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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Single-cell multi-omics, spatial transcriptomics and systematic per...
Published: September, 2024
Abstract: Cranial neural crest (NC) cells, which can migrate, adopt multiple fates, and form most of the craniofacial skeleton, are an excellent model for st... Read more »
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Antibody True MicroChIP kit
Optimization of ribosome profiling in plants including structural a...
Published: September, 2024
Abstract: Background Ribosome profiling (or Ribo-seq) is a technique that provides genome-wide information on the translational landscape (translatome). Acr... Read more »
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D-Plex small RNA-seq
Systematic prioritization of functional variants and effector genes...
Published: September, 2024
Abstract: Genome-wide association studies of colorectal cancer (CRC) have identified 170 autosomal risk loci. However, for most of these, the functional vari... Read more »
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Antibody
An ERRα-ZEB1 transcriptional signature predicts survival in triple-...
Published: September, 2024
Abstract: Background. Transcription factors (TFs) act together with co-regulators to modulate the expression of their target genes, which eventually dictate... Read more »
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iDeal ChIP-seq Kit for Transcription Factors
Auto-expansion of in vivo HDAd-transduced hematopoietic stem cells ...
Published: September, 2024
Abstract: We developed an in vivo hematopoietic stem cell (HSC) gene therapy approach that does not require cell transplantation. To achieve t... Read more »
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Tagmentase
Nuclear lamin A/C phosphorylation by loss of androgen receptor lead...
Published: September, 2024
Abstract: Alterations in nuclear structure and function are hallmarks of cancer cells. Little is known about these changes in Cancer-Associated Fibroblasts (... Read more »
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iDeal ChIP-seq Kit for Transcription Factors Tagmentase
A critical role for HNF4α in polymicrobial sepsis-associated metabo...
Published: September, 2024
Abstract: In sepsis, limited food intake and increased energy expenditure induce a starvation response, which is compromised by a quick decline in the expres... Read more »
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Tagmentase
Bivalent chromatin accommodates survivin and BRG1/SWI complex to ac...
Published: September, 2024
Abstract: Background Bivalent regions of chromatin (BvCR) are characterized by trimethylated lysine 4 (H3K4me3) and lysine 27 on histone H3 (H3K27me3)... Read more »
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Antibody
Triphenyl Phosphate Alters Methyltransferase Expression and Induces...
Published: August, 2024
Abstract: Emerging environmental contaminants, organophosphate flame retardants (OPFRs), pose significant threats to ecosystems and human health. Despite num... Read more »
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Premium RRBS Kit
An atlas of the human liver diurnal transcriptome and its perturbat...
Published: August, 2024
Abstract: Chronic liver disease and cancer are global health challenges. The role of the circadian clock as a regulator of liver physiology and disease is we... Read more »
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Microplex Library Preparation kit
A PRE loop at the dac locus acts as a topological chromatin structu...
Published: August, 2024
Abstract: Three-dimensional (3D) genome folding has a fundamental role in the regulation of developmental genes by facilitating or constraining chromatin int... Read more »
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ChIP-qPCR
Temporal and spatial niche partitioning in a retrotransposon commun...
Published: August, 2024
Abstract: Transposable elements (TEs), widespread genetic parasites, pose potential threats to the stability of their host genomes. Hence, the interactions o... Read more »
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ATAC-seq
Inherited defects of piRNA biogenesis cause transposon de-repressio...
Published: August, 2024
Abstract: piRNAs are crucial for transposon silencing, germ cell maturation, and fertility in male mice. Here, we report on the genetic landscape of piRNA dy... Read more »
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D-Plex small RNA-seq
Detection of genome structural variation in normal cells and tissue...
Published: August, 2024
Abstract: Detecting somatic mutations in normal cells and tissues is notoriously challenging due to their low abundance, orders of magnitude below the sequen... Read more »
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Tagmentase
Association between TNF-α, cortisol levels, and exposure to PM10 an...
Published: August, 2024
Abstract: Purpose The most harmful atmospheric pollutant for human health is particulate matter (PM). We analyzed the correlation between short-term lag exp... Read more »
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MagMeDIP kit
Human induced pluripotent stem cells for live cell cycle monitoring...
