Publications,References

Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in...
Published: December, 2010

Abstract: Epidermal and hair follicle development from surface ectodermal progenitor cells requires coordinated changes in gene expression. Histone deacetyla... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Histone H2A C-terminus regulates chromatin dynamics, remodeling, an...
Published: December, 2010

Abstract: The tails of histone proteins are central players for all chromatin-mediated processes. Whereas the N-terminal histone tails have been studied exte... Read more »

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Antibody

ZNF274 recruits the histone methyltransferase SETDB1 to the 3' ends...
Published: December, 2010

Abstract: Only a small percentage of human transcription factors (e.g. those associated with a specific differentiation program) are expressed in a given cel... Read more »

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Bioruptor Chromatin Shearing ChIP-seq Antibody

Control of the differentiation of regulatory T cells and T(H)17 cel...
Published: December, 2010

Abstract: The molecular mechanisms that direct transcription of the gene encoding the transcription factor Foxp3 in CD4(+) T cells remain ill-defined. We sho... Read more »

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Antibody

Targets and dynamics of promoter DNA methylation during early mouse...
Published: December, 2010

Abstract: DNA methylation is extensively reprogrammed during the early phases of mammalian development, yet genomic targets of this process are largely unkno... Read more »

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DNA shearing Bioruptor

Quality control and single nucleotide resolution analysis of methyl...
Published: December, 2010

Abstract: DNA methylation patterns are altered in many diseases, and their analysis has become of great interest. Methylated DNA immunoprecipitation (MeDIP) ... Read more »

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DNA shearing Bioruptor IP-Star

STAT6 transcription factor is a facilitator of the nuclear receptor...
Published: November, 2010

Abstract: Peroxisome proliferator-activated receptor γ (PPARγ) is a lipid-activated transcription factor regulating lipid metabolism and inflammatory respons... Read more »

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Antibody

Evidence for a dynamic role of the linker histone variant H1x durin...
Published: November, 2010

Abstract: The dynamics of chromatin structure are tightly regulated by multiple epigenetic mechanisms such as histone modifications and incorporation of hist... Read more »

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Histone ChIP kit

Multiplexed DNA sequence capture of mitochondrial genomes using PCR...
Published: November, 2010

Abstract: BACKGROUND: To utilize the power of high-throughput sequencers, target enrichment methods have been developed. The majority of these require reagen... Read more »

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DNA shearing Bioruptor

PRDM1/Blimp-1 controls effector cytokine production in human NK cells.
Published: November, 2010

Abstract: NK cells are major effectors of the innate immune response through cytolysis and bridge to the adaptive immune response through cytokine release. T... Read more »

Transcriptional regulation of ROS controls transition from prolifer...
Published: November, 2010

Abstract: The balance between cellular proliferation and differentiation is a key aspect of development in multicellular organisms. Using high-resolution exp... Read more »

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Bioruptor Chromatin Shearing

A model for neural development and treatment of Rett syndrome using...
Published: November, 2010

Abstract: Autism spectrum disorders (ASD) are complex neurodevelopmental diseases in which different combinations of genetic mutations may contribute to the ... Read more »

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Antibody

Transcription factor IIS impacts UV-inhibited transcription.
Published: November, 2010

Abstract: Inhibition of transcription elongation can cause severe developmental and neurological abnormalities notably manifested by the rare recessive proge... Read more »

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Bioruptor Cell Lysis Western Blot

Loss of H3 K79 trimethylation leads to suppression of Rtt107-depend...
Published: November, 2010

Abstract: Genomic integrity is maintained by the coordinated interaction of many DNA damage response pathways, including checkpoints, DNA repair processes, a... Read more »

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DNA shearing Bioruptor

Whole genome DNA methylation analysis based on high throughput sequ...
Published: November, 2010

Abstract: There are numerous approaches to decipher a whole genome DNA methylation profile ("methylome"), each varying in cost, throughput and resolution. Th... Read more »

