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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Affinity-based enrichment strategies to assay methyl-CpG binding ac...
Published: January, 2011
Abstract: UNLABELLED: ABSTRACT: BACKGROUND: DNA methylation is a widespread epigenetic modification in vertebrate genomes. Genomic sites of DNA methylation c... Read more »
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DNA shearing Bioruptor
Phenobarbital mediates an epigenetic switch at the constitutive and...
Published: January, 2011
Abstract: Evidence suggests that epigenetic perturbations are involved in the adverse effects associated with some drugs and toxicants, including certain cla... Read more »
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DNA shearing Bioruptor
Role of p53 serine 46 in p53 target gene regulation.
Published: January, 2011
Abstract: The tumor suppressor p53 plays a crucial role in cellular growth control inducing a plethora of different response pathways. The molecular mechanis... Read more »
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Bioruptor Chromatin Shearing ChIP-seq Antibody
Phosphorylation of the MBF repressor Yox1p by the DNA replication c...
Published: January, 2011
Abstract: BACKGROUND: In fission yeast Schizosaccharomyces pombe G1/S cell-cycle regulated transcription depends upon MBF. A negative feedback loop involving... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Herpes simplex virus induces the marked up-regulation of the zinc f...
Published: January, 2011
Abstract: BACKGROUND: Herpes simplex viruses (HSVs) rapidly shut off macromolecular synthesis in host cells. In contrast, global microarray analyses have sho... Read more »
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Chromatin Shearing ChIP-qPCR
Effects of nickel treatment on H3K4 trimethylation and gene express...
Published: January, 2011
Abstract: Occupational exposure to nickel compounds has been associated with lung and nasal cancers. We have previously shown that exposure of the human lung... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Enhanced chromatin accessibility and recruitment of JUNB mediate th...
Published: January, 2011
Abstract: Nuclear factor of activated T cells (NFAT) is a family of transcription factors composed of five proteins. Among them, NFAT1 is a predominant NFAT ... Read more »
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DNA shearing Bioruptor Antibody
Necdin, a Negative Growth Regulator, Is a Novel STAT3 Target Gene D...
Published: January, 2011
Abstract: Cytokine and growth factor signaling pathways involving STAT3 are frequently constitutively activated in many human primary tumors, and are known f... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
RNA sequencing reveals two major classes of gene expression levels ...
Published: January, 2011
Abstract: The expression level of a gene is often used as a proxy for determining whether the protein or RNA product is functional in a cell or tissue. There... Read more »
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DNA shearing Bioruptor
Wnt/β-catenin signaling pathway is a direct enhancer of thyroid tra...
Published: January, 2011
Abstract: The Wnt/β-catenin signaling pathway is involved in the normal development of thyroid gland, but its disregulation provokes the appearance of severa... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Identification of novel SNPs in glioblastoma using targeted reseque...
Published: January, 2011
Abstract: High-throughput sequencing opens avenues to find genetic variations that may be indicative of an increased risk for certain diseases. Linking these... Read more »
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DNA shearing Bioruptor
Sleep Loss Reduces the DNA-Binding of BMAL1, CLOCK, and NPAS2 to Sp...
Published: January, 2011
Abstract: We have previously demonstrated that clock genes contribute to the homeostatic aspect of sleep regulation. Indeed, mutations in some clock genes mo... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Pluripotency factor binding and Tsix expression act synergistically...
Published: January, 2011
Abstract: UNLABELLED: ABSTRACT: BACKGROUND: Expression of Xist, the master regulator of X chromosome inactivation, is extinguished in pluripotent cells, a pr... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Convergence of miRNA Expression Profiling, α-Synuclein Interacton a...
Published: January, 2011
Abstract: miRNAs were recently implicated in the pathogenesis of numerous diseases, including neurological disorders such as Parkinson's disease (PD). miRNAs... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
MLL-AF9 and MLL-ENL alter the dynamic association of transcriptiona...
Published: January, 2011
Abstract: OBJECTIVE: The aim of this study was to better understand how mixed lineage leukemia (MLL) fusion proteins deregulate the expression of genes criti... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Microplate-based platform for combined chromatin and DNA methylatio...
Published: January, 2011
Abstract: UNLABELLED: ABSTRACT: BACKGROUND: The processes that compose expression of a given gene are far more complex than previously thought presenting unp... Read more »
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Bioruptor Chromatin Shearing Antibody
Global analysis of DNA methylation by methyl-capture sequencing rev...
