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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

The histone methyltransferase Dot1 is required for DNA damage repai...
Published: January, 2011
Abstract: Posttranslational histone modifications play an important role in modulating gene expression and chromatin structure. Here we report the identifica... Read more »
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Antibody
Integrative features of the yeast phosphoproteome and protein-prote...
Published: January, 2011
Abstract: Following recent advances in high-throughput mass spectrometry (MS)-based proteomics, the numbers of identified phosphoproteins and their phosphosi... Read more »
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Cell Lysis
Inhibition of suppressive T cell factor 1 (TCF-1) isoforms in naive...
Published: January, 2011
Abstract: The Wnt pathway transcription factor T cell factor 1 (TCF-1) plays essential roles in the control of several developmental processes, including T c... Read more »
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Antibody LowCell ChIP kit
Comprehensive profiling of zebrafish hepatic proximal promoter CpG ...
Published: January, 2011
Abstract: BACKGROUND: DNA methylation is an epigenetic mechanism associated with regulation of gene expression and it is modulated during chemical carcinogen... Read more »
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MagMeDIP kit
Chromatin Immunoprecipitation (ChIP): Revisiting the Efficacy of Sa...
Published: January, 2011
Abstract: The "quantitative" ChIP, a tool commonly used to study protein-DNA interactions in cells and tissue, is a difficult assay often plagued with techni... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Identification and characterisation of a novel adhesin Ifp in Yersi...
Published: January, 2011
Abstract: BACKGROUND: In order to identify new virulence determinants in Y. pseudotuberculosis a comparison between its genome and that of Yersinia pestis wa... Read more »
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Bioruptor Cell Lysis
Local de novo assembly of RAD paired-end contigs using short sequen...
Published: January, 2011
Abstract: Despite the power of massively parallel sequencing platforms, a drawback is the short length of the sequence reads produced. We demonstrate that sh... Read more »
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DNA shearing Bioruptor
Characterisation of genome-wide PLZF/RARA target genes.
Published: January, 2011
Abstract: The PLZF/RARA fusion protein generated by the t(11;17)(q23;q21) translocation in acute promyelocytic leukaemia (APL) is believed to act as an oncog... Read more »
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Bioruptor Chromatin Shearing Antibody H3K4me3 (C15410003)
Performance of microarray and liquid based capture methods for targ...
Published: January, 2011
Abstract: Targeted sequencing is a cost-efficient way to obtain answers to biological questions in many projects, but the choice of the enrichment method to ... Read more »
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DNA shearing Bioruptor
The Saccharomyces cerevisiae histone chaperone Rtt106 mediates the ...
Published: January, 2011
Abstract: BACKGROUND: In Saccharomyces cerevisiae, three out of the four histone gene pairs (HTA1-HTB1, HHT1-HHF1, and HHT2-HHF2) are regulated by the HIR co... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
ChIP-chip versus ChIP-seq: lessons for experimental design and data...
Published: January, 2011
Abstract: BACKGROUND: Chromatin immunoprecipitation (ChIP) followed by microarray hybridization (ChIP-chip) or high-throughput sequencing (ChIP-seq) allows g... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Dot1 binding induces chromatin rearrangements by histone methylatio...
Published: January, 2011
Abstract: UNLABELLED: BACKGROUND: Methylation of histone H3 lysine 79 (H3K79) by Dot1 is highly conserved among species and has been associated with both ge... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Affinity-based enrichment strategies to assay methyl-CpG binding ac...
Published: January, 2011
Abstract: UNLABELLED: ABSTRACT: BACKGROUND: DNA methylation is a widespread epigenetic modification in vertebrate genomes. Genomic sites of DNA methylation c... Read more »
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DNA shearing Bioruptor
Phenobarbital mediates an epigenetic switch at the constitutive and...
Published: January, 2011
Abstract: Evidence suggests that epigenetic perturbations are involved in the adverse effects associated with some drugs and toxicants, including certain cla... Read more »
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DNA shearing Bioruptor
Role of p53 serine 46 in p53 target gene regulation.
Published: January, 2011
Abstract: The tumor suppressor p53 plays a crucial role in cellular growth control inducing a plethora of different response pathways. The molecular mechanis... Read more »
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Bioruptor Chromatin Shearing ChIP-seq Antibody
Phosphorylation of the MBF repressor Yox1p by the DNA replication c...
