Publications,References

Viral targeting of TFIIB impairs de novo polymerase II recruitment ...
Published: April, 2018

Abstract: Viruses have evolved a plethora of mechanisms to target host antiviral responses. Here, we propose a yet uncharacterized mechanism of immune regula... Read more »

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Bioruptor Bioruptor Plus

HMGB2 Loss upon Senescence Entry Disrupts Genomic Organization and ...
Published: April, 2018

Abstract: Processes like cellular senescence are characterized by complex events giving rise to heterogeneous cell populations. However, the early molecular ... Read more »

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Bioruptor Bioruptor Plus

Combined cistrome and transcriptome analysis of SKI in AML cells id...
Published: April, 2018

Abstract: SKI is a transcriptional co-regulator and overexpressed in various human tumors, for example in acute myeloid leukemia (AML). SKI contributes to th... Read more »

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Microplex Library Preparation kit

Generation of a PAX6 knockout glioblastoma cell line with changes i...
Published: April, 2018

Abstract: The transcription factor PAX6 is expressed in various cancers. In anaplastic astrocytic glioma, PAX6 expression is inversely related to tumor gra... Read more »

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Bioruptor Bioruptor Plus

MYCN acts as a direct co-regulator of p53 in MYCN amplified neurobl...
Published: April, 2018

Abstract: The MYC oncogenes and p53 have opposing yet interrelated roles in normal development and tumorigenesis. How MYCN expression alters the biology and ... Read more »

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Bioruptor

T Cell Receptor-Regulated TGF-β Type I Receptor Expression Determin...
Published: April, 2018

Abstract: It is unclear how quiescence is enforced in naive T cells, but activation by foreign antigens and self-antigens is allowed, despite the presen... Read more »

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HighCell ChIP kit

spe-43 is required for sperm activation in C. elegans.
Published: April, 2018

Abstract: Successful fertilization requires that sperm are activated prior to contacting an oocyte. In C. elegans, this activation process, called spermiogen... Read more »

A long range distal enhancer controls temporal fine-tuning of PAX6 ...
Published: April, 2018

Abstract: Proper embryonic development relies on a tight control of spatial and temporal gene expression profiles in a highly regulated manner. One good exam... Read more »

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Antibody Microplex Library Preparation kit

Pro-inflammatory cytokines activate hypoxia-inducible factor 3α via...
Published: April, 2018

Abstract: Human mesenchymal stromal/stem cells (hMSCs) emerged as a promising therapeutic tool for ischemic disorders, due to their ability to regenerate dam... Read more »

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Antibody

HDAC1 and HDAC2 Modulate TGF-β Signaling during Endothelial-to-Hema...
Published: April, 2018

Abstract: The first hematopoietic stem and progenitor cells are generated during development from hemogenic endothelium (HE) through trans-differentiation. T... Read more »

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HighCell ChIP kit Microplex Library Preparation kit

Contrasting epigenetic states of heterochromatin in the different t...
Published: April, 2018

Abstract: Mouse embryonic stem cells (ESCs) and epiblast stem cells (EpiSCs) represent naive and primed pluripotency states, respectively, and are maintained... Read more »

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True MicroChIP kit

Meg3 Non-coding RNA Expression Controls Imprinting by Preventing Tr...
Published: April, 2018

Abstract: Although many long non-coding RNAs (lncRNAs) are imprinted, their roles often remain unknown. The Dlk1-Dio3 domain expresses the lncRNA Meg3 and mu... Read more »

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Antibody

Molecular Signatures of Regression of the Canine Transmissible Vene...
Published: April, 2018

Abstract: The canine transmissible venereal tumor (CTVT) is a clonally transmissible cancer that regresses spontaneously or after treatment with vincristine,... Read more »

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MagMeDIP kit Antibody IP-Star Compact

Structural and mechanistic insights into UHRF1-mediated DNMT1 activ...
Published: April, 2018

Abstract: UHRF1 plays multiple roles in regulating DNMT1-mediated DNA methylation maintenance during DNA replication. The UHRF1 C-terminal RING finger functi... Read more »

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Antibody

A CLK3-HMGA2 Alternative Splicing Axis Impacts Human Hematopoietic ...
Published: April, 2018