Published: January, 2011
Abstract: Cisplatin resistance is one of the major reasons leading to the high death rate of ovarian cancer. Methyl-Capture sequencing (MethylCap-seq), which... Read more »
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DNA shearing Bioruptor
ZEB1 limits adenoviral infectability by transcriptionally repressin...
Published: January, 2011
Abstract: BACKGROUND: We have previously reported that RAS-MEK (Cancer Res. 2003 May 1;63(9):2088-95) and TGF-β (Cancer Res. 2006 Feb 1;66(3):1648-57) signal... Read more »
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Chromatin Shearing ChIP-qPCR
Epigenetic regulation of miR-212 expression in lung cancer.
Published: January, 2011
Abstract: Many studies have shown that microRNA expression in cancer may be regulated by epigenetic events. Recently, we found that in lung cancer miR-212 wa... Read more »
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Chromatin Shearing ChIP-qPCR Antibody LowCell ChIP kit
Epigenetic activation of SOX11 in lymphoid neoplasms by histone mod...
Published: January, 2011
Abstract: Recent studies have shown aberrant expression of SOX11 in various types of aggressive B-cell neoplasms. To elucidate the molecular mechanisms leadi... Read more »
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Antibody LowCell ChIP kit
Proteomic Analysis of Anti-inflammatory Effects of a Kampo (Japanes...
Published: January, 2011
Abstract: Effects of a Kampo (Japanese herbal) medicine "shoseiryuto (SST, xiao-qing-long-tang in Chinese)", which has been used for the treatment of allergi... Read more »
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Tissue Homogenization
Control of flowering and cell fate by LIF2, an RNA binding partner ...
Published: January, 2011
Abstract: Polycomb Repressive Complexes (PRC) modulate the epigenetic status of key cell fate and developmental regulators in eukaryotes. The chromo domain p... Read more »
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Chromatin Shearing ChIP-qPCR IPure kit
Unrestricted somatic stem cells (USSC) from human umbilical cord bl...
Published: January, 2011
Abstract: Unrestricted somatic stem cells (USSC) from human cord blood display a broad differentiation potential for ectodermal, mesodermal, and endodermal c... Read more »
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MeDIP kit
Selective chemical labeling reveals the genome-wide distribution of...
Published: January, 2011
Abstract: In contrast to 5-methylcytosine (5-mC), which has been studied extensively, little is known about 5-hydroxymethylcytosine (5-hmC), a recently ident... Read more »
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DNA shearing Bioruptor
Epigenetic regulation on the 5'-proximal CpG island of human porcin...
Published: January, 2011
Abstract: Porcine endogenous retroviruses (PERVs) have been considered one of the major risks of xenotransplantation from pigs to humans. PERV-A efficiently ... Read more »
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Antibody
Direct recruitment of insulin receptor and ERK signaling cascade to...
Published: January, 2011
Abstract: OBJECTIVE: Insulin receptor (IR) translocates to the nucleus, but its recruitment to gene loci has not been demonstrated. Here, we tested the hypot... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Phosphatidylinositol 3-kinase (PI3K) signaling via glycogen synthas...
Published: December, 2010
Abstract: Glycogen synthase kinase-3 (Gsk-3) isoforms, Gsk-3α and Gsk-3β, are constitutively active, largely inhibitory kinases involved in signal transducti... Read more »
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Bioruptor Cell Lysis Western Blot
Tiling histone H3 lysine 4 and 27 methylation in zebrafish using hi...
Published: December, 2010
Abstract: BACKGROUND: Uncovering epigenetic states by chromatin immunoprecipitation and microarray hybridization (ChIP-chip) has significantly contributed to... Read more »
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Antibody H3K4me3 (C15410003)
H2A.Z demarcates intergenic regions of the plasmodium falciparum ep...
Published: December, 2010
Abstract: Epigenetic regulatory mechanisms and their enzymes are promising targets for malaria therapeutic intervention; however, the epigenetic component of... Read more »
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DNA shearing Bioruptor Antibody
The role of the basic helix-loop-helix transcription factor Dec1 in...
Published: December, 2010
Abstract: Naturally occurring regulatory T (Treg) cells play a central role in the maintenance of immune homeostasis and in restraining the development of sp... Read more »
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LowCell ChIP kit

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