Publications,References

SIRT6 is required for maintenance of telomere position effect in hu...
Published: August, 2011

Abstract: In Saccharomyces cerevisiae, the repressive chromatin environment at telomeres gives rise to telomere position effect (TPE), the epigenetic silenci... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Exome sequencing identifies a DYNC1H1 mutation in a large pedigree ...
Published: August, 2011

Abstract: Charcot-Marie-Tooth disease is characterized by length-dependent axonal degeneration with distal sensory loss and weakness, deep-tendon-reflex abno... Read more »

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DNA shearing Bioruptor

The tumour antigen PRAME is a subunit of a Cul2 ubiquitin ligase an...
Published: August, 2011

Abstract: The human tumour antigen PRAME (preferentially expressed antigen of melanoma) is frequently overexpressed in tumours. High PRAME levels correlate w... Read more »

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Bioruptor Chromatin Shearing ChIP-seq Antibody

Carboxyl-terminal truncated HBx regulates a distinct microRNA trans...
Published: August, 2011

Abstract: BACKGROUND: The biological pathways and functional properties by which misexpressed microRNAs (miRNAs) contribute to liver carcinogenesis have been... Read more »

The X-inactivation trans-activator Rnf12 is negatively regulated by...
Published: August, 2011

Abstract: X-inactivation, the molecular mechanism enabling dosage compensation in mammals, is tightly controlled during mouse early embryogenesis. In the mor... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

EVI1-mediated down regulation of MIR449A is essential for the survi...
Published: August, 2011

Abstract: Chromosomal rearrangements involving the MECOM (MDS1 and EVI1 complex) locus are recurrent genetic events in myeloid leukaemia and are associated w... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR HighCell ChIP kit

Polycomb eviction as a new distant enhancer function.
Published: August, 2011

Abstract: Remote distal enhancers may be located tens or thousands of kilobases away from their promoters. How they control gene expression is still poorly u... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Long-range epigenetic silencing associates with deregulation of Ika...
Published: August, 2011

Abstract: Transcription factors are common targets of epigenetic inactivation in human cancer. Promoter hypermethylation and subsequent silencing of transcri... Read more »

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Bioruptor Chromatin Shearing

Systematic bias in high-throughput sequencing data and its correcti...
Published: August, 2011

Abstract: Genomic sequences obtained through high-throughput sequencing are not uniformly distributed across the genome. For example, sequencing data of tota... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Histone tails regulate DNA methylation by allosterically activating...
Published: August, 2011

Abstract: Cytosine methylation of genomic DNA controls gene expression and maintains genome stability. How a specific DNA sequence is targeted for methylatio... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Analysis of HP1α regulation in human breast cancer cells.
Published: August, 2011

Abstract: The three mammalian HP1 proteins, HP1α/CBX5, HP1β/CBX1, and HPγ/CBX3, are involved in chromatin packing and gene regulation. The HP1α protein is do... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Coordination of KSHV latent and lytic gene control by CTCF-cohesin ...
Published: August, 2011

Abstract: Herpesvirus persistence requires a dynamic balance between latent and lytic cycle gene expression, but how this balance is maintained remains enigm... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Gcn5 facilitates Pol II progression, rather than recruitment to nuc...
Published: August, 2011

Abstract: In the fission yeast, the MAP kinase Sty1 and the transcription factor Atf1 regulate up to 400 genes in response to environmental signals, and both... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Mammalian Gcm genes induce Hes5 expression by active DNA demethylat...
Published: August, 2011

Abstract: Signaling mediated by Notch receptors is crucial for the development of many organs and the maintenance of various stem cell populations. The activ... Read more »

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LowCell ChIP kit

Temporal uncoupling of the DNA methylome and transcriptional repres...
Published: August, 2011

Abstract: DNA methylation is a tightly regulated epigenetic mark associated with transcriptional repression. Next-generation sequencing of purified methylate... Read more »

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MeDIP kit

IL-20 is epigenetically regulated in NSCLC and down regulates the e...
Published: August, 2011

Abstract: BACKGROUND: IL-20 is a pleiotrophic member of the IL-10 family and plays a role in skin biology and the development of haematopoietic cells. Recent... Read more »

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Antibody H3K4me3 (C15410003)

Methyl-binding domain protein 2-dependent proliferation and surviva...
Published: August, 2011

Abstract: Methyl cytosine binding domain protein 2 (MBD2) has been shown to bind to and mediate repression of methylated tumor suppressor genes in cancer cel... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Transcription initiation platforms and GTF recruitment at tissue-sp...
Published: August, 2011

Abstract: Recent work has shown that RNA polymerase (Pol) II can be recruited to and transcribe distal regulatory regions. Here we analyzed transcription ini... Read more »

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Antibody

Suppl. information - Transcription initiation platforms and GTF rec...
Published: August, 2011

Abstract: Recent work has shown that RNA polymerase (Pol) II can be recruited to and transcribe distal regulatory regions. Here we analyzed transcription ini... Read more »

msl2 mRNA is bound by free nuclear MSL complex in Drosophila melano...
Published: August, 2011

Abstract: In Drosophila, the global increase in transcription from the male X chromosome to compensate for its monosomy is mediated by the male-specific leth... Read more »

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Bioruptor

Reciprocal regulation of human immunodeficiency virus-1 gene expres...
Published: July, 2011

Abstract: Cellular heat shock proteins (Hsps) are induced upon heat shock, UV irradiation and microbial or viral infection. They are also known to be involve... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Regulation of adipocyte differentiation by the zinc finger protein ...
Published: July, 2011

Abstract: Zinc finger proteins constitute the largest family of transcription regulators in eukaryotes. These factors are involved in diverse processes in ma... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Negative regulation of HIV-1 transcription by a heterodimeric NF-κB...
Published: July, 2011

Abstract: Signal transducers and activator of transcription (STAT) proteins are often constitutively activated in leukocytes of HIV-1(+) individuals, which f... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Rtt107 is required for recruitment of the SMC5/6 complex to DNA dou...
Published: July, 2011

Abstract: Genome integrity is maintained by a network of DNA damage response pathways, including checkpoints and DNA repair processes. In Saccharomyces cerev... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Defective GATA-3 expression in Th2 LCR-deficient mice.
Published: July, 2011

Abstract: Th2 cell differentiation is critically influenced by transcription factor GATA-3 and by various cis-acting elements including enhancers, silencers ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Transcription factors KLF1 and KLF2 positively regulate embryonic a...
Published: July, 2011

Abstract: Krüppel-like factors (KLFs) control cell differentiation and embryonic development. KLF1 (erythroid Krüppel-like factor) plays essential roles in e... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Cap2-HAP complex is a critical transcriptional regulator that has d...
Published: July, 2011

Abstract: Iron homeostasis is highly regulated in organisms across evolutionary time scale as iron is essential for various cellular processes. In a computat... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus

Hyperexpansion of GAA repeats affects post-initiation steps of FXN ...
Published: July, 2011

Abstract: Friedreich's ataxia (FRDA) is caused by biallelic expansion of GAA repeats leading to the transcriptional silencing of the frataxin (FXN) gene. The... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Human mediator subunit MED26 functions as a docking site for transc...
Published: July, 2011

Abstract: Promoter-proximal pausing by initiated RNA polymerase II (Pol II) and regulated release of paused polymerase into productive elongation has emerged... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Transcription factor T-bet represses expression of the inhibitory r...
Published: July, 2011

Abstract: T cell exhaustion has a major role in failure to control chronic infection. High expression of inhibitory receptors, including PD-1, and the inabil... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

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