Publications,References

Deficient expression of JMJD1A histone demethylase in patients with...
Published: September, 2016

Abstract: JMJD1A (jumonji domain-containing 1A), a known histone H3K9 demethylase, has been identified as a critical epigenetic regulator in male germ cells,... Read more »

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Histone ChIP kit

Inheritable Silencing of Endogenous Genes by Hit-and-Run Targeted E...
Published: September, 2016

Abstract: Gene silencing is instrumental to interrogate gene function and holds promise for therapeutic applications. Here, we repurpose the endogenous retro... Read more »

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Bioruptor MagMeDIP kit IPure kit

Trichloroethylene-Induced DNA Methylation Changes in Male F344 Rat ...
Published: September, 2016

Abstract: Trichloroethylene (TCE), a common environmental contaminant, causes hepatocellular carcinoma in mice but not in rats. To understand the mechanisms ... Read more »

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MagMeDIP kit

Neonatal monocytes exhibit a unique histone modification landscape
Published: September, 2016

Abstract: Background Neonates have dampened expression of pro-inflammatory cytokines and difficulty clearing pathogens. This makes them uniquely susceptib... Read more »

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Antibody

BRD4 localization to lineage-specific enhancers is associated with ...
Published: September, 2016

Abstract: Proper temporal epigenetic regulation of gene expression is essential for cell fate determination and tissue development. The Bromodomain-containin... Read more »

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Antibody Microplex Library Preparation kit

Coordinate redeployment of PRC1 proteins suppresses tumor formation...
Published: September, 2016

Abstract: Polycomb group proteins form two main complexes, PRC2 and PRC1, which generally coregulate their target genes. Here we show that PRC1 components ac... Read more »

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Antibody

Overexpression of histone demethylase Fbxl10 leads to enhanced migr...
Published: September, 2016

Abstract: Cell migration is a central process in the development and maintenance of multicellular organisms. Tissue formation during embryonic development, w... Read more »

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Antibody

CTCF modulates Estrogen Receptor function through specific chromati...
Published: September, 2016

Abstract: Enhancer regions and transcription start sites of estrogen-target regulated genes are connected by means of Estrogen Receptor long-range chromatin ... Read more »

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Microplex Library Preparation kit

Heterochromatic histone modifications at transposons in Xenopus tro...
Published: September, 2016

Abstract: Transposable elements are parasitic genomic elements that can be deleterious for host gene function and genome integrity. Heterochromatic histone m... Read more »

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Antibody

Allelic reprogramming of the histone modification H3K4me3 in early ...
Published: September, 2016

Abstract: Histone modifications are fundamental epigenetic regulators that control many crucial cellular processes1. However, whether these marks can be pass... Read more »

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Antibody

Detection of Protein-Protein Interactions and Posttranslational Mod...
Published: September, 2016

Abstract: The detection of protein-protein interactions by imaging techniques often requires the overexpression of the proteins of interest tagged with fluor... Read more »

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Antibody

Condition-dependent co-regulation of genomic clusters of virulence ...
Published: September, 2016

Abstract: The ascomycete Neofusicoccum parvum, one of the causal agents of Botryosphaeria dieback, is a destructive wood-infecting fungus and a serious threa... Read more »

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Megaruptor

Esrrb directly binds to Gata6 promoter and regulates its expression...
Published: September, 2016

Abstract: Estrogen-related receptor beta (Esrrb) is expressed in embryonic stem (ES) cells and is involved in self-renewal ability and pluripotency. Previous... Read more »

Evolutionary Consequences of DNA Methylation in a Basal Metazoan.
Published: September, 2016

Abstract: Gene body methylation (gbM) is an ancestral and widespread feature in Eukarya, yet its adaptive value and evolutionary implications remain unresolv... Read more »

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MethylCap

Fumarate is an epigenetic modifier that elicits epithelial-to-mesen...
Published: August, 2016

Abstract: Mutations of the tricarboxylic acid cycle enzyme fumarate hydratase cause hereditary leiomyomatosis and renal cell cancer1. Fumarate hydratase-defi... Read more »

