Publications,References

Next-Generation Sequencing Reveals Deep Intronic Cryptic ABCC8 and ...
Published: December, 2012

Abstract: Next-generation sequencing (NGS) enables analysis of the human genome on a scale previously unachievable by Sanger sequencing. Exome sequencing of ... Read more »

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DNA shearing Bioruptor

AMPK Is a Negative Regulator of the Warburg Effect and Suppresses T...
Published: December, 2012

Abstract: AMPK is a metabolic sensor that helps maintain cellular energy homeostasis. Despite evidence linking AMPK with tumor suppressor functions, the role... Read more »

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Bioruptor Cell Lysis

Epigenetic Regulation of Nestin Expression During Neurogenic Differ...
Published: December, 2012

Abstract: Adipose-tissue-derived stem cells (ASCs) have received considerable attention due to their easy access, expansion potential, and differentiation ca... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Antibody H3K27me3 (C15410069)

MeCP2 Binds to 5hmC Enriched within Active Genes and Accessible Chr...
Published: December, 2012

Abstract: The high level of 5-hydroxymethylcytosine (5hmC) present in neuronal genomes suggests that mechanisms interpreting 5hmC in the CNS may differ from ... Read more »

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Antibody

A Molecular Roadmap of Reprogramming Somatic Cells into iPS Cells.
Published: December, 2012

Abstract: Factor-induced reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) is inefficient, complicating mechanistic studies. Here, w... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

The Potential for Isocitrate Dehydrogenase Mutations to Produce 2-H...
Published: December, 2012

Abstract: Monoallelic point mutations in cytosolic isocitrate dehydrogenase 1 (IDH1) and its mitochondrial homolog IDH2 can lead to elevated levels of 2-hydr... Read more »

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Bioruptor Cell Lysis Western Blot Bioruptor Plus

HDAC1-mSin3a-NCOR1, Dnmt3b-HDAC1-Egr1 and Dnmt1-PCNA-UHRF1-G9a regu...
Published: December, 2012

Abstract: The NY-ESO1 gene is a cancer/testis antigen considered to be suitable target for the immunotherapy of human malignancies. Despite the identificatio... Read more »

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Bioruptor Chromatin Shearing MeDIP kit

A polycomb group protein is retained at specific sites on chromatin...
Published: December, 2012

Abstract: Epigenetic regulation of gene expression, including by Polycomb Group (PcG) proteins, may depend on heritable chromatin states, but how these state... Read more »

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DNA shearing Bioruptor Bioruptor Plus

Hypoxia-inducible Factor 1α regulates a Socs3-Stat3-adiponectin sig...
Published: December, 2012

Abstract: Obesity has been identified as a major risk factor for type 2 diabetes, characterized by insulin resistance in insulin target tissues. Hypoxia-indu... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

The EP300, KDM5A, KDM6A and KDM6B Chromatin Regulators Cooperate wi...
Published: December, 2012

Abstract: POU5F1 is essential for maintaining pluripotency in embryonic stem cells (ESCs). It has been reported that the constitutive activation of POU5F1 is... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Nano-MeDIP-seq: Methylome analysis using low DNA concentrations (Pr...
Published: December, 2012

Abstract: To understand the functional consequences of DNA methylation on phenotypic plasticity, a genome - wide analysis should be embraced. This in turn re... Read more »

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DNA shearing Bioruptor IP-Star

A Genome-Wide RNAi Screen Reveals MAP Kinase Phosphatases as Key ER...
Published: December, 2012

Abstract: Embryonic stem cells and induced pluripotent stem cells represent potentially important therapeutic agents in regenerative medicine. Complex interl... Read more »

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Bioruptor Cell Lysis Western Blot

TET2 promotes histone O-GlcNAcylation during gene transcription.
Published: December, 2012

Abstract: Ten eleven translocation (TET) enzymes, including TET1, TET2 and TET3, convert 5-methylcytosine to 5-hydroxymethylcytosine and regulate gene transc... Read more »

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DNA shearing Bioruptor

High-resolution transcriptome and genome-wide dynamics of RNA polym...
Published: December, 2012

Abstract: To construct a regulatory map of the genome of the human pathogen, Mycobacterium tuberculosis, we applied two complementary high-resolution approac... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

STAT3 Protein Up-regulates Gα-interacting Vesicle-associated Protei...
Published: December, 2012

Abstract: Gα-interacting vesicle-associated protein (GIV) is a guanine nucleotide exchange factor that modulates key signaling pathways during a diverse set ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

