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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Patho-transcriptomic analysis of invasive mucinous adenocarcinoma o...
Published: June, 2024
Abstract: Background Invasive mucinous adenocarcinoma (IMA) comprises ∼5% of lung adenocarcinoma. There is no effective therapy for IMA when surgi... Read more »
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ATAC-seq
Brassica rapa CURLY LEAF is a major H3K27 methyltransferase regulat...
Published: June, 2024
Abstract: Main conclusion In Brassica rapa, the epigenetic modifier BraA.CLF orchestrates flowering by modulating H3K27me3 levels at the floral integra... Read more »
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Antibody
Clock-dependent chromatin accessibility rhythms regulate circadian ...
Published: May, 2024
Abstract: Chromatin organization plays a crucial role in gene regulation by controlling the accessibility of DNA to transcription machinery. While significan... Read more »
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Tagmentase
Disease related changes in ATAC-seq of iPSC-derived motor neuron li...
Published: May, 2024
Abstract: Amyotrophic Lateral Sclerosis (ALS), like many other neurodegenerative diseases, is highly heritable, but with only a small fraction of cases expla... Read more »
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ATAC-seq
Transient loss of Polycomb components induces an epigenetic cancer ...
Published: April, 2024
Abstract: Although cancer initiation and progression are generally associated with the accumulation of somatic mutations1,2, substantial epigenomic alteratio... Read more »
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ATAC-seq
PBK/TOPK mediates Ikaros, Aiolos and CTCF displacement from mitotic...
Published: April, 2024
Abstract: PBK/TOPK is a mitotic kinase implicated in haematological and non-haematological cancers. Here we show that the key haemopoietic regulators Ikaros ... Read more »
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Tagmentase
Widespread impact of nucleosome remodelers on transcription at cis-...
Published: April, 2024
Abstract: Nucleosome remodeling complexes and other regulatory factors work in concert to build a chromatin environment that directs the expression of a dist... Read more »
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Tagmentase
Positive and negative feedback regulation of the TGF-β1 explains tw...
Published: April, 2024
Abstract: During aging, skin homeostasis is essential for maintaining appearance, as well as biological defense of the human body. In this study, we identi... Read more »
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iDeal ChIP-seq Kit for Histones
Cis-regulatory interfaces reveal the molecular mechanisms underlyin...
Published: April, 2024
Abstract: Tissue-specific gene expression is fundamental in development and evolution, and is mediated by transcription factors and by the cis-regulator... Read more »
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CRISPR
Systematic mapping of TF-mediated cell fate changes by a pooled ind...
Published: April, 2024
Abstract: Transcriptional regulation controls cellular functions through interactions between transcription factors (TFs) and their chromosomal targets. Howe... Read more »
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ATAC-seq
Differential DNA methylation in iPSC-derived dopaminergic neurons: ...
Published: April, 2024
Abstract: Introduction A microdeletion including the SNORD116 gene (SNORD116 MD) has been shown to drive the Prader-Willi syndrome (PWS) feat... Read more »
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Premium RRBS Kit
Epigenetics and suicide: investigating altered H3K14ac unveiled dif...
Published: March, 2024
Abstract: Background: Environmental factors make an important contribution to suicide. Histone tails are prone to different modifications, leading to ch... Read more »
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ChIPmentation
TET2 Deficiency Increases the Competitive Advantage of Hematopoieti...
Published: March, 2024
Abstract: Ten-Eleven Translocation-2 (TET2) mutations drive the expansion of mutant hematopoietic stem cells (HSCs) in clonal hematopoiesis (CH). However, th... Read more »
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Chromatin Shearing
Integrative network analysis of differentially methylated regions t...
Published: March, 2024
Abstract: Integrative network analysis (INA) is important for identifying gene modules or epigenetically regulated molecular pathways in diseases. This study... Read more »
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Infinium Human MethylationEPIC Array Service
High-throughput sequencing of insect specimens with sub-optimal DNA...
Published: March, 2024
Abstract: Entomological sampling and storage conditions often prioritise efficiency, practicality and conservation of morphological characteristics, and may ... Read more »
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Tagmentase
Technical considerations for cost-effective transposon directed ins...
