Publications,References

Genome methylation and regulatory functions for hypoxic adaptation...
Published: October, 2017

Abstract: Tibetan chickens have unique adaptations to the extreme high-altitude environment that they inhabit. Epigenetic DNA methylation affects many biolog... Read more »

Tags
MagMeDIP kit

Discovery of a selective catalytic p300/CBP inhibitor that targets ...
Published: October, 2017

Abstract: The dynamic and reversible acetylation of proteins, catalysed by histone acetyltransferases (HATs) and histone deacetylases (HDACs), is a major epi... Read more »

Tags
Bioruptor IP-Star Compact

The Role of N-α-acetyltransferase 10 Protein in DNA Methylation and...
Published: October, 2017

Abstract: Genomic imprinting is an allelic gene expression phenomenon primarily controlled by allele-specific DNA methylation at the imprinting control regio... Read more »

Tags
Antibody

The mixed lineage leukemia 4 (MLL4) methyltransferase complex is in...
Published: October, 2017

Abstract: Sma and Mad related (SMAD)-mediated Transforming Growth Factor β (TGF-β) and Bone Morphogenetic Protein (BMP) signaling is required for v... Read more »

Tags
Antibody

De novo PacBio long-read and phased avian genome assemblies correct...
Published: October, 2017

Abstract: Reference-quality genomes are expected to provide a resource for studying gene structure, function, and evolution. However, often genes of interest... Read more »

Tags
Megaruptor

BET-bromodomain inhibitors modulate epigenetic patterns at the diac...
Published: October, 2017

Abstract: BACKGROUND AND PURPOSE: Fibrosis is a frequent adverse effect of radiotherapy and no effective treatments are currently available to prevent or re... Read more »

Tags
IP-Star Compact

Rapid Communication: The correlation between histone modifications ...
Published: October, 2017

Abstract: Histone modification is a well-known epigenetic mechanism involved in regulation of gene expression; however, it has been poorly studied in adipose... Read more »

Tags
Antibody LowCell ChIP kit

TET2- and TDG-mediated changes are required for the acquisition of ...
Published: September, 2017

Abstract: The plasticity of myeloid cells is illustrated by a diversity of functions including their role as effectors of innate immunity as macrophages (MAC... Read more »

Tags
Antibody LowCell ChIP kit

Genomic imprinting of Xist by maternal H3K27me3
Published: September, 2017

Abstract: Maternal imprinting at the Xist gene is essential to achieve paternal allele-specific imprinted X-chromosome inactivation (XCI) in female mammals. ... Read more »

Tags
H3K27me3 (C15410069)

Predicting stimulation-dependent enhancer-promoter interactions fro...
Published: September, 2017

Abstract: We have developed a machine learning approach to predict stimulation-dependent enhancer-promoter interactions using evidence from changes in genomi... Read more »

Tags
Antibody

In trans paired nicking triggers seamless genome editing without do...
Published: September, 2017

Abstract: Precise genome editing involves homologous recombination between donor DNA and chromosomal sequences subjected to double-stranded DNA breaks made b... Read more »

Tags
Antibody

Reproducibility of methylated CpG typing with the Illumina MiSeq
Published: September, 2017

Abstract: DNA methylation patterns may be used for identification of body fluids and for age estimation of human individuals. We evaluated some of the chal... Read more »

Tags
Premium Bisulfite Kit

CDK8/19 Mediator kinases potentiate induction of transcription by NFκB
Published: September, 2017

Abstract: The nuclear factor-κB (NFκB) family of transcription factors has been implicated in inflammatory disorders, viral infections, and cance... Read more »

Tags
Antibody

Histone H4K20 tri-methylation at late-firing origins ensures timely...
Published: September, 2017

Abstract: Among other targets, the protein lysine methyltransferase PR-Set7 induces histone H4 lysine 20 monomethylation (H4K20me1), which is the substrate f... Read more »

Tags
Antibody

UV Radiation Activates Toll-Like Receptor 9 Expression in Primary H...
Published: September, 2017

Abstract: Several lines of evidence indicate that cutaneous human papillomavirus (HPV) types belonging to the beta genus of the HPV phylogenetic tree synergi... Read more »

5-hydroxymethylcytosine accumulation in postmitotic neurons results...
Published: September, 2017