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MagMeDIP kit

Whole-genome DNA methylation profiling using MethylCap-seq.
Published: November, 2010

Abstract: MethylCap-seq is a robust procedure for genome-wide profiling of DNA methylation. The approach consists of the capture of methylated DNA using the ... Read more »

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DNA shearing Bioruptor IP-Star

High-resolution whole-genome sequencing reveals that specific chrom...
Published: November, 2010

Abstract: The nuclear space is mostly occupied by chromosome territories and nuclear bodies. Although this organization of chromosomes affects gene function,... Read more »

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DNA shearing Bioruptor

Epigenetic silencing of spermatocyte-specific and neuronal genes by...
Published: November, 2010

Abstract: SUMO modification of transcription factors is linked to repression of transcription. The physiological significance of SUMO attachment to a particu... Read more »

Low doses of the carcinogen furan alter cell cycle and apoptosis ge...
Published: November, 2010

Abstract: BACKGROUND: Evidence of potent rodent carcinogenicity via an unclear mechanism suggests that furan in various foods [leading to an intake of up to ... Read more »

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MagMeDIP kit

Glucocorticoid receptor regulates overlapping and differential gene...
Published: November, 2010

Abstract: We have previously shown that the glucocorticoid receptor (GR) is required for skin homeostasis and epidermal barrier competence. To understand the... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Histone modifications at the blastocyst Axin1(Fu) locus mark the he...
Published: November, 2010

Abstract: For epigenetic phenotypes to be passed on from one generation to the next, it is required that epigenetic marks between generations are not cleared... Read more »

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Antibody LowCell ChIP kit

Transcriptional profiling by deep sequencing identifies differences...
Published: November, 2010

Abstract: In vitro embryo culture systems promote development at rates lower than in vivo systems. The goal of this project was to discover transcripts that ... Read more »

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DNA shearing Bioruptor

The histone H4 Lys 20 methyltransferase PR-Set7 regulates replicati...
Published: November, 2010

Abstract: The initiation of DNA synthesis is governed by the licensing of replication origins, which consists of assembling a pre-replication complex (pre-RC... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Antibody

Expression of MUC5AC, an early marker of pancreatobiliary cancer, i...
Published: November, 2010

Abstract: BACKGROUND AND PURPOSE: High de novo expression of MUC5AC (a gastric-type secreted mucin) is observed in many types of pancreatobiliary neoplasms, ... Read more »

An intronic enhancer driven by NF-κB contributes to transcriptional...
Published: November, 2010

Abstract: Peptidylarginine deiminases (PADs) catalyze the conversion of protein-bound arginine to citrulline residues. In human epidermis, where filaggrin is... Read more »

Nucleosome-interacting proteins regulated by DNA and histone methyl...
Published: October, 2010

Abstract: Modifications on histones or on DNA recruit proteins that regulate chromatin function. Here, we use nucleosomes methylated on DNA and on histone H3... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Promoter-exon relationship of H3 lysine 9, 27, 36 and 79 methylatio...
Published: October, 2010

Abstract: Evidence links pluripotency to a gene regulatory network organized by the transcription factors Oct4, Nanog and Sox2. Expression of these genes is ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Antibody

Cell cycle-dependent accumulation of histone H3.3 and euchromatic h...
Published: October, 2010

Abstract: In mammals, DNA methylation is an important epigenetic mark that is associated with gene silencing, particularly in constitutive heterochromatin. H... Read more »

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Chromatin Shearing ChIP-qPCR

ETV1 is a lineage survival factor that cooperates with KIT in gastr...
Published: October, 2010

Abstract: Gastrointestinal stromal tumour (GIST) is the most common human sarcoma and is primarily defined by activating mutations in the KIT or PDGFRA recep... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Combinatorial transcriptional control in blood stem/progenitor cell...
Published: October, 2010

Abstract: Combinatorial transcription factor (TF) interactions control cellular phenotypes and, therefore, underpin stem cell formation, maintenance, and dif... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

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