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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Co-inhibition of ATM and ROCK synergistically improves cellprolifer...
Published: July, 2022
Abstract: The multifaceted nature of senescent cell cycle arrest necessitates the targeting of multiple factors arresting or promoting the cell cycle. We rep... Read more »
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iDeal ChIP-seq Kit for Transcription Factors
Spatially resolved epigenome-transcriptome co-profiling of mammalia...
Published: June, 2022
Abstract: Emerging spatial technologies including spatial transcriptomics and spatial epigenomics are becoming powerful tools for profiling cellular states i... Read more »
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Tagmentase CUT&Tag
A genome-wide screen reveals new regulators of the 2-cell-like cell...
Published: June, 2022
Abstract: In mammals, only the zygote and blastomeres of the early embryo are fully totipotent. This totipotency is mirrored in vitro by mouse "2-cell-like c... Read more »
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Newly added
Epigenomic analysis reveals a dynamic and context-specific macropha...
Published: June, 2022
Abstract: BACKGROUND: Chromatin states and enhancers associate gene expression, cell identity and disease. Here, we systematically delineate the acute innate... Read more »
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Antibody
Derailed peripheral circadian genes in polycystic ovary syndrome pa...
Published: June, 2022
Abstract: STUDY QUESTION: Do circadian genes exhibit an altered profile in peripheral blood mononuclear cells (PBMCs) of polycystic ovary syndrome (PCOS) pat... Read more »
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iDeal ChIP-seq Kit for Transcription Factors
Nuclear receptor RORγ inverse agonists/antagonists display tissue- ...
Published: June, 2022
Abstract: The nuclear receptor RORγ is a major driver of autoimmune diseases and certain types of cancer due to its aberrant function in T helper 17 (T... Read more »
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Antibody
Ultrasensitive Ribo-seq reveals translational landscapes during mam...
Published: June, 2022
Abstract: In mammals, translational control plays critical roles during oocyte-to-embryo transition (OET) when transcription ceases. However, the underlying ... Read more »
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D-Plex small RNA-seq
Detection of ovarian cancer using plasma cell-free DNA methylomes.
Published: June, 2022
Abstract: BACKGROUND: Ovarian cancer (OC) is a highly lethal gynecologic cancer, and it is hard to diagnose at an early stage. Clinically, there are no ovari... Read more »
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MagMeDIP kit
HISTONE DEACETYLASE 15 and MOS4-Associated Complex subunits3A/3B co...
Published: June, 2022
Abstract: Histone deacetylases (HDAs) play an important role in transcriptional regulation of multiple biological processes. In this study, we investigated t... Read more »
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Antibody
TBX2 acts as a potent transcriptional silencer of tumour suppressor...
Published: June, 2022
Abstract: Chromosome 17q23 amplification occurs in 20\% of primary breast tumours and is associated with poor outcome. The TBX2 gene is located on 17q23 and ... Read more »
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Microplex Library Preparation kit
Analysis of estrogen-regulated enhancer RNAs identifies a functiona...
Published: June, 2022
Abstract: To better understand the functions of non-coding enhancer RNAs (eRNAs), we annotated the estrogen-regulated eRNA transcriptome in estrogen receptor... Read more »
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CRISPR
A genome-wide screen reveals new regulators of the 2-cell-like cell...
Published: June, 2022
Abstract: In mammals, only the zygote and blastomeres of the early embryo are fully totipotent. This totipotency is mirrored in vitro by mouse "2-cell-like c... Read more »
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MagMeDIP kit IP-Star Compact
Long-read Oxford nanopore sequencing reveals a de novo case of comp...
Published: June, 2022
Abstract: BACKGROUND: Complex chromosomal rearrangements (CCRs) are associated with high reproductive risk, infertility, abnormalities in offspring, and recu... Read more »
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Megaruptor
NSUN2-mediated RNA mC modification modulates uveal melanoma cellpro...
Published: June, 2022
Abstract: RNA 5-methylcytosine (mC) is a widespread post-transcriptional modification involved in diverse biological processes through controlling RNA metabo... Read more »
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Antibody
Caffeine intake exerts dual genome-wide effects on hippocampal meta...
Published: June, 2022
Abstract: Caffeine is the most widely consumed psychoactive substance in the world. Strikingly, the molecular pathways engaged by its regular consumption rem... Read more »
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Antibody Microplex Library Preparation kit CUT&Tag
EHF is a novel regulator of cellular redox metabolism and predictsp...
