Publications,References

Waves of sumoylation support transcription dynamics during adipocyt...
Published: April, 2021

Abstract: Tight control of gene expression networks required for adipose tissue formation and plasticity is essential for adaptation to energy needs and envi... Read more »

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Microplex Library Preparation kit

Sensitive and reproducible cell-free methylome quantification with ...
Published: April, 2021

Abstract: Background. Cell-free methylated DNA immunoprecipitation-sequencing (cfMeDIP-seq) identifies genomic regions with DNA methylation, using a protocol... Read more »

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Antibody

Complex-dependent histone acetyltransferase activity of KAT8 determ...
Published: April, 2021

Abstract: Acetylation of lysine 16 on histone H4 (H4K16ac) is catalyzed by histone acetyltransferase KAT8 and can prevent chromatin compaction in vitro.... Read more »

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Antibody

The anti-inflammatory cytokine interleukin-37 is an inhibitor of tr...
Published: April, 2021

Abstract: Trained immunity (TI) is a de facto innate immune memory program induced in monocytes/macrophages by exposure to pathogens or vaccines, which evolv... Read more »

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Antibody

Androgen receptor positively regulates gonadotropin-releasing hormo...
Published: April, 2021

Abstract: Within pituitary gonadotropes, the gonadotropin-releasing hormone receptor (GnRHR) receives hypothalamic input from GnRH neurons that is critical f... Read more »

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ChIP Cross-link Gold

Dynamic association of the H3K64 trimethylation mark with genes enc...
Published: April, 2021

Abstract: Epigenetic modifications have emerged as critical regulators of virulence genes and stage-specific gene expression in Plasmodium falciparum. Howeve... Read more »

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Antibody

Multi-omics phenotyping of the gut-liver axis reveals metabolicpert...
Published: April, 2021

Abstract: Health effects of pesticides are not always accurately detected using the current battery of regulatory toxicity tests. We compared standard histop... Read more »

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Premium RRBS Kit

Chd8 regulates X chromosome inactivation in mouse through fine-tuni...
Published: April, 2021

Abstract: Female mammals achieve dosage compensation by inactivating one of their two X chromosomes during development, a process entirely dependent on Xist,... Read more »

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Antibody

Comparative analysis of histone H3K4me3 modifications between blast...
Published: April, 2021

Abstract: Epigenetic changes induced in the early developmental stages by the surrounding environment can have not only short-term but also long-term consequ... Read more »

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Antibody

Genetic perturbation of PU.1 binding and chromatin looping at neutr...
Published: April, 2021

Abstract: Neutrophils play fundamental roles in innate immune response, shape adaptive immunity, and are a potentially causal cell type underpinning genetic ... Read more »

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Antibody

Epigenomic landscape of human colorectal cancer unveils an aberrant...
Published: April, 2021

Abstract: Cancer is characterized by pervasive epigenetic alterations with enhancer dysfunction orchestrating the aberrant cancer transcriptional programs an... Read more »

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Antibody

Complete vertebrate mitogenomes reveal widespread repeats and gened...
Published: April, 2021

Abstract: BACKGROUND: Modern sequencing technologies should make the assembly of the relatively small mitochondrial genomes an easy undertaking. However, few... Read more »

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Megaruptor

Polycomb Repressive Complex 2 and KRYPTONITE regulate pathogen-indu...
Published: April, 2021

Abstract: The Polycomb Repressive Complex 2 (PRC2) is well-known for its role in controlling developmental transitions by suppressing the premature expressio... Read more »

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Antibody Microplex Library Preparation kit

An integrated multi-omics analysis identifies prognostic moleculars...
Published: April, 2021

Abstract: The molecular landscape in non-muscle-invasive bladder cancer (NMIBC) is characterized by large biological heterogeneity with variable clinical out... Read more »

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Microplex Library Preparation kit iDeal ChIP-seq Kit for Histones

Polycystic ovary syndrome is transmitted via a transgenerational ep...
Published: March, 2021

Abstract: Polycystic ovary syndrome (PCOS) is the most common reproductive and metabolic disorder affecting women of reproductive age. PCOS ha... Read more »

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DNA Methylation

Genome-wide DNA methylation and transcriptome integration reveal di...
Published: March, 2021

