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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Histone deacetylase inhibition with valproic acid downregulates ost...
Published: January, 2014
Abstract: Adult mesenchymal stem cells, such as dental pulp stem cells, are of great interest for cell-based tissue engineering strategies because they can d... Read more »
Hypermethylation of the alternative AWT1 promoter in hematological ...
Published: January, 2014
Abstract: BACKGROUND: Wilms tumor 1 (WT1) is over-expressed in numerous cancers with respect to normal cells, and has either a tumor suppressor or oncogenic ... Read more »
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Antibody
CLOCK:BMAL1 is a pioneer-like transcription factor.
Published: January, 2014
Abstract: The mammalian circadian clock relies on the master genes CLOCK and BMAL1 to drive rhythmic gene expression and regulate biological functions under ... Read more »
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Bioruptor Chromatin Shearing ChIP-seq Bioruptor Plus
Integrated transcriptome analysis of mouse spermatogenesis.
Published: January, 2014
Abstract: BACKGROUND: Differentiation of primordial germ cells into mature spermatozoa proceeds through multiple stages, one of the most important of which i... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The genome-wide landscape of DNA methylation and hydroxymethylation...
Published: January, 2014
Abstract: Sleep is critical for normal brain function and mental health. However, the molecular mechanisms mediating the impact of sleep loss on both cogniti... Read more »
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DNA shearing Bioruptor
Genome-wide profiling of transcription factor binding and epigeneti...
Published: January, 2014
Abstract: The recent advances in high-throughput sequencing combined with various other technologies have allowed detailed and genome-wide insight into the t... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Genome-wide data (ChIP-seq) enabled identification of cell wall-rel...
Published: January, 2014
Abstract: BACKGROUND: Identifying the target genes of transcription factors is important for unraveling regulatory networks in all types of organisms. Our in... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Analyzing the functions and structure of the human lipodystrophy pr...
Published: January, 2014
Abstract: Disruption of the gene BSCL2, which encodes the protein seipin, causes severe generalized lipodystrophy in humans with a near complete absence of a... Read more »
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Bioruptor Cell Lysis
Microbes in the neonatal intensive care unit resemble those found i...
Published: January, 2014
Abstract: BACKGROUND: The source inoculum of gastrointestinal tract (GIT) microbes is largely influenced by delivery mode in full-term infants, but these inf... Read more »
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DNA shearing Bioruptor
Differential methylation of the TRPA1 promoter in pain sensitivity.
Published: January, 2014
Abstract: Chronic pain is a global public health problem, but the underlying molecular mechanisms are not fully understood. Here we examine genome-wide DNA m... Read more »
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DNA shearing Bioruptor IP-Star MagMeDIP kit
Negative regulation of the peptidylarginine deiminase type IV promo...
Published: January, 2014
Abstract: High titers of anti-citrullinated protein/peptide antibodies (ACPAs) have been detected in sera of rheumatoid arthritis (RA) patients, implicating ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Differential expression of histone H3 genes and selective associati...
Published: January, 2014
Abstract: BACKGROUND: Regulation of chromatin structure involves deposition of selective histone variants into nucleosome arrays. Numerous histone H3 variant... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Array-based assay detects genome-wide 5-mC and 5-hmC in the brains ...
Published: January, 2014
Abstract: BACKGROUND: Methylation on the fifth position of cytosine (5-mC) is an essential epigenetic mark that is linked to both normal neurodevelopment and... Read more »
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DNA shearing Bioruptor Bioruptor Plus
Viral aetiology influenza like illnesses in Santa Cruz, Bolivia (20...
Published: January, 2014
Abstract: BACKGROUND: Acute respiratory infections represent a serious public health issue worldwide but virological aetiologies of Influenza Like Illnesses ... Read more »
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DNA shearing Bioruptor
Strand-specific RNA-Seq reveals widespread and developmentally regu...
