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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

miR-125b-1 is repressed by histone modifications in breast cancer c...
Published: July, 2016
Abstract: PURPOSE: Downregulation of miR-125b-1 is associated with poor prognosis in breast cancer patients. In this work we investigated the effect of hi... Read more »
Premalignant SOX2 overexpression in the fallopian tubes of ovarian ...
Published: July, 2016
Abstract: Current screening methods for ovarian cancer can only detect advanced disease. Earlier detection has proved difficult because the molecular precurs... Read more »
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Antibody
The dynamic interactome and genomic targets of Polycomb complexes d...
Published: July, 2016
Abstract: Although the core subunits of Polycomb group (PcG) complexes are well characterized, little is known about the dynamics of these protein complexes ... Read more »
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Bioruptor Antibody
Epigenetic Modifications with DZNep, NaBu and SAHA in Luminal and M...
Published: July, 2016
Abstract: BACKGROUND/AIM: Numerous studies have shown that breast cancer and epigenetic mechanisms have a very powerful interactive relation. The MCF7 cell ... Read more »
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IP-Star Antibody
Differential Incorporation of β-actin as A Component of RNA Polymer...
Published: July, 2016
Abstract: Objective Nuclear actin is involved in transcription regulation by recruitment of histone modifiers and chromatin remodelers to the regulatory... Read more »
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Histone ChIP kit
Genome-Wide DNA Methylation in Mixed Ancestry Individuals with Diab...
Published: June, 2016
Abstract: Aims. To conduct a genome-wide DNA methylation in individuals with type 2 diabetes, individuals with prediabetes, and control mixed ancestry indivi... Read more »
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Antibody
Chromatin accessibility maps of chronic lymphocytic leukaemia ident...
Published: June, 2016
Abstract: Chronic lymphocytic leukaemia (CLL) is characterized by substantial clinical heterogeneity, despite relatively few genetic alterations. To provide ... Read more »
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Antibody
Expression of the Parkinson's Disease-Associated Gene Alpha-Synucle...
Published: June, 2016
Abstract: Alpha-synuclein is an abundant neuronal protein which has been associated with physiological processes like synaptic function, neurogenesis, and ne... Read more »
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Antibody
Deletion of Polycomb Repressive Complex 2 From Mouse Intestine Caus...
Published: June, 2016
Abstract: BACKGROUND & AIMS: The polycomb repressive complex 2 (PRC2) regulates differentiation by contributing to repression of gene expression and the... Read more »
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Microplex Library Preparation kit
Molecular and Epigenetic Biomarkers in Luminal Androgen Receptor: A...
Published: June, 2016
Abstract: Read more »
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IP-Star Antibody
Efficiency of methylated DNA immunoprecipitation bisulphite sequenc...
Published: June, 2016
Abstract: We compared four common methods for measuring DNA methylation levels and recommended the most efficient method in terms of cost and coverage. MATE... Read more »
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MagMeDIP kit
Dnmt2/Trdmt1 as Mediator of RNA Polymerase II Transcriptional Activ...
Published: June, 2016
Abstract: Dnmt2/Trdmt1 is a methyltransferase, which has been shown to methylate tRNAs. Deficient mutants were reported to exhibit various, seemingly unrelat... Read more »
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Antibody 5mC (C15200081)
Rebalancing gene haploinsufficiency in vivo by targeting chromatin
Published: June, 2016
Abstract: Congenital heart disease (CHD) affects eight out of 1,000 live births and is a major social and health-care burden. A common genetic cause of CHD i... Read more »
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True MicroChIP kit
Heat shock represses rRNA synthesis by inactivation of TIF-IA and l...
Published: June, 2016
Abstract: Attenuation of ribosome biogenesis in suboptimal growth environments is crucial for cellular homeostasis and genetic integrity. Here, we show that ... Read more »
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Antibody
Aberrant DNA methylation of WNT pathway genes in the development an...
Published: May, 2016
Abstract: The WNT signaling pathway has an essential role in colorectal carcinogenesis and progression, which involves a cascade of genetic and epigenetic ch... Read more »
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IP-Star Compact
Epigenetic inactivation of the CpG demethylase TET1 as a DNA methyl...
Published: May, 2016