A Histone Deacetylase Adjusts Transcription Kinetics at Coding Sequ...
Published: December, 2012

Abstract: Despite their classical role as transcriptional repressors, several histone deacetylases, including the baker's yeast Set3/Hos2 complex (Set3C), fa... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Recurrent targeted genes of hepatitis B virus in the liver cancer g...
Published: December, 2012

Abstract: Integration of the viral DNA into host chromosomes was found in most of the hepatitis B virus (HBV)-related hepatocellular carcinomas (HCCs). Here ... Read more »

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DNA shearing Bioruptor

Conserved boundary elements from the Hox complex of mosquito, Anoph...
Published: December, 2012

Abstract: The conservation of hox genes as well as their genomic organization across the phyla suggests that this system of anterior-posterior axis formation... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Scmh1 has E3 ubiquitin ligase activity for Geminin and histone H2A ...
Published: December, 2012

Abstract: Polycomb-group (PcG) complex 1 acts as an E3 ubiquitin ligase both for histone H2A to silence transcription and for Geminin to regulate its stabili... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR LowCell ChIP kit

Population genomics of Pacific lamprey: adaptive variation in a hig...
Published: December, 2012

Abstract: Unlike most anadromous fishes that have evolved strict homing behaviour, Pacific lamprey (Entosphenus tridentatus) seem to lack philopatry as evide... Read more »

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DNA shearing Bioruptor Bioruptor Plus

Control of somatic tissue differentiation by the long non-coding RN...
Published: December, 2012

Abstract: Several of the thousands of human long non-coding RNAs (lncRNAs) have been functionally characterized; however, potential roles for lncRNAs in soma... Read more »

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Bioruptor Cell Lysis

ATF4 orchestrates a program of BH3-only protein expression in sever...
Published: December, 2012

Abstract: Intratumoral hypoxia is associated with poor prognosis, regardless of the mode of therapy. Cancer cells survive this condition through activating s... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Mechanistic and structural insight into the functional dichotomy be...
Published: December, 2012

Abstract: Interleukin 15 (IL-15) and IL-2 have distinct immunological functions even though both signal through the receptor subunit IL-2Rβ and the common γ-... Read more »

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DNA shearing Bioruptor

Comparative genome-wide DNA methylation analysis of colorectal tumo...
Published: December, 2012

Abstract: Aberrant DNA methylation often occurs in colorectal cancer (CRC). In our study we applied a genome-wide DNA methylation analysis approach, MethylCa... Read more »

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IP-Star Antibody

Genome Sequence of OXA-48 Carbapenemase-Producing Klebsiella pneumo...
Published: December, 2012

Abstract: Klebsiella pneumoniae KpO3210 is a OXA-48 carbapenemase-producing isolate obtained from a blood culture in the context of an outbreak in Hospital U... Read more »

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DNA shearing Bioruptor

Bone morphogenetic protein-7 regulates Snail signaling in carbon te...
Published: December, 2012

Abstract: The aim of this study was to explore the molecular mechanism of the bone morphogenetic protein-7 (BMP-7) downregulation of Snail-mediated E-cadheri... Read more »

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Bioruptor Cell Lysis Enzymatic Assay

Ezh2 maintains a key phase of muscle satellite cell expansion but d...
Published: November, 2012

Abstract: Tissue generation and repair requires a stepwise process of cell fate restriction to ensure adult stem cells differentiate in a timely and appropri... Read more »

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Bioruptor Chromatin Shearing ChIP-seq Antibody H3K4me3 (C15410003)

Cdk11-CyclinL Controls the Assembly of the RNA Polymerase II Mediat...
Published: November, 2012

Abstract: The large Mediator (L-Mediator) is a general coactivator of RNA polymerase II transcription and is formed by the reversible association of the smal... Read more »

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Bioruptor Chromatin Shearing

A Comparison of the Whole Genome Approach of MeDIP-Seq to the Targe...
Published: November, 2012

Abstract: DNA methylation is one of the most studied epigenetic marks in the human genome, with the result that the desire to map the human methylome has dri... Read more »

Ubiquitin-dependent regulation of phospho-AKT dynamics by the ubiqu...
Published: November, 2012

Abstract: AKT is a critical effector kinase downstream of the PI3K pathway that regulates a plethora of cellular processes including cell growth, death, diff... Read more »

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Cell Lysis Enzymatic Assay

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