Publications,References

Alu retrotransposons modulate Nanog expression through dynamic chan...
Published: March, 2020

Abstract: Transcriptional repression of Nanog is an important hallmark of stem cell differentiation. Chromatin modifications have been linked to the epigenet... Read more »

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Antibody

Anti-adipogenic signals at the onset of obesity-related inflammatio...
Published: March, 2020

Abstract: Chronic inflammation that affects primarily metabolic organs, such as white adipose tissue (WAT), is considered as a major cause of human obesity-a... Read more »

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Microplex Library Preparation kit

LXR Activation Induces a Proinflammatory Trained Innate Immunity-Ph...
Published: March, 2020

Abstract: The concept of trained innate immunity describes a long-term proinflammatory memory in innate immune cells. Trained innate immunity is regulated th... Read more »

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Antibody

LY75 Ablation Mediates Mesenchymal-Epithelial Transition (MET) in E...
Published: March, 2020

Abstract: Growing evidence demonstrates that epithelial-mesenchymal transition (EMT) plays an important role in epithelial ovarian cancer (EOC) progression a... Read more »

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DNA Methylation Profiling (RRBS Service)

CDK7 Inhibition is Effective in all the Subtypes of Breast Cancer: ...
Published: March, 2020

Abstract: CDK7, a transcriptional cyclin-dependent kinase, is emerging as a novel cancer target. Triple-negative breast cancers (TNBC) but not estrogen recep... Read more »

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Antibody

Genome-wide DNA Methylation Analysis of Mantle Edge and Mantle Cent...
Published: March, 2020

Abstract: DNA methylation is a type of epigenetic modification that alters gene expression without changing the DNA sequence and mediates some cases of pheno... Read more »

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MagMeDIP kit

Dnmt3a and Dnmt3b-Decommissioned Fetal Enhancers are Linked to Kidn...
Published: March, 2020

Abstract: BACKGROUND: Cytosine methylation is an epigenetic mark that dictates cell fate and response to stimuli. The timing and establishment of methylation... Read more »

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Premium RRBS Kit

ChromID identifies the protein interactome at chromatin marks.
Published: March, 2020

Abstract: Chromatin modifications regulate genome function by recruiting proteins to the genome. However, the protein composition at distinct chromatin modif... Read more »

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Antibody

Human cardiac fibrosis-on-a-chip model recapitulates disease hallma...
Published: March, 2020

Abstract: While interstitial fibrosis plays a significant role in heart failure, our understanding of disease progression in humans is limited. To address th... Read more »

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CATS

HDAC3 functions as a positive regulator in Notch signal transduction.
Published: February, 2020

Abstract: Aberrant Notch signaling plays a pivotal role in T-cell acute lymphoblastic leukemia (T-ALL) and chronic lymphocytic leukemia (CLL). Amplitude and ... Read more »

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Antibody Microplex Library Preparation kit

A MORC-driven transcriptional switch controls Toxoplasma developmen...
Published: February, 2020

Abstract: Toxoplasma gondii has a complex life cycle that is typified by asexual development that takes place in vertebrates, and sexual reproduction, which ... Read more »

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Antibody IPure kit iDeal ChIP-seq Kit for Histones Beads

Transferrin Receptor 1 Regulates Thermogenic Capacity and Cell Fate...
Published: February, 2020

Abstract: Iron homeostasis is essential for maintaining cellular function in a wide range of cell types. However, whether iron affects the thermogenic proper... Read more »

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Antibody True MicroChIP kit

Recombination may occur in the absence of transcription in the immu...
Published: February, 2020

Abstract: Developing B cells undergo V(D)J recombination to generate a vast repertoire of Ig molecules. V(D)J recombination is initiated by the RAG1/RAG2 com... Read more »

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Antibody Premium Bisulfite Kit

Alteration of CTCF-associated chromatin neighborhood inhibits TAL1-...
Published: February, 2020

Abstract: Aberrant activation of the TAL1 is associated with up to 60% of T-ALL cases and is involved in CTCF-mediated genome organization within the TAL1 lo... Read more »

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Antibody

DNA Methylation Editing by CRISPR-guided Excision of 5-Methylcytosine.
Published: February, 2020

Abstract: Tools for actively targeted DNA demethylation are required to increase our knowledge about regulation and specific functions of this important epig... Read more »

