts as a ... Read more »
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Antibody
Calcium-sensing receptor silencing in colorectal cancer is associat...
Published: March, 2014
Abstract: The calcium-sensing receptor (CaSR) is suggested to mediate the antiproliferative effects of calcium in colon. However, in colorectal cancer (CRC) ... Read more »
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Antibody
PI3K-p110-alpha-subtype signalling mediates survival, proliferation...
Published: March, 2014
Abstract: Development of the cerebral cortex is controlled by growth factors among which transforming growth factor beta (TGFβ) and insulin-like growth facto... Read more »
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Bioruptor Cell Lysis
Fine mapping of genome activation in bovine embryos by RNA sequencing.
Published: March, 2014
Abstract: During maternal-to-embryonic transition control of embryonic development gradually switches from maternal RNAs and proteins stored in the oocyte to... Read more »
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DNA shearing Bioruptor
Synthesis of multifunctional lipid–polymer conjugates: application ...
Published: March, 2014
Abstract: A new class of lipid-ended polymer conjugates presenting reactive sites regularly distributed along the polymer chain were synthesized using RAFT p... Read more »
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Bioruptor Liposome Preparation Bioruptor Plus

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