Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Establishment of two homozygous CRISPR interference (CRISPRi)knock-...
Published: August, 2021

Abstract: Using nuclease-deficient dead (d)Cas9 without enzymatic activity fused to transcriptional inhibitors (CRISPRi) allows for transcriptional interfere... Read more »

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Antibody CRISPR
Bisection of the X chromosome disrupts the initiation of chromosome...
Published: August, 2021

Abstract: During meiosis, gene expression is silenced in aberrantly unsynapsed chromatin and in heterogametic sex chromosomes. Initiation of sex chromosome s... Read more »

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Antibody
Evidence of an epidemic spread of KPC-producing in Czech hospitals
Published: August, 2021

Abstract: The aim of the present study is to describe the ongoing spread of the KPC-producing strains, which is evolving to an epidemic in Czech hospitals. D... Read more »

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Megaruptor
Altered Chromatin States Drive Cryptic Transcription in AgingMammal...
Published: August, 2021

Abstract: A repressive chromatin state featuring trimethylated lysine 36 on histone H3 (H3K36me3) and DNA methylation suppresses cryptic transcription in emb... Read more »

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Antibody Microplex Library Preparation kit True MicroChIP kit
Essential role of a ThPOK autoregulatory loop in the maintenance of...
Published: August, 2021

Abstract: The transcription factor ThPOK (encoded by the Zbtb7b gene) controls homeostasis and differentiation of mature helper T cells, while opposing their... Read more »

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iDeal ChIP-seq Kit for Transcription Factors
Niche stiffening compromises hair follicle stem cell potential duri...
Published: July, 2021

Abstract: Tissue turnover requires activation and lineage commitment of tissue-resident stem cells (SCs). These processes are impacted by ageing, but the mec... Read more »

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ChIPmentation
Phase separation drives aberrant chromatin looping and cancerdevelo...
Published: July, 2021

Abstract: The development of cancer is intimately associated with genetic abnormalities that target proteins with intrinsically disordered regions (IDRs). In... Read more »

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Antibody
Light affects behavioral despair involving the clock gene Period 1.
Published: July, 2021

Abstract: Light at night has strong effects on physiology and behavior of mammals. It affects mood in humans, which is exploited as light therapy, and has be... Read more »

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D-Plex RNA-seq kit
Enhanced targeted DNA methylation of the CMV and endogenous promote...
Published: July, 2021

Abstract: With the emergence of new CRISPR/dCas9 tools that enable site specific modulation of DNA methylation and histone modifications, more detailed inves... Read more »

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Antibody iDeal ChIP-qPCR
Complete Genome Sequence of pv. tabaci Strain 6605, a Causal Agent...
Published: July, 2021

Abstract: ABSTRACT Pseudomonas amygdali pv. tabaci strain 6605 is the bacterial pathogen causing tobacco wildfire disease that has been used as a mod... Read more »
Evidence for long-term association of virion-delivered HBV core pro...
Published: July, 2021

Abstract: Background \& Aims HBV persists in the nucleus of infected hepatocytes as a covalently closed circular DNA (cccDNA) episome that constitutes th... Read more »

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Antibody
The USDA-ARS Ag100Pest Initiative: High-Quality GenomeAssemblies fo...
Published: July, 2021

Abstract: Simple Summary High-quality genome assemblies are essential tools for modern biological research. In the past, creating genome assemblies was prohi... Read more »

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Megaruptor
Epigenetic Drifts during Long-Term Intestinal OrganoidCulture
Published: July, 2021

Abstract: Organoids retain the morphological and molecular patterns of their tissue of origin, are self-organizing, relatively simple to handle and accessibl... Read more »

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IP-Star iDeal ChIP-seq Kit for Histones
Metabolically controlled histone H4K5 acylation/acetylation ratiodr...
Published: July, 2021

Abstract: In addition to acetylation, histones are modified by a series of competing longer-chain acylations. Most of these acylation marks are enriched and ... Read more »

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Microplex Library Preparation kit
Single-cell microRNA sequencing method comparison and application t...
Published: July, 2021

Abstract: Molecular single cell analyses provide insights into physiological and pathological processes. Here, in a stepwise approach, we first evaluate 19 p... Read more »

