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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

NF-kB and c-Jun induce the expression of the oncogenic miR-221 and ...
Published: May, 2011
Abstract: MicroRNAs (miRNAs) are potent negative regulators of gene expression involved in all aspects of cell biology. They finely modulate virtually all ph... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Functional analysis of KAP1 genomic recruitment.
Published: May, 2011
Abstract: TRIM28 (KAP1) is upregulated in many cancers and has been implicated in both transcriptional activation and repression. Using chromatin immunopreci... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
JAG2 induction in hypoxic tumor cells alters Notch signaling and en...
Published: May, 2011
Abstract: Several studies have revealed links between hypoxia and activation of Notch in solid tumors. While most reports have focused on intracellular domai... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Mechanism of 1α,25-dihydroxyvitamin D(3)-dependent repression of in...
Published: May, 2011
Abstract: Interleukin 12 (IL-12) is a heterodimeric, pro-inflammatory cytokine that plays a central role in activation and differentiation of CD4(+) T cells ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Aryl hydrocarbon receptor ligands of widely different toxic equival...
Published: May, 2011
Abstract: Posttranslational histone modifications are a critical regulatory mechanism of gene transcription. Previous studies from our laboratory have shown ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The histone demethylase JARID1A regulates progesterone receptor exp...
Published: May, 2011
Abstract: Transcriptional control of the progesterone receptor gene by estrogen is a complex mechanism. It involves estrogen receptor α which uses several en... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Selective genomic targeting by FRA-2/FOSL2 transcription factor: re...
Published: April, 2011
Abstract: FRA-2/FOSL2 is a basic region-leucine zipper motif transcription factor that is widely expressed in mammalian tissues. The functional repertoire of... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Chromatin-modifying agents promote the ex vivo production of functi...
Published: April, 2011
Abstract: Presently, blood transfusion products (TPs) are composed of terminally differentiated cells with a finite life span. We have developed an ex vivo-g... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Widespread negative response elements mediate direct repression by ...
Published: April, 2011
Abstract: The glucocorticoid (GC) receptor (GR), when liganded to GC, activates transcription through direct binding to simple (+)GRE DNA binding sequences (... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Coordinated cancer germline antigen promoter and global DNA hypomet...
Published: April, 2011
Abstract: PURPOSE: Cancer germline (CG) antigens are frequently expressed and hypomethylated in epithelial ovarian cancer (EOC), but the relationship of this... Read more »
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Bioruptor Western Blot Tissue Homogenization
Genome-wide analysis of target genes regulated by HoxB4 in hematopo...
Published: April, 2011
Abstract: Forced expression of the transcription factor HoxB4 has been shown to enhance the self-renewal capacity of mouse bone marrow hematopoietic stem cel... Read more »
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Chromatin Shearing ChIP-qPCR
Tumour evolution inferred by single-cell sequencing.
Published: April, 2011
Abstract: Genomic analysis provides insights into the role of copy number variation in disease, but most methods are not designed to resolve mixed population... Read more »
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DNA shearing Bioruptor
TLE3 is a dual-function transcriptional coregulator of adipogenesis.
Published: April, 2011
Abstract: PPARγ and Wnt signaling are central positive and negative regulators of adipogenesis, respectively. Here we identify the groucho family member TLE3... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Master Mix
Replication stress induces 53BP1-containing OPT domains in G1 cells.
Published: April, 2011
Abstract: Chromosomal deletions and rearrangements in tumors are often associated with common fragile sites, which are specific genomic loci prone to gaps an... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Tracing the domestication of a biofilm-forming bacterium.
Published: April, 2011
Abstract: Over the course of more than a century of laboratory experimentation, Bacillus subtilis has become "domesticated," losing its ability to carry out ... Read more »
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DNA shearing Bioruptor
New role for granulocyte colony-stimulating factor-induced extracel...
