Publications,References

Interleukin-22 protects intestinal stem cells against genotoxic str...
Published: February, 2019

Abstract: Environmental genotoxic factors pose a challenge to the genomic integrity of epithelial cells at barrier surfaces that separate host organisms from... Read more »

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Beads

Characterizing the Major Structural Variant Alleles of the Human Ge...
Published: January, 2019

Abstract: In order to provide a comprehensive resource for human structural variants (SVs), we generated long-read sequence data and analyzed SVs for fifteen... Read more »

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Megaruptor

Complete Genome Sequence and Methylome Analysis of Micrococcus lute...
Published: January, 2019

Abstract: Micrococcus luteus has been found in a wide range of habitats. We report the complete genome sequence and methylome analysis of strain SA211 isolat... Read more »

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Megaruptor

Replication timing and epigenome remodelling are associated with th...
Published: January, 2019

Abstract: DNA replication timing is known to facilitate the establishment of the epigenome, however, the intimate connection between replication timing and c... Read more »

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Antibody

Evidence of association of circulating epigenetic-sensitive biomark...
Published: January, 2019

Abstract: Circulating biomarkers available in clinical practice do not allow to stratify patients with coronary heart disease (CHD) prior the onset of a clin... Read more »

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MagMeDIP kit

Chromatin-Based Classification of Genetically Heterogeneous AMLs in...
Published: January, 2019

Abstract: Global investigation of histone marks in acute myeloid leukemia (AML) remains limited. Analyses of 38 AML samples through integrated transcriptiona... Read more »

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Antibody

CRISPR-mediated activation of a promoter or enhancer rescues obesit...
Published: January, 2019

Abstract: A wide range of human diseases result from haploinsufficiency, where the function of one of the two gene copies is lost. Here, we targeted the rema... Read more »

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CRISPR

High-throughput ChIPmentation: freely scalable, single day ChIPseq ...
Published: January, 2019

Abstract: BACKGROUND: Chromatin immunoprecipitation coupled to sequencing (ChIP-seq) is widely used to map histone modifications and transcription factor bin... Read more »

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Antibody

Retinoic Acid Receptor Alpha Represses a Th9 Transcriptional and Ep...
Published: January, 2019

Abstract: CD4 T helper (Th) differentiation is regulated by diverse inputs, including the vitamin A metabolite retinoic acid (RA). RA acts through its recept... Read more »

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Antibody

Comprehensive Analysis of Chromatin States in Atypical Teratoid/Rha...
Published: January, 2019

Abstract: Biallelic inactivation of SMARCB1, encoding a member of the SWI/SNF chromatin remodeling complex, is the hallmark genetic aberration of atypical te... Read more »

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Antibody

Hyper-Editing of Cell-Cycle Regulatory and Tumor Suppressor RNA Pro...
Published: January, 2019

Abstract: Adenosine deaminase associated with RNA1 (ADAR1) deregulation contributes to therapeutic resistance in many malignancies. Here we show that ADAR1-i... Read more »

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Antibody LowCell ChIP kit

Fluorescence-Activated Cell Sorting-Based Isolation and Characteriz...
Published: January, 2019

Abstract: Adult mammalian brain, including humans, has rather limited addition of new neurons and poor regenerative capacity. In contrast, neural stem cells ... Read more »

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Microplex Library Preparation kit

The Wnt-Driven Mll1 Epigenome Regulates Salivary Gland and Head and...
Published: January, 2019

Abstract: We identified a regulatory system that acts downstream of Wnt/β-catenin signaling in salivary gland and head and neck carcinomas. We show in a... Read more »

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Antibody iDeal ChIP-seq Kit for Histones iDeal Library Preparation Kit

LncRNA Dnmt3aos regulates Dnmt3a expression leading to aberrant DNA...
Published: January, 2019

Abstract: Long non-coding RNAs (lncRNAs) play key roles in various biological processes. However, the roles of lncRNAs in macrophage polarization remain larg... Read more »

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MagMeDIP kit

The histone methyltransferase DOT1L is required for proper DNA dama...
Published: January, 2019

Abstract: BACKGROUND: Disruptor of telomeric silencing 1-like (DOT1L) is a non-SET domain containing methyltransferase known to catalyze mono-, di-, and tri-... Read more »

