Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

CPEB1 coordinates alternative 3'-UTR formation with translational r...
Published: March, 2013

Abstract: More than half of mammalian genes generate multiple messenger RNA isoforms that differ in their 3' untranslated regions (3' UTRs) and therefore in ... Read more »

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Bioruptor Cell Lysis Western Blot
Shift from extracellular signal-regulated kinase to AKT/cAMP respon...
Published: March, 2013

Abstract: Spinal muscular atrophy (SMA), a recessive neurodegenerative disease, is characterized by the selective loss of spinal motor neurons. No available ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Adipose subtype-selective recruitment of TLE3 or Prdm16 by PPARγ sp...
Published: March, 2013

Abstract: Transcriptional effectors of white adipocyte-selective gene expression have not been described. Here we show that TLE3 is a white-selective cofacto... Read more »

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Master Mix
Epigenetic hierarchy within the MAGEA1 cancer-germline gene: promot...
Published: March, 2013

Abstract: Gene MAGEA1 belongs to a group of human germline-specific genes that rely on DNA methylation for repression in somatic tissues. Many of these genes... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Antibody
Acetylation limits 53BP1 association with damaged chromatin to prom...
Published: March, 2013

Abstract: The pathogenic sequelae of BRCA1 mutation in human and mouse cells are mitigated by concomitant deletion of 53BP1, which binds histone H4 dimethyla... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
H2A.Z and H2B.Z double-variant nucleosomes define intergenic region...
Published: March, 2013

Abstract: Histone variants are important components of eukaryotic chromatin and can alter chromatin structure to confer specialized functions. H2B variant hi... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Myod and H19-Igf2 locus interactions are required for diaphragm for...
Published: March, 2013

Abstract: The myogenic regulatory factor Myod and insulin-like growth factor 2 (Igf2) have been shown to interact in vitro during myogenic differentiation. I... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR HighCell ChIP kit
Naive pluripotency is associated with global DNA hypomethylation.
Published: March, 2013

Abstract: Naive pluripotent embryonic stem cells (ESCs) and embryonic germ cells (EGCs) are derived from the preimplantation epiblast and primordial germ cel... Read more »

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Antibody 5mC (C15200081)
Chromatin immunoprecipitation of adult murine cardiomyocytes.
Published: March, 2013

Abstract: This unit describes a streamlined two-step protocol for the isolation of adult murine cardiomyocytes with subsequent Chromatin ImmunoPrecipitation ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Genome-wide control of RNA polymerase II activity by cohesin.
Published: March, 2013

Abstract: Cohesin is a well-known mediator of sister chromatid cohesion, but it also influences gene expression and development. These non-canonical roles of... Read more »

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Bioruptor Chromatin Shearing
Activating RNAs associate with Mediator to enhance chromatin archit...
Published: February, 2013

Abstract: Recent advances in genomic research have revealed the existence of a large number of transcripts devoid of protein-coding potential in multiple org... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
H3K4me3 interactions with TAF3 regulate preinitiation complex assem...
Published: February, 2013

Abstract: Histone modifications regulate chromatin-dependent processes, yet the mechanisms by which they contribute to specific outcomes remain unclear. H3K4... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
H2-independent growth of the hydrogenotrophic methanogen Methanococ...
Published: February, 2013

Abstract: UNLABELLED: Hydrogenotrophic methanogenic Archaea require reduced ferredoxin as an anaplerotic source of electrons for methanogenesis. H(2) oxidati... Read more »

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DNA shearing Bioruptor
Endogenous purification reveals GREB1 as a key estrogen receptor re...
Published: February, 2013

Abstract: Estrogen receptor-α (ER) is the driving transcription factor in most breast cancers, and its associated proteins can influence drug response, but d... Read more »

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Bioruptor Cell Lysis
Dynamics of 5-hydroxymethylcytosine and chromatin marks in Mammalia...
Published: February, 2013

Abstract: DNA methylation in mammals is highly dynamic during germ cell and preimplantation development but is relatively static during the development of so... Read more »

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Antibody
SOX2 co-occupies distal enhancer elements with distinct POU factors...
Published: February, 2013

