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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Distinct silencer states generate epigenetic states of heterochroma...
Published: August, 2022
Abstract: Heterochromatic loci can exhibit different transcriptional states in genetically identical cells. A popular model posits that the inheritance of mo... Read more »
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Antibody
RAD51 protects human cells from transcription-replication conflicts.
Published: August, 2022
Abstract: Oncogene activation during tumorigenesis promotes DNA replication stress (RS), which subsequently drives the formation of cancer-associated chromos... Read more »
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iDeal ChIP-qPCR
The leaf beetle Chelymorpha alternans propagates a plant pathogen i...
Published: August, 2022
Abstract: Many insects rely on microbial protection in the early stages of their development. However, in contrast to symbiont-mediated defense of eggs and y... Read more »
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Megaruptor
bESCs from cloned embryos do not retain transcriptomic or epigeneti...
Published: August, 2022
Abstract: Embryonic stem cells (ESC) indefinitely maintain the pluripotent state of the blastocyst epiblast. Stem cells are invaluable for studying developme... Read more »
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Antibody
A haplotype resolved chromosomal level avocado genome allows analys...
Published: August, 2022
Abstract: Avocado (Persea americana) is a member of the magnoliids, an early branching lineage of angiosperms that has high value globally with the fruit bei... Read more »
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Megaruptor
Histone lysine demethylase inhibition reprograms prostate cancermet...
Published: August, 2022
Abstract: OBJECTIVE: Aberrant activity of androgen receptor (AR) is the primary cause underlying development and progression of prostate cancer (PCa) and cas... Read more »
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Antibody Bioruptor Plus
The Arabidopsis APOLO and human UPAT sequence-unrelated longnoncodi...
Published: August, 2022
Abstract: BACKGROUND: RNA-DNA hybrid (R-loop)-associated long noncoding RNAs (lncRNAs), including the Arabidopsis lncRNA AUXIN-REGULATED PROMOTER LOOP (APOLO... Read more »
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Bioruptor Antibody
Histone H3K36me2 and H3K36me3 form a chromatin platform essentialfo...
Published: August, 2022
Abstract: Establishment of the DNA methylation landscape of mammalian oocytes, mediated by the DNMT3A-DNMT3L complex, is crucial for reproduction and develop... Read more »
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Antibody
Epigenetic remodeling of downstream enhancer regions is linked tose...
Published: August, 2022
Abstract: Interleukin (IL)-38, encoded by the IL1F10 gene, is a member of the IL-1 family of cytokines. IL-38 is constitutively expressed in epithelia in hea... Read more »
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Antibody iDeal ChIP-qPCR
A SOX2-engineered epigenetic silencer factor represses the glioblas...
Published: August, 2022
Abstract: Current therapies remain unsatisfactory in preventing the recurrence of glioblastoma multiforme (GBM), which leads to poor patient survival. By rat... Read more »
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MagMeDIP kit CUT&Tag
mTORC1 is required for epigenetic silencing during β-cell functiona...
Published: August, 2022
Abstract: OBJECTIVE: The mechanistic target of rapamycin comple×1 (mTORC1) is a key molecule that links nutrients, hormones, and growth factors to cell... Read more »
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MagMeDIP kit
Prolonged FOS activity disrupts a global myogenic transcriptionalpr...
Published: August, 2022
Abstract: BACKGROUND: The AP-1 transcription factor, FBJ osteosarcoma oncogene (FOS), is induced in adult muscle satellite cells (SCs) within hours following... Read more »
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Bioruptor Antibody iDeal ChIP-qPCR
Neutral sphingomyelinase 2 inhibition attenuates extracellular vesi...
Published: July, 2022
Abstract: People living with HIV (PLH) have significantly higher rates of cognitive impairment (CI) and major depressive disorder (MDD) versus the general po... Read more »
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D-Plex small RNA-seq
Large-scale manipulation of promoter DNA methylation revealscontext...
Published: July, 2022
Abstract: BACKGROUND: Cytosine DNA methylation is widely described as a transcriptional repressive mark with the capacity to silence promoters. Epigenome eng... Read more »
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Antibody
HOTAIR interacts with PRC2 complex regulating the regional preadipo...
Published: July, 2022
Abstract: Mechanisms governing regional human adipose tissue (AT) development remain undefined. Here, we show that the long non-coding RNA HOTAIR (HOX transc... Read more »
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Antibody
A novel, essential trans-splicing protein connects the nematode SL1...