Published: August, 2024
Abstract: The fluorescence ubiquitination cell cycle inhibitor (FUCCI) has been introduced to monitor cell cycle activity in living cells, including human in... Read more »
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Antibody CRISPR
LL37/self-DNA complexes mediate monocyte reprogramming
Published: August, 2024
Abstract: LL37 alone and in complex with self-DNA triggers inflammatory responses in myeloid cells and plays a crucial role in the development of systemic au... Read more »
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Antibody
Innate immune training restores pro-reparative myeloid functions to...
Published: July, 2024
Abstract: The reduced ability of the central nervous system to regenerate with increasing age limits functional recovery following demyelinating injury. Prev... Read more »
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Antibody iDeal ChIP-seq Kit for Histones Chromatin Profiling (ChIP-seq) Services
Biochemical role of FOXM1-dependent histone linker H1B in human epi...
Published: July, 2024
Abstract: Epidermal stem cells orchestrate epidermal renewal and timely wound repair through a tight regulation of self-renewal, proliferation, and different... Read more »
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iDeal ChIP-seq Kit for Transcription Factors
A multiomic atlas of the aging hippocampus reveals molecular change...
Published: July, 2024
Abstract: Aging involves the deterioration of organismal function, leading to the emergence of multiple pathologies. Environmental stimuli, including lifesty... Read more »
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Antibody Microplex Library Preparation kit iDeal ChIP-seq Kit for Histones
Loss of tumor suppressors promotes inflammatory tumor microenvironm...
Published: July, 2024
Abstract: Low response rate, treatment relapse, and resistance remain key challenges for cancer treatment with immune checkpoint blockade (ICB). Here we repo... Read more »
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Antibody CRISPR
Epigenetic alterations affecting hematopoietic regulatory networks ...
Published: July, 2024
Abstract: Leukemias with ambiguous lineage comprise several loosely defined entities, often without a clear mechanistic basis. Here, we extensively profile t... Read more »
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Antibody Microplex Library Preparation kit
The landscape of RNA-chromatin interaction reveals small non-coding...
Published: June, 2024
Abstract: RNA constitutes a large fraction of chromatin. Spatial distribution and functional relevance of most of RNA-chromatin interactions remain unknown. ... Read more »
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Bioruptor Antibody iDeal ChIP-seq Kit for Transcription Factors iDeal ChIP-seq Kit for Histones
Epigenomic signatures of sarcomatoid differentiation to guide the t...
Published: June, 2024
Abstract: Renal cell carcinoma with sarcomatoid differentiation (sRCC) is associated with poor survival and a heightened response to immune checkpoint inhibi... Read more »
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MagMeDIP kit Antibody IPure kit
KRAS promotes GLI2-dependent transcription during pancreatic carcin...
Published: June, 2024
Abstract: Aberrant activation of GLI transcription factors has been implicated in the pathogenesis of different tumor types including pancreatic ductal adeno... Read more »
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Antibody
Detecting small cell transformation in patients with advanced EGFR ...
Published: June, 2024
Abstract: Purpose: Histologic transformation to small cell lung cancer (SCLC) is a mechanism of treatment resistance in patients with advanced oncogene-drive... Read more »
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MagMeDIP kit IPure kit
Single-cell epigenomic reconstruction of developmental trajectories...
Published: June, 2024
Abstract: Cell fate progression of pluripotent progenitors is strictly regulated, resulting in high human cell diversity. Epigenetic modifications also orche... Read more »
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Bioruptor Antibody
Prostate cancer detection through unbiased capture of methylated ce...
Published: June, 2024
Abstract: Prostate cancer screening using prostate-specific antigen (PSA) has been shown to reduce mortality but with substantial overdiagnosis, leading to u... Read more »
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MagMeDIP kit IPure kit
The ETO2 transcriptional cofactor maintains acute leukemia by drivi...
Published: June, 2024
Abstract: Transcriptional cofactors of the ETO family are recurrent fusion partners in acute leukemia. We characterized the ETO2 regulome by integrating tran... Read more »
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IPure kit
Master corepressor inactivation through multivalent SLiM-induced po...
Published: June, 2024
Abstract: While the elucidation of regulatory mechanisms of folded proteins is facilitated due to their amenability to high-resolution structural characteriz... Read more »
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Antibody

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