Publications,References

Distinct roles for Sir2 and RNAi in centromeric heterochromatin nuc...
Published: April, 2013

Abstract: Epigenetically regulated heterochromatin domains govern essential cellular activities. A key feature of heterochromatin domains is the presence of ... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

Acyl-CoA synthetase 1 is induced by Gram-negative bacteria and lipo...
Published: April, 2013

Abstract: The enzyme acyl-CoA synthetase 1 (ACSL1) is induced by peroxisome proliferator-activated receptor α (PPARα) and PPARγ in insulin target tissues, su... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

Functional variants at the 11q13 risk locus for breast cancer regul...
Published: April, 2013

Abstract: Analysis of 4,405 variants in 89,050 European subjects from 41 case-control studies identified three independent association signals for estrogen-r... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

Utx is required for proper induction of ectoderm and mesoderm durin...
Published: April, 2013

Abstract: Embryonic development requires chromatin remodeling for dynamic regulation of gene expression patterns to ensure silencing of pluripotent transcrip... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR Antibody

Akt kinase targets the association of CBP with histone H3 to regula...
Published: April, 2013

Abstract: CREB binding protein (CBP) is an acetyltransferase that plays an important role in many biological processes. Here, we show that Akt phosphorylates... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

Genome-wide analysis of LXRα activation reveals new transcriptional...
Published: April, 2013

Abstract: Increased physiological levels of oxysterols are major risk factors for developing atherosclerosis and cardiovascular disease. Lipid-loaded macroph... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR ChIP-seq Antibody H3K4me3 (C15410003)

A systemic transcriptome analysis reveals the regulation of neural ...
Published: April, 2013

Abstract: Stem cell fate decisions are controlled by a molecular network in which transcription factors and miRNAs are of key importance. To systemically inv... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

Control of human adenovirus type 5 gene expression by cellular Daxx...
Published: April, 2013

Abstract: Death domain-associated protein (Daxx) cooperates with X-linked α-thalassaemia retardation syndrome protein (ATRX), a putative member of the sucros... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

Modulation of gene expression via overlapping binding sites exerted...
Published: April, 2013

Abstract: ZNF143 is a zinc-finger protein involved in the transcriptional regulation of both coding and non-coding genes from polymerase II and III promoters... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-seq

Genome-wide comparison of DNA hydroxymethylation in mouse embryonic...
Published: April, 2013

Abstract: The genome-wide distribution patterns of the '6th base' 5-hydroxymethylcytosine (5hmC) in many tissues and cells have recently been revealed by hyd... Read more »

Tags
DNA shearing Bioruptor

Multiple functions of Kip-related protein5 connect endoreduplicatio...
Published: April, 2013

Abstract: Despite considerable progress in our knowledge regarding the cell cycle inhibitor of the Kip-related protein (KRP) family in plants, less is known ... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-seq IPure kit

A pseudogene long-noncoding-RNA network regulates PTEN transcriptio...
Published: April, 2013

Abstract: PTEN is a tumor-suppressor gene that has been shown to be under the regulatory control of a PTEN pseudogene expressed noncoding RNA, PTENpg1. Here,... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

Multiple interferon regulatory factor and NF-κB sites cooperate in ...
Published: April, 2013

Abstract: CD83 is one of the best-known surface markers for fully mature dendritic cells (mature DCs), and its cell-type- and maturation-specific regulation ... Read more »

Duration of fecal shedding of Shiga toxin-producing Escherichia col...
Published: April, 2013

Abstract: BACKGROUND: In May-July 2011, Germany experienced a large food-borne outbreak of Shiga toxin 2-producing Escherichia coli (STEC O104:H4) with 3842 ... Read more »

Tags
DNA shearing Bioruptor

De novo sequencing of hazelnut bacterial artificial chromosomes (BA...
Published: April, 2013

Abstract: Bacterial artificial chromosome (BAC) libraries are widely used in map-based cloning of plant genes. Eastern filbert blight (EFB), caused by the py... Read more »

