Publications,References

Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by ...
Published: April, 2017

Abstract: The transcription factor Meis1 drives myeloid leukemogenesis in the context of Hox gene overexpression but is currently considered undruggable... Read more »

Tags
IPure kit

c-Myc Antagonises the Transcriptional Activity of the Androgen Rece...
Published: April, 2017

Abstract: Prostate cancer (PCa) is the most common non-cutaneous cancer in men. The androgen receptor (AR), a ligand-activated transcription factor, constitu... Read more »

Tags
ChIP-seq Antibody H3K4me3 (C15410003) H3K27ac (C15410174) H3K27me3 (C15410195)

Regulation of DNA demethylation by the XPC DNA repair complex in so...
Published: April, 2017

Abstract: Faithful resetting of the epigenetic memory of a somatic cell to a pluripotent state during cellular reprogramming requires DNA methylation to sile... Read more »

Tags
Antibody

Male fertility status is associated with DNA methylation signatures...
Published: April, 2017

Abstract: BACKGROUND: Infertility in dairy cattle is a concern where reduced fertilization rates and high embryonic loss are contributing factors. Studies... Read more »

Tags
MethylCap

The Rhomboid Protease GlpG Promotes the Persistence of Extraintesti...
Published: April, 2017

Abstract: Extraintestinal pathogenic Escherichia coli (ExPEC) strains are typically benign within the mammalian gut, but can disperse to extraintestina... Read more »

Tags
Bioruptor

Comparative analysis of MBD-seq and MeDIP-seq and estimation of gen...
Published: March, 2017

Abstract: We conducted a comparative study of multiplexed affinity enrichment sequence methodologies (MBD-seq and MeDIP-seq) in a rodent model of schizophren... Read more »

Tags
MagMeDIP kit MethylCap

The antiproliferative ELF2 isoform, ELF2B, induces apoptosis in vit...
Published: March, 2017

Abstract: Background ELF2 (E74-like factor 2) also known as NERF (new Ets-related factor), a member of the Ets family of transcription factors, regulates ... Read more »

Tags
Bioruptor

Epigenetically-driven anatomical diversity of synovial fibroblasts ...
Published: March, 2017

Abstract: A number of human diseases, such as arthritis and atherosclerosis, include characteristic pathology in specific anatomical locations. Here we show ... Read more »

Tags
Antibody Microplex Library Preparation kit

Microinjection of Antibodies Targeting the Lamin A/C Histone-Bindin...
Published: March, 2017

Abstract: Lamins form a scaffold lining the nucleus that binds chromatin and contributes to spatial genome organization; however, due to the many other funct... Read more »

Tags
Antibody

Epigenetically-driven anatomical diversity of synovial fibroblasts ...
Published: March, 2017

Abstract: A number of human diseases, such as arthritis and atherosclerosis, include characteristic pathology in specific anatomical locations. Here we show ... Read more »

Tags
ChIP-seq

JMJD3 aids in reprogramming of bone marrow progenitor cells to hepa...
Published: March, 2017

Abstract: The strictly regulated unidirectional differentiation program in some somatic stem/progenitor cells has been found to be modified in the ectopic si... Read more »

Tags
LowCell ChIP kit

Behavioral, transcriptomic and epigenetic responses to social chall...
Published: March, 2017

Abstract: Understanding how social experiences are represented in the brain and shape future responses is a major challenge in the study of behavior. We addr... Read more »

Tags
ChIP-seq

mTORC1 Promotes T-bet Phosphorylation To Regulate Th1 Differentiation
Published: March, 2017

Abstract: CD4+ T cells lacking the mTORC1 activator Rheb fail to secrete IFN-γ under Th1 polarizing conditions. We hypothesized that this phenotype is ... Read more »

Trimethylation and Acetylation of β-Catenin at Lysine 49 Represent ...
Published: March, 2017

Abstract: Wnt/β-catenin signaling is required for embryonic stem cell (ESC) pluripotency by inducing mesodermal differentiation and inhibiting neuronal ... Read more »

Tags
Antibody

Chd7 is indispensable for mammalian brain development through activ...
Published: March, 2017

Abstract: Mutations in chromatin modifier genes are frequently associated with neurodevelopmental diseases. We herein demonstrate that the chromodomain helic... Read more »

