Publications,References

Systematic discovery and functional dissection of enhancers needed ...
Published: November, 2022

Abstract: A scarcity of functionally validated enhancers in the human genome presents a significant hurdle to understanding how these cis-regulatory elements... Read more »

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Antibody

Mitochondrial RNA editing in Trypanoplasma borreli: new tools, newr...
Published: November, 2022

Abstract: The kinetoplastids are unicellular flagellates that derive their name from the ‘kinetoplast’, a region within their single mitochondrio... Read more »

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Megaruptor

Identification of an E3 ligase that targets the catalytic subunit o...
Published: November, 2022

Abstract: RNA polymerase I (Pol I) synthesizes ribosomal RNA (rRNA), which is the first and rate-limiting step in ribosome biogenesis. Factors governing the ... Read more »

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iDeal ChIP-seq Kit for Transcription Factors Beads

Histone Deacetylases 1 and 2 target gene regulatory networks of nep...
Published: November, 2022

Abstract: Our studies demonstrated the critical role of Histone deacetylases (HDACs) in the regulation of nephrogenesis. To better understand the key pathway... Read more »

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Antibody iDeal ChIP-seq Kit for Transcription Factors Chromatin Profiling (ChIP-seq) Services

Efficacy of selective histone deacetylase 6 inhibition in mouse mod...
Published: October, 2022

Abstract: The latest studies identified the histone deacetylase (HDAC) class of enzymes as strategic components of the complex molecular machinery underlying... Read more »

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Antibody

The telomeric protein TERF2/TRF2 impairs HMGB1-driven autophagy.
Published: October, 2022

Abstract: TERF2/TRF2 is a pleiotropic telomeric protein that plays a crucial role in tumor formation and progression through several telomere-dependent and -... Read more »

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Antibody

Semi-automated assembly of high-quality diploid human reference gen...
Published: October, 2022

Abstract: The current human reference genome, GRCh38, represents over 20 years of effort to generate a high-quality assembly, which has benefitted society. H... Read more »

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Megaruptor

Rapid and comprehensive diagnostic method for repeat expansion dise...
Published: October, 2022

Abstract: We developed a diagnostic method for repeat expansion diseases using a long-read sequencer to improve currently available, low throughput diagnosti... Read more »

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Megaruptor

Integration of Hi-C with short and long-read genome sequencingrevea...
Published: October, 2022

Abstract: Structural variants are a common cause of disease and contribute to a large extent to inter-individual variability, but their detection and interpr... Read more »

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Megaruptor

Characterization of somatic structural variations in 528 Chineseind...
Published: October, 2022

Abstract: Esophageal squamous cell carcinoma (ESCC) demonstrates high genome instability. Here, we analyze 528 whole genomes to investigate structural variat... Read more »

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Megaruptor

Systems-biology analysis of rheumatoid arthritis fibroblast-likesyn...
Published: October, 2022

Abstract: Rheumatoid arthritis (RA) is an immune-mediated disease affecting diarthrodial joints that remains an unmet medical need despite improved therapy. ... Read more »

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Antibody

Viral transduction of primary human lymphoma B cells reveals mechan...
Published: October, 2022

Abstract: Hotspot mutations in the PEST-domain of NOTCH1 and NOTCH2 are recurrently identified in B cell malignancies. To address how NOTCH-mutations contrib... Read more »

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Antibody

Vitamin C enhances NF-κB-driven epigenomic reprogramming andboosts ...
Published: October, 2022

Abstract: Dendritic cells (DCs), the most potent antigen-presenting cells, are necessary for effective activation of naïve T cells. DCs' immunological p... Read more »

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Antibody IPure kit

The Capparis spinosa var. herbacea genome provides the first genomi...
Published: October, 2022

Abstract: BACKGROUND: The caper bush Capparis spinosa L., one of the most economically important species of Capparaceae, is a xerophytic shrub that is well a... Read more »

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Megaruptor

Genomic Characterization and Antimicrobial Susceptibility ofDromeda...
Published: October, 2022

Abstract: Members of the family, particularly those of the genus Staphylococcus, encompass important human and animal pathogens. We collected and characteriz... Read more »

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Megaruptor

The genome sequence of the orange-tip butterfly, Anthocharis cardam...
Published: October, 2022

