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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Prostate cancer detection through unbiased capture of methylated ce...
Published: June, 2024
Abstract: Prostate cancer screening using prostate-specific antigen (PSA) has been shown to reduce mortality but with substantial overdiagnosis, leading to u... Read more »
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MagMeDIP kit IPure kit
The ETO2 transcriptional cofactor maintains acute leukemia by drivi...
Published: June, 2024
Abstract: Transcriptional cofactors of the ETO family are recurrent fusion partners in acute leukemia. We characterized the ETO2 regulome by integrating tran... Read more »
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IPure kit
Master corepressor inactivation through multivalent SLiM-induced po...
Published: June, 2024
Abstract: While the elucidation of regulatory mechanisms of folded proteins is facilitated due to their amenability to high-resolution structural characteriz... Read more »
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Antibody
Master corepressor inactivation through multivalent SLiM-induced po...
Published: June, 2024
Abstract: While the elucidation of regulatory mechanisms of folded proteins is facilitated due to their amenability to high-resolution structural characteriz... Read more »
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Antibody
Brassica rapa CURLY LEAF is a major H3K27 methyltransferase regulat...
Published: June, 2024
Abstract: Main conclusion In Brassica rapa, the epigenetic modifier BraA.CLF orchestrates flowering by modulating H3K27me3 levels at the floral integra... Read more »
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Antibody
Disease related changes in ATAC-seq of iPSC-derived motor neuron li...
Published: May, 2024
Abstract: Amyotrophic Lateral Sclerosis (ALS), like many other neurodegenerative diseases, is highly heritable, but with only a small fraction of cases expla... Read more »
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ATAC-seq
Positive and negative feedback regulation of the TGF-β1 explains tw...
Published: April, 2024
Abstract: During aging, skin homeostasis is essential for maintaining appearance, as well as biological defense of the human body. In this study, we identi... Read more »
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iDeal ChIP-seq Kit for Histones
Cis-regulatory interfaces reveal the molecular mechanisms underlyin...
Published: April, 2024
Abstract: Tissue-specific gene expression is fundamental in development and evolution, and is mediated by transcription factors and by the cis-regulator... Read more »
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CRISPR
Systematic mapping of TF-mediated cell fate changes by a pooled ind...
Published: April, 2024
Abstract: Transcriptional regulation controls cellular functions through interactions between transcription factors (TFs) and their chromosomal targets. Howe... Read more »
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ATAC-seq
Differential DNA methylation in iPSC-derived dopaminergic neurons: ...
Published: April, 2024
Abstract: Introduction A microdeletion including the SNORD116 gene (SNORD116 MD) has been shown to drive the Prader-Willi syndrome (PWS) feat... Read more »
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Premium RRBS Kit
Epigenetics and suicide: investigating altered H3K14ac unveiled dif...
Published: March, 2024
Abstract: Background: Environmental factors make an important contribution to suicide. Histone tails are prone to different modifications, leading to ch... Read more »
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ChIPmentation
TET2 Deficiency Increases the Competitive Advantage of Hematopoieti...
Published: March, 2024
Abstract: Ten-Eleven Translocation-2 (TET2) mutations drive the expansion of mutant hematopoietic stem cells (HSCs) in clonal hematopoiesis (CH). However, th... Read more »
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Chromatin Shearing
Integrative network analysis of differentially methylated regions t...
Published: March, 2024
Abstract: Integrative network analysis (INA) is important for identifying gene modules or epigenetically regulated molecular pathways in diseases. This study... Read more »
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Infinium Human MethylationEPIC Array Service
High-throughput sequencing of insect specimens with sub-optimal DNA...
Published: March, 2024
Abstract: Entomological sampling and storage conditions often prioritise efficiency, practicality and conservation of morphological characteristics, and may ... Read more »
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Tagmentase
Technical considerations for cost-effective transposon directed ins...
Published: March, 2024
Abstract: Transposon directed insertion-site sequencing (TraDIS), a variant of transposon insertion sequencing commonly known as Tn-Seq, is a high-throughput... Read more »
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Tagmentase
Protocol to isolate nuclei from Chlamydomonas reinhardtii for ATAC ...
