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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Endogenous retroviruses are a source of enhancers with oncogenic po...
Published: April, 2020
Abstract: Acute myeloid leukemia (AML) is a highly aggressive hematopoietic malignancy, defined by a series of genetic and epigenetic alterations, which resu... Read more »
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Antibody
TET-Mediated Hypermethylation Primes SDH-Deficient Cells for HIF2α-...
Published: March, 2020
Abstract: Loss-of-function mutations in the SDHB subunit of succinate dehydrogenase predispose patients to aggressive tumors characterized by pseudohypo... Read more »
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MagMeDIP kit Antibody iDeal ChIP-qPCR
CRISPR-based gene knockout screens reveal deubiquitinases involved ...
Published: March, 2020
Abstract: The major barrier to a HIV-1 cure is the persistence of latent genomes despite treatment with antiretrovirals. To investigate host factors which pr... Read more »
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Antibody CRISPR
Differential modulation of the androgen receptor for prostate cance...
Published: March, 2020
Abstract: Androgen receptor (AR) action is a hallmark of prostate cancer (PCa) with androgen deprivation being standard therapy. Yet, resistance arises and a... Read more »
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Antibody IPure kit
High density of unrepaired genomic ribonucleotides leads to Topoiso...
Published: March, 2020
Abstract: Cellular levels of ribonucleoside triphosphates (rNTPs) are much higher than those of deoxyribonucleoside triphosphates (dNTPs), thereby influencin... Read more »
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Antibody
Multi-omic analysis of gametogenesis reveals a novel signature at t...
Published: March, 2020
Abstract: Epigenetic regulation of gene expression is tightly controlled by the dynamic modification of histones by chemical groups, the diversity of which h... Read more »
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IP-Star Compact Microplex Library Preparation kit iDeal ChIP-seq Kit for Histones Chromatin Profiling (ChIP-seq) Services
Alu retrotransposons modulate Nanog expression through dynamic chan...
Published: March, 2020
Abstract: Transcriptional repression of Nanog is an important hallmark of stem cell differentiation. Chromatin modifications have been linked to the epigenet... Read more »
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Antibody
Anti-adipogenic signals at the onset of obesity-related inflammatio...
Published: March, 2020
Abstract: Chronic inflammation that affects primarily metabolic organs, such as white adipose tissue (WAT), is considered as a major cause of human obesity-a... Read more »
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Microplex Library Preparation kit
LXR Activation Induces a Proinflammatory Trained Innate Immunity-Ph...
Published: March, 2020
Abstract: The concept of trained innate immunity describes a long-term proinflammatory memory in innate immune cells. Trained innate immunity is regulated th... Read more »
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Antibody
LY75 Ablation Mediates Mesenchymal-Epithelial Transition (MET) in E...
Published: March, 2020
Abstract: Growing evidence demonstrates that epithelial-mesenchymal transition (EMT) plays an important role in epithelial ovarian cancer (EOC) progression a... Read more »
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DNA Methylation Profiling (RRBS Service)
CDK7 Inhibition is Effective in all the Subtypes of Breast Cancer: ...
Published: March, 2020
Abstract: CDK7, a transcriptional cyclin-dependent kinase, is emerging as a novel cancer target. Triple-negative breast cancers (TNBC) but not estrogen recep... Read more »
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Antibody
Genome-wide DNA Methylation Analysis of Mantle Edge and Mantle Cent...
Published: March, 2020
Abstract: DNA methylation is a type of epigenetic modification that alters gene expression without changing the DNA sequence and mediates some cases of pheno... Read more »
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MagMeDIP kit
Dnmt3a and Dnmt3b-Decommissioned Fetal Enhancers are Linked to Kidn...
Published: March, 2020
Abstract: BACKGROUND: Cytosine methylation is an epigenetic mark that dictates cell fate and response to stimuli. The timing and establishment of methylation... Read more »
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Premium RRBS Kit
ChromID identifies the protein interactome at chromatin marks.
Published: March, 2020
Abstract: Chromatin modifications regulate genome function by recruiting proteins to the genome. However, the protein composition at distinct chromatin modif... Read more »
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Antibody
Human cardiac fibrosis-on-a-chip model recapitulates disease hallma...
Published: March, 2020
Abstract: While interstitial fibrosis plays a significant role in heart failure, our understanding of disease progression in humans is limited. To address th... Read more »
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CATS
HDAC3 functions as a positive regulator in Notch signal transduction.
