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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Highly efficient differentiation of embryonic stem cells into adipo...
Published: May, 2014
Abstract: Adipocyte differentiation and function have become the major research targets due to the increasing interest in obesity and related metabolic condi... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
MIR146A inhibits JMJD3 expression and osteogenic differentiation in...
Published: May, 2014
Abstract: Chromatin remodeling is important for cell differentiation. Histone methyltransferase EZH2 and histone demethylase JMJD3 (KDM6B) modulate levels of... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
Reassessment of QTLs for Late Blight Resistance in the Tomato Acces...
Published: May, 2014
Abstract: omato late blight caused by the oomycete pathogen Phytophthora infestans (Mont.) de Bary is a major threat to tomato production in cool and wet env... Read more »
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DNA shearing Bioruptor
The plant metacaspase AtMC1 in pathogen-triggered programmed cell d...
Published: May, 2014
Abstract: Autophagy is a major nutrient recycling mechanism in plants. However, its functional connection with programmed cell death (PCD) is a topic of acti... Read more »
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Bioruptor Cell Lysis
Trrap-dependent histone acetylation specifically regulates cell-cyc...
Published: May, 2014
Abstract: Fate decisions in neural progenitor cells are orchestrated via multiple pathways, and the role of histone acetylation in these decisions has been a... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody LowCell ChIP kit Bioruptor Plus
DNA hypermethylation in prostate cancer is a consequence of aberran...
Published: May, 2014
Abstract: Prostate cancer (CaP) is mostly composed of luminal-like differentiated cells, but contains a small subpopulation of basal cells (including stem-li... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The Ah Receptor Recruits IKKα to Its Target Binding Motifs to Phosp...
Published: May, 2014
Abstract: Aryl hydrocarbon receptor (AHR) activation by xenobiotic ligands such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is key to their toxicity. Follo... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Repression of the Proapoptotic Cellular BIK/NBK Gene by Epstein-Bar...
Published: May, 2014
Abstract: UNLABELLED: The Epstein-Barr virus (EBV) establishes a lifelong latent infection in humans. EBV infection of primary B cells causes cell activation... Read more »
Early-life stress reduces DNA methylation of the pomc gene in male ...
Published: May, 2014
Abstract: Early-life stress (ELS) increases the vulnerability thresholds for stress-related diseases such as major depression and anxiety by inducing alterat... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Estrogen receptor ligands ameliorate fatty liver through a nonclass...
Published: May, 2014
Abstract: UNLABELLED: Liver X receptor (LXR) activation stimulates triglyceride (TG) accumulation in the liver. Several lines of evidence indicate that estra... Read more »
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Antibody
The myc 3' wnt-responsive element suppresses colonic tumorigenesis.
Published: May, 2014
Abstract: Mutations in components of the Wnt/β-catenin signaling pathway are commonly found in colorectal cancers, and these mutations cause aberrant express... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Function-based identification of mammalian enhancers using site-spe...
Published: May, 2014
Abstract: The accurate and comprehensive identification of functional regulatory sequences in mammalian genomes remains a major challenge. Here we describe s... Read more »
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DNA shearing Bioruptor
Unraveling vitamin B12-responsive gene regulation in algae.
Published: May, 2014
Abstract: Photosynthetic microalgae play a vital role in primary productivity and biogeochemical cycling in both marine and freshwater systems across the glo... Read more »
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Bioruptor Cell Lysis Western Blot
CD4(+) T cell lineage integrity is controlled by the histone deacet...
Published: May, 2014
Abstract: Molecular mechanisms that maintain lineage integrity of helper T cells are largely unknown. Here we show histone deacetylases 1 and 2 (HDAC1 and HD... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Use of a mouse in vitro fertilization model to understand the devel...
Published: May, 2014
Abstract: The Developmental Origins of Health and Disease hypothesis holds that alterations to homeostasis during critical periods of development can predisp... Read more »
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Antibody
BarR, an Lrp-type transcription factor in Sulfolobus acidocaldarius...
