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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

The multifunctional Ccr4-Not complex directly promotes transcriptio...
Published: March, 2011
Abstract: The Ccr4-Not complex has been implicated in the control of multiple steps of mRNA metabolism; however, its functions in transcription remain ambigu... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
5-Hydroxymethylcytosine in the mammalian zygote is linked with epig...
Published: March, 2011
Abstract: The epigenomes of early mammalian embryos are extensively reprogrammed to acquire a totipotent developmental potential. A major initial event in th... Read more »
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Antibody
Role for miR-204 in human pulmonary arterial hypertension.
Published: March, 2011
Abstract: Pulmonary arterial hypertension (PAH) is characterized by enhanced proliferation and reduced apoptosis of pulmonary artery smooth muscle cells (PAS... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Cutting edge: persistently open chromatin at effector gene loci in ...
Published: March, 2011
Abstract: Memory CD8(+) T cells are characterized by more rapid and robust effector function upon infection compared with naive T cells, but factors governin... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Histone H3 lysine 9 trimethylation and HP1γ favor inclusion of alte...
Published: March, 2011
Abstract: Pre-messenger RNAs (pre-mRNAs) maturation is initiated cotranscriptionally. It is therefore conceivable that chromatin-borne information participat... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Ah receptor antagonism inhibits constitutive and cytokine inducible...
Published: March, 2011
Abstract: There is increasing evidence that the aryl hydrocarbon receptor (AHR) plays a role in tumor progression through numerous mechanisms. We have previo... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of ...
Published: March, 2011
Abstract: The regulation of neutrophil lifespan by induction of apoptosis is critical for maintaining an effective host response and preventing excessive inf... Read more »
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Bioruptor Cell Lysis
SNP discovery in black cottonwood (Populus trichocarpa) by populati...
Published: March, 2011
Abstract: The western black cottonwood (Populus trichocarpa) was the first tree to have its genome fully sequenced and has emerged as the model species for t... Read more »
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DNA shearing Bioruptor
EpiChIP: gene-by-gene quantification of epigenetic modification lev...
Published: March, 2011
Abstract: The combination of chromatin immunoprecipitation with next-generation sequencing technology (ChIP-seq) is a powerful and increasingly popular metho... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
DNA methyltransferase 1, cytosine methylation, and cytosine hydroxy...
Published: March, 2011
Abstract: Mitochondrial DNA (mtDNA) has been reported to contain 5-methylcytosine (5mC) at CpG dinucleotides, as in the nuclear genome, but neither the mecha... Read more »
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DNA shearing Bioruptor
High-resolution genome-wide in vivo footprinting of diverse transcr...
Published: March, 2011
Abstract: Regulation of gene transcription in diverse cell types is determined largely by varied sets of cis-elements where transcription factors bind. Here ... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Synergism between DNA methylation and macroH2A1 occupancy in epigen...
Published: March, 2011
Abstract: Promoter hypermethylation and heterochromatinization is a frequent event leading to gene inactivation and tumorigenesis. At the molecular level, in... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Role for cohesin in the formation of a heterochromatic domain at fi...
Published: March, 2011
Abstract: Increasing evidence implicates cohesin in the control of gene expression. Here we report the first analysis of cohesin-dependent gene regulation in... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Estrogen receptor α-mediated transcription induces cell cycle-depen...
Published: March, 2011
Abstract: Prolonged exposure to estrogen increases breast cancer risk. Estrogen is known to induce chromosomal aberrations, yet the mechanisms by which estro... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
A critical role for the protein phosphatase 2A B'α regulatory subun...
Published: March, 2011
Abstract: Sphingosine kinase 1 (SK1) is an important regulator of cellular signalling that has gained recent attention as a potential target for anti-cancer ... Read more »
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Bioruptor Cell Lysis
Involvement of placental growth factor in Wallerian degeneration.
Published: March, 2011
Abstract: Wallerian degeneration (WD) is an inflammatory process of nerve degeneration, which occurs more rapidly in the peripheral nervous system compared w... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Aurora kinase B activity is modulated by thyroid hormone during tra...
Published: March, 2011
Abstract: Covalent histone modifications clearly play an essential role in ligand-dependent transcriptional regulation by nuclear receptors. One of the predo... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
H3 lysine 4 is acetylated at active gene promoters and is regulated...
Published: March, 2011
Abstract: Methylation of histone H3 lysine 4 (H3K4me) is an evolutionarily conserved modification whose role in the regulation of gene expression has been ex... Read more »
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Bioruptor Chromatin Shearing
TNFR1 is essential for CD40, but not for lipopolysaccharide-induced...
Published: March, 2011
Abstract: Autoimmune and infectious diseases are associated with behavioral changes referred to as sickness behavior syndrome (SBS). In autoimmunity, the gen... Read more »
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Chromatin Shearing ChIP-qPCR IPure kit
Epigenetic silencing mediated through activated PI3K/AKT signaling ...
Published: March, 2011
Abstract: Trimethylation of histone 3 lysine 27 (H3K27me3) is a critical epigenetic mark for the maintenance of gene silencing. Additional accumulation of DN... Read more »
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Antibody 5mC (C15200081)
Stress induces parallel changes in corticotrophin-releasing hormone...
Published: March, 2011
Abstract: Recent studies in vitro have shown that the cAMP response element-binding (CREB) co-activator, transducer of regulated CREB activity (TORC), is req... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Paired box gene 5 is a novel tumor suppressor in hepatocellular car...
Published: March, 2011
Abstract: The paired box 5 (PAX5) is a member of PAX transcription factors family involved in the regulation of embryonic development. However, the role of P... Read more »
Interactions among Polycomb domains are guided by chromosome archit...
Published: March, 2011
Abstract: Polycomb group (PcG) proteins bind and regulate hundreds of genes. Previous evidence has suggested that long-range chromatin interactions may contr... Read more »
Embryonic lethal phenotype reveals a function of TDG in maintaining...
Published: February, 2011
Abstract: Thymine DNA glycosylase (TDG) is a member of the uracil DNA glycosylase (UDG) superfamily of DNA repair enzymes. Owing to its ability to excise thy... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody
miRNA-132 orchestrates chromatin remodeling and translational contr...
Published: February, 2011
Abstract: Mammalian circadian rhythms are synchronized to the external time by daily resetting of the suprachiasmatic nucleus (SCN) in response to light. As ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Characterization of the contradictory chromatin signatures at the 3...
Published: February, 2011
Abstract: The H3K9me3 histone modification is often found at promoter regions, where it functions to repress transcription. However, we have previously shown... Read more »
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Bioruptor Chromatin Shearing ChIP-seq Antibody
Mitogen-activated protein kinases ERK 1/2- and p38-GATA4 pathways m...
Published: February, 2011
Abstract: Several genes, including fibroblast growth factor 2 (FGF2), are up-regulated in the hypertrophic heart. However, the molecular mechanisms responsib... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
9p21 DNA variants associated with coronary artery disease impair in...
Published: February, 2011
Abstract: Genome-wide association studies have identified single nucleotide polymorphisms (SNPs) in the 9p21 gene desert associated with coronary artery dise... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Deregulation of Aiolos expression in chronic lymphocytic leukemia i...
Published: February, 2011
Abstract: Chronic lymphocytic leukemia (CLL) is characterized by a clonal accumulation of mature neoplastic B cells that are resistant to apoptosis. Aiolos, ... Read more »
The antiprogestin Lonaprisan inhibits breast cancer cell proliferat...
Published: February, 2011
Abstract: The ovarian steroid hormone progesterone is essential for normal mammary gland physiology but may also play a role in breast cancer. Highly potent ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR

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