Tags
DNA shearing Bioruptor

Epigenetic and molecular signature of human umbilical cord blood-de...
Published: April, 2013

Abstract: In the context of cell therapy, the epigenetic status of core stemness transcription factor (STF) genes regulating the cell proliferation/different... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus

Epigenetic upregulation of lncRNAs at 13q14.3 in leukemia is linked...
Published: April, 2013

Abstract: Non-coding RNAs are much more common than previously thought. However, for the vast majority of non-coding RNAs, the cellular function remains enig... Read more »

Tags
DNA shearing Bioruptor Chromatin Shearing ChIP-qPCR

Intrinsic epigenetic regulation of the D4Z4 macrosatellite repeat i...
Published: April, 2013

Abstract: Facioscapulohumeral dystrophy (FSHD) is a progressive muscular dystrophy caused by decreased epigenetic repression of the D4Z4 macrosatellite repea... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

DNA double-strand breaks coupled with PARP1 and HNRNPA2B1 binding s...
Published: April, 2013

Abstract: Genome instability plays a key role in multiple biological processes and diseases, including cancer. Genome-wide mapping of DNA double-strand break... Read more »

Multiple IRF- and NFkB-sites cooperate in mediating cell type- and ...
Published: April, 2013

Abstract: CD83 is one of the best-known surface marker for fully mature dendritic cells (DCs) and its cell type- and maturation-specific regulation makes the... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

Mutations in the nucleolar phosphoprotein, nucleophosmin, promote t...
Published: March, 2013

Abstract: Myeloid ELF1-like factor (MEF/ELF4), a member of the ETS transcription factors, can function as an oncogene in murine cancer models and is overexpr... Read more »

Single-cell dynamics of genome-nuclear lamina interactions.
Published: March, 2013

Abstract: The nuclear lamina (NL) interacts with hundreds of large genomic regions termed lamina associated domains (LADs). The dynamics of these interaction... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

The role of proteasome beta subunits in gastrin-mediated transcript...
Published: March, 2013

Abstract: The hormone gastrin physiologically regulates gastric acid secretion and also contributes to maintaining gastric epithelial architecture by regulat... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus

Topoisomerase IIα promotes activation of RNA polymerase I transcrip...
Published: March, 2013

Abstract: Type II DNA topoisomerases catalyse DNA double-strand cleavage, passage and re-ligation to effect topological changes. There is considerable intere... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR IPure kit

Epigenetic reactivation of Nrf2 in murine prostate cancer TRAMP C1 ...
Published: March, 2013

Abstract: Cancer development has been linked to epigenetic modifications of cancer oncogenes and tumor suppressor genes; in advanced metastatic cancers, seve... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR MagMeDIP kit

The BEN domain is a novel sequence-specific DNA-binding domain cons...
Published: March, 2013

Abstract: We recently reported that Drosophila Insensitive (Insv) promotes sensory organ development and has activity as a nuclear corepressor for the Notch ... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-seq

Quality evaluation of methyl binding domain based kits for enrichme...
Published: March, 2013

Abstract: DNA-methylation is an important epigenetic feature in health and disease. Methylated sequence capturing by Methyl Binding Domain (MBD) based enrich... Read more »

Tags
MethylCap

Fission yeast CSL proteins function as transcription factors.
Published: March, 2013

Abstract: BACKGROUND: Transcription factors of the CSL (CBF1/RBP-Jk/Suppressor of Hairless/LAG-1) family are key regulators of metazoan development and funct... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

PRC1 coordinates timing of sexual differentiation of female primord...
Published: March, 2013

Abstract: In mammals, sex differentiation of primordial germ cells (PGCs) is determined by extrinsic cues from the environment. In mouse female PGCs, express... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

Genomic evidence for island population conversion resolves conflict...
Published: March, 2013

Abstract: Despite extensive genetic analysis, the evolutionary relationship between polar bears (Ursus maritimus) and brown bears (U. arctos) remains unclear... Read more »

Tags
DNA shearing Bioruptor

Publications

活动