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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian ce...
Published: April, 2014
Abstract: Bacterial type II CRISPR-Cas9 systems have been widely adapted for RNA-guided genome editing and transcription regulation in eukaryotic cells, yet ... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Specificity Protein 1 (Sp1) Maintains Basal Epithelial Expression o...
Published: April, 2014
Abstract: Epithelial-mesenchymal transition (EMT) is required for the specification of tissues during embryonic development and is recapitulated during the m... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Gene-Specific Methylation Control of H3K9 and H3K36 on Neurotrophic...
Published: April, 2014
Abstract: Neural stem cell (NSC) state and fate depend on spatially and temporally synchronized transcriptional and epigenetic regulation of the expression o... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Genome-Wide and Gene-Specific Epigenomic Platforms for Hepatocellul...
Published: April, 2014
Abstract: The majority of the epigenomic reports in hepatocellular carcinoma have focused on identifying novel differentially methylated drivers or passenger... Read more »
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DNA shearing Bioruptor
The CpG Island Encompassing the Promoter and First Exon of Human DN...
Published: April, 2014
Abstract: DNMT3L, a member of DNA methyltransferases family, is present only in mammals. As it provides specificity to the action of de novo methyltransferas... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Stable methylation at promoters distinguishes Epiblast Stem Cells f...
Published: April, 2014
Abstract: Embryonic Stem Cells (ESCs) and Epiblast Stem Cells (EpiSCs) are the in vitro representatives of naïve and primed pluripotency, respectively. ... Read more »
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IP-Star
Context-Selective Death of Acute Myeloid Leukemia Cells Triggered b...
Published: April, 2014
Abstract: HDAC inhibitors (HDACi) are widely used in the clinic to sensitize tumorigenic cells for treatment with other anticancer compounds. The major drawb... Read more »
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Antibody
LSD1 Neurospecific Alternative Splicing Controls Neuronal Excitabil...
Published: April, 2014
Abstract: Alternative splicing in the brain is dynamic and instrumental to adaptive changes in response to stimuli. Lysine-specific demethylase 1 (LSD1/KDM1A... Read more »
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Antibody
CHD7 interacts with BMP R-SMADs to epigenetically regulate cardioge...
Published: April, 2014
Abstract: Haploinsufficiency for CHD7, an ATP-dependent nucleosome remodeling factor, is the leading cause of CHARGE syndrome. While congenital heart defects... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
From Human Monocytes to Genome-Wide Binding Sites - A Protocol for ...
Published: April, 2014
Abstract: Chromatin immunoprecipitation in combination with a genome-wide analysis via high-throughput sequencing is the state of the art method to gain geno... Read more »
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Microplex Library Preparation kit
Suv39h1 mediates AP-2α-dependent inhibition of C/EBPα expression du...
Published: April, 2014
Abstract: Previous studies show that CCAAT/enhancer-binding protein α (C/EBPα) plays a very important role during adipocyte terminal differentiation and that... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Glycolytic genes are targets of the nuclear receptor Ad4BP/SF-1.
Published: April, 2014
Abstract: Genetic deficiencies in transcription factors can lead to the loss of certain types of cells and tissue. The steroidogenic tissue-specific nuclear ... Read more »
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Bioruptor Chromatin Shearing ChIP-seq Bioruptor Plus
Acupuncture Promotes Angiogenesis after Myocardial Ischemia through...
Published: April, 2014
Abstract: BACKGROUND: Acupuncture exerts cardioprotective effects on several types of cardiac injuries, especially myocardial ischemia (MI), but the mechanis... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Histone Deacetylase 1 and p300 Can Directly Associate with Chromati...
Published: April, 2014
Abstract: Lysine acetyltransferases (KATs) and histone deacetylases (HDACs) are important epigenetic modifiers and dynamically cycled on active gene promoter... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Rif1 controls DNA replication timing in yeast through the PP1 phosp...