Published: May, 2014
Abstract: In archaea, nothing is known about the β-alanine degradation pathway or its regulation. In this work, we identify and characterize BarR, a novel Lr... Read more »
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IPure kit
Signaling by IL-6 promotes alternative activation of macrophages to...
Published: May, 2014
Abstract: Obesity and resistance to insulin are closely associated with the development of low-grade inflammation. Interleukin 6 (IL-6) is linked to obesity-... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Double-Wall Carbon Nanotubes for Wide-Band, Ultrafast Pulse Generat...
Published: May, 2014
Abstract: We demonstrate wide-band ultrafast optical pulse generation at 1, 1.5, and 2 μm using a single-polymer composite saturable absorber based on double... Read more »
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Bioruptor
Monitoring in vivo reversible cysteine oxidation in proteins using ...
Published: May, 2014
Abstract: Reversible thiol oxidation of cysteine residues occurs in many intracellular catalytic and signaling processes. Here we describe an optimized proto... Read more »
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Bioruptor
Epigenetic changes modulate schistosome egg formation and are a nov...
Published: May, 2014
Abstract: Treatment and control of schistosomiasis relies on the only available drug, praziquantel, and the search for alternative chemotherapeutic agents is... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
R-loops associated with triplet repeat expansions promote gene sile...
Published: May, 2014
Abstract: Friedreich ataxia (FRDA) and Fragile X syndrome (FXS) are among 40 diseases associated with expansion of repeated sequences (TREDs). Although their... Read more »
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DNA shearing Bioruptor
Early aberrant DNA methylation events in a mouse model of acute mye...
Published: April, 2014
Abstract: BACKGROUND: Aberrant DNA methylation is frequently found in human malignancies including acute myeloid leukemia (AML). While most studies focus on ... Read more »
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DNA shearing Bioruptor IP-Star Bioruptor Plus
GATA-dependent regulatory switches establish atrioventricular canal...
Published: April, 2014
Abstract: The embryonic vertebrate heart tube develops an atrioventricular canal that divides the atrial and ventricular chambers, forms atrioventricular con... Read more »
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True MicroChIP kit
Tissue-specific SMARCA4 binding at active and repressed regulatory ...
Published: April, 2014
Abstract: The SMARCA4 (also known as BRG1 in humans) chromatin remodeling factor is critical for establishing lineage-specific chromatin states during early ... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Primary vitamin D receptor target genes as biomarkers for the vitam...
Published: April, 2014
Abstract: Vitamin D3 belongs to the few nutritional compounds that has, via the binding of its metabolite 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3) to the tran... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
Breast tumor specific mutation in GATA3 affects physiological mecha...
Published: April, 2014
Abstract: BACKGROUND: The transcription factor GATA3 is a favorable prognostic indicator in estrogen receptor-alpha (ERalpha)-positive breast tumors in which... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Dynamic ER Interactomes Control the Estrogen-Responsive Trefoil Fac...
Published: April, 2014
Abstract: Estradiol signaling is ideally suited for analyzing molecular and functional linkages between the different layers of information directing transcr... Read more »
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Bioruptor Chromatin Shearing
The ETS family member GABPα modulates androgen receptor signalling ...
Published: April, 2014
Abstract: In prostate cancer (PC), the androgen receptor (AR) is a key transcription factor at all disease stages, including the advanced stage of castrate-r... Read more »
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Bioruptor Cell Lysis Western Blot
IL-13Rα2 mediates PNR-induced migration and metastasis in ERα-negat...
Published: April, 2014
Abstract: Emerging evidence has linked photoreceptor cell-specific nuclear receptor (PNR/NR2E3), an orphan nuclear hormone receptor, to human breast cancer. ... Read more »
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Antibody
Targeting vertebrate intron-encoded box C/D 2'-O-methylation guide ...
Published: April, 2014
Abstract: Post-transcriptional pseudouridylation and 2'-O-methylation of splicesomal small nuclear ribonucleic acids (snRNAs) is mediated by box H/ACA and bo... Read more »
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Bioruptor Cell Lysis Bioruptor Plus

イベント

  • FASEB Biological Methylation: Fundamental Mechanisms
    Porto, Portugal
    Jul 28-Aug 1, 2024
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