Abstract: Promoter CpG methylation is a fundamental regulatory process of gene expression. TET proteins are active CpG demethylases converting 5-methylcytosi... Read more »
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Antibody 5mC (C15200081)
PHF13 is a molecular reader and transcriptional co-regulator of H3K...
Published: May, 2016
Abstract: PHF13 is a chromatin affiliated protein with a functional role in differentiation, cell division, DNA damage response and higher chromatin order. T... Read more »
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Antibody
Impairment of DNA Methylation Maintenance Is the Main Cause of Glob...
Published: May, 2016
Abstract: Global demethylation is part of a conserved program of epigenetic reprogramming to naive pluripotency. The transition from primed hypermethylated e... Read more »
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Microplex Library Preparation kit
Molecular mechanisms in H2O2-induced increase in AT1 receptor gene ...
Published: May, 2016
Abstract: The AT1 receptor (AT1R) mediates the manifold actions of Angiotensin II in the cardiovascular system. This study probed the molecular mechanisms th... Read more »
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LowCell ChIP kit
Functional incompatibility between the generic NF-κB motif and a su...
Published: May, 2016
Abstract: Of the various genetic subtypes of HIV-1, HIV-2 and SIV, only in subtype C of HIV-1, a genetically variant NF-κB binding site is found at the... Read more »
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Antibody
mTOR transcriptionally and post-transcriptionally regulates Npm1 ge...
Published: May, 2016
Abstract: The mammalian target of rapamycin (mTOR) plays essential roles in the regulation of growth-related processes such as protein synthesis, cell sizing... Read more »
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Antibody
Genic DNA methylation drives codon bias in stony corals
Published: May, 2016
Abstract: Gene body methylation (gbM) is an ancestral and widespread feature in Eukarya, yet its adaptive value and evolutionary implications remain unresolv... Read more »
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MethylCap
Persistent Alterations in Microglial Enhancers in a Model of Chroni...
Published: May, 2016
Abstract: Chronic pain is a common and devastating condition that induces well-characterized changes in neurons and microglia. One major unanswered question ... Read more »
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True MicroChIP kit
Epigenetic alterations of CYP19A1 gene in Cumulus cells and its rel...
Published: May, 2016
Abstract: PURPOSE: The purpose of the present study was to investigate the epigenetic mechanisms responsible for the aberrant aromatase expression (CYP19A... Read more »
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LowCell ChIP kit
RESEARCH RESOURCE: Changes in gene expression and Estrogen Receptor...
Published: May, 2016
Abstract: Transcriptional regulation by the Estrogen Receptor α (ER) has been investigated mainly in breast cancer cell lines but estrogens such as 17&... Read more »
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Antibody
MicroRNAs of the miR-290-295 Family Maintain Bivalency in Mouse Emb...
Published: May, 2016
Abstract: Numerous developmentally regulated genes in mouse embryonic stem cells (ESCs) are marked by both active (H3K4me3)- and polycomb group (PcG)-mediate... Read more »
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Antibody
PKC-mediated phosphorylation of BCL11B at Serine 2 negatively regul...
Published: May, 2016
Abstract: The transcription factor BCL11B/CTIP2 is a major regulatory protein implicated in various aspects of development, function and survival of T cells.... Read more »
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Antibody
Osterix and RUNX2 are Transcriptional Regulators of Sclerostin in H...
Published: May, 2016
Abstract: Sclerostin, encoded by the SOST gene, works as an inhibitor of the Wnt pathway and therefore is an important regulator of bone homeostasis. Due to ... Read more »
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Bioruptor ChIP-seq LowCell ChIP kit Article alert
EZH2 is overexpressed in adrenocortical carcinoma and is associated...
Published: May, 2016
Abstract: Adrenal Cortex Carcinoma (ACC) is an aggressive tumour with poor prognosis. Common alterations in patients include constitutive WNT/β-catenin ... Read more »
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Antibody
Aflatoxin B1 induces persistent epigenomic effects in primary human...
Published: May, 2016
Abstract: Chronic exposure to aflatoxin B1 (AFB1) has, in certain regions in the world, been strongly associated with hepatocellular carcinoma (HCC) developm... Read more »
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MagMeDIP kit Article alert

イベント

  • FASEB Biological Methylation: Fundamental Mechanisms
    Porto, Portugal
    Jul 28-Aug 1, 2024
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