Published: June, 2022
Abstract: Head and Neck Squamous Cell Carcinoma (HNSCC) is a heterogeneous disease with relatively high morbidity and mortality rates. The lack of effective ... Read more »
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Chromatin Shearing Antibody
Accumulation of endosymbiont genomes in an insect autosome followed...
Published: May, 2022
Abstract: Eukaryotic genomes can acquire bacterial DNA via lateral gene transfer (LGT). A prominent source of LGT is Wolbachia, a widespread endosymbiont of ... Read more »
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Megaruptor
DNA Hypermethylation and a Specific Methylation Spectrum on theX Ch...
Published: May, 2022
Abstract: The molecular genetic mechanism of Turner syndrome (TS) still leaves much to be discovered. Methods: TS (45X0) patients and age-matched controls (4... Read more »
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Megaruptor
Development of a quantitative methylation-specific droplet digital ...
Published: May, 2022
Abstract: OBJECTIVE: The detection and monitoring of DNA methylation status in circulating tumor cell DNA (ctDNA) provides critical insights into cancer diag... Read more »
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Premium Bisulfite Kit
DNA methylation may affect beef tenderness through signal transduct...
Published: May, 2022
Abstract: BACKGROUND: Beef tenderness is a complex trait of economic importance for the beef industry. Understanding the epigenetic mechanisms underlying thi... Read more »
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Premium RRBS Kit DNA Methylation Profiling (RRBS Service)
Cell-wall damage activates DOF transcription factors to promote wou...
Published: May, 2022
Abstract: Wound healing is a fundamental property of plants and animals that requires recognition of cellular damage to initiate regeneration. In plants, wou... Read more »
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IPure kit
TRF2 cooperates with CTCF for controlling the oncomiR-193b-3p incol...
Published: May, 2022
Abstract: The Telomeric Repeat binding Factor 2 (TRF2), a key protein involved in telomere integrity, is over-expressed in several human cancers and promotes... Read more »
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Antibody
GATA6 is predicted to regulate DNA methylation in an in vitro model...
Published: May, 2022
Abstract: Hepatocytes are the dominant cell type in the human liver, with functions in metabolism, detoxification, and producing secreted proteins. Although ... Read more »
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IP-Star Compact iDeal ChIP-seq Kit for Transcription Factors ChIPmentation
Developmental mRNA mC landscape and regulatory innovations of massi...
Published: May, 2022
Abstract: mC is one of the longest-known RNA modifications, however, its developmental dynamics, functions, and evolution in mRNAs remain largely unknown. He... Read more »
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Antibody
Heat stress during grain filling regulates seed germination through...
Published: May, 2022
Abstract: KEY MESSAGE: Alterations in DNA methylation levels of ROS, GA and ABA related gene promoters cause transcriptional changes upon imbibition to induc... Read more »
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MagMeDIP kit
AP4 suppresses DNA damage, chromosomal instability and senescence v...
Published: May, 2022
Abstract: Background AP4 (TFAP4) encodes a basic helix-loop-helix leucine zipper (bHLH-LZ) transcription factor and is a direct target gene of the oncogenic ... Read more »
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iDeal ChIP-qPCR
Hexokinase 2 is a transcriptional target and a positive modulator o...
Published: May, 2022
Abstract: The aryl hydrocarbon receptor (AHR) regulates the expression of numerous genes in response to activation by agonists including xenobiotics. Althoug... Read more »
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Bioruptor MagMeDIP kit
HIRA supports hepatitis B virus minichromosome establishment andtra...
Published: May, 2022
Abstract: BACKGROUND \& AIMS: Upon Hepatitis B virus (HBV) infection, partially double stranded viral DNA converts into a covalently-closed-circular chro... Read more »
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Antibody
Novel role of UHRF1 in the epigenetic repression of the latent HIV-1.
Published: May, 2022
Abstract: BACKGROUND: The multiplicity, heterogeneity, and dynamic nature of human immunodeficiency virus type-1 (HIV-1) latency mechanisms are reflected in ... Read more »
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Antibody
Translation is a key determinant controlling the fate of cytoplasmi...
Published: May, 2022
Abstract: Despite predicted to lack coding potential, cytoplasmic long non-coding (lnc)RNAs can associate with ribosomes, resulting in some cases into the pr... Read more »
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D-Plex small RNA-seq

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  • FASEB Biological Methylation: Fundamental Mechanisms
    Porto, Portugal
    Jul 28-Aug 1, 2024
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