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Antibody CRISPR

STAT Signaling Modifies Ascl1 Chromatin Binding and Limits Neural R...
Published: February, 2020

Abstract: Müller glia (MG) serve as sources for retinal regeneration in non-mammalian vertebrates. We find that this process can be induced in mous... Read more »

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LowCell ChIP kit

LncRNA np_5318 promotes renal ischemia‑reperfusion injury through t...
Published: February, 2020

Abstract: Long noncoding (Lnc)RNA np_5318 has been proved to be involved in renal injury, while its functionality in renal ischemia‑reperfusion (I/R) injury ... Read more »

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iDeal ChIP-seq Kit for Transcription Factors

Widespread loss of the silencing epigenetic mark H3K9me3 in astrocy...
Published: February, 2020

Abstract: BACKGROUND: Hexanucleotide repeat expansions of the GC motif in a non-coding region of the C9ORF72 gene are the most common genetic cause of amyotr... Read more »

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Antibody

Rheumatoid Arthritis Patients, Both Newly Diagnosed and Methotrexat...
Published: February, 2020

Abstract: Rheumatoid arthritis (RA) is a chronic autoimmune disease that causes pain and swelling of multiple joints in the body. The underlying disease mech... Read more »

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Premium RRBS Kit

Seviteronel, a Novel CYP17 Lyase Inhibitor and Androgen Receptor An...
Published: February, 2020

Abstract: Increased rates of locoregional recurrence (LR) have been observed in triple negative breast cancer (TNBC) despite multimodality therapy, including... Read more »

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HighCell ChIP kit IPure kit

MYCN amplification and ATRX mutations are incompatible in neuroblas...
Published: February, 2020

Abstract: Aggressive cancers often have activating mutations in growth-controlling oncogenes and inactivating mutations in tumor-suppressor genes. In neurobl... Read more »

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iDeal ChIP-seq Kit for Histones

Inhibition of methyltransferase activity of enhancer of zeste 2 lea...
Published: February, 2020

Abstract: BACKGROUND: Recent studies indicate that exposure to environmental chemicals may increase susceptibility to developing metabolic diseases. This sus... Read more »

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Antibody

REDOX RESPONSIVE TRANSCRIPTION FACTOR1 (RRFT1) is involved in extra...
Published: February, 2020

Abstract: Extracellular ATP (eATP) is an apoplastic signaling molecule that plays essential roles in the growth and development of plants. Arabidopsis seedli... Read more »

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ChIP-seq

Targeting Macrophage Histone H3 Modification as a Leishmania Strate...
Published: February, 2020

Abstract: Aberrant macrophage activation during intracellular infection generates immunopathologies that can cause severe human morbidity. A better understan... Read more »

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Antibody

Smad anchor for receptor activation nuclear localization during dev...
Published: February, 2020

Abstract: Smad anchor for receptor activation (SARA, zfyve9) has been classically observed in early endosomes of different cells types where it regulates ves... Read more »

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ChIP-qPCR

Host-Specific Evolutionary and Transmission Dynamics Shape the Func...
Published: February, 2020

Abstract: Metagenomic inferences of bacterial strain diversity and infectious disease transmission studies largely assume a dominant, within-individual haplo... Read more »

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Megaruptor

Threonine phosphorylation of IκBζ mediates inhibition of selective ...
Published: February, 2020

Abstract: Transcription factors of the NF-κB family play a crucial role for immune responses by activating the expression of chemokines, cytokines and ... Read more »

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Antibody

Polycomb Group Proteins Regulate Chromatin Architecture in Mouse Oo...
Published: February, 2020

Abstract: In mammals, chromatin organization undergoes drastic reorganization during oocyte development. However, the dynamics of three-dimensional chromatin... Read more »

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Antibody

Long non-coding RNA uc.291 controls epithelial differentiation by i...
Published: February, 2020

Abstract: The mechanisms that regulate the switch between epidermal progenitor state and differentiation are not fully understood. Recent findings indicate t... Read more »

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Antibody

Tissue alarmins and adaptive cytokine induce dynamic and distinct t...
Published: February, 2020

Abstract: The respective effects of tissue alarmins interleukin (IL)-15 and interferon beta (IFNβ), and IL-21 produced by T cells on the reprogramming o... Read more »

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Antibody

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