Publications,References

Jarid2 binds mono-ubiquitylated H2A lysine 119 to mediate crosstalk...
Published: November, 2016

Abstract: The Polycomb repressive complexes PRC1 and PRC2 play a central role in developmental gene regulation in multicellular organisms. PRC1 and PRC2 modi... Read more »

Tags
Antibody

Gene regulatory networks in neural cell fate acquisition from genom...
Published: November, 2016

Abstract: Neural cell fate acquisition is mediated by transcription factors expressed in nascent neuroectoderm, including Geminin and members of the Zic tran... Read more »

Tags
Antibody

Genome-wide epigenomic profiling for biomarker discovery
Published: November, 2016

Abstract: A myriad of diseases is caused or characterized by alteration of epigenetic patterns, including changes in DNA methylation, post-translational hist... Read more »

Tags
IP-Star Compact

Genome-wide DNA methylation analysis identifies MEGF10 as a novel e...
Published: November, 2016

Abstract: Neuroblastoma is a childhood cancer in which many children still have poor outcomes, emphasising the need to better understand its pathogenesis. De... Read more »

TET-dependent regulation of retrotransposable elements in mouse emb...
Published: November, 2016

Abstract: BACKGROUND: Ten-eleven translocation (TET) enzymes oxidise DNA methylation as part of an active demethylation pathway. Despite extensive researc... Read more »

Tags
Bioruptor Antibody

Genetic Drivers of Epigenetic and Transcriptional Variation in Huma...
Published: November, 2016

Abstract: Characterizing the multifaceted contribution of genetic and epigenetic factors to disease phenotypes is a major challenge in human genetics a... Read more »

Tags
Antibody IP-Star Compact

β-Glucan Reverses the Epigenetic State of LPS-Induced Immunological...
Published: November, 2016

Abstract: Innate immune memory is the phenomenon whereby innate immune cells such as monocytes or macrophages undergo functional reprogramming after exposure... Read more »

Tags
Bioruptor Antibody

EPOP Functionally Links Elongin and Polycomb in Pluripotent Stem Cells
Published: November, 2016

Abstract: The cellular plasticity of pluripotent stem cells is thought to be sustained by genomic regions that display both active and repressive chromatin p... Read more »

Tags
Bioruptor Antibody

Genome-wide DNA promoter methylation and transcriptome analysis in ...
Published: November, 2016

Abstract: Objective/methods DNA methylation plays an important role in obesity and related metabolic complications. We examined genome-wide DNA promoter met... Read more »

Tags
Bioruptor MagMeDIP kit

The Hematopoietic Transcription Factors RUNX1 and ERG Prevent AML1-...
Published: November, 2016

Abstract: The t(8;21) acute myeloid leukemia (AML)-associated oncoprotein AML1-ETO disrupts normal hematopoietic differentiation. Here, we have investigated ... Read more »

Tags
Bioruptor Antibody

Activation of GPER suppresses migration and angiogenesis of triple ...
Published: November, 2016

Abstract: Triple-negative breast cancer (TNBC) are characterized by high vascularity and frequent metastasis. Here, we found that activation of G protein-cou... Read more »

Reader domain specificity and lysine demethylase-4 family function
Published: November, 2016

Abstract: The KDM4 histone demethylases are conserved epigenetic regulators linked to development, spermatogenesis and tumorigenesis. However, how the KDM4 f... Read more »

Tags
Antibody

Enhanced CRISPR/Cas9-mediated precise genome editing by improved de...
Published: November, 2016

Abstract: While CRISPR-based gene knock out in mammalian cells has proven to be very efficient, precise insertion of genetic elements via the cellular homolo... Read more »

Tags
Antibody

Biphasic regulation of chondrocytes by Rela through induction of an...
Published: November, 2016

Abstract: In vitro studies have shown that Rela/p65, a key subunit mediating NF-κB signalling, is involved in chondrogenic differentiation, cell surviv... Read more »

TET2 binds the androgen receptor and loss is associated with prosta...
Published: November, 2016

Abstract: Genetic alterations associated with prostate cancer (PCa) may be identified by sequencing metastatic tumour genomes to identify molecular markers a... Read more »

Tags
Antibody

A set of novel automated quantitative microproteomics protocols for...
Published: November, 2016