Abstract: We present a genome assembly from an individual female Anthocharis cardamines (the orange-tip; Arthropoda; Insecta; Lepidoptera; Pieridae). The gen... Read more »

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Megaruptor

The genome sequence of the satellite, Eupsilia transversa (Hufnagel...
Published: October, 2022

Abstract: We present a genome assembly from an individual female Eupsilia transversa (the satellite; Arthropoda; Insecta; Lepidoptera; Noctuidae). The genome... Read more »

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Antibody

The genome sequence of the common yellow swallowtail, Papilio macha...
Published: October, 2022

Abstract: We present a genome assembly from an individual female Papilio machaon (the common yellow swallowtail; Arthropoda; Insecta; Lepidoptera; Papilionid... Read more »

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Antibody

The genome sequence of the Arran brown, Erebia ligea (Linnaeus,1758)
Published: October, 2022

Abstract: We present a genome assembly from an individual male Erebia ligea (Arran brown; Arthropoda; Insecta; Lepidoptera; Nymphalidae). The genome sequence... Read more »

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Megaruptor

The piRNA-pathway factor FKBP6 is essential for spermatogenesis but...
Published: October, 2022

Abstract: Infertility affects around 7\% of the male population and can be due to severe spermatogenic failure (SPGF), resulting in no or very few sperm in t... Read more »

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D-Plex small RNA-seq

A transition phase in late mouse oogenesis impacts DNA methylation ...
Published: October, 2022

Abstract: A well-orchestrated program of oocyte growth and differentiation results in a developmentally competent oocyte. In late oogenesis, germinal vesicle... Read more »

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Antibody

Monitoring autochthonous lung tumors induced by somatic CRISPR gene...
Published: October, 2022

Abstract: BACKGROUND: In vivo gene editing of somatic cells with CRISPR nucleases has facilitated the generation of autochthonous mouse tumors, which are ini... Read more »

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Antibody CRISPR

Trained Immunity Provides Long-Term Protection againstBacterial Inf...
Published: October, 2022

Abstract: Beta glucan exposure induced trained immunity in channel catfish that conferred long-term protection against and infections one month post exposure... Read more »

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Antibody

Optimized single-nucleus transcriptional profiling by combinatorial...
Published: October, 2022

Abstract: Single-cell combinatorial indexing RNA sequencing (sci-RNA-seq) is a powerful method for recovering gene expression data from an exponentially scal... Read more »

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Tagmentase

The cell-free DNA methylome captures distinctions between localized...
Published: October, 2022

Abstract: Metastatic prostate cancer remains a major clinical challenge and metastatic lesions are highly heterogeneous and difficult to biopsy. Liquid biops... Read more »

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MagMeDIP kit IPure kit

The seminal plasma microbiome of men with testicular germ cell tumo...
Published: September, 2022

Abstract: Background: It has been estimated that microorganisms are involved in the pathogenesis of approximately 20% of all cancers. Testicular germ ce... Read more »

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D-Plex small RNA-seq

Epigenetic Suppression of the IL-7 Pathway in ProgressiveGlioblastoma.
Published: September, 2022

Abstract: BACKGROUND: Immune evasion in glioblastoma (GBM) shields cancer cells from cytotoxic immune response. METHODS: We investigated CpG methylation in p... Read more »

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Premium RRBS Kit

Massively parallel multi-target CRISPR system interrogates Cas9-bas...
Published: September, 2022

Abstract: CRISPR-Cas9 nucleases, and particularly Streptococcus pyogenes Cas9, are widespread tools for genome editing. However, many aspects of intracellula... Read more »

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CRISPR

Manganese-Induced Toxicity in : What Can We Learn from theTranscrip...
Published: September, 2022

Abstract: Manganese (Mn) is an essential ubiquitous transition metal and, when occupationally or environmentally overexposed, a well-known risk factor for se... Read more »

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D-Plex mRNA-seq kit

Linked-read whole-genome sequencing resolves common and privatestru...
Published: September, 2022

Abstract: Multiple myeloma (MM) is an incurable and aggressive plasma cell malignancy characterized by a complex karyotype with multiple structural variants ... Read more »

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Antibody

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