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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Fumarate is an epigenetic modifier that elicits epithelial-to-mesen...
Published: August, 2016
Abstract: Mutations of the tricarboxylic acid cycle enzyme fumarate hydratase cause hereditary leiomyomatosis and renal cell cancer1. Fumarate hydratase-defi... Read more »
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Antibody
Chromatin remodeling regulates catalase expression during cancer ce...
Published: August, 2016
Abstract: Regulation of ROS metabolism plays a major role in cellular adaptation to oxidative stress in cancer cells, but the molecular mechanism that regula... Read more »
PionX sites mark the X chromosome for dosage compensation
Published: August, 2016
Abstract: The rules defining which small fraction of related DNA sequences can be selectively bound by a transcription factor are poorly understood. One of t... Read more »
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Microplex Library Preparation kit
Noncoding somatic and inherited single-nucleotide variants converge...
Published: August, 2016
Abstract: Sustained expression of the estrogen receptor-α (ESR1) drives two-thirds of breast cancer and defines the ESR1-positive subtype. ESR1 engages... Read more »
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Antibody
Remodelling of the hepatic epigenetic landscape of glucose-intolera...
Published: August, 2016
Abstract: The rainbow trout, a carnivorous fish, displays a ‘glucose-intolerant’ phenotype revealed by persistent hyperglycaemia when fed a high ... Read more »
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Antibody
Dynamic Interplay between the Transcriptome and Methylome in Respon...
Published: August, 2016
Abstract: In recent years, it has been shown that free radicals not only react directly with DNA but also regulate epigenetic processes such as DNA methylati... Read more »
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MagMeDIP kit IPure kit
H3.3 demarcates GC-rich coding and subtelomeric regions and serves ...
Published: August, 2016
Abstract: Histones, by packaging and organizing the DNA into chromatin, serve as essential building blocks for eukaryotic life. The basic structure of the ch... Read more »
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Antibody
Clinical, Imaging, Histopathological and Molecular Characterization...
Published: August, 2016
Abstract: Anaplastic ganglioglioma (AGG) is a rare and malignant variant of ganglioglioma. According to the World Health Organization classification version ... Read more »
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Antibody
The Development of a Viral Mediated CRISPR/Cas9 System with Doxycyc...
Published: August, 2016
Abstract: The RNA-guided Cas9 nuclease, from the type II prokaryotic Clustered Regularly Interspersed Short Palindromic Repeats (CRISPR) adaptive immune syst... Read more »
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Antibody
reChIP-seq reveals widespread bivalency of H3K4me3 and H3K27me3 in ...
Published: August, 2016
Abstract: The combinatorial action of co-localizing chromatin modifications and regulators determines chromatin structure and function. However, identifying ... Read more »
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Antibody Bioruptor Plus Microplex Library Preparation kit
HDAC1 negatively regulates Bdnf and Pvalb required for parvalbumin ...
Published: August, 2016
Abstract: During early postnatal development, neuronal circuits are sculpted by sensory experience provided by the external environment. This experience-depe... Read more »
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Antibody
Anti-RAINBOW dye-specific antibodies as universal tools for the vis...
Published: August, 2016
Abstract: Western blotting is one of the most widely used techniques in molecular biology and biochemistry. Prestained proteins are used as molecular weight ... Read more »
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Antibody
Polycomb repressive complex 2 (PRC2) silences genes responsible for...
Published: August, 2016
Abstract: Normal brain function depends on the interaction between highly specialized neurons that operate within anatomically and functionally distinct brai... Read more »
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LowCell ChIP kit
Phenotypic Plasticity through Transcriptional Regulation of the Evo...
Published: August, 2016
Abstract: Phenotypic plasticity is the ability of a given genotype to produce different phenotypes in response to distinct environmental conditions. Phenotyp... Read more »
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Antibody IPure kit
Ordered chromatin changes and human X chromosome reactivation by ce...
Published: August, 2016
Abstract: Erasure of epigenetic memory is required to convert somatic cells towards pluripotency. Reactivation of the inactive X chromosome (Xi) has been use... Read more »
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Antibody
MEF2C protects bone marrow B-lymphoid progenitors during stress hae...