Published: July, 2022
Abstract: Spliced leader trans-splicing is essential for gene expression in many eukaryotes. To elucidate the molecular mechanism of this process, we charact... Read more »
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D-Plex small RNA-seq
Interspecies effectors of a transgenerational memory of bacterial i...
Published: July, 2022
Abstract: The inheritance of memory is an adaptive trait. Microbes challenge the immunity of organisms and trigger behavioral adaptations that can be inherit... Read more »
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D-Plex small RNA-seq
X-linked myotubular myopathy is associated with epigenetic alterati...
Published: July, 2022
Abstract: X-linked myotubular myopathy (XLMTM) is a fatal neuromuscular disorder caused by loss of function mutations in MTM1. At present, there are no direc... Read more »
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Chromatin Shearing
The genome sequence of the hawthorn shieldbug, Acanthosomahaemorrho...
Published: July, 2022
Abstract: We present a genome assembly from an individual male Acanthosoma haemorrhoidale (hawthorn shieldbug; Arthropoda; Insecta; Hemiptera; Acanthosomatid... Read more »
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Megaruptor
Identification of Laportea bulbifera using the Complete Chloroplast...
Published: July, 2022
Abstract: Laportea bulbifera, a Miao medicine grown in karst areas, has exerts a unique curative effect on skin itching in the elderly, with an annual sales ... Read more »
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Megaruptor
The genome sequence of the dun-bar pinion, Cosmia trapezina(Linnaeu...
Published: July, 2022
Abstract: We present a genome assembly from an individual male Cosmia trapezina (dun-bar pinion; Arthropoda; Insecta; Lepidoptera; Noctuidae). The genome seq... Read more »
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Megaruptor
Genome-wide DNA hypermethylation opposes healing in chronic woundpa...
Published: July, 2022
Abstract: An extreme chronic wound tissue microenvironment causes epigenetic gene silencing. Unbiased whole-genome methylome was studied in the wound-edge (W... Read more »
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MethylCap
Oxford Nanopore R10.4 long-read sequencing enables the generation o...
Published: July, 2022
Abstract: Long-read Oxford Nanopore sequencing has democratized microbial genome sequencing and enables the recovery of highly contiguous microbial genomes f... Read more »
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Megaruptor
Embryonic heat conditioning in chicks induces transgenerationalheat...
Published: July, 2022
Abstract: The question of whether behavioral traits are heritable is under debate. An obstacle in demonstrating transgenerational inheritance in mammals orig... Read more »
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Antibody
Androgen-Induced MIG6 Regulates Phosphorylation ofRetinoblastoma Pr...
Published: July, 2022
Abstract: The bipolar androgen therapy (BAT) includes the treatment of prostate cancer (PCa) patients with supraphysiological androgen level (SAL). Interesti... Read more »
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iDeal ChIP-seq Kit for Transcription Factors ChIP Cross-link Gold
Epiblast inducers capture mouse trophectoderm stem cells in vitro a...
Published: July, 2022
Abstract: The embryo instructs the allocation of cell states to spatially regulate functions. In the blastocyst, patterning of trophoblast (TR) cells ensures... Read more »
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Antibody
Nox4 promotes endothelial differentiation through chromatin remodel...
Published: July, 2022
Abstract: RATIONALE: Nox4 is a constitutively active NADPH oxidase that constantly produces low levels of HO. Thereby, Nox4 contributes to cell homeostasis a... Read more »
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Antibody
Complete Genome Sequences of Multidrug-Resistant Campylobactercoli ...
Published: July, 2022
Abstract: Campylobacter coli is an important foodborne pathogen that can cause inflammation of the intestine and diarrhea in humans. The complete genomes, in... Read more »
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Megaruptor
High-Quality Genome Assembly of Nannochloris desiccata 2437 andIts ...
Published: July, 2022
Abstract: High-quality genome sequences were generated for the nonaxenic marine microalga Nannochloris desiccata UTEX 2437 and eight of its associated enviro... Read more »
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Megaruptor
Diverse Monogenic Subforms of Human Spermatogenic Failure
Published: July, 2022
Abstract: Non-obstructive azoospermia (NOA) is the most severe form of male infertility and typically incurable with current medicine. Due to the biological ... Read more »
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D-Plex small RNA-seq

イベント

  • EpiNantes 2024
    Nantes, France
    Sep 24-Sep 25, 2024
  • Nanopore Research Day Antwerp
    Antwerp, Belgium
    Sep 27, 2024
  • 10th Canadian Conference on Epigenetics
    Ontario, Canada
    Oct 1-Oct 4, 2024
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