Published: January, 2014
Abstract: BACKGROUND: Advances in high-throughput sequencing have led to the discovery of widespread transcription of natural antisense transcripts (NATs) in... Read more »
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DNA shearing Bioruptor
Histone Deacetylase inhibition with Valproic Acid down-regulates Os...
Published: January, 2014
Abstract: Adult mesenchymal stem cells, such as dental pulp stem cells, are of great interest for cell-based tissue engineering strategies because they can d... Read more »
Tags
Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
Demethylation of the human eotaxin-3 gene promoter leads to the ele...
Published: January, 2014
Abstract: DNA demethylation has been primarily studied in the context of development biology, cell fate, and cancer, with less attention on inflammation. In ... Read more »
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IP-Star IP-Star Compact
Histone Deacetylase Classes I and II Regulate Kaposi's Sarcoma-Asso...
Published: January, 2014
Abstract: In primary effusion lymphoma (PEL) cells infected with latent Kaposi's sarcoma-associated herpesvirus (KSHV), the promoter of the viral lytic switc... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Recessive mutations in a distal PTF1A enhancer cause isolated pancr...
Published: January, 2014
Abstract: The contribution of cis-regulatory mutations to human disease remains poorly understood. Whole-genome sequencing can identify all noncoding variant... Read more »
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DNA shearing Bioruptor
Meis2 is a Pax6 co-factor in neurogenesis and dopaminergic periglom...
Published: January, 2014
Abstract: Meis homeodomain transcription factors control cell proliferation, cell fate specification and differentiation in development and disease. Previous... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
Regulation of the neuronal transcription factor NPAS4 by REST and m...
Published: January, 2014
Abstract: NPAS4 is a brain restricted, activity-induced transcription factor which regulates the expression of inhibitory synapse genes to control homeostati... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Human cytomegalovirus major immediate early 1 protein targets host ...
Published: January, 2014
Abstract: The 72-kDa immediate early 1 (IE1) protein encoded by human cytomegalovirus (hCMV) is a nuclearly localized promiscuous regulator of viral and cell... Read more »
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Bioruptor Chromatin Shearing
Large conserved domains of low DNA methylation maintained by Dnmt3a.
Published: January, 2014
Abstract: Gains and losses in DNA methylation are prominent features of mammalian cell types. To gain insight into the mechanisms that promote shifts in DNA ... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Eic1 links Mis18 with the CCAN/Mis6/Ctf19 complex to promote CENP-A...
Published: January, 2014
Abstract: CENP-A chromatin forms the foundation for kinetochore assembly. Replication-independent incorporation of CENP-A at centromeres depends on its chape... Read more »
Inactivating CUX1 mutations promote tumorigenesis.
Published: January, 2014
Abstract: A major challenge in cancer genetics is to determine which low-frequency somatic mutations are drivers of tumorigenesis. Here we interrogate the ge... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
Genome-wide methylation and gene expression changes in newborn rats...
Published: December, 2013
Abstract: A large body of evidence from human and animal studies demonstrates that the maternal diet during pregnancy can programme physiological and metabol... Read more »
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DNA shearing Bioruptor MethylCap
Molecular mechanisms of regulation and action of microRNA-199a in t...
Published: December, 2013
Abstract: MicroRNA-199a (miRNA-199a) has been shown to have comprehensive functions and behave differently in different systems and diseases. It is encoded b... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Anti-androgen resistance in prostate cancer cells chronically induc...
Published: December, 2013
Abstract: Chronic inflammation has been linked to cancer initiation and progression in a variety of tissues, yet the impact of acute and chronic inflammatory... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Novel CTCF binding at a site in exon1A of BCL6 is associated with a...
Published: December, 2013
Abstract: BCL6 is a zinc-finger transcriptional repressor, which is highly expressed in germinal centre B-cells and is essential for germinal centre formatio... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Rapid and pervasive changes in genome-wide enhancer usage during ma...
Published: December, 2013
Abstract: Enhancers are distal regulatory elements that can activate tissue-specific gene expression and are abundant throughout mammalian genomes. Although ... Read more »
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Bioruptor Chromatin Shearing ChIP-seq

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