Abstract: SOX2 is a master regulator of both pluripotent embryonic stem cells (ESCs) and multipotent neural progenitor cells (NPCs); however, we currently la... Read more »

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Bioruptor Chromatin Shearing ChIP-seq IP-Star
Histone-methyltransferase MLL2 (KMT2B) is required for memory forma...
Published: February, 2013

Abstract: The consolidation of long-term memories requires differential gene expression. Recent research has suggested that dynamic changes in chromatin stru... Read more »

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LowCell ChIP kit
Mitochondrial phylogenomics of modern and ancient equids.
Published: February, 2013

Abstract: The genus Equus is richly represented in the fossil record, yet our understanding of taxonomic relationships within this genus remains limited. To ... Read more »

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DNA shearing Bioruptor
Polycomb domain formation depends on short and long distance regula...
Published: February, 2013

Abstract: BACKGROUND: Polycomb group (PcG) proteins dynamically define cellular identities through the epigenetic repression of key developmental genes. In D... Read more »

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Bioruptor Chromatin Shearing
Inhibition of neural crest formation by Kctd15 involves regulation ...
Published: February, 2013

Abstract: The neural crest develops in vertebrate embryos within a discrete domain at the neural plate boundary and eventually gives rise to a migrating popu... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
ARCH domain of XPD, an anchoring platform for CAK that conditions T...
Published: February, 2013

Abstract: The xeroderma pigmentosum group D (XPD) helicase is a subunit of transcription/DNA repair factor, transcription factor II H (TFIIH) that catalyzes ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Multiple roles for Piwi in silencing Drosophila transposons.
Published: February, 2013

Abstract: Silencing of transposons in the Drosophila ovary relies on three Piwi family proteins--Piwi, Aubergine (Aub), and Ago3--acting in concert with thei... Read more »

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Bioruptor Chromatin Shearing ChIP-seq
Regulation of transcription through acetylation of H3K122 on the la...
Published: February, 2013

Abstract: Histone modifications are key regulators of chromatin function. However, little is known to what extent histone modifications can directly impact o... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Antibody H3K4me3 (C15410003)
Krüppel-like factor 2 is required for normal mouse cardiac developm...
Published: February, 2013

Abstract: Krüppel-like factor 2 (KLF2) is expressed in endothelial cells in the developing heart, particularly in areas of high shear stress, such as the atr... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Identification of thyroid hormone response elements in vivo using m...
Published: February, 2013

Abstract: Thyroid hormone receptor alpha 1 (TRα1) is well recognized for its importance in brain development. However, due to the difficulties in predicting ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
SUMOylation of the inducible (c-Fos:c-Jun)/AP-1 transcription compl...
Published: February, 2013

Abstract: The inducible proto-oncogenic (c-Fos:c-Jun)/AP-1 transcription complex binds 12-O-tetradecanoylphorbol 13-acetate (TPA)-responsive elements (TRE) i... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
DNA methylation analysis in the intestinal epithelium-effect of cel...
Published: February, 2013

Abstract: BACKGROUND: Epigenetic signatures are highly cell type specific. Separation of distinct cell populations is therefore desirable for all epigenetic ... Read more »

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DNA shearing Bioruptor Antibody 5mC (C15200081)
Consequences of normalizing transcriptomic and genomic libraries of...
Published: February, 2013

Abstract: Several applications of high throughput genome and transcriptome sequencing would benefit from a reduction of the high-copy-number sequences in the... Read more »

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DNA shearing Bioruptor
DNA methylation mediated control of gene expression is critical for...
Published: February, 2013

Abstract: Crown gall tumors develop after integration of the T-DNA of virulent Agrobacterium tumefaciens strains into the plant genome. Expression of the T-D... Read more »

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DNA shearing Bioruptor Antibody
Identification and functional validation of HPV-mediated hypermethy...
Published: February, 2013

Abstract: BACKGROUND: Human papillomavirus-positive (HPV+) head and neck squamous cell carcinoma (HNSCC) represents a distinct clinical and epidemiological c... Read more »

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IP-Star

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