Abstract: While gene expression dynamics have been extensively cataloged during hematopoietic differentiation in the adult, less is known about transcriptome... Read more »

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Antibody

Epigenetics and early domestication: differences in hypothalamic DN...
Published: April, 2018

Abstract: BACKGROUND: Domestication of animals leads to large phenotypic alterations within a short evolutionary time-period. Such alterations are caused by ... Read more »

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Antibody

Draft genome of the Peruvian scallop Argopecten purpuratus.
Published: April, 2018

Abstract: Background: The Peruvian scallop, Argopecten purpuratus, is mainly cultured in southern Chile and Peru was introduced into China in the last centur... Read more »

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Megaruptor

Overview of Next-Generation Sequencing Technologies.
Published: April, 2018

Abstract: High throughput DNA sequencing methodology (next generation sequencing; NGS) has rapidly evolved over the past 15 years and new methods are continu... Read more »

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Megaruptor

CTCF-KDM4A complex correlates with histone modifications that negat...
Published: March, 2018

Abstract: Histone demethylase KDM4A is involved in H3K9me3 and H3K36me3 demethylation, which are epigenetic modifications associated with gene silencing and ... Read more »

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ChIP-qPCR

Comparative Analysis of Immune Cells Reveals a Conserved Regulatory...
Published: March, 2018

Abstract: Most well-characterized enhancers are deeply conserved. In contrast, genome-wide comparative studies of steady-state systems showed that only a sma... Read more »

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Antibody

p27 regulates alpha-synuclein expression.
Published: March, 2018

Abstract: Alpha-synuclein (α-SYN) is the main component of anomalous protein aggregates (Lewy bodies) that play a crucial role in several neurodegenera... Read more »

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IPure kit

Phylogenomic evidence for a recent and rapid radiation of lizards i...
Published: March, 2018

Abstract: Rapid evolutionary radiations are difficult to resolve because divergence events are nearly synchronous and gene flow among nascent species can be ... Read more »

Application of next-generation sequencing to characterize novel mut...
Published: March, 2018

Abstract: Clarithromycin (CLR) resistance has become a predominant factor for treatment failure of H. pylori eradication. Although the molecular me... Read more »

Effects of developmental lead exposure on the hippocampal methylome...
Published: March, 2018

Abstract: Developmental lead (Pb) exposure results in persistent cognitive/behavioral impairments as well as an elevated risk for developing a variety of dis... Read more »

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IP-Star Compact

Histone Deacetylases 1 and 2 Regulate Microglia Function during Dev...
Published: March, 2018

Abstract: Microglia as tissue macrophages contribute to the defense and maintenance of central nervous system (CNS) homeostasis. Little is known about the ep... Read more »

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True MicroChIP kit

EWS-FLI1 increases transcription to cause R-loops and block BRCA1 r...
Published: March, 2018

Abstract: Ewing sarcoma is an aggressive paediatric cancer of the bone and soft tissue. It results from a chromosomal translocation, predominantly t(11;22)(q... Read more »

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Microplex Library Preparation kit

Analysis of Meiotic Double-Strand Break Initiation in Mammals
Published: March, 2018

Abstract: The repair of programmed DNA double-strand breaks (DSBs) physically tethers homologous chromosomes in meiosis t... Read more »

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Bioruptor

A Specific PfEMP1 Is Expressed in P. falciparum Sporozoites and Pla...
Published: March, 2018

Abstract: Heterochromatin plays a central role in the process of immune evasion, pathogenesis, and transmission of the malaria parasite Plasmodium falciparum... Read more »

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Antibody Microplex Library Preparation kit

Corticosteroid receptors adopt distinct cyclical transcriptional si...
Published: March, 2018

Abstract: Mineralocorticoid receptors (MRs) and glucocorticoid receptors (GRs) are two closely related hormone-activated transcription factors that regulate ... Read more »

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ChIP-seq

Corticosteroid receptors adopt distinct cyclical transcriptional si...
Published: March, 2018

Abstract: Mineralocorticoid receptors (MRs) and glucocorticoid receptors (GRs) are two closely related hormone-activated transcription factors that regulate ... Read more »

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ChIP-seq

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