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Antibody

Chromatin remodeling regulates catalase expression during cancer ce...
Published: August, 2016

Abstract: Regulation of ROS metabolism plays a major role in cellular adaptation to oxidative stress in cancer cells, but the molecular mechanism that regula... Read more »

PionX sites mark the X chromosome for dosage compensation
Published: August, 2016

Abstract: The rules defining which small fraction of related DNA sequences can be selectively bound by a transcription factor are poorly understood. One of t... Read more »

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Microplex Library Preparation kit

Noncoding somatic and inherited single-nucleotide variants converge...
Published: August, 2016

Abstract: Sustained expression of the estrogen receptor-α (ESR1) drives two-thirds of breast cancer and defines the ESR1-positive subtype. ESR1 engages... Read more »

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Antibody

Remodelling of the hepatic epigenetic landscape of glucose-intolera...
Published: August, 2016

Abstract: The rainbow trout, a carnivorous fish, displays a ‘glucose-intolerant’ phenotype revealed by persistent hyperglycaemia when fed a high ... Read more »

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Antibody

Dynamic Interplay between the Transcriptome and Methylome in Respon...
Published: August, 2016

Abstract: In recent years, it has been shown that free radicals not only react directly with DNA but also regulate epigenetic processes such as DNA methylati... Read more »

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MagMeDIP kit IPure kit

H3.3 demarcates GC-rich coding and subtelomeric regions and serves ...
Published: August, 2016

Abstract: Histones, by packaging and organizing the DNA into chromatin, serve as essential building blocks for eukaryotic life. The basic structure of the ch... Read more »

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Antibody

Clinical, Imaging, Histopathological and Molecular Characterization...
Published: August, 2016

Abstract: Anaplastic ganglioglioma (AGG) is a rare and malignant variant of ganglioglioma. According to the World Health Organization classification version ... Read more »

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Antibody

The Development of a Viral Mediated CRISPR/Cas9 System with Doxycyc...
Published: August, 2016

Abstract: The RNA-guided Cas9 nuclease, from the type II prokaryotic Clustered Regularly Interspersed Short Palindromic Repeats (CRISPR) adaptive immune syst... Read more »

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Antibody

reChIP-seq reveals widespread bivalency of H3K4me3 and H3K27me3 in ...
Published: August, 2016

Abstract: The combinatorial action of co-localizing chromatin modifications and regulators determines chromatin structure and function. However, identifying ... Read more »

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Antibody Bioruptor Plus Microplex Library Preparation kit

HDAC1 negatively regulates Bdnf and Pvalb required for parvalbumin ...
Published: August, 2016

Abstract: During early postnatal development, neuronal circuits are sculpted by sensory experience provided by the external environment. This experience-depe... Read more »

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Antibody

Anti-RAINBOW dye-specific antibodies as universal tools for the vis...
Published: August, 2016

Abstract: Western blotting is one of the most widely used techniques in molecular biology and biochemistry. Prestained proteins are used as molecular weight ... Read more »

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Antibody

Polycomb repressive complex 2 (PRC2) silences genes responsible for...
Published: August, 2016

Abstract: Normal brain function depends on the interaction between highly specialized neurons that operate within anatomically and functionally distinct brai... Read more »

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LowCell ChIP kit

Phenotypic Plasticity through Transcriptional Regulation of the Evo...
Published: August, 2016

Abstract: Phenotypic plasticity is the ability of a given genotype to produce different phenotypes in response to distinct environmental conditions. Phenotyp... Read more »

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Antibody IPure kit

Ordered chromatin changes and human X chromosome reactivation by ce...
Published: August, 2016

Abstract: Erasure of epigenetic memory is required to convert somatic cells towards pluripotency. Reactivation of the inactive X chromosome (Xi) has been use... Read more »

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Antibody

MEF2C protects bone marrow B-lymphoid progenitors during stress hae...
Published: August, 2016

Abstract: DNA double strand break (DSB) repair is critical for generation of B-cell receptors, which are pre-requisite for B-cell progenitor survival. Howeve... Read more »

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Antibody

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