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D-Plex small RNA-seq
Heterogeneity of neurons reprogrammed from spinal cord astrocytes b...
Published: July, 2021

Abstract: Summary Astrocytes are a viable source for generating new neurons via direct conversion. However, little is known about the neurogenic cascades tri... Read more »

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Microplex Library Preparation kit
Expression of in the Stem Cell Domain Is Required for ItsFunction ...
Published: July, 2021

Abstract: In the model plant Arabidopsis thaliana, the zinc-finger transcription factor KNUCKLES (KNU) plays an important role in the termination of floral m... Read more »

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IPure kit Universal Plant ChIP-seq Kit
Environmental enrichment preserves a young DNA methylation landscap...
Published: June, 2021

Abstract: The decline of brain function during aging is associated with epigenetic changes, including DNA methylation. Lifestyle interventions can improve br... Read more »

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Premium RRBS Kit
Riluzole Administration to Rats with Levodopa-Induced Dyskinesia Le...
Published: June, 2021

Abstract: Dyskinesias are characterized by abnormal repetitive involuntary movements due to dysfunctional neuronal activity. Although levodopa-induced dyskin... Read more »

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Premium RRBS Kit
Dnmt1 has de novo activity targeted to transposable elements
Published: June, 2021

Abstract: DNA methylation plays a critical role during development, particularly in repressing retrotransposons. The mammalian methylation landscape is depen... Read more »

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MagMeDIP kit
Therapy-induced DNA methylation inactivates MCT1 and renders tumor ...
Published: June, 2021

Abstract: Metabolic plasticity in cancer cells makes use of metabolism-targeting agents very challenging. Drug-induced metabolic rewiring may, however, uncov... Read more »

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DNA Methylation Methylated DNA immunoprecipitation MagMeDIP qPCR Kit
ChIP-seq protocol for sperm cells and embryos to assess environment...
Published: June, 2021

Abstract: In the field of epigenetic inheritance, delineating molecular mechanisms implicated in the transfer of paternal environmental conditions to descend... Read more »

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Antibody
Familial thrombocytopenia due to a complex structural variant resul...
Published: June, 2021

Abstract: Advances in genome sequencing have resulted in the identification of the causes for numerous rare diseases. However, many cases remain unsolved wit... Read more »

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Megaruptor
The American lobster genome reveals insights on longevity, neural, ...
Published: June, 2021

Abstract: The American lobster, , is integral to marine ecosystems and supports an important commercial fishery. This iconic species also serves as a valuabl... Read more »

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Megaruptor
Epigenetic inheritance of DNA methylation changes in fish living in...
Published: June, 2021

Abstract: Environmental factors can promote phenotypic variation through alterations in the epigenome and facilitate adaptation of an organism to the environ... Read more »

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Antibody
Atg7 deficiency in microglia drives an altered transcriptomic profi...
Published: June, 2021

Abstract: Microglia, resident immunocompetent cells of the central nervous system, can display a range of reaction states and thereby exhibit distinct biolog... Read more »

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iDeal ChIP-qPCR
Analysis of the Coptis chinensis genome reveals the diversification...
Published: June, 2021

Abstract: Chinese goldthread (Coptis chinensis Franch.), a member of the Ranunculales, represents an important early-diverging eudicot lineage with diverse m... Read more »

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Megaruptor
E2F6 initiates stable epigenetic silencing of germline genes during...
Published: June, 2021

Abstract: In mouse development, long-term silencing by CpG island DNA methylation is specifically targeted to germline genes; however, the molecular mechanis... Read more »

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Antibody
Genome-wide CRISPR screen identifies protein pathways modulating ta...
Published: June, 2021

Abstract: Aggregates of hyperphosphorylated tau protein are a pathological hallmark of more than 20 distinct neurodegenerative diseases, including Alzheimer&... Read more »

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Antibody
Environmental enrichment preserves a young DNA methylation landscap...
Published: June, 2021

Abstract: The decline of brain function during aging is associated with epigenetic changes, including DNA methylation. Lifestyle interventions can improve br... Read more »

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Antibody Premium RRBS Kit iDeal ChIP-seq Kit for Transcription Factors

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