Abstract: 5-hydroxymethylcytosine (5hmC) occurs at maximal levels in postmitotic neurons, where its accumulation is cell-specific and correlated with gene ex... Read more »

Tags
LowCell ChIP kit

Genetic Predisposition to Multiple Myeloma at 5q15 Is Mediated by a...
Published: September, 2017

Abstract: Multiple myeloma (MM) is a malignancy of plasma cells. Genome-wide association studies have shown that variation at 5q15 influences MM risk. Here, ... Read more »

Tags
IP-Star Antibody

MYC drives overexpression of telomerase RNA (hTR/TERC) in prostate ...
Published: September, 2017

Abstract: Telomerase consists of at least two essential elements, an RNA component hTR or TERC that contains the template for telomere DNA addition and a cat... Read more »

Tags
ChIP-qPCR

The cardiac calsequestrin gene transcription is modulated at the pr...
Published: September, 2017

Abstract: Calsequestrin-2 (CASQ2) is the main Ca2+-binding protein inside the sarcoplasmic reticulum of cardiomyocytes. Previously, we demonstrated that MEF-... Read more »

Tags
ChIP-seq

The cardiac calsequestrin gene transcription is modulated at the pr...
Published: September, 2017

Abstract: Calsequestrin-2 (CASQ2) is the main Ca2+-binding protein inside the sarcoplasmic reticulum of cardiomyocytes. Previously, we demonstrated that MEF-... Read more »

The CCAAT box in the proximal SERCA2 gene promoter regulates basal ...
Published: September, 2017

Abstract: The cardiac sarco/endoplasmic reticulum Ca2+-ATPase-2a (SERCA2a) is vital for the correct handling of calcium concentration in cardiomyocytes. Rece... Read more »

MYC drives overexpression of telomerase RNA (hTR/TERC) in prostate ...
Published: September, 2017

Abstract: Telomerase consists of at least two essential elements, an RNA component hTR or TERC that contains the template for telomere DNA addition, and a ca... Read more »

Tags
ChIP-seq

FOXF1 transcription factor promotes lung regeneration after partial...
Published: September, 2017

Abstract: FOXF1, a member of the forkhead box family of transcription factors, has been previously shown to be critical for lung development, homeostasis, an... Read more »

Tags
IP-Star Compact

DNA methylation of intragenic CpG islands depends on their transcri...
Published: September, 2017

Abstract: The human genome contains ∼30,000 CpG islands (CGIs). While CGIs associated with promoters nearly always remain unmethylated, many of the ∼... Read more »

Tags
Antibody

Distinct Circadian Signatures in Liver and Gut Clocks Revealed by K...
Published: September, 2017

Abstract: The circadian clock orchestrates rhythms in physiology and behavior, allowing organismal adaptation to daily environmental changes. While food inta... Read more »

Tags
Antibody

Gene body methylation is involved in coarse genome-wide adjustment ...
Published: September, 2017

Abstract: Gene body methylation (GBM) is a taxonomically widespread epigenetic modification of the DNA the function of which remains unclear 1,2. GBM is bimo... Read more »

Tags
MethylCap

The Hox proteins Ubx and AbdA collaborate with the transcription pa...
Published: September, 2017

Abstract: In metazoans, the pausing of RNA polymerase II at the promoter (paused Pol II) has emerged as a widespread and conserved mechanism in the regulatio... Read more »

A lipodystrophy-causing lamin A mutant alters conformation and epig...
Published: September, 2017

Abstract: Mutations in the Lamin A/C (LMNA) gene-encoding nuclear LMNA cause laminopathies, which include partial lipodystrophies associated with metabolic s... Read more »

Tags
Antibody

Chromosome contacts in activated T cells identify autoimmune diseas...
Published: September, 2017

Abstract: BACKGROUND: Autoimmune disease-associated variants are preferentially found in regulatory regions in immune cells, particularly CD4+ T cells. ... Read more »

Tags
IP-Star Antibody

Transcription of synaptic plasticity-related genes in patients with...
Published: September, 2017

Abstract: Objective: To investigate DNA methylation and hydroxymethylation in patients with somnipathy combined with type 2 diabetes, and to explore the effe... Read more »

Tags
MeDIP kit

Publications

活动