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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Deep sequencing reveals new aspects of progesterone receptor signal...
Published: June, 2014
Abstract: Despite the pleiotropic effects of the progesterone receptor in breast cancer, the molecular mechanisms in play remain largely unknown. To gain a g... Read more »
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DNA shearing Bioruptor
Frizzled 7 Expression Is Positively Regulated by SIRT1 and β-Cateni...
Published: June, 2014
Abstract: The Wnt signaling pathway is often chronically activated in diverse human tumors, and the Frizzled (FZD) family of receptors for Wnt ligands, are c... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Insulin regulates carboxypeptidase E by modulating translation init...
Published: June, 2014
Abstract: Insulin resistance, hyperinsulinemia, and hyperproinsulinemia occur early in the pathogenesis of type 2 diabetes (T2D). Elevated levels of proinsul... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Functional Analysis of the TRIB1 Associated Locus Linked to Plasma ...
Published: June, 2014
Abstract: BACKGROUND: The TRIB1 locus has been linked to hepatic triglyceride metabolism in mice and to plasma triglycerides and coronary artery disease in h... Read more »
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Bioruptor Chromatin Shearing
Impact of MLL5 expression on decitabine efficacy and DNA methylatio...
Published: June, 2014
Abstract: Hypomethylating agents are widely used in patients with myelodysplastic syndromes and unfit patients with acute myeloid leukemia. However, it is no... Read more »
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MagMeDIP kit
Chronic alcohol consumption leads to neurochemical changes in the n...
Published: June, 2014
Abstract: Neuropeptide Y (NPY)- and acetylcholine-containing interneurons of the nucleus accumbens (NAc) seem to play a major role in the rewarding effects o... Read more »
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Bioruptor Tissue Homogenization
Differential regulation of Gli proteins by Sufu in the lung affects...
Published: June, 2014
Abstract: Mammalian Hedgehog (Hh) signaling relies on three Gli transcription factors to mediate Hh responses. This process is controlled in part by a major ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
A specific polymorphism in Mycobacterium tuberculosis H37Rv causes ...
Published: June, 2014
Abstract: The ESX-1 secreted virulence factor ESAT-6 is one of the major and most well-studied virulence factors of Mycobacterium tuberculosis given that its... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Seminoma and embryonal carcinoma footprints identified by analysis ...
Published: June, 2014
Abstract: BACKGROUND: Originating from Primordial Germ Cells/gonocytes and developing via a precursor lesion called Carcinoma In Situ (CIS), Germ Cell Cancer... Read more »
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Antibody LowCell ChIP kit H3K4me3 (C15410003) IPure kit
Ezh2 regulates transcriptional and posttranslational expression of ...
Published: June, 2014
Abstract: Acquired aplastic anemia (AA) is a potentially fatal bone marrow (BM) failure syndrome. IFN-γ-producing Th1 CD4(+) T cells mediate the immune destr... Read more »
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Antibody H3K27me3 (C15410069)
Genome-wide characterization reveals complex interplay between TP53...
Published: June, 2014
Abstract: In response to genotoxic stress the TP53 tumour suppressor activates target gene expression to induce cell cycle arrest or apoptosis depending on t... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
The noncoding RNA IPW regulates the imprinted DLK1-DIO3 locus in an...
Published: June, 2014
Abstract: Parental imprinting is a form of epigenetic regulation that results in parent-of-origin differential gene expression. To study Prader-Willi syndrom... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
DNMT3L promotes quiescence in postnatal spermatogonial progenitor c...
Published: June, 2014
Abstract: The ability of adult stem cells to reside in a quiescent state is crucial for preventing premature exhaustion of the stem cell pool. However, the i... Read more »
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Antibody LowCell ChIP kit
MOZ-Mediated Repression of p16(INK) (4) (a) Is Critical for the Sel...
Published: June, 2014
Abstract: Although inhibition of p16(INK4a) expression is critical to preserve the proliferative capacity of stem cells, the molecular mechanisms responsible... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
BRCA2 prevents R-loop accumulation and associates with TREX-2 mRNA ...