Published: February, 2020
Abstract: Aberrant Notch signaling plays a pivotal role in T-cell acute lymphoblastic leukemia (T-ALL) and chronic lymphocytic leukemia (CLL). Amplitude and ... Read more »
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Antibody Microplex Library Preparation kit
A MORC-driven transcriptional switch controls Toxoplasma developmen...
Published: February, 2020
Abstract: Toxoplasma gondii has a complex life cycle that is typified by asexual development that takes place in vertebrates, and sexual reproduction, which ... Read more »
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Antibody IPure kit iDeal ChIP-seq Kit for Histones Beads
Transferrin Receptor 1 Regulates Thermogenic Capacity and Cell Fate...
Published: February, 2020
Abstract: Iron homeostasis is essential for maintaining cellular function in a wide range of cell types. However, whether iron affects the thermogenic proper... Read more »
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Antibody True MicroChIP kit
Recombination may occur in the absence of transcription in the immu...
Published: February, 2020
Abstract: Developing B cells undergo V(D)J recombination to generate a vast repertoire of Ig molecules. V(D)J recombination is initiated by the RAG1/RAG2 com... Read more »
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Antibody Premium Bisulfite Kit
Alteration of CTCF-associated chromatin neighborhood inhibits TAL1-...
Published: February, 2020
Abstract: Aberrant activation of the TAL1 is associated with up to 60% of T-ALL cases and is involved in CTCF-mediated genome organization within the TAL1 lo... Read more »
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Antibody
DNA Methylation Editing by CRISPR-guided Excision of 5-Methylcytosine.
Published: February, 2020
Abstract: Tools for actively targeted DNA demethylation are required to increase our knowledge about regulation and specific functions of this important epig... Read more »
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Antibody CRISPR
STAT Signaling Modifies Ascl1 Chromatin Binding and Limits Neural R...
Published: February, 2020
Abstract: Müller glia (MG) serve as sources for retinal regeneration in non-mammalian vertebrates. We find that this process can be induced in mous... Read more »
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LowCell ChIP kit
LncRNA np_5318 promotes renal ischemia‑reperfusion injury through t...
Published: February, 2020
Abstract: Long noncoding (Lnc)RNA np_5318 has been proved to be involved in renal injury, while its functionality in renal ischemia‑reperfusion (I/R) injury ... Read more »
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iDeal ChIP-seq Kit for Transcription Factors
Widespread loss of the silencing epigenetic mark H3K9me3 in astrocy...
Published: February, 2020
Abstract: BACKGROUND: Hexanucleotide repeat expansions of the GC motif in a non-coding region of the C9ORF72 gene are the most common genetic cause of amyotr... Read more »
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Antibody
Rheumatoid Arthritis Patients, Both Newly Diagnosed and Methotrexat...
Published: February, 2020
Abstract: Rheumatoid arthritis (RA) is a chronic autoimmune disease that causes pain and swelling of multiple joints in the body. The underlying disease mech... Read more »
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Premium RRBS Kit
Seviteronel, a Novel CYP17 Lyase Inhibitor and Androgen Receptor An...
Published: February, 2020
Abstract: Increased rates of locoregional recurrence (LR) have been observed in triple negative breast cancer (TNBC) despite multimodality therapy, including... Read more »
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HighCell ChIP kit IPure kit
MYCN amplification and ATRX mutations are incompatible in neuroblas...
Published: February, 2020
Abstract: Aggressive cancers often have activating mutations in growth-controlling oncogenes and inactivating mutations in tumor-suppressor genes. In neurobl... Read more »
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iDeal ChIP-seq Kit for Histones
Inhibition of methyltransferase activity of enhancer of zeste 2 lea...
Published: February, 2020
Abstract: BACKGROUND: Recent studies indicate that exposure to environmental chemicals may increase susceptibility to developing metabolic diseases. This sus... Read more »
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Antibody
REDOX RESPONSIVE TRANSCRIPTION FACTOR1 (RRFT1) is involved in extra...
Published: February, 2020
Abstract: Extracellular ATP (eATP) is an apoplastic signaling molecule that plays essential roles in the growth and development of plants. Arabidopsis seedli... Read more »
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ChIP-seq
Targeting Macrophage Histone H3 Modification as a Leishmania Strate...
Published: February, 2020
Abstract: Aberrant macrophage activation during intracellular infection generates immunopathologies that can cause severe human morbidity. A better understan... Read more »
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Antibody

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