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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Therapeutic targeting of BET bromodomain proteins in castration-res...
Published: June, 2014
Abstract: Men who develop metastatic castration-resistant prostate cancer (CRPC) invariably succumb to the disease. Progression to CRPC after androgen ablati... Read more »
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Bioruptor Chromatin Shearing ChIP-seq Antibody HighCell ChIP kit IPure kit
Evaluation of viability-qPCR detection system on viable and dead Sa...
Published: June, 2014
Abstract: The propidium monoazide (PMA) coupled with PCR (viability PCR) is used in foodborne pathogen detection in order to detect only viable bacteria. Ori... Read more »
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Master Mix
Epigenetic regulations of immediate early genes expression involved...
Published: June, 2014
Abstract: We previously demonstrated that APP epigenetically regulates Egr1 expression both in cultured neurons and in vivo. Since Egr1 is an immediate early... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
A Histone Deacetylase Complex Mediates Biofilm Dispersal and Drug R...
Published: June, 2014
Abstract: UNLABELLED: Biofilms are resilient, surface-associated communities of cells with specialized properties (e.g., resistance to drugs and mechanical f... Read more »
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Bioruptor Cell Lysis
RNAi-Mediated Gene silencing in Zebrafish Triggered by Convergent T...
Published: June, 2014
Abstract: RNAi based strategies to induce gene silencing are commonly employed in numerous model organisms but have not been extensively used in zebrafish. W... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody
REGNET: mining context-specific human transcription networks using ...
Published: June, 2014
Abstract: BACKGROUND: Genome-wide expression profiles reflect the transcriptional networks specific to the given cell context. However, most statistical mode... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Corolla Is a Novel Protein that Contributes to the Architecture of ...
Published: June, 2014
Abstract: In most organisms the synaptonemal complex (SC) connects paired homologs along their entire length during much of meiotic prophase. To better under... Read more »
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DNA shearing Bioruptor
SOX2 controls tumour initiation and cancer stem-cell functions in s...
Published: June, 2014
Abstract: Cancer stem cells (CSCs) have been reported in various cancers, including in skin squamous-cell carcinoma (SCC). The molecular mechanisms regulatin... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
COUP-TFI modifies CXCL12 and CXCR4 expression by activating EGF sig...
Published: June, 2014
Abstract: BACKGROUND: The orphan receptors COUP-TF (chicken ovalbumin upstream promoter transcription factor) I and II are members of the nuclear receptor su... Read more »
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Bioruptor Chromatin Shearing
PARG is dispensable for recovery from transient replicative stress ...
Published: June, 2014
Abstract: Poly(ADP-ribosyl)ation is involved in numerous bio-logical processes including DNA repair, transcription and cell death. Cellular levels of poly(AD... Read more »
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Bioruptor Cell Lysis Western Blot Bioruptor Plus
NFAT1 and NFAT3 Cooperate with HDAC4 during Regulation of Alternati...
Published: June, 2014
Abstract: BACKGROUND: The bulk of human genes undergo alternative splicing (AS) upon response to physiological stimuli. AS is a great source of protein diver... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Conservation of streptococcal CRISPRs on human skin and saliva.
Published: June, 2014
Abstract: BACKGROUND: Clustered Regularly Interspaced Short Palindromic Repeats (CRISPRs) are utilized by bacteria to resist encounters with their viruses. H... Read more »
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DNA shearing Bioruptor
Variant PRC1 Complex-Dependent H2A Ubiquitylation Drives PRC2 Recru...
Published: June, 2014
Abstract: Chromatin modifying activities inherent to polycomb repressive complexes PRC1 and PRC2 play an essential role in gene regulation, cellular differen... Read more »
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Bioruptor Chromatin Shearing ChIP-seq Antibody H3K27me3 (C15410069)
Reorganization of enhancer patterns in transition from naive to pri...
Published: June, 2014
Abstract: Naive and primed pluripotency is characterized by distinct signaling requirements, transcriptomes, and developmental properties, but both cellular ... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Retinoblastoma protein (RB) interacts with E2F3 to control terminal...
Published: June, 2014
Abstract: The retinoblastoma protein (RB) is essential for normal cell cycle control. RB function depends, at least in part, on interactions with the E2F fam... Read more »
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Bioruptor Western Blot Tissue Homogenization
Hippo pathway activity influences liver cell fate.