Abstract: Nearly all human complex traits and diseases exhibit some degree of sex differences, and epigenetics contributes to these differences as DNA methyl... Read more »

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DNA methylation microarray Muscle metabolism Epigenetic sex difference

Cell-free DNA methylome profiling by MBD-seq with ultra-low input
Published: March, 2021

Abstract: Methylation signatures in cell-free DNA (cfDNA) have shown great sensitivity and specificity in the characterization of tumour status and classific... Read more »

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DNA Methylation Liquid biopsy cfDNA Next-generation sequencing Methyl binding protein MBD-seq cfMBD-seq MethylCap kit

ZNF718, HOXA4, and ZFP57 are differentially methylated inperiodonti...
Published: March, 2021

Abstract: OBJECTIVE: To investigate the differences in the epigenomic patterns of DNA methylation in peripheral leukocytes between patients with periodontiti... Read more »

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Infinium Human MethylationEPIC Array Service

Comparison of long read sequencing technologies in interrogating ba...
Published: March, 2021

Abstract: The newest generation of DNA sequencing technology is highlighted by the ability to generate sequence reads hundreds of kilobases in length. Pacifi... Read more »

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Megaruptor

Fra-1 regulates its target genes via binding to remote enhancers wi...
Published: March, 2021

Abstract: The ubiquitous family of dimeric transcription factors AP-1 is made up of Fos and Jun family proteins. It has long been thought to operate principa... Read more »

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Antibody

Loss of SETD1B results in the redistribution of genomic H3K4me3 in ...
Published: March, 2021

Abstract: Histone 3 lysine 4 trimethylation (H3K4me3) is an epigenetic mark found at gene promoters and CpG islands. H3K4me3 is essential for mammalian devel... Read more »

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Antibody Microplex Library Preparation kit

Cell-specific alterations inPitx1regulatory landscape activation ca...
Published: March, 2021

Abstract: Most developmental genes rely on multiple transcriptional enhancers for their accurate expression during embryogenesis. Because enhancers may have ... Read more »

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Antibody

Chromosomal rearrangements but no change of genes and transposable ...
Published: March, 2021

Abstract: Chromosomal rearrangements have been largely described among eukaryotes, and may have important consequences on evolution of species. High genome p... Read more »

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Megaruptor

Transgenic mice for in vivo epigenome editing with CRISPR-based sys...
Published: March, 2021

Abstract: The discovery, characterization, and adaptation of the RNA-guided clustered regularly interspersed short palindromic repeat (CRISPR)-Cas9 system ha... Read more »

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Antibody CRISPR

The aging DNA methylome reveals environment-by-aging interactions i...
Published: March, 2021

Abstract: The rate at which individuals age underlies variation in life history and attendant health and disease trajectories. Age specific patterning of the... Read more »

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Premium RRBS Kit

Unique Patterns of H3K4me3 and H3K27me3 in 2-Cell-like Embryonic St...
Published: March, 2021

Abstract: A small subgroup of embryonic stem cells (ESCs) exhibit molecular features similar to those of two-cell embryos (2C). However, it remains elusive w... Read more »

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Antibody

Epigenomic tensor predicts disease subtypes and reveals constrained...
Published: March, 2021

Abstract: Understanding the epigenomic evolution and specificity of disease subtypes from complex patient data remains a major biomedical problem. We here pr... Read more »

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Antibody

Transcriptional programming drives Ibrutinib-resistance evolution i...
Published: March, 2021

Abstract: Ibrutinib, a bruton's tyrosine kinase (BTK) inhibitor, provokes robust clinical responses in aggressive mantle cell lymphoma (MCL), yet many patien... Read more »

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Antibody

Polycystic ovary syndrome is transmitted via a transgenerational ep...
Published: March, 2021

Abstract: Polycystic ovary syndrome (PCOS) is the most common reproductive and metabolic disorder affecting women of reproductive age. PCOS has a strong heri... Read more »

A regulatory variant at 3q21.1 confers an increased pleiotropic ris...
Published: March, 2021

Abstract: Skeletal and glycemic traits have shared etiology, but the underlying genetic factors remain largely unknown. To identify genetic loci that may hav... Read more »

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Antibody

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