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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Unraveling vitamin B12-responsive gene regulation in algae.
Published: May, 2014
Abstract: Photosynthetic microalgae play a vital role in primary productivity and biogeochemical cycling in both marine and freshwater systems across the glo... Read more »
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Bioruptor Cell Lysis Western Blot
CD4(+) T cell lineage integrity is controlled by the histone deacet...
Published: May, 2014
Abstract: Molecular mechanisms that maintain lineage integrity of helper T cells are largely unknown. Here we show histone deacetylases 1 and 2 (HDAC1 and HD... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Use of a mouse in vitro fertilization model to understand the devel...
Published: May, 2014
Abstract: The Developmental Origins of Health and Disease hypothesis holds that alterations to homeostasis during critical periods of development can predisp... Read more »
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Antibody
BarR, an Lrp-type transcription factor in Sulfolobus acidocaldarius...
Published: May, 2014
Abstract: In archaea, nothing is known about the β-alanine degradation pathway or its regulation. In this work, we identify and characterize BarR, a novel Lr... Read more »
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IPure kit
Signaling by IL-6 promotes alternative activation of macrophages to...
Published: May, 2014
Abstract: Obesity and resistance to insulin are closely associated with the development of low-grade inflammation. Interleukin 6 (IL-6) is linked to obesity-... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Double-Wall Carbon Nanotubes for Wide-Band, Ultrafast Pulse Generat...
Published: May, 2014
Abstract: We demonstrate wide-band ultrafast optical pulse generation at 1, 1.5, and 2 μm using a single-polymer composite saturable absorber based on double... Read more »
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Bioruptor
Monitoring in vivo reversible cysteine oxidation in proteins using ...
Published: May, 2014
Abstract: Reversible thiol oxidation of cysteine residues occurs in many intracellular catalytic and signaling processes. Here we describe an optimized proto... Read more »
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Bioruptor
Epigenetic changes modulate schistosome egg formation and are a nov...
Published: May, 2014
Abstract: Treatment and control of schistosomiasis relies on the only available drug, praziquantel, and the search for alternative chemotherapeutic agents is... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
R-loops associated with triplet repeat expansions promote gene sile...
Published: May, 2014
Abstract: Friedreich ataxia (FRDA) and Fragile X syndrome (FXS) are among 40 diseases associated with expansion of repeated sequences (TREDs). Although their... Read more »
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DNA shearing Bioruptor
Early aberrant DNA methylation events in a mouse model of acute mye...
Published: April, 2014
Abstract: BACKGROUND: Aberrant DNA methylation is frequently found in human malignancies including acute myeloid leukemia (AML). While most studies focus on ... Read more »
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DNA shearing Bioruptor IP-Star Bioruptor Plus
GATA-dependent regulatory switches establish atrioventricular canal...
Published: April, 2014
Abstract: The embryonic vertebrate heart tube develops an atrioventricular canal that divides the atrial and ventricular chambers, forms atrioventricular con... Read more »
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True MicroChIP kit
Tissue-specific SMARCA4 binding at active and repressed regulatory ...
Published: April, 2014
Abstract: The SMARCA4 (also known as BRG1 in humans) chromatin remodeling factor is critical for establishing lineage-specific chromatin states during early ... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Primary vitamin D receptor target genes as biomarkers for the vitam...
Published: April, 2014
Abstract: Vitamin D3 belongs to the few nutritional compounds that has, via the binding of its metabolite 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3) to the tran... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
Breast tumor specific mutation in GATA3 affects physiological mecha...
Published: April, 2014
Abstract: BACKGROUND: The transcription factor GATA3 is a favorable prognostic indicator in estrogen receptor-alpha (ERalpha)-positive breast tumors in which... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Dynamic ER Interactomes Control the Estrogen-Responsive Trefoil Fac...
Published: April, 2014
Abstract: Estradiol signaling is ideally suited for analyzing molecular and functional linkages between the different layers of information directing transcr... Read more »
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Bioruptor Chromatin Shearing
The ETS family member GABPα modulates androgen receptor signalling ...