Published: March, 2024
Abstract: Highlights Optimized isolation of nuclei from the green model alga Chlamydomonas reinhardtii Tag-free isolation from both cell-w... Read more »
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ATAC-seq
Chromatin profiling reveals TFAP4 as a critical transcriptional reg...
Published: March, 2024
Abstract: Background Satellite cells are myogenic precursor cells in adult skeletal muscle and play a crucial role in skeletal muscle regeneration, maintena... Read more »
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Antibody iDeal ChIP-seq Kit for Histones
On the identification of differentially-active transcription factor...
Published: March, 2024
Abstract: ATAC-seq has emerged as a rich epigenome profiling technique, and is commonly used to identify Transcription Factors (TFs) underlying given phenome... Read more »
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Tagmentase
SURVIVIN IN SYNERGY WITH BAF/SWI COMPLEX BINDS BIVALENT CHROMATIN R...
Published: March, 2024
Abstract: This study explores a regulatory role of oncoprotein survivin on the bivalent regions of chromatin (BvCR) characterized by concomitant deposition o... Read more »
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Antibody
Focal cortical dysplasia type II-dependent maladaptive myelination ...
Published: March, 2024
Abstract: Focal cortical dysplasias (FCDs) are local malformations of the human neocortex and a leading cause of intractable epilepsy. FCDs are classified in... Read more »
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IPure kit iDeal ChIP-seq Kit for Transcription Factors
Pervasive translation of Xrn1-sensitive unstable long non-coding RN...
Published: March, 2024
Abstract: Despite being predicted to lack coding potential, cytoplasmic long non-coding (lnc)RNAs can associate with ribosomes. However, the landscape and bi... Read more »
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D-Plex small RNA-seq
A Pre-Leukemic DNA Methylation Signature in Healthy Individuals at ...
Published: March, 2024
Abstract: Purpose: DNA methylation alterations are widespread in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS), some of which appear to hav... Read more »
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MagMeDIP kit
Making Biological Ageing Clocks Personal
Published: February, 2024
Abstract: Background Age is the most important risk factor for the majority of human diseases. Addressing the impact of age-related diseases has becom... Read more »
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Infinium Human MethylationEPIC Array Service
Interplay between coding and non-coding regulation drives the Arabi...
Published: February, 2024
Abstract: Translation of seed stored mRNAs is essential to trigger germination. However, when RNAPII re-engages RNA synthesis during the seed-to-seedling tra... Read more »
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ATAC-seq
Cellular reprogramming in vivo initiated by SOX4 pioneer factor act...
Published: February, 2024
Abstract: Tissue damage elicits cell fate switching through a process called metaplasia, but how the starting cell fate is silenced and the new cell fate is ... Read more »
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Tagmentase
MYB/LINC00092 regulatory axis promotes the progression of papillary...
Published: February, 2024
Abstract: Introduction:Thyroid carcinoma is the most frequent malignancy in different endocrine-related tumours. In this study, we demonstrated a long non-co... Read more »
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iDeal ChIP-qPCR
Plasticity-induced repression of Irf6 underlies acquired resistance...
Published: February, 2024
Abstract: Acquired resistance to immunotherapy remains a critical yet incompletely understood biological mechanism. Here, using a mouse model of pancreatic d... Read more »
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Tagmentase
Multiomics uncovers the epigenomic and transcriptomic response to v...
Published: February, 2024
Abstract: Uncovering the epigenomic regulation of immune responses is essential for a comprehensive understanding of host defence mechanisms but remains poor... Read more »
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Microplex Library Preparation kit ChIPmentation
Neurofibromin 1 controls metabolic balance and Notch-dependent quie...
Published: February, 2024
Abstract: Patients affected by neurofibromatosis type 1 (NF1) frequently show muscle weakness with unknown etiology. Here we show that, in mice, Neurofibromi... Read more »
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MagMeDIP kit
Inhibition of Aurora kinase induces endogenous retroelements to ind...
Published: February, 2024
Abstract: Type I interferon signaling is a crucial component of anti-viral immunity that has been linked to promoting the efficacy of some chemotherapeutic d... Read more »
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Infinium Human MethylationEPIC Array Service

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