Publications,References

Net39 protects muscle nuclei from mechanical stress during thepatho...
Published: July, 2023

Abstract: Mutations in genes encoding nuclear envelope proteins lead to diseases known as nuclear envelopathies, characterized by skeletal muscle and heart a... Read more »

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Antibody

Single-cell quantification of ribosome occupancy in early mouse dev...
Published: June, 2023

Abstract: Translation regulation is critical for early mammalian embryonic development1. However, previous studies had been restricted to bulk measurements2,... Read more »

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D-Plex small RNA-seq

The NF-Y splicing signature controls hybrid EMT and ECM-related pat...
Published: June, 2023

Abstract: Aberrant splicing events are associated with colorectal cancer (CRC) and provide new opportunities for tumor diagnosis and treatment. The expressio... Read more »

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Newly added

Targeting lymphoid-derived IL-17 signaling to delay skin aging.
Published: June, 2023

Abstract: Skin aging is characterized by structural and functional changes that contribute to age-associated frailty. This probably depends on synergy betwee... Read more »

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ChIP Cross-link Gold

Polycomb protein SCML2 mediates paternal epigenetic inheritance thr...
Published: June, 2023

Abstract: Sperm chromatin retains small amounts of histones, and chromatin states of sperm mirror gene expression programs of the next generation. However, i... Read more »

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Antibody

DIS3 ribonuclease prevents the cytoplasmic accumulation of lncRNAs ...
Published: June, 2023

Abstract: Around 12% of multiple myeloma (MM) cases harbour mutations in DIS3, which encodes an RNA decay enzyme that controls the turnover of some long... Read more »

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D-Plex small RNA-seq

Nicotinamide N-methyltransferase sustains a core epigenetic program...
Published: June, 2023

Abstract: Metastatic colonization of distant organs accounts for over 90% of deaths related to solid cancers, yet the molecular determinants of metastasis re... Read more »

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Antibody

SMYD3: a new regulator of the early steps of adipocyte differentiation
Published: June, 2023

Abstract: In obesity, adipose tissue undergoes a remodeling process characterized by increased adipocyte size (hypertrophia) and number (hyperplasia). The in... Read more »

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Antibody

Single-cell m6A mapping in vivo using picoMeRIP-seq
Published: June, 2023

Abstract: Current N-methyladenosine (mA) mapping methods need large amounts of RNA or are limited to cultured cells. Through optimized sample recovery and si... Read more »

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Antibody

NUP98 and RAE1 sustain progenitor function through HDAC-dependentch...
Published: June, 2023

Abstract: Self-renewing somatic tissues rely on progenitors to support the continuous tissue regeneration. The gene regulatory network maintaining progenitor... Read more »

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Antibody

Bioengineering novel AAV9-mGULO-GT for multi-disease gene therapy:T...
Published: June, 2023

Abstract: Current clinical breakthroughs in gene therapy have brought adeno-associated virus (AAV) vectors to the forefront of gene delivery systems. Vitamin... Read more »

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Antibody

Supraphysiological Androgens Promote the Tumor Suppressive Activity...
Published: June, 2023

Abstract: The androgen receptor (AR) pathway regulates key cell survival programs in prostate epithelium. The AR represents a near-universal driver and thera... Read more »

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Microplex Library Preparation kit iDeal ChIP-seq Kit for Transcription Factors

In skeletal muscle and neural crest cells, SMCHD1 regulates biologi...
Published: June, 2023

Abstract: Many genetic syndromes are linked to mutations in genes encoding factors that guide chromatin organization. Among them, several distinct rare genet... Read more »

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Antibody iDeal ChIP-seq Kit for Transcription Factors iDeal ChIP-seq Kit for Histones Infinium Human MethylationEPIC Array Service

Direct enzymatic sequencing of 5-methylcytosine at single-baseresol...
Published: June, 2023

Abstract: 5-methylcytosine (5mC) is the most important DNA modification in mammalian genomes. The ideal method for 5mC localization would be both nondestruct... Read more »

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Premium Bisulfite Kit

Vitamin D Receptor Cross-talk with p63 Signaling PromotesEpidermal ...
Published: June, 2023

Abstract: The vitamin D receptor with its ligand 1,25 dihydroxy vitamin D (1,25D) regulates epidermal stem cell fate, such that VDR removal from Krt14 expres... Read more »

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Antibody iDeal ChIP-seq Kit for Transcription Factors

