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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

BMP restricts stemness of intestinal Lgr5(+) stem cells by directly...
Published: January, 2017
Abstract: The intestinal epithelium possesses a remarkable self-renewal ability, which is mediated by actively proliferating Lgr5+ stem cells. Bone morphogen... Read more »
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Microplex Library Preparation kit
Differentiation of Mouse Enteric Nervous System Progenitor Cells is...
Published: January, 2017
Abstract: Background & Aims Maintenance and differentiation of progenitor cells in the developing enteric nervous system (ENS) are controlled by molec... Read more »
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Bioruptor Antibody True MicroChIP kit
Rapid Recall Ability of Memory T cells is Encoded in their Epigenome
Published: January, 2017
Abstract: Even though T-cell receptor (TCR) stimulation together with co-stimulation is sufficient for the activation of both naïve and memory T cells, ... Read more »
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Antibody IP-Star Compact
Distinct 5-methylcytosine profiles in poly(A) RNA from mouse embryo...
Published: January, 2017
Abstract: Background Recent work has identified and mapped a range of posttranscriptional modifications in mRNA, including methylation of the N6 and N1 po... Read more »
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Antibody
HMCan-diff: a method to detect changes in histone modifications in ...
Published: January, 2017
Abstract: Comparing histone modification profiles between cancer and normal states, or across different tumor samples, can provide insights into understandin... Read more »
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Antibody
High resolution methylation analysis of the HoxA5 regulatory region...
Published: January, 2017
Abstract: Homeobox genes encode a group of DNA binding regulatory proteins whose key function occurs in the spatial-temporal organization of genome during em... Read more »
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Antibody Histone ChIP kit
Determinants of orofacial clefting II: Effects of 5-Aza-2′-deoxycyt...
Published: January, 2017
Abstract: Defects in development of the secondary palate, which arise from the embryonic first branchial arch (1-BA), can cause cleft palate (CP). Administra... Read more »
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MethylCap
m6A-dependent maternal mRNA clearance facilitates zebrafish materna...
Published: December, 2016
Abstract: The maternal-to-zygotic transition (MZT) is one of the most profound and tightly orchestrated processes during the early life of embryos, yet facto... Read more »
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Bioruptor
The Role of Angiotensin Converting Enzyme 1 within the median preop...
Published: December, 2016
Abstract: Sustained hypertension is an important consequence of obstructive sleep apnea. An animal model of the hypoxemia associated with sleep apnea, chroni... Read more »
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LowCell ChIP kit
Arabidopsis SWI/SNF chromatin remodeling complex binds both promote...
Published: December, 2016
Abstract: ATP-dependent chromatin remodeling complexes are important regulators of gene expression in Eukaryotes. In plants, SWI/SNF-type complexes have been... Read more »
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Bioruptor Antibody
Integrative "-Omics" Analysis in Primary Human Hepatocytes Unravels...
Published: December, 2016
Abstract: Cyclosporine A (CsA) is an undecapeptide with strong immunosuppressant activities and is used a lot after organ transplantation. Furthermore, it ma... Read more »
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MagMeDIP kit
Stem cell-like transcriptional reprogramming mediates metastatic
Published: December, 2016
Abstract: Inhibitors of the mechanistic target of rapamycin (mTOR) are currently used to treat advanced metastatic breast cancer. However, whether an aggress... Read more »
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Bioruptor HighCell ChIP kit
Evaluating the Feasibility of DNA Methylation Analyses Using Long-T...
Published: December, 2016
Abstract: We here characterize the usability of archival formalin-fixed paraffin-embedded (FFPE) brain tissue as a resource for genetic and DNA methylation a... Read more »
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Bioruptor MagMeDIP kit IP-Star Compact
Co-occurrence of Histone H3 K27M and BRAF V600E mutations in paedia...
Published: December, 2016
Abstract: Ganglioglioma (GG) is a grade I tumour characterized by alterations in the MAPK pathway, including BRAF V600E mutation. Recently, diffuse midline g... Read more »
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Antibody
Epigenetic stress responses induce muscle stem-cell ageing by Hoxa9...