Published: April, 2011
Abstract: The induction of the granulocytic differentiation of leukemic cells by all-trans retinoic acid (RA) has been a major breakthrough in terms of survi... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Regulation of mouse embryonic stem cell self-renewal by a Yes-YAP-T...
Published: April, 2011
Abstract: The cytoplasmic tyrosine kinase Yes has previously been shown to have an important role in maintaining mouse and human embryonic stem (ES) self-ren... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody
The chromodomains of CHD1 are critical for enzymatic activity but l...
Published: April, 2011
Abstract: The molecular motor protein CHD1 has been implicated in the regulation of transcription and in the transcription-independent genome-wide incorporat... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Epigenetic switch involved in activation of pioneer factor FOXA1-de...
Published: April, 2011
Abstract: Transcription factors (TFs) bind specifically to discrete regions of mammalian genomes called cis-regulatory elements. Among those are enhancers, w... Read more »
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DNA shearing Bioruptor Chromatin Shearing ChIP-qPCR Antibody
HDAC-mediated deacetylation of NF-κB is critical for Schwann cell m...
Published: April, 2011
Abstract: Schwann cell myelination is tightly regulated by timely expression of key transcriptional regulators that respond to specific environmental cues, b... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The Bin3 RNA methyltransferase is required for repression of caudal...
Published: April, 2011
Abstract: Bin3 was first identified as a Bicoid-interacting protein in a yeast two-hybrid screen. In human cells, a Bin3 ortholog (BCDIN3) methylates the 5' ... Read more »
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Bioruptor
Psm3 acetylation on conserved lysine residues is dispensable for vi...
Published: April, 2011
Abstract: In budding yeast and humans, cohesion establishment during S phase requires the acetyltransferase Eco1/Esco1-2, which acetylates the cohesin subuni... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Genome-wide analysis of 5-hydroxymethylcytosine distribution reveal...
Published: April, 2011
Abstract: Recent studies have demonstrated that the Ten-eleven translocation (Tet) family proteins can enzymatically convert 5-methylcytosine (5mC) to 5-hydr... Read more »
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Antibody
Heterochromatin formation in bistable chromatin domains controls th...
Published: April, 2011
Abstract: Clonally variant gene expression is a common survival strategy used by many pathogens, including the malaria parasite Plasmodium falciparum. Among ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Recombineering, transfection, Western, IP and ChIP methods for prot...
Published: April, 2011
Abstract: Protein tagging offers many advantages for proteomic and regulomic research. Ideally, protein tagging is equivalent to having a high affinity antib... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Cell Lysis Western Blot Antibody
Epigenetic Regulation of Glucose Transporters in Non-Small Cell Lun...
Published: March, 2011
Abstract: Due to their inherently hypoxic environment, cancer cells often resort to glycolysis, or the anaerobic breakdown of glucose to form ATP to provide ... Read more »
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Antibody H3K4me3 (C15410003)
Comprehensive analysis of the chromatin landscape in Drosophila mel...
Published: March, 2011
Abstract: Chromatin is composed of DNA and a variety of modified histones and non-histone proteins, which have an impact on cell differentiation, gene regula... Read more »
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Bioruptor Chromatin Shearing
Biparental inheritance of chromosomal abnormalities in male twins w...
Published: March, 2011
Abstract: In a monozygotic twin couple with mental retardation (MR), we identified a maternally inherited inversion and a paternally inherited translocation:... Read more »
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DNA shearing Bioruptor
Direct recruitment of ERK cascade components to inducible genes is ...
Published: March, 2011
Abstract: Components of the ERK cascade are recruited to genes, but it remains unknown how they are regulated at these sites. The RNA-binding protein heterog... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Regulation of the PMP22 gene through an intronic enhancer.
Published: March, 2011
Abstract: Successful myelination of the peripheral nervous system depends upon induction of major protein components of myelin, such as peripheral myelin pro... Read more »
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Bioruptor Chromatin Shearing

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