Tags
Antibody

Islet-1 induces the differentiation of mesenchymal stem cells into ...
Published: March, 2017

Abstract: Previous studies from this group demonstrated that insulin gene enhancer binding protein ISL-1 (Islet-1) specifically induces the differentiation o... Read more »

Tags
Bioruptor

Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of...
Published: March, 2017

Abstract: Methylation of lysine residues on histone tail is a dynamic epigenetic modification that plays a key role in chromatin structure and gene regulatio... Read more »

Tags
Antibody

Decoupling of DNA methylation and activity of intergenic LINE-1 pro...
Published: March, 2017

Abstract: Hypomethylation of LINE-1 repeats in cancer has been proposed as the main mechanism behind their activation; this assumption, however, was based on... Read more »

Tags
Antibody

miR-30a as Potential Therapeutics by Targeting TET1 through Regulat...
Published: March, 2017

Abstract: Several recent studies have indicated that miR-30a plays critical roles in various biological processes and diseases. However, the mechanism of miR... Read more »

Tags
Antibody

Functional variation in allelic methylomes underscores a strong gen...
Published: March, 2017

Abstract: BACKGROUND: The functional impact of genetic variation has been extensively surveyed, revealing that genetic changes correlated to phenotypes li... Read more »

Tags
IP-Star Compact

ERK-Induced Activation of TCF Family of SRF Cofactors Initiates a C...
Published: March, 2017

Abstract: We investigated the relationship among ERK signaling, histone modifications, and transcription factor activity, focusing on the ERK-regulated terna... Read more »

Tags
Antibody

First landscape of binding to chromosomes for a domesticated marine...
Published: March, 2017

Abstract: Setmar is a 3-exons gene coding a SET domain fused to a Hsmar1 transposase. Its different transcripts theoretically encode 8 isoforms with SET moie... Read more »

Tags
Microplex Library Preparation kit

Connexin43 controls N-cadherin transcription during collective cell...
Published: March, 2017

Abstract: Connexins are the primary components of gap junctions, providing direct links between cells in many physiological processes, including cell migrati... Read more »

Tags
Antibody

Crebbp loss cooperates with Bcl2 over-expression to promote lymphom...
Published: March, 2017

Abstract: CREBBP is targeted by inactivating mutations in follicular lymphoma (FL) and diffuse large B-cell lymphoma (DLBCL). Here, we provide evidence from ... Read more »

Tags
ChIP-seq IP-Star IP-Star Compact Microplex Library Preparation kit

Elevated Fibroblast growth factor 21 (FGF21) in obese, insulin resi...
Published: March, 2017

Abstract: Fibroblast growth factor 21 (FGF21) has emerged as an important beneficial regulator of glucose and lipid homeostasis but its levels are also abnor... Read more »

Tags
Antibody

Krüppel-like transcription factor KLF10 suppresses TGFβ-induced epi...
Published: March, 2017

Abstract: TGFβ-SMAD signaling exerts a contextual effect that suppresses malignant growth early in epithelial tumorigenesis but promotes metastasis at l... Read more »

Tags
Antibody

Assessing histone demethylase inhibitors in cells: lessons learned
Published: March, 2017

Abstract: Background Histone lysine demethylases (KDMs) are of interest as drug targets due to their regulatory roles in chromatin organization and their ... Read more »

Tags
Antibody

Conserved effect of aging on DNA methylation and association with E...
Published: February, 2017

Abstract: In humans, DNA methylation at specific CpG sites can be used to estimate the 'epigenetic clock', a biomarker of aging and health. The mechanisms th... Read more »

Tags
MethylCap

Aorta macrophage inflammatory and epigenetic changes in a murine mo...
Published: February, 2017

Abstract: Obstructive sleep apnea (OSA) affects 8-10% of the population, is characterized by chronic intermittent hypoxia (CIH), and causally associates with... Read more »

Tags
Antibody Microplex Library Preparation kit True MicroChIP kit

Type I interferon-enhanced IL-10 expression in human CD4 T cells is...
Published: February, 2017

Abstract: Type I IFN can exert pro- and anti-inflammatory activities in the immune system. Here, we have investigated the mechanism by which IFN-α enha... Read more »

Tags
IPure kit

Publications

Events