Publications,References

Human mediator subunit MED26 functions as a docking site for transc...
Published: July, 2011

Abstract: Promoter-proximal pausing by initiated RNA polymerase II (Pol II) and regulated release of paused polymerase into productive elongation has emerged... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Transcription factor T-bet represses expression of the inhibitory r...
Published: July, 2011

Abstract: T cell exhaustion has a major role in failure to control chronic infection. High expression of inhibitory receptors, including PD-1, and the inabil... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Cell type-specific DNA methylation at intragenic CpG islands in the...
Published: July, 2011

Abstract: Human and mouse genomes contain a similar number of CpG islands (CGIs), which are discrete CpG-rich DNA sequences associated with transcription sta... Read more »

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DNA shearing Bioruptor

Extensive and coordinated transcription of noncoding RNAs within ce...
Published: July, 2011

Abstract: Transcription of long noncoding RNAs (lncRNAs) within gene regulatory elements can modulate gene activity in response to external stimuli, but the ... Read more »

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Bioruptor

H3K9 histone acetylation predicts pluripotency and reprogramming ca...
Published: July, 2011

Abstract: The pluripotent genome is characterized by unique epigenetic features and a decondensed chromatin conformation. However, the relationship between e... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Hyphal development in Candida albicans requires two temporally link...
Published: July, 2011

Abstract: Phenotypic plasticity is common in development. For Candida albicans, the most common cause of invasive fungal infections in humans, morphological ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

RETINOBLASTOMA-RELATED PROTEIN controls the transition to autotroph...
Published: July, 2011

Abstract: Seedling establishment is a crucial phase during plant development when the germinating heterotrophic embryo switches to autotrophic growth and dev... Read more »

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LowCell ChIP kit

Activation of group II metabotropic glutamate receptors promotes DN...
Published: July, 2011

Abstract: Activation of group II metabotropic glutamate receptors (mGlu2 and -3 receptors) has shown a potential antipsychotic activity, yet the underlying m... Read more »

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MagMeDIP kit

Association of Rex-1 to target genes supports its interaction with ...
Published: July, 2011

Abstract: Rex-1/Zfp42 displays a remarkably restricted pattern of expression in preimplantation embryos, primary spermatocytes, and undifferentiated mouse em... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

SeqGene: a comprehensive software solution for mining exome- and tr...
Published: June, 2011

Abstract: BACKGROUND: The popularity of massively parallel exome and transcriptome sequencing projects demands new data mining tools with a comprehensive set... Read more »

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DNA shearing Bioruptor

DNA methylation status predicts cell type-specific enhancer activity
Published: June, 2011

Abstract: Cell-selective glucocorticoid receptor (GR) binding to distal regulatory elements is associated with cell type-specific regions of locally accessib... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

5-Hydroxymethylcytosine is associated with enhancers and gene bodie...
Published: June, 2011

Abstract: BACKGROUND: 5-Hydroxymethylcytosine (5hmC) was recently found to be abundantly present in certain cell types, including embryonic stem cells. There... Read more »

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Antibody

Occupancy of chromatin organizers in the Epstein-Barr virus genome.
Published: June, 2011

Abstract: The human CCCTC-binding factor, CTCF, regulates transcription of the double-stranded DNA genomes of herpesviruses. The architectural complex cohesi... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Early-stage formation of an epigenetic field defect in a mouse coli...
Published: June, 2011

Abstract: Epigenetic fields for cancerization are involved in development of human cancers, especially those associated with inflammation and multiple occurr... Read more »

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Antibody

Mutations in ZBTB24 are associated with immunodeficiency, centromer...
Published: June, 2011

Abstract: Autosomal-recessive immunodeficiency, centromeric instability, and facial anomalies (ICF) syndrome is mainly characterized by recurrent, often fata... Read more »

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DNA shearing Bioruptor

Human teneurin-1 is a direct target of the homeobox transcription f...
Published: June, 2011

Abstract: BACKGROUND: Teneurin-1 is a member of a family of type II transmembrane proteins conserved from C.elegans to vertebrates. Teneurin expression in ve... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Effects of epigenetic-based anti-cancer drugs in leukemia and multi...
Published: June, 2011

Abstract: Here, we focused on epigenetic changes in leukemia and multiple myeloma (MM) cells. We show how the histone signature, DNA methylation, and levels ... Read more »

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MeDIP kit

Maps of open chromatin guide the functional follow-up of genome-wid...
Published: June, 2011

Abstract: Turning genetic discoveries identified in genome-wide association (GWA) studies into biological mechanisms is an important challenge in human genet... Read more »

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Bioruptor Chromatin Shearing

Coxsackie and adenovirus receptor is a target and a mediator of est...
Published: June, 2011

Abstract: The involvement of the coxsackie and adenovirus receptor (CAR), an adhesion molecule known to be the main determinant of adenovirus transduction of... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Enhancer of Zeste 2 (EZH2) is up-regulated in malignant gliomas and...
Published: June, 2011

Abstract: AIMS: Proteins of the Polycomb repressive complex 2 (PRC2) are epigenetic gene silencers and are involved in tumour development. Their oncogenic fu... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Antibody

A genome-wide search for promoters that respond to increased MYCN r...
Published: June, 2011

Abstract: MYCN is a major driver of neuroblastoma tumorigenesis and MYCN amplification is the worst prognostic indicator of aggressive NB. To identify potent... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

How chromatin is remodelled during DNA repair of UV-induced DNA dam...
Published: June, 2011

Abstract: Global genome nucleotide excision repair removes DNA damage from transcriptionally silent regions of the genome. Relatively little is known about t... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Dynamic chromatin localization of Sirt6 shapes stress- and aging-re...
Published: June, 2011

Abstract: The sirtuin Sirt6 is a NAD-dependent histone deacetylase that is implicated in gene regulation and lifespan control. Sirt6 can interact with the st... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Mediator influences telomeric silencing and cellular life span.
Published: June, 2011

Abstract: The Mediator complex is required for the regulated transcription of nearly all RNA polymerase II-dependent genes. Here we demonstrate a new role fo... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Human imprinted retrogenes exhibit non-canonical imprint chromatin ...
Published: June, 2011

Abstract: Imprinted retrotransposed genes share a common genomic organization including a promoter-associated differentially methylated region (DMR) and a po... Read more »

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DNA shearing Bioruptor

Circumventing heterozygosity: sequencing the amplified genome of a ...
Published: June, 