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Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Epigenetic Analysis of ST3GAL3 and other Sialic Acid Metabolism Gen...
Published: October, 2024
Abstract: Research indicates that the underlying neurobiology of Attention Deficit/Hyperactivity Disorder (ADHD) may stem from a combination of genetic and e... Read more »
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Infinium Human MethylationEPIC Array Service
DNA demethylation triggers cell free DNA release in colorectal canc...
Published: October, 2024
Abstract: Background Liquid biopsy based on cell-free DNA (cfDNA) analysis holds significant promise as a minimally invasive approach for the diagnosis, gen... Read more »
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ATAC-seq
Multi-omics characterization of chronic social defeat stress recall...
Published: October, 2024
Abstract: Susceptibility to chronic social stressors often results in the development of mental health disorders including major depressive and anxiety disor... Read more »
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Premium RRBS Kit
Prediction of brain metastasis development with DNA methylation sig...
Published: October, 2024
Abstract: Brain metastases (BMs) are the most common and among the deadliest brain tumors. Currently, there are no reliable predictors of BM development from... Read more »
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MagMeDIP kit IPure kit
The small inhibitor WM-1119 effectively targets KAT6A-rearranged AM...
Published: October, 2024
Abstract: Background The epigenetic factors KAT6A (MOZ/MYST3) and KMT2A (MLL/MLL1) interact in normal hematopoiesis to regulate progenitors’ self-rene... Read more »
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Antibody Microplex Library Preparation kit
Integrated multi-omics analysis of PBX1 in mouse adult neural stem-...
Published: October, 2024
Abstract: Developmental transcription factors act in networks, but how these networks achieve cell- and tissue specificity is still poorly understood. Here, ... Read more »
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Antibody Microplex Library Preparation kit
HNF1β bookmarking involves Topoisomerase 1 activation and DNA topol...
Published: October, 2024
Abstract: Highlights HNF1β mitotic site binding is preserved with a specific methanol/formaldehyde ChIP BTBD2, an HNF1β partner... Read more »
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IPure kit Microplex Library Preparation kit Tagmentase
Pesticide-induced transgenerational alterations of genome-wide DNA ...
Published: October, 2024
Abstract: The unsustainable use of manmade chemicals poses significant threats to biodiversity and human health. Emerging evidence highlights the potential o... Read more »
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Premium RRBS Kit
5-Hydroxymethylcytosine in circulating cell-free DNA as a potential...
Published: October, 2024
Abstract: Background SLE is a complex autoimmune disease with heterogeneous manifestations and unpredictable outcomes. Early diagnosis is challenging ... Read more »
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Antibody
RNA m5C oxidation by TET2 regulates chromatin state and leukaemogen...
Published: October, 2024
Abstract: Mutation of tet methylcytosine dioxygenase 2 (encoded by TET2) drives myeloid malignancy initiation and progression1,2,3. TET2 deficiency is k... Read more »
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Antibody
Epigenome profiling identifies H3K27me3 regulation of extra-cellula...
Published: October, 2024
Abstract: Epigenetic mechanisms regulate gene expression programs during neurogenesis, but the extent of epigenetic remodelling during human cortical develop... Read more »
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CUT&Tag
RNA polymerase II transcription initiation in holo-TFIID-depleted m...
Published: September, 2024
Abstract: The recognition of core promoter sequences by TFIID is the first step in RNA polymerase II (Pol II) transcription initiation. Metazoan holo-TFIID i... Read more »
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Microplex Library Preparation kit
Trained immunity is regulated by T cell-induced CD40-TRAF6 signaling
Published: September, 2024
Abstract: Trained immunity is characterized by histone modifications and metabolic changes in innate immune cells following exposure to inflammatory signals,... Read more »
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Antibody
Legionella pneumophila modulates macrophage functions through epige...
Published: September, 2024
Abstract: Legionella pneumophila is a pathogen which can lead to a severe form of pneumonia in humans known as Legionnaires disease after replication in... Read more »
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Antibody
Two-factor authentication underpins the precision of the piRNA pathway
Published: September, 2024
Abstract: The PIWI-interacting RNA (piRNA) pathway guides the DNA methylation of young, active transposons during germline development in male mice. piRNAs t... Read more »
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CUT&Tag
Multiplex, single-cell CRISPRa screening for cell type specific reg...