Published: August, 2016
Abstract: DNA double strand break (DSB) repair is critical for generation of B-cell receptors, which are pre-requisite for B-cell progenitor survival. Howeve... Read more »
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Antibody
Toxoplasma gondii TgIST co-opts host chromatin repressors dampening...
Published: August, 2016
Abstract: An early hallmark of Toxoplasma gondii infection is the rapid control of the parasite population by a potent multifaceted innate immune response th... Read more »
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Antibody
Activating Receptor Signals Drive Receptor Diversity in Developing ...
Published: August, 2016
Abstract: It has recently been appreciated that NK cells exhibit many features reminiscent of adaptive immune cells. Considerable heterogeneity exists with r... Read more »
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True MicroChIP kit
Loss of cohesin complex components STAG2 or STAG3 confers resistanc...
Published: August, 2016
Abstract: The protein kinase B-Raf proto-oncogene, serine/threonine kinase (BRAF) is an oncogenic driver and therapeutic target in melanoma. Inhibitors of BR... Read more »
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Antibody
Hormetic Shifting of Redox Environment by Pro-Oxidative Resveratrol...
Published: August, 2016
Abstract: Resveratrol has gained tremendous interest owing to multiple reported health-beneficial effects. However, the underlying key mechanism of action of... Read more »
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Antibody
Enhancer decommissioning by Snail1-induced competitive displacement...
Published: August, 2016
Abstract: Transcriptional silencing is a major cause for the inactivation of tumor suppressor genes, however, the underlying mechanisms are only poorly under... Read more »
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Antibody
Comparative DNA Methylation and Gene Expression Analysis Identifies...
Published: August, 2016
Abstract: Aims For the majority of congenital heart diseases (CHDs), the full complexity of the causative molecular network, which is driven by genetic, ep... Read more »
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MethylCap
Normal stroma suppresses cancer cell proliferation via mechanosensi...
Published: August, 2016
Abstract: Tissue homeostasis is dependent on the controlled localization of specific cell types and the correct composition of the extracellular stroma. Whil... Read more »
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Antibody
Severe muscle wasting and denervation in mice lacking the RNA-bindi...
Published: August, 2016
Abstract: Innervation of skeletal muscle by motor neurons occurs through the neuromuscular junction, a cholinergic synapse essential for normal muscle growth... Read more »
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Antibody
Molecular and epigenetic features of melanomas and tumor immune m...
Published: August, 2016
Abstract: Background Ipilimumab (Ipi) improves the survival of advanced melanoma patients with an incremental long-term benefit in 10–15 % of p... Read more »
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MethylCap
Role of CREB on heme oxygenase-1 induction in adrenal cells: involv...
Published: August, 2016
Abstract: In addition to the well-known function of ACTH as the main regulator of adrenal steroidogenesis, we have previously demonstrated its effect on the ... Read more »
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Antibody
RNA polymerase II promoter-proximal pausing in mammalian long non-c...
Published: August, 2016
Abstract: Mammalian genomes encode a large number of non-coding RNAs (ncRNAs) that greatly exceed mRNA genes. While the physiological and pathological roles ... Read more »
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IP-Star Compact
Epigenetic dynamics of monocyte-to-macrophage differentiation
Published: July, 2016
Abstract: BACKGROUND: Monocyte-to-macrophage differentiation involves major biochemical and structural changes. In order to elucidate the role of gene reg... Read more »
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Antibody IP-Star Compact
Integrative epigenomic analysis reveals unique epigenetic signature...
Published: July, 2016
Abstract: Background Germline stem cells play an essential role in establishing the fertility of an organism. Although extensively characterized, the regu... Read more »
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MethylCap
Converging disease genes in ICF syndrome: ZBTB24 controls expressio...
Published: July, 2016
Abstract: For genetically heterogeneous diseases a better understanding of how the underlying gene defects are functionally interconnected will be important ... Read more »
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Bioruptor Antibody

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