Published: December, 2016
Abstract: The functionality of stem cells declines during ageing, and this decline contributes to ageing-associated impairments in tissue regeneration and fu... Read more »
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Antibody
Nitric oxide modulates histone acetylation at stress genes by inhib...
Published: December, 2016
Abstract: Histone acetylation, which is an important mechanism to regulate gene expression, is controlled by the opposing action of histone acetyltransferase... Read more »
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Bioruptor Antibody IPure kit Microplex Library Preparation kit
Alu repeats as transcriptional regulatory platforms in macrophage r...
Published: December, 2016
Abstract: To understand the epigenetic regulation of transcriptional response of macrophages during early-stage M. tuberculosis (Mtb) infection, we performed... Read more »
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Bioruptor
Voluntary Physical Exercise Induces Expression and Epigenetic Remod...
Published: December, 2016
Abstract: A healthy lifestyle, including regular physical exercise, is generally believed to improve cognitive function and enhance neurogenesis. Such physic... Read more »
Epigenetic Networks Regulate the Transcriptional Program in Memory ...
Published: December, 2016
Abstract: Epigenetic mechanisms play a critical role during differentiation of T cells by contributing to the formation of stable and heritable transcription... Read more »
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ChIP-seq
Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic ...
Published: December, 2016
Abstract: Induction of trained immunity (innate immune memory) is mediated by activation of immune and metabolic pathways that result in epigenetic rewiring ... Read more »
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Antibody
FOXA1 Directs H3K4 Monomethylation at Enhancers via Recruitment of ...
Published: December, 2016
Abstract: FOXA1 is a pioneer factor that binds to enhancer regions that are enriched in H3K4 mono- and dimethylation (H3K4me1 and H3K4me2). We performed a FO... Read more »
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Antibody
Immunometabolic Pathways in BCG-Induced Trained Immunity
Published: December, 2016
Abstract: The protective effects of the tuberculosis vaccine Bacillus Calmette-Guerin (BCG) on unrelated infections are thought to be mediated by long-term m... Read more »
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Antibody
A transcription factor pulse can prime chromatin for heritable tran...
Published: December, 2016
Abstract: Short-term and long-term transcriptional memory is the phenomenon whereby the kinetics or magnitude of gene induction is enhanced following a prior... Read more »
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Antibody
Distinct and Shared Determinants of Cardiomyocyte Contractility in ...
Published: December, 2016
Abstract: The realization of personalized medicine through human induced pluripotent stem cell (iPSC) technology can be advanced by transcriptomics, epigenom... Read more »
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Bioruptor IP-Star Compact
Potent and selective bivalent inhibitors of BET bromodomains
Published: December, 2016
Abstract: Proteins of the bromodomain and extraterminal (BET) family, in particular bromodomain-containing protein 4 (BRD4), are of great interest as biologi... Read more »
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Antibody
Lhx2 interacts with the NuRD complex and regulates cortical neuron ...
Published: December, 2016
Abstract: n the developing cerebral cortex, sequential transcriptional programs take neuroepithelial cells from proliferating progenitors to differentiated n... Read more »
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Antibody
Genomic Characterization of Metformin Hepatic Response
Published: November, 2016
Abstract: Metformin is used as a first-line therapy for type 2 diabetes (T2D) and prescribed for numerous other diseases. However, its mechanism of action in... Read more »
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LowCell ChIP kit IPure kit
ING1 regulates rRNA levels by altering nucleolar chromatin structur...
Published: November, 2016
Abstract: Epigenetic, transcriptional and signaling processes in the nucleolus regulate rRNA transcription and cell growth. We report here that the tumor sup... Read more »
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Antibody
Jarid2 binds mono-ubiquitylated H2A lysine 119 to mediate crosstalk...
Published: November, 2016
Abstract: The Polycomb repressive complexes PRC1 and PRC2 play a central role in developmental gene regulation in multicellular organisms. PRC1 and PRC2 modi... Read more »
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Antibody
Gene regulatory networks in neural cell fate acquisition from genom...
Published: November, 2016
Abstract: Neural cell fate acquisition is mediated by transcription factors expressed in nascent neuroectoderm, including Geminin and members of the Zic tran... Read more »
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Antibody

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  • FASEB Biological Methylation: Fundamental Mechanisms
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    Jul 28-Aug 1, 2024
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