Published: April, 2014
Abstract: The Rif1 protein, originally identified as a telomere-binding factor in yeast, has recently been implicated in DNA replication control from yeast t... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Epigenetic upregulation of corticotrophin-releasing hormone mediate...
Published: April, 2014
Abstract: Accumulating evidences demonstrated that early postnatal maternal separation induced remarkable social and memory defects in the adult rodents. Ear... Read more »
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DNA shearing Bioruptor Chromatin Shearing ChIP-qPCR
ZBED6 Modulates the Transcription of Myogenic Genes in Mouse Myobla...
Published: April, 2014
Abstract: ZBED6 is a recently discovered transcription factor, unique to placental mammals, that has evolved from a domesticated DNA transposon. It acts as a... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Characterization of an archaeal two-component system that regulates...
Published: April, 2014
Abstract: Two-component signal transduction systems (TCSs) are a major mechanism used by bacteria in response to environmental changes. Although many sequenc... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
The transcription factor E4bp4/Nfil3 controls commitment to the NK ...
Published: April, 2014
Abstract: The transcription factor E4bp4 (Nfil3) is essential for natural killer (NK) cell production. Here, we show that E4bp4 is required at the NK lineage... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Multisite phosphorylation of the Sum1 transcriptional repressor by ...
Published: April, 2014
Abstract: Activation of the meiotic transcription factor Ndt80 is a key regulatory transition in the life-cycle of Saccharomyces cerevisiae because it trigge... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Whole Exome Sequencing Identifies Recessive PKHD1 Mutations in a Ch...
Published: April, 2014
Abstract: BACKGROUND: Mutations in PKHD1 cause autosomal recessive Caroli disease, which is a rare congenital disorder involving cystic dilatation of the int... Read more »
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DNA shearing Bioruptor
Comparative epigenomics in distantly related teleost species identi...
Published: April, 2014
Abstract: The complex relationship between ontogeny and phylogeny has been the subject of attention and controversy since von Baer's formulations in the 19th... Read more »
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Bioruptor Chromatin Shearing ChIP-seq Antibody
YY1 Acts as a Transcriptional Activator of Hoxa5 Gene Expression in...
Published: April, 2014
Abstract: The Hox gene family encodes homeodomain-containing transcriptional regulators that confer positional information to axial and paraxial tissues in t... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
TAL effector-mediated genome visualization (TGV).
Published: April, 2014
Abstract: The three-dimensional remodeling of chromatin within nucleus is being recognized as determinant for genome regulation. Recent technological advance... Read more »
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Antibody
Protein quantitative trait Loci identify novel candidates modulatin...
Published: April, 2014
Abstract: Annotating and interpreting the results of genome-wide association studies (GWAS) remains challenging. Assigning function to genetic variants as ex... Read more »
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Bioruptor Cell Lysis
USP7 attenuates hepatic gluconeogenesis through modulation of FoxO1...
Published: April, 2014
Abstract: Hepatic forkhead protein FoxO1 is a key component of systemic glucose homeostasis via its ability to regulate the transcription of rate-limiting en... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Intronic DNA elements regulate Nrf-2 chemical responsiveness of the...
Published: April, 2014
Abstract: In humans, microsomal epoxide hydrolase (mEH) contributes important biological functions that underlie both detoxification and bioactivation fates ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
ApoER2 processing by presenilin-1 modulates reelin expression.
Published: April, 2014
Abstract: The reelin signaling protein and its downstream components have been associated with synaptic plasticity and neurotransmission. The reelin signalin... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
LORD-Q: a long-run real-time PCR-based DNA-damage quantification me...
Published: April, 2014
Abstract: DNA damage is tightly associated with various biological and pathological processes, such as aging and tumorigenesis. Although detection of DNA dam... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Length-dependent processing of telomeres in the absence of telomerase.
Published: April, 2014
Abstract: In the absence of telomerase, telomeres progressively shorten with every round of DNA replication, leading to replicative senescence. In telomerase... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR

イベント

  • FASEB Biological Methylation: Fundamental Mechanisms
    Porto, Portugal
    Jul 28-Aug 1, 2024
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