Published: March, 2024
Abstract: Transposon directed insertion-site sequencing (TraDIS), a variant of transposon insertion sequencing commonly known as Tn-Seq, is a high-throughput... Read more »
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Tagmentase
MED1 IDR acetylation reorganizes the transcription preinitiation co...
Published: March, 2024
Abstract: With our current appreciation of the complexity of eukaryotic transcription, whose dysregulation drives diseases including cancer, it is becoming a... Read more »
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Tagmentase
Protocol to isolate nuclei from Chlamydomonas reinhardtii for ATAC ...
Published: March, 2024
Abstract: Highlights Optimized isolation of nuclei from the green model alga Chlamydomonas reinhardtii Tag-free isolation from both cell-w... Read more »
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ATAC-seq
EP300/CREBBP acetyltransferase inhibition limits steroid receptor a...
Published: March, 2024
Abstract: The androgen receptor (AR) is a primary target for treating prostate cancer (PCa), forming the bedrock of its clinical management. Despite their ef... Read more »
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Tagmentase
Chromatin profiling reveals TFAP4 as a critical transcriptional reg...
Published: March, 2024
Abstract: Background Satellite cells are myogenic precursor cells in adult skeletal muscle and play a crucial role in skeletal muscle regeneration, maintena... Read more »
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Antibody iDeal ChIP-seq Kit for Histones
On the identification of differentially-active transcription factor...
Published: March, 2024
Abstract: ATAC-seq has emerged as a rich epigenome profiling technique, and is commonly used to identify Transcription Factors (TFs) underlying given phenome... Read more »
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Tagmentase
SURVIVIN IN SYNERGY WITH BAF/SWI COMPLEX BINDS BIVALENT CHROMATIN R...
Published: March, 2024
Abstract: This study explores a regulatory role of oncoprotein survivin on the bivalent regions of chromatin (BvCR) characterized by concomitant deposition o... Read more »
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Antibody
Focal cortical dysplasia type II-dependent maladaptive myelination ...
Published: March, 2024
Abstract: Focal cortical dysplasias (FCDs) are local malformations of the human neocortex and a leading cause of intractable epilepsy. FCDs are classified in... Read more »
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IPure kit iDeal ChIP-seq Kit for Transcription Factors
Pervasive translation of Xrn1-sensitive unstable long non-coding RN...
Published: March, 2024
Abstract: Despite being predicted to lack coding potential, cytoplasmic long non-coding (lnc)RNAs can associate with ribosomes. However, the landscape and bi... Read more »
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D-Plex small RNA-seq
A Pre-Leukemic DNA Methylation Signature in Healthy Individuals at ...
Published: March, 2024
Abstract: Purpose: DNA methylation alterations are widespread in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS), some of which appear to hav... Read more »
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MagMeDIP kit
Making Biological Ageing Clocks Personal
Published: February, 2024
Abstract: Background Age is the most important risk factor for the majority of human diseases. Addressing the impact of age-related diseases has becom... Read more »
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Infinium Human MethylationEPIC Array Service
Interplay between coding and non-coding regulation drives the Arabi...
Published: February, 2024
Abstract: Translation of seed stored mRNAs is essential to trigger germination. However, when RNAPII re-engages RNA synthesis during the seed-to-seedling tra... Read more »
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ATAC-seq
Cellular reprogramming in vivo initiated by SOX4 pioneer factor act...
Published: February, 2024
Abstract: Tissue damage elicits cell fate switching through a process called metaplasia, but how the starting cell fate is silenced and the new cell fate is ... Read more »
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Tagmentase
MYB/LINC00092 regulatory axis promotes the progression of papillary...
Published: February, 2024
Abstract: Introduction:Thyroid carcinoma is the most frequent malignancy in different endocrine-related tumours. In this study, we demonstrated a long non-co... Read more »
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iDeal ChIP-qPCR
Plasticity-induced repression of Irf6 underlies acquired resistance...
Published: February, 2024
Abstract: Acquired resistance to immunotherapy remains a critical yet incompletely understood biological mechanism. Here, using a mouse model of pancreatic d... Read more »
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Tagmentase

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  • Pacbio PRISM
    Danang, Vietnam
    Apr 14-Apr 16, 2025
  • American Association of Cancer Research (AACR)
    Chicago (IL), USA
    Apr 25-Apr 30, 2025
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