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Antibody

Global distribution of DNA hydroxymethylation and DNA methylation i...
Published: January, 2019

Abstract: BACKGROUND: Chronic lymphocytic leukemia (CLL) has been a good model system to understand the functional role of 5-methylcytosine (5-mC) in cancer ... Read more »

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MagMeDIP kit Antibody

Optimization of CRISPR/Cas9 Delivery to Human Hematopoietic Stem an...
Published: January, 2019

Abstract: Editing the β-globin locus in hematopoietic stem cells is an alternative therapeutic approach for gene therapy of β-thalassemia and sickl... Read more »

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Antibody

Protocols for Genetic and Epigenetic Studies of Rare Diseases Affec...
Published: January, 2019

Abstract: This chapter describes methods related to the diagnosis of genetic dental diseases. Based on the present knowledge, clinical phenotyping and next-g... Read more »

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MagMeDIP kit IPure kit IP-Star Compact

Epigenetic Co-Deregulation of EZH2/TET1 is a Senescence-Countering,...
Published: January, 2019

Abstract: Triple-negative breast cancer (TNBC) cells lack the expression of ER, PR and HER2. Thus, TNBC patients cannot benefit from hormone receptor-targete... Read more »

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iDeal ChIP-seq Kit for Transcription Factors

Gamma radiation induces locus specific changes to histone modificat...
Published: January, 2019

Abstract: Ionizing radiation is a recognized genotoxic agent, however, little is known about the role of the functional form of DNA in these processes. Post ... Read more »

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Antibody

Identification of ChIP-seq and RIME grade antibodies for Estrogen R...
Published: January, 2019

Abstract: Estrogen Receptor alpha (ERα) plays a major role in most breast cancers, and it is the target of endocrine therapies used in the clinic as st... Read more »

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Antibody

Transcriptome-Wide Mapping 5-Methylcytosine by mC RNA Immunoprecipi...
Published: January, 2019

Abstract: Transcriptome-wide mapping RNA modification is crucial to understand the distribution and function of RNA modifications. Here, we describe a protoc... Read more »

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Antibody

Glucocorticoids stimulate hypothalamic dynorphin expression account...
Published: January, 2019

Abstract: Stress-induced reproductive dysfunction is frequently associated with increased glucocorticoid (GC) levels responsible for suppressed GnRH/LH secre... Read more »

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iDeal ChIP-seq Kit for Transcription Factors

Sensitivity of pituitary gonadotropes to hyperglycemia leads to epi...
Published: December, 2018

Abstract: The connection between metabolism and reproductive function is well recognized, and we hypothesized that the pituitary gonadotropes, which produce ... Read more »

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Antibody

DeltaNp63-dependent super enhancers define molecular identity in pa...
Published: December, 2018

Abstract: Molecular subtyping of cancer offers tremendous promise for the optimization of a precision oncology approach to anticancer therapy. Recent advance... Read more »

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Antibody Microplex Library Preparation kit

Reference genome for the WHO reference strain for Mycobacterium bov...
Published: December, 2018

Abstract: Mycobacterium bovis bacillus Calmette-Guérin (M. bovis BCG) is the only vaccine available against tuberculosis (TB). This study reports on a... Read more »

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Megaruptor

Mutant p63 Affects Epidermal Cell Identity through Rewiring the Enh...
Published: December, 2018

Abstract: Transcription factor p63 is a key regulator of epidermal keratinocyte proliferation and differentiation. Mutations in the p63 DNA-binding domain ar... Read more »

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Antibody

The Aryl Hydrocarbon Receptor Pathway Defines the Time Frame for Re...
Published: December, 2018

Abstract: Zebrafish have a high capacity to replace lost neurons after brain injury. New neurons involved in repair are generated by a specific set of glial ... Read more »

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Microplex Library Preparation kit

Plasmodium falciparum gametocyte-infected erythrocytes do not adher...
Published: December, 2018

Abstract: Plasmodium falciparum gametocytes, the sexual stages responsible for malaria parasite transmission, develop in the human bone marrow parenchyma in ... Read more »

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Antibody

Epigenetic suppression of E-cadherin expression by Snail2 during th...
Published: December, 2018

Abstract: BACKGROUND: The transcription factor Snail2 is a repressor of E-cadherin expression during carcinogenesis; however, the specific mechanisms involve... Read more »

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Antibody

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