Published: June, 2014
Abstract: Genome instability is central to ageing, cancer and other diseases. It is not only proteins involved in DNA replication or the DNA damage response ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Genome editing in the human malaria parasite Plasmodium falciparum ...
Published: June, 2014
Abstract: Genome manipulation in the malaria parasite Plasmodium falciparum remains largely intractable and improved genomic tools are needed to further unde... Read more »
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DNA shearing Bioruptor
CPF-Associated Phosphatase Activity Opposes Condensin-Mediated Chro...
Published: June, 2014
Abstract: Functional links connecting gene transcription and condensin-mediated chromosome condensation have been established in species ranging from prokary... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
New lung cancer panel for high-throughput targeted resequencing.
Published: June, 2014
Abstract: We present a new next-generation sequencing-based method to identify somatic mutations of lung cancer. It is a comprehensive mutation profiling pro... Read more »
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DNA shearing Bioruptor
Increased levels of the long intergenic non-protein coding RNA POU3...
Published: June, 2014
Abstract: BACKGROUND & AIMS: Thousands of long intergenic non-protein coding RNAs (lincRNAs) have been identified in mammals via genome-wide sequencing studi... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Phylogenomics of the plant family Araceae.
Published: June, 2014
Abstract: The biogeography, chromosome number evolution, pollination biology and evolutionary history of the plant family Araceae have recently become much c... Read more »
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DNA shearing Bioruptor
Three-dimensional modeling of the P. falciparum genome during the e...
Published: June, 2014
Abstract: The development of the human malaria parasite Plasmodium falciparum is controlled by coordinated changes in gene expression throughout its complex ... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Engineered zinc-finger transcription factors activate OCT4 (POU5F1)...
Published: June, 2014
Abstract: Artificial transcription factors are powerful tools for regulating gene expression. Here we report results with engineered zinc-finger transcriptio... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Isolation and characterization of novel microsatellite loci in two ...
Published: June, 2014
Abstract: Read more »
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DNA shearing Bioruptor
Hydroxymethylation and DNA methylation profiles in the prefrontal c...
Published: May, 2014
Abstract: 5-Hydroxymethylcytosine (5hmC) is abundant in the brain, suggesting an important role in epigenetic control of neuronal functions. In this paper, w... Read more »
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DNA shearing Bioruptor
SPIB and BATF provide alternate determinants of IRF4 occupancy in d...
Published: May, 2014
Abstract: Interferon regulatory factor 4 (IRF4) is central to the transcriptional network of activated B-cell-like diffuse large B-cell lymphoma (ABC-DLBCL),... Read more »
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Microplex Library Preparation kit
Impacts of TCDD and MeHg on DNA methylation in zebrafish (Danio rer...
Published: May, 2014
Abstract: This study aimed to investigate whether dioxin (TCDD) and methylmercury (MeHg) pose a threat to offspring of fish exposed to elevated concentration... Read more »
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MagMeDIP kit
Membrane-Bound Methyltransferase Complex VapA-VipC-VapB Guides Epig...
Published: May, 2014
Abstract: Epigenetic and transcriptional control of gene expression must be coordinated in response to external signals to promote alternative multicellular ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody
Fat-specific protein 27 inhibits lipolysis by facilitating the inhi...
Published: May, 2014
Abstract: Lipolysis in fat tissue represents a major source of circulating fatty acids. Previously, we have found that lipolysis in adipocytes is controlled ... Read more »
Fat specific protein 27 inhibits lipolysis by facilitating the inhi...
Published: May, 2014
Abstract: Lipolysis in fat tissue represents a major source of circulating fatty acids. Previously, we have found that lipolysis in adipocytes is controlled ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
A genome-wide analysis of Cas9 binding specificity using ChIP-seq a...
Published: May, 2014
Abstract: Clustered regularly interspaced short palindromic repeat (CRISPR) RNA-guided nucleases have gathered considerable excitement as a tool for genome e... Read more »
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DNA shearing Bioruptor

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  • FASEB Biological Methylation: Fundamental Mechanisms
    Porto, Portugal
    Jul 28-Aug 1, 2024
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