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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

NGS analysis of total small non coding RNAs from low input RNA from...
Published: September, 2018
Abstract: Circulating miRNAs are favored for biomarker candidates as they can reflect tissue specific miRNA dysregulation in disease contexts. Moreover, they... Read more »
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CATS
FACT Sets a Barrier for Cell Fate Reprogramming in Caenorhabditis e...
Published: September, 2018
Abstract: The chromatin regulator FACT (facilitates chromatin transcription) is essential for ensuring stable gene expression by promoting transcription. In ... Read more »
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ChIP-seq
Dot1 promotes H2B ubiquitination by a methyltransferase-independent...
Published: September, 2018
Abstract: The histone methyltransferase Dot1 is conserved from yeast to human and methylates lysine 79 of histone H3 (H3K79) on the core of the nucleosome. H... Read more »
Mapping molecular landmarks of human skeletal ontogeny and pluripot...
Published: September, 2018
Abstract: Tissue-specific gene expression defines cellular identity and function, but knowledge of early human development is limited, hampering application ... Read more »
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Antibody LowCell ChIP kit
Loss of H3K27me3 Imprinting in Somatic Cell Nuclear Transfer Embryo...
Published: September, 2018
Abstract: Animal cloning can be achieved through somatic cell nuclear transfer (SCNT), although the live birth rate is relatively low. Recent studies have id... Read more »
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Antibody
mGlu1 Receptors Monopolize the Synaptic Control of Cerebellar Purki...
Published: September, 2018
Abstract: In cerebellar Purkinje cells (PCs) type-1 metabotropic glutamate (mGlu1) receptors play a key role in motor learning and drive the refinement of sy... Read more »
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Antibody
Transcription Elongation Can Affect Genome 3D Structure.
Published: September, 2018
Abstract: How transcription affects genome 3D organization is not well understood. We found that during influenza A (IAV) infection, rampant transcription ra... Read more »
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Antibody
Folic acid supplementation alters the DNA methylation profile and i...
Published: September, 2018
Abstract: Folic acid (FA) supplementation may protect from obesity and insulin resistance, the effects and mechanism of FA on chronic high-fat-diet-induced o... Read more »
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MagMeDIP kit
RNA Sequencing and Pathway Analysis Identify Important Pathways Inv...
Published: September, 2018
Abstract: A growing number of histone modifiers are involved in human neurodevelopmental disorders, suggesting that proper regulation of chromatin state is e... Read more »
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Antibody
Genome-wide measurement of local nucleosome array regularity and sp...
Published: September, 2018
Abstract: The nature of chromatin as regular succession of nucleosomes has gained iconic status. However, since most nucleosomes in metazoans are poorly posi... Read more »
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iDeal Library Preparation Kit
Differential DNA methylation of potassium channel KCa3.1 and immune...
Published: August, 2018
Abstract: Bacillus Calmette-Guérin (BCG) is the only licensed vaccine for tuberculosis (TB) and induces highly variable protection against pulmonary d... Read more »
High-fidelity CRISPR/Cas9- based gene-specific hydroxymethylation r...
Published: August, 2018
Abstract: While suppression of specific genes through aberrant promoter methylation contributes to different diseases including organ fibrosis, gene-specific... Read more »
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OneDay ChIP Kit
Polycomb repressive complex 1 shapes the nucleosome landscape but n...
Published: August, 2018
Abstract: Polycomb group (PcG) proteins are transcriptional repressors that play important roles in regulating gene expression during animal development. In ... Read more »
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Antibody
Lamin B1 mapping reveals the existence of dynamic and functional eu...
Published: August, 2018
Abstract: Lamins (A/C and B) are major constituents of the nuclear lamina (NL). Structurally conserved lamina-associated domains (LADs) are formed by genomic... Read more »
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Beads
Progenitor Hyperpolarization Regulates the Sequential Generation of...
Published: August, 2018
Abstract: During corticogenesis, ventricular zone progenitors sequentially generate distinct subtypes of neurons, accounting for the diversity of neocortical... Read more »
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Antibody
Long-read sequencing across the C9orf72 'GGGGCC' repeat expansion: ...
