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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Clustering heterochromatin: Sir3 promotes telomere clustering indep...
Published: February, 2011
Abstract: A general feature of the nucleus is the organization of repetitive deoxyribonucleic acid sequences in clusters concentrating silencing factors. In ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
ΔNp63α is an oncogene that targets chromatin remodeler Lsh to drive...
Published: February, 2011
Abstract: The p53 homolog p63 is essential for development, yet its role in cancer is not clear. We discovered that p63 deficiency evokes the tumor-suppressi... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Analysis of Histone Exchange during Chromatin Purification.
Published: February, 2011
Abstract: Central to the study of chromosome biology are techniques that permit the purification of small chromatin sections for analysis of associated DNA a... Read more »
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Bioruptor Chromatin Shearing
DNA methylation and histone H3-K9 modifications contribute to MUC17...
Published: February, 2011
Abstract: MUC17 glycoprotein is a membrane-associated mucin that is mainly expressed in the digestive tract. It has been suggested that MUC17 expression is c... Read more »
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Chromatin Shearing ChIP-qPCR
Multiplex target enrichment using DNA indexing for ultra-high throu...
Published: February, 2011
Abstract: Screening large numbers of target regions in multiple DNA samples for sequence variation is an important application of next-generation sequencing ... Read more »
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DNA shearing Bioruptor
Rapid and reversible light-mediated chromatin modifications of Arab...
Published: February, 2011
Abstract: Recent genome-wide surveys showed that acetylation of H3K9 and H3K27 is correlated with gene activation during deetiolation of Arabidopsis thaliana... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Control of chromatin structure by spt6: different consequences in c...
Published: February, 2011
Abstract: Spt6 is a highly conserved factor required for normal transcription and chromatin structure. To gain new insights into the roles of Spt6, we measur... Read more »
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Chromatin Shearing ChIP-qPCR
A human pathology-related mutation prevents import of an aminoacyl-...
Published: February, 2011
Abstract: Mutations in the nuclear gene coding for the mitochondrial aspartyl-tRNA synthetase, a key enzyme for mitochondrial translation, are correlated wit... Read more »
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Bioruptor Mitochondria disruption
Expression of P. falciparum var genes involves exchange of the hist...
Published: February, 2011
Abstract: Plasmodium falciparum employs antigenic variation to evade the human immune response by switching the expression of different variant surface antig... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Rescue of gene expression by modified REST decoy oligonucleotides i...
Published: February, 2011
Abstract: Transcriptional dysfunction is a prominent hallmark of Huntington's disease (HD). Several transcription factors have been implicated in the aetiolo... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Plasticity in patterns of histone modifications and chromosomal pro...
Published: February, 2011
Abstract: Eukaryotic genomes are packaged in two basic forms, euchromatin and heterochromatin. We have examined the composition and organization of Drosophil... Read more »
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Bioruptor Chromatin Shearing
Facultative heterochromatin formation at the IL-1 beta promoter in ...
Published: February, 2011
Abstract: The clinical phenotype in sepsis that is observed as LPS tolerance is determined by silencing of pro-inflammatory genes like IL-1 beta (IL-1β). Thi... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The cardiac transcription network modulated by Gata4, Mef2a, Nkx2.5...
Published: February, 2011
Abstract: The transcriptome, as the pool of all transcribed elements in a given cell, is regulated by the interaction between different molecular levels, inv... Read more »
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LowCell ChIP kit
Genome-wide mapping of the HY5-mediated gene networks in Arabidopsi...
Published: February, 2011
Abstract: LONG HYPOCOTYL 5 (HY5) is a basic leucine zipper transcription factor (TF) that functions downstream of multiple families of photoreceptors. Mutati... Read more »
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Bioruptor Chromatin Shearing
Epigenetic control of vascular smooth muscle cells in Marfan and no...
Published: February, 2011
Abstract: AIMS: Human thoracic aortic aneurysms (TAAs) are characterized by extracellular matrix breakdown associated with progressive smooth muscle cell (SM... Read more »
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Antibody Histone ChIP kit
Comprehensive analysis of DNA-methylation in mammalian tissues usin...