Abstract: Here we assessed the ability of an automated sample preparation device equipped with disposable microcolumns to prepare mass-limited samples for hi... Read more »

Tags
Bioruptor Mass Spectrometry

Transcriptional Activation of Pericentromeric Satellite Repeats and...
Published: November, 2016

Abstract: Heterochromatinisation of pericentromeres, which in mice consist of arrays of major satellite repeats, are important for centromere formation and m... Read more »

Tags
Bioruptor IPure kit

Chromatin Preparation and Chromatin Immuno-precipitation from Droso...
Published: November, 2016

Abstract: This protocol provides specific details on how to perform Chromatin immunoprecipitation (ChIP) from Drosophila embryos. ChIP allows the matching of... Read more »

Tags
Antibody

Iterative Fragmentation Improves the Detection of ChIP-seq Peaks fo...
Published: October, 2016

Abstract: As chromatin immunoprecipitation (ChIP) sequencing is becoming the dominant technique for studying chromatin modifications, new protocols surface t... Read more »

Tags
Bioruptor Antibody

Genetic variation at the 8q24.21 renal cancer susceptibility locus ...
Published: October, 2016

Abstract: Clear cell renal cell carcinoma (ccRCC) is characterized by loss of function of the von Hippel-Lindau tumour suppressor (VHL) and unrestrained acti... Read more »

Tags
Bioruptor Antibody

DNA methylation and alcohol use disorders: Progress and challenges
Published: October, 2016

Abstract: Background and Objectives Risk for alcohol use disorders (AUDs) is influenced by gene–environment interactions. Environmental factors can ... Read more »

Tags
Premium RRBS Kit

Analysis of Cohesin Function in Gene Regulation and Chromatin Organ...
Published: October, 2016

Abstract: Cohesin is essential for the maintenance of chromosomes through the cell cycle. In addition, cohesin contributes to the regulation of gene expressi... Read more »

Foxo3 Transcription Factor Drives Pathogenic T Helper 1 Differentia...
Published: October, 2016

Abstract: The transcription factor Foxo3 plays a crucial role in myeloid cell function but its role in lymphoid cells remains poorly defined. Here, we have s... Read more »

Chronic stress leads to epigenetic dysregulation in the neuropeptid...
Published: October, 2016

Abstract: Persistent stress triggers a variety of mechanisms, which may ultimately lead to the occurrence of anxiety- and depression-related disorders. Epige... Read more »

Tags
Antibody

Regulation of transcriptional elongation in pluripotency and cell d...
Published: October, 2016

Abstract: Pluripotent embryonic stem cells (ESCs) self-renew or differentiate into all tissues of the developing embryo and cell-specification factors are ne... Read more »

Tags
Antibody

In vivo conditional deletion of HDAC7 reveals its requirement to es...
Published: October, 2016

Abstract: Class IIa histone deacetylase (HDAC) subfamily members are tissue-specific gene repressors with crucial roles in development and differentiation pr... Read more »

Tags
LowCell ChIP kit True MicroChIP kit

Zeb2 Regulates Cell Fate at the Exit from Epiblast State in Mouse E...
Published: October, 2016

Abstract: In human ESCs the transcription factor Zeb2 regulates neuroectoderm versus mesendoderm formation, but it is unclear how Zeb2 affects the global tra... Read more »

Tags
Premium RRBS Kit

DNA fragmentation and quality control analysis
Published: September, 2016

Abstract: Optimal data generation using NGS platforms relies on a few sample-preparation prerequisites, namely, precise DNA fragmentation, size-range an... Read more »

Tags
DNA shearing Bioruptor

The lncRNA landscape of breast cancer reveals a role for DSCAM-AS1 ...
Published: September, 2016

Abstract: Molecular classification of cancers into subtypes has resulted in an advance in our understanding of tumour biology and treatment response across m... Read more »

Tags
HighCell ChIP kit IPure kit

Novel regional age-associated DNA methylation changes within human ...
Published: September, 2016

Abstract: BACKGROUND: Advancing age progressively impacts on risk and severity of chronic disease. It also modifies the epigenome, with changes in DNA met... Read more »

Tags
MagMeDIP kit 5mC (C15200081)

Publications

活动