Published: August, 2018
Abstract: BACKGROUND: Many neurodegenerative diseases are caused by nucleotide repeat expansions, but most expansions, like the C9orf72 'GGGGCC' (GC) repeat ... Read more »
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Megaruptor
Nuclear Receptor Nur77 Limits the Macrophage Inflammatory Response ...
Published: August, 2018
Abstract: Activation of macrophages by inflammatory stimuli induces reprogramming of mitochondrial metabolism to support the production of pro-inflammatory c... Read more »
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Antibody
The complete methylome of an entomopathogenic bacterium reveals the...
Published: August, 2018
Abstract: DNA methylation can serve to control diverse phenomena in eukaryotes and prokaryotes, including gene regulation leading to cell differentiation. In... Read more »
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Megaruptor
Loss of SETDB1 decompacts the inactive X chromosome in part through...
Published: August, 2018
Abstract: BACKGROUND: The product of dosage compensation in female mammals is the inactive X chromosome (Xi). Xi facultative heterochromatin is organized int... Read more »
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Antibody
The Alzheimer's disease-associated TREM2 gene is regulated by p53 t...
Published: August, 2018
Abstract: TREM2 mutations evoke neurodegenerative disorders, and recently genetic variants of this gene were correlated to increased risk of Alzheimer's dise... Read more »
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Antibody iDeal ChIP-seq Kit for Transcription Factors
Genome-wide association study identifies multiple new loci associat...
Published: August, 2018
Abstract: Ewing sarcoma (EWS) is a pediatric cancer characterized by the EWSR1-FLI1 fusion. We performed a genome-wide association study of 733 EWS cases and... Read more »
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iDeal ChIP-seq Kit for Transcription Factors iDeal ChIP-seq Kit for Histones
Human papillomavirus type 16 antagonizes IRF6 regulation of IL-1β.
Published: August, 2018
Abstract: Human papillomavirus type 16 (HPV16) and other oncoviruses have been shown to block innate immune responses and to persist in the host. However, to... Read more »
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OneDay ChIP Kit
Human papillomavirus type 16 antagonizes IRF6 regulation of IL-1β.
Published: August, 2018
Abstract: Human papillomavirus type 16 (HPV16) and other oncoviruses have been shown to block innate immune responses and to persist in the host. However, to... Read more »
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OneDay ChIP Kit
The Arabidopsis LDL1/2-HDA6 histone modification complex is functio...
Published: August, 2018
Abstract: In Arabidopsis, the circadian clock central oscillator genes are important cellular components to generate and maintain circadian rhythms. There is... Read more »
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Antibody
Canonical PRC2 function is essential for mammary gland development ...
Published: August, 2018
Abstract: Distinct transcriptional states are maintained through organization of chromatin, resulting from the sum of numerous repressive and active histone ... Read more »
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Antibody
The histone demethylase Jarid1b mediates angiotensin II-induced end...
Published: August, 2018
Abstract: AIM: The histone demethylase Jarid1b limits gene expression by removing the active methyl mark from histone3 lysine4 at gene promoter regions. A va... Read more »
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ChIP-qPCR
Long-read sequence capture of the haemoglobin gene clusters across ...
Published: August, 2018
Abstract: Combining high-throughput sequencing with targeted sequence capture has become an attractive tool to study specific genomic regions of interest. Mo... Read more »
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Megaruptor
The effect of Jun dimerization on neurite outgrowth and motif binding.
Published: August, 2018
Abstract: Axon regeneration is a necessary step toward functional recovery after spinal cord injury. The AP-1 transcription factor c-Jun has long been known ... Read more »
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ChIP-qPCR
The BRG1/SOX9 axis is critical for acinar cell-derived pancreatic t...
Published: August, 2018
Abstract: Chromatin remodeler Brahma related gene 1 (BRG1) is silenced in approximately 10% of human pancreatic ductal adenocarcinomas (PDAs). We previously ... Read more »
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iDeal ChIP-seq Kit for Transcription Factors
Novel dual regulators of Pseudomonas aeruginosa essential for produ...
Published: August, 2018
Abstract: Gene regulation network in Pseudomonas aeruginosa is complex. With a relatively large genome (6.2 Mb), there is a significant portion of genes that... Read more »
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Antibody

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