Published: January, 2011
Abstract: BACKGROUND: In fission yeast Schizosaccharomyces pombe G1/S cell-cycle regulated transcription depends upon MBF. A negative feedback loop involving... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Herpes simplex virus induces the marked up-regulation of the zinc f...
Published: January, 2011
Abstract: BACKGROUND: Herpes simplex viruses (HSVs) rapidly shut off macromolecular synthesis in host cells. In contrast, global microarray analyses have sho... Read more »
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Chromatin Shearing ChIP-qPCR
Effects of nickel treatment on H3K4 trimethylation and gene express...
Published: January, 2011
Abstract: Occupational exposure to nickel compounds has been associated with lung and nasal cancers. We have previously shown that exposure of the human lung... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Enhanced chromatin accessibility and recruitment of JUNB mediate th...
Published: January, 2011
Abstract: Nuclear factor of activated T cells (NFAT) is a family of transcription factors composed of five proteins. Among them, NFAT1 is a predominant NFAT ... Read more »
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DNA shearing Bioruptor Antibody
Necdin, a Negative Growth Regulator, Is a Novel STAT3 Target Gene D...
Published: January, 2011
Abstract: Cytokine and growth factor signaling pathways involving STAT3 are frequently constitutively activated in many human primary tumors, and are known f... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
RNA sequencing reveals two major classes of gene expression levels ...
Published: January, 2011
Abstract: The expression level of a gene is often used as a proxy for determining whether the protein or RNA product is functional in a cell or tissue. There... Read more »
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DNA shearing Bioruptor
Wnt/β-catenin signaling pathway is a direct enhancer of thyroid tra...
Published: January, 2011
Abstract: The Wnt/β-catenin signaling pathway is involved in the normal development of thyroid gland, but its disregulation provokes the appearance of severa... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Identification of novel SNPs in glioblastoma using targeted reseque...
Published: January, 2011
Abstract: High-throughput sequencing opens avenues to find genetic variations that may be indicative of an increased risk for certain diseases. Linking these... Read more »
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DNA shearing Bioruptor
Sleep Loss Reduces the DNA-Binding of BMAL1, CLOCK, and NPAS2 to Sp...
Published: January, 2011
Abstract: We have previously demonstrated that clock genes contribute to the homeostatic aspect of sleep regulation. Indeed, mutations in some clock genes mo... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Pluripotency factor binding and Tsix expression act synergistically...
Published: January, 2011
Abstract: UNLABELLED: ABSTRACT: BACKGROUND: Expression of Xist, the master regulator of X chromosome inactivation, is extinguished in pluripotent cells, a pr... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Convergence of miRNA Expression Profiling, α-Synuclein Interacton a...
Published: January, 2011
Abstract: miRNAs were recently implicated in the pathogenesis of numerous diseases, including neurological disorders such as Parkinson's disease (PD). miRNAs... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
MLL-AF9 and MLL-ENL alter the dynamic association of transcriptiona...
Published: January, 2011
Abstract: OBJECTIVE: The aim of this study was to better understand how mixed lineage leukemia (MLL) fusion proteins deregulate the expression of genes criti... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Microplate-based platform for combined chromatin and DNA methylatio...
Published: January, 2011
Abstract: UNLABELLED: ABSTRACT: BACKGROUND: The processes that compose expression of a given gene are far more complex than previously thought presenting unp... Read more »
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Bioruptor Chromatin Shearing Antibody
Global analysis of DNA methylation by methyl-capture sequencing rev...
Published: January, 2011
Abstract: Cisplatin resistance is one of the major reasons leading to the high death rate of ovarian cancer. Methyl-Capture sequencing (MethylCap-seq), which... Read more »
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DNA shearing Bioruptor
ZEB1 limits adenoviral infectability by transcriptionally repressin...
Published: January, 2011
Abstract: BACKGROUND: We have previously reported that RAS-MEK (Cancer Res. 2003 May 1;63(9):2088-95) and TGF-β (Cancer Res. 2006 Feb 1;66(3):1648-57) signal... Read more »
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Chromatin Shearing ChIP-qPCR

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  • FASEB Biological Methylation: Fundamental Mechanisms
    Porto, Portugal
    Jul 28-Aug 1, 2024
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