Published: April, 2014
Abstract: In prostate cancer (PC), the androgen receptor (AR) is a key transcription factor at all disease stages, including the advanced stage of castrate-r... Read more »
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Bioruptor Cell Lysis Western Blot
IL-13Rα2 mediates PNR-induced migration and metastasis in ERα-negat...
Published: April, 2014
Abstract: Emerging evidence has linked photoreceptor cell-specific nuclear receptor (PNR/NR2E3), an orphan nuclear hormone receptor, to human breast cancer. ... Read more »
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Antibody
Targeting vertebrate intron-encoded box C/D 2'-O-methylation guide ...
Published: April, 2014
Abstract: Post-transcriptional pseudouridylation and 2'-O-methylation of splicesomal small nuclear ribonucleic acids (snRNAs) is mediated by box H/ACA and bo... Read more »
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Bioruptor Cell Lysis Bioruptor Plus
Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian ce...
Published: April, 2014
Abstract: Bacterial type II CRISPR-Cas9 systems have been widely adapted for RNA-guided genome editing and transcription regulation in eukaryotic cells, yet ... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Specificity Protein 1 (Sp1) Maintains Basal Epithelial Expression o...
Published: April, 2014
Abstract: Epithelial-mesenchymal transition (EMT) is required for the specification of tissues during embryonic development and is recapitulated during the m... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Gene-Specific Methylation Control of H3K9 and H3K36 on Neurotrophic...
Published: April, 2014
Abstract: Neural stem cell (NSC) state and fate depend on spatially and temporally synchronized transcriptional and epigenetic regulation of the expression o... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Genome-Wide and Gene-Specific Epigenomic Platforms for Hepatocellul...
Published: April, 2014
Abstract: The majority of the epigenomic reports in hepatocellular carcinoma have focused on identifying novel differentially methylated drivers or passenger... Read more »
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DNA shearing Bioruptor
The CpG Island Encompassing the Promoter and First Exon of Human DN...
Published: April, 2014
Abstract: DNMT3L, a member of DNA methyltransferases family, is present only in mammals. As it provides specificity to the action of de novo methyltransferas... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Stable methylation at promoters distinguishes Epiblast Stem Cells f...
Published: April, 2014
Abstract: Embryonic Stem Cells (ESCs) and Epiblast Stem Cells (EpiSCs) are the in vitro representatives of naïve and primed pluripotency, respectively. ... Read more »
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IP-Star
Context-Selective Death of Acute Myeloid Leukemia Cells Triggered b...
Published: April, 2014
Abstract: HDAC inhibitors (HDACi) are widely used in the clinic to sensitize tumorigenic cells for treatment with other anticancer compounds. The major drawb... Read more »
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Antibody
LSD1 Neurospecific Alternative Splicing Controls Neuronal Excitabil...
Published: April, 2014
Abstract: Alternative splicing in the brain is dynamic and instrumental to adaptive changes in response to stimuli. Lysine-specific demethylase 1 (LSD1/KDM1A... Read more »
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Antibody
CHD7 interacts with BMP R-SMADs to epigenetically regulate cardioge...
Published: April, 2014
Abstract: Haploinsufficiency for CHD7, an ATP-dependent nucleosome remodeling factor, is the leading cause of CHARGE syndrome. While congenital heart defects... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
From Human Monocytes to Genome-Wide Binding Sites - A Protocol for ...
Published: April, 2014
Abstract: Chromatin immunoprecipitation in combination with a genome-wide analysis via high-throughput sequencing is the state of the art method to gain geno... Read more »
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Microplex Library Preparation kit
Suv39h1 mediates AP-2α-dependent inhibition of C/EBPα expression du...
Published: April, 2014
Abstract: Previous studies show that CCAAT/enhancer-binding protein α (C/EBPα) plays a very important role during adipocyte terminal differentiation and that... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Glycolytic genes are targets of the nuclear receptor Ad4BP/SF-1.
Published: April, 2014
Abstract: Genetic deficiencies in transcription factors can lead to the loss of certain types of cells and tissue. The steroidogenic tissue-specific nuclear ... Read more »
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Bioruptor Chromatin Shearing ChIP-seq Bioruptor Plus

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