Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Detection of DNA methylation by MeDIP and MBDCap assays: an overvie...

Abstract: DNA methylation has been characterized as the representative example of epigenetic modifications and implicated in numerous biological processes, s... Read more »

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DNA shearing Bioruptor Antibody
Mapping replication origin sequences in eukaryotic chromosomes.

Abstract: Recent advances in genome-sequencing technology have led to the complete mapping of DNA replication initiation sites in the human genome. This thor... Read more »

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DNA shearing Bioruptor
ChIP-seq profiling of the active chromatin marker H3K4me3 and PPARγ...

Abstract: Transcription factors (TFs) represent key factors to establish a cellular phenotype. It is known that several TFs could play a role in disease, yet... Read more »

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Bioruptor Chromatin Shearing ChIP-seq
Integrative analysis of glucometabolic traits, adipose tissue DNA m...

Abstract: Decline in insulin sensitivity due to dysfunction of adipose tissue (AT) is one of the earliest pathogenic events in Type 2 Diabetes. We hypothesiz... Read more »
Integrative analysis of glucometabolic traits, adipose tissue DNA m...

Abstract: Decline in insulin sensitivity due to dysfunction of adipose tissue (AT) is one of the earliest pathogenic events in Type 2 Diabetes. We hypothesiz... Read more »
PRAME induces genomic instability in uveal melanoma

Abstract: PRAME is a CUL2 ubiquitin ligase subunit that is normally expressed in the testis but becomes aberrantly overexpressed in many cancer types in asso... Read more »

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Antibody
Intracellular MMP-2 Activity in Skeletal Muscle Is Associated With ...

Abstract: Matrix metalloproteinase 2 (MMP-2) is a proteolytic enzyme implicated in motility, differentiation, and regeneration of skeletal muscle fibers thro... Read more »

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Bioruptor Cell Lysis Mass Spectrometry
Chromatin Immunoprecipitation in Mouse Hippocampal Cells and Tissues

Abstract: Chromatin immunoprecipitation (ChIP) has been developed for studying protein-DNA interactions and has been extensively used for mapping the localiz... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Epigenome profiling of specific plant cell types using a streamline...

Abstract: Plants consist of many functionally specialized cell types, each with its own unique epigenome, transcriptome, and proteome. Characterization of th... Read more »

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Bioruptor Chromatin Shearing ChIP-seq
Nucleophosmin 1 cooperates with the methyltransferase DOT1L toregul...

Abstract: The histone methyltransferase DOT1L catalyzes methylation of H3K79 and it is highly conserved in mammals. DOT1L plays a functional role in several ... Read more »

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Bioruptor Antibody
A method for measuring fatty acid oxidation in C. elegans

Abstract: The nematode C. elegans has during the past decade proven to be a valuable model organism to identify and examine molecular mechanisms regulating l... Read more »

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Bioruptor Cell Lysis
Consistency of metagenomic assignment programs in simulated and rea...

Abstract: BACKGROUND: Metagenomics is the genomic study of uncultured environmental samples, which has been greatly facilitated by the advent of shotgun-sequ... Read more »

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DNA shearing Bioruptor
TET1 regulates hypoxia-induced epithelial-mesenchymal transition by...

Abstract: BACKGROUND: Hypoxia induces the epithelial-mesenchymal transition, EMT, to promote cancer metastasis. In addition to transcriptional regulation med... Read more »

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DNA shearing Bioruptor
Temperature-induced switch to the pathogenic yeast form of Histopla...

Abstract: Histoplasma capsulatum, a fungal pathogen of humans, switches from a filamentous spore-forming mold in the soil to a pathogenic budding-yeast form ... Read more »
The DM domain protein DMRT1 is a dose-sensitive regulator of fetal ...

Abstract: Dmrt1 (doublesex and mab-3 related transcription factor 1) is a conserved transcriptional regulator of male differentiation required for testicular... Read more »
Quantitative Proteomics Identifies Activation of Hallmark Pathways ...

Abstract: Molecular pathways regulating melanoma initiation and progression are potential targets of therapeutic development for this aggressive cancer. Iden... Read more »

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Bioruptor Tissue Homogenization
Role of transcriptional and post-transcriptional regulation of meth...

Abstract: Downregulation of liver-specific MAT1Agene, encoding S-adenosylmethionine (SAM) synthesizing isozymes MATI/III, and upregulation of widely expresse... Read more »

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Antibody
BET protein inhibition sensitizes glioblastoma cells to temozolomid...

Abstract: Bromodomain and extra-terminal tail (BET) proteins have been identified as potential epigenetic targets in cancer, including glioblastoma. These ep... Read more »

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Bioruptor Antibody iDeal ChIP-seq Kit for Transcription Factors
UTX mediates demethylation of H3K27me3 at muscle-specific genes dur...

Abstract: Polycomb (PcG) and Trithorax (TrxG) group proteins act antagonistically to establish tissue-specific patterns of gene expression. The PcG protein E... Read more »

 


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