Published: September, 2024
Abstract: CRISPR-based gene activation (CRISPRa) is a strategy for upregulating gene expression by targeting promoters or enhancers in a tissue/cell-type spe... Read more »
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Tagmentase
Single-cell multi-omics, spatial transcriptomics and systematic per...
Published: September, 2024
Abstract: Cranial neural crest (NC) cells, which can migrate, adopt multiple fates, and form most of the craniofacial skeleton, are an excellent model for st... Read more »
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Antibody True MicroChIP kit
Optimization of ribosome profiling in plants including structural a...
Published: September, 2024
Abstract: Background Ribosome profiling (or Ribo-seq) is a technique that provides genome-wide information on the translational landscape (translatome). Acr... Read more »
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D-Plex small RNA-seq
Systematic prioritization of functional variants and effector genes...
Published: September, 2024
Abstract: Genome-wide association studies of colorectal cancer (CRC) have identified 170 autosomal risk loci. However, for most of these, the functional vari... Read more »
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Antibody
An ERRα-ZEB1 transcriptional signature predicts survival in triple-...
Published: September, 2024
Abstract: Background. Transcription factors (TFs) act together with co-regulators to modulate the expression of their target genes, which eventually dictate... Read more »
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iDeal ChIP-seq Kit for Transcription Factors
Auto-expansion of in vivo HDAd-transduced hematopoietic stem cells ...
Published: September, 2024
Abstract: We developed an in vivo hematopoietic stem cell (HSC) gene therapy approach that does not require cell transplantation. To achieve t... Read more »
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Tagmentase
Nuclear lamin A/C phosphorylation by loss of androgen receptor lead...
Published: September, 2024
Abstract: Alterations in nuclear structure and function are hallmarks of cancer cells. Little is known about these changes in Cancer-Associated Fibroblasts (... Read more »
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iDeal ChIP-seq Kit for Transcription Factors Tagmentase
A critical role for HNF4α in polymicrobial sepsis-associated metabo...
Published: September, 2024
Abstract: In sepsis, limited food intake and increased energy expenditure induce a starvation response, which is compromised by a quick decline in the expres... Read more »
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Tagmentase
Bivalent chromatin accommodates survivin and BRG1/SWI complex to ac...
Published: September, 2024
Abstract: Background Bivalent regions of chromatin (BvCR) are characterized by trimethylated lysine 4 (H3K4me3) and lysine 27 on histone H3 (H3K27me3)... Read more »
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Antibody
Single cell genome and epigenome co-profiling reveals hardwiring an...
Published: September, 2024
Abstract: Understanding the impact of genetic alterations on epigenomic phenotypes during breast cancer progression is challenging with unimodal measurements... Read more »
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Tagmentase
Precision and efficacy of RNA-guided DNA integration in high-expres...
Published: September, 2024
Abstract: Gene replacement therapies primarily rely on adeno-associated virus (AAV) vectors for transgene expression. However, episomal expression can declin... Read more »
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Tagmentase
Triphenyl Phosphate Alters Methyltransferase Expression and Induces...
Published: August, 2024
Abstract: Emerging environmental contaminants, organophosphate flame retardants (OPFRs), pose significant threats to ecosystems and human health. Despite num... Read more »
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Premium RRBS Kit
An atlas of the human liver diurnal transcriptome and its perturbat...
Published: August, 2024
Abstract: Chronic liver disease and cancer are global health challenges. The role of the circadian clock as a regulator of liver physiology and disease is we... Read more »
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Microplex Library Preparation kit
Peripheral nervous system mediates body-wide stem cell activation f...
Published: August, 2024
Abstract: Many species throughout the animal kingdom naturally regenerate complex body parts following amputation. Most research in appendage regeneration ha... Read more »
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Tagmentase
RNA sequestration in P-bodies sustains myeloid leukaemia
Published: August, 2024
Abstract: Post-transcriptional mechanisms are fundamental safeguards of progenitor cell identity and are often dysregulated in cancer. Here, we identified re... Read more »
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Antibody CUT&Tag

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