Mu opioid receptor expressing neurons in the rostral ventromedial m...
Published: June, 2023

Abstract: Repeated exposure to psychophysical stress often causes an increase in sensitivity and response to pain. This phenomenon is commonly called stress-... Read more »

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Antibody

SALL1 enforces microglia-specific DNA binding and function of SMADs...
Published: June, 2023

Abstract: Spalt-like transcription factor 1 (SALL1) is a critical regulator of organogenesis and microglia identity. Here we demonstrate that disruption of a... Read more »

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Antibody

Sexual differentiation in human malaria parasites is regulated byco...
Published: June, 2023

Abstract: For Plasmodium falciparum, the most widespread and virulent malaria parasite that infects humans, persistence depends on continuous asexual replica... Read more »

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Antibody

Identification of a deltaNp63-Dependent Basal-Like ASubtype-Specifi...
Published: June, 2023

Abstract: A major hurdle to the application of precision oncology in pancreatic cancer is the lack of molecular stratification approaches and targeted therap... Read more »

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Antibody

Hypomethylation and overexpression of Th17-associated genes is ahal...
Published: June, 2023

Abstract: BACKGROUND: The development of Crohn's disease (CD) involves immune cell signaling pathways regulated by epigenetic modifications. Aberrant DNA met... Read more »

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Antibody Microplex Library Preparation kit

Mutant FUS induces chromatin reorganization in the hippocampus anda...
Published: June, 2023

Abstract: Cytoplasmic mislocalization of the nuclear Fused in Sarcoma (FUS) protein is associated to amyotrophic lateral sclerosis (ALS) and frontotemporal d... Read more »

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Antibody Microplex Library Preparation kit ChIP Cross-link Gold

Effect of Aerobic/Strength Training on RANKL Gene DNA Methylation L...
Published: June, 2023

Abstract: BACKGROUND: The osteoclastogenesis RANKL gene plays a key role in bone remodeling. The hypomethylation of its promoter region may cause osteoporosi... Read more »

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Newly added

Dynamic PRC1-CBX8 stabilizes a porous structure of chromatin conden...
Published: May, 2023

Abstract: The compaction of chromatin is a prevalent paradigm in gene repression. Chromatin compaction is commonly thought to repress transcription by restri... Read more »

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ATAC-seq

Pathologic HDAC1/c-Myc signaling axis is responsible forangiotensin...
Published: May, 2023

Abstract: High-fat diet (HFD)-induced obesity is a cause of resistant hypertension. We have shown a possible link between histone deacetylases (HDACs) and re... Read more »

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Antibody

Pyruvate Kinase M (PKM) binds ribosomes in a poly-ADPribosylation d...
Published: May, 2023

Abstract: In light of the numerous studies identifying post-transcriptional regulators on the surface of the endoplasmic reticulum (ER), we asked whether the... Read more »

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D-Plex RNA-seq kit D-Plex small RNA-seq

The circadian clock CRY1 regulates pluripotent stem cell identity a...
Published: May, 2023

Abstract: Distinct metabolic conditions rewire circadian-clock-controlled signaling pathways leading to the de novo construction of signal transduction netwo... Read more »

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Antibody

Neonatal immune challenge poses a sex-specific risk for epigeneticm...
Published: May, 2023

Abstract: While the precise processes underlying a sex bias in the development of central nervous system (CNS) disorders are unknown, there is growing eviden... Read more »

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iDeal ChIP-seq Kit for Histones

Curcumin activates a ROS/KEAP1/NRF2/miR-34a/b/c cascade tosuppress ...
Published: May, 2023

Abstract: Curcumin, a natural phytochemical isolated from tumeric roots, represents a candidate for prevention and therapy of colorectal cancer/CRC. However,... Read more »

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iDeal ChIP-qPCR

Knockout of TRDMT1 methyltransferase affects DNA methylome ingliobl...
Published: May, 2023

Abstract: Purpose: We have previously shown that TRDMT1 methyltransferase is a regulator of chemotherapy-associated responses in glioblastoma cells. Des... Read more »

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Premium RRBS Kit

UMSBP2 is chromatin remodeler that functions in regulation of genee...
Published: May, 2023

Abstract: Universal Minicircle Sequence binding proteins (UMSBPs) are CCHC-type zinc-finger proteins that bind the single-stranded G-rich UMS sequence, conse... Read more »

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ATAC-seq

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