Published: February, 2011
Abstract: Genome-wide mapping of epigenetic changes is essential for understanding the mechanisms involved in gene regulation during cell differentiation and... Read more »
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DNA shearing Bioruptor Antibody
Recombineering BAC transgenes for protein tagging.
Published: February, 2011
Abstract: Protein tagging offers many advantages for proteomic and regulomic research, particularly due to the use of generic and highly sensitive methods th... Read more »
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Bioruptor Cell Lysis Western Blot
Cell cycle regulated expression of NCoR might control cyclic expres...
Published: January, 2011
Abstract: In this work we have studied the mechanisms of regulation of expression of androgen receptor (AR) target genes. We have used an immortalized non-tu... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The histone methyltransferase Dot1 is required for DNA damage repai...
Published: January, 2011
Abstract: Posttranslational histone modifications play an important role in modulating gene expression and chromatin structure. Here we report the identifica... Read more »
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Antibody
Integrative features of the yeast phosphoproteome and protein-prote...
Published: January, 2011
Abstract: Following recent advances in high-throughput mass spectrometry (MS)-based proteomics, the numbers of identified phosphoproteins and their phosphosi... Read more »
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Cell Lysis
Inhibition of suppressive T cell factor 1 (TCF-1) isoforms in naive...
Published: January, 2011
Abstract: The Wnt pathway transcription factor T cell factor 1 (TCF-1) plays essential roles in the control of several developmental processes, including T c... Read more »
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Antibody LowCell ChIP kit
Comprehensive profiling of zebrafish hepatic proximal promoter CpG ...
Published: January, 2011
Abstract: BACKGROUND: DNA methylation is an epigenetic mechanism associated with regulation of gene expression and it is modulated during chemical carcinogen... Read more »
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MagMeDIP kit
Chromatin Immunoprecipitation (ChIP): Revisiting the Efficacy of Sa...
Published: January, 2011
Abstract: The "quantitative" ChIP, a tool commonly used to study protein-DNA interactions in cells and tissue, is a difficult assay often plagued with techni... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Identification and characterisation of a novel adhesin Ifp in Yersi...
Published: January, 2011
Abstract: BACKGROUND: In order to identify new virulence determinants in Y. pseudotuberculosis a comparison between its genome and that of Yersinia pestis wa... Read more »
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Bioruptor Cell Lysis
Local de novo assembly of RAD paired-end contigs using short sequen...
Published: January, 2011
Abstract: Despite the power of massively parallel sequencing platforms, a drawback is the short length of the sequence reads produced. We demonstrate that sh... Read more »
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DNA shearing Bioruptor
Characterisation of genome-wide PLZF/RARA target genes.
Published: January, 2011
Abstract: The PLZF/RARA fusion protein generated by the t(11;17)(q23;q21) translocation in acute promyelocytic leukaemia (APL) is believed to act as an oncog... Read more »
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Bioruptor Chromatin Shearing Antibody H3K4me3 (C15410003)
Performance of microarray and liquid based capture methods for targ...
Published: January, 2011
Abstract: Targeted sequencing is a cost-efficient way to obtain answers to biological questions in many projects, but the choice of the enrichment method to ... Read more »
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DNA shearing Bioruptor
The Saccharomyces cerevisiae histone chaperone Rtt106 mediates the ...
Published: January, 2011
Abstract: BACKGROUND: In Saccharomyces cerevisiae, three out of the four histone gene pairs (HTA1-HTB1, HHT1-HHF1, and HHT2-HHF2) are regulated by the HIR co... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
ChIP-chip versus ChIP-seq: lessons for experimental design and data...
Published: January, 2011
Abstract: BACKGROUND: Chromatin immunoprecipitation (ChIP) followed by microarray hybridization (ChIP-chip) or high-throughput sequencing (ChIP-seq) allows g... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Dot1 binding induces chromatin rearrangements by histone methylatio...
Published: January, 2011
Abstract: UNLABELLED: BACKGROUND: Methylation of histone H3 lysine 79 (H3K79) by Dot1 is highly conserved among species and has been associated with both ge... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR

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