Published: June, 2014
Abstract: The Hippo-signaling pathway is an important regulator of cellular proliferation and organ size. However, little is known about the role of this cas... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The HP1 Homolog Rhino Anchors a Nuclear Complex that Suppresses piR...
Published: June, 2014
Abstract: piRNAs guide an adaptive genome defense system that silences transposons during germline development. The Drosophila HP1 homolog Rhino is required ... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
CETP inhibitors downregulate hepatic LDL receptor and PCSK9 express...
Published: June, 2014
Abstract: BACKGROUND: CETP inhibitors block the transfer of cholesteryl ester from HDL-C to VLDL-C and LDL-C, thereby raising HDL-C and lowering LDL-C. In th... Read more »
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Bioruptor Cell Lysis Western Blot Bioruptor Plus
Deep sequencing reveals new aspects of progesterone receptor signal...
Published: June, 2014
Abstract: Despite the pleiotropic effects of the progesterone receptor in breast cancer, the molecular mechanisms in play remain largely unknown. To gain a g... Read more »
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DNA shearing Bioruptor
Frizzled 7 Expression Is Positively Regulated by SIRT1 and β-Cateni...
Published: June, 2014
Abstract: The Wnt signaling pathway is often chronically activated in diverse human tumors, and the Frizzled (FZD) family of receptors for Wnt ligands, are c... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Insulin regulates carboxypeptidase E by modulating translation init...
Published: June, 2014
Abstract: Insulin resistance, hyperinsulinemia, and hyperproinsulinemia occur early in the pathogenesis of type 2 diabetes (T2D). Elevated levels of proinsul... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Functional Analysis of the TRIB1 Associated Locus Linked to Plasma ...
Published: June, 2014
Abstract: BACKGROUND: The TRIB1 locus has been linked to hepatic triglyceride metabolism in mice and to plasma triglycerides and coronary artery disease in h... Read more »
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Bioruptor Chromatin Shearing
Impact of MLL5 expression on decitabine efficacy and DNA methylatio...
Published: June, 2014
Abstract: Hypomethylating agents are widely used in patients with myelodysplastic syndromes and unfit patients with acute myeloid leukemia. However, it is no... Read more »
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MagMeDIP kit
Chronic alcohol consumption leads to neurochemical changes in the n...
Published: June, 2014
Abstract: Neuropeptide Y (NPY)- and acetylcholine-containing interneurons of the nucleus accumbens (NAc) seem to play a major role in the rewarding effects o... Read more »
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Bioruptor Tissue Homogenization
Differential regulation of Gli proteins by Sufu in the lung affects...
Published: June, 2014
Abstract: Mammalian Hedgehog (Hh) signaling relies on three Gli transcription factors to mediate Hh responses. This process is controlled in part by a major ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
A specific polymorphism in Mycobacterium tuberculosis H37Rv causes ...
Published: June, 2014
Abstract: The ESX-1 secreted virulence factor ESAT-6 is one of the major and most well-studied virulence factors of Mycobacterium tuberculosis given that its... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Seminoma and embryonal carcinoma footprints identified by analysis ...
Published: June, 2014
Abstract: BACKGROUND: Originating from Primordial Germ Cells/gonocytes and developing via a precursor lesion called Carcinoma In Situ (CIS), Germ Cell Cancer... Read more »
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Antibody LowCell ChIP kit H3K4me3 (C15410003) IPure kit
Ezh2 regulates transcriptional and posttranslational expression of ...
Published: June, 2014
Abstract: Acquired aplastic anemia (AA) is a potentially fatal bone marrow (BM) failure syndrome. IFN-γ-producing Th1 CD4(+) T cells mediate the immune destr... Read more »
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Antibody H3K27me3 (C15410069)
Genome-wide characterization reveals complex interplay between TP53...
Published: June, 2014
Abstract: In response to genotoxic stress the TP53 tumour suppressor activates target gene expression to induce cell cycle arrest or apoptosis depending on t... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
The noncoding RNA IPW regulates the imprinted DLK1-DIO3 locus in an...
Published: June, 2014
Abstract: Parental imprinting is a form of epigenetic regulation that results in parent-of-origin differential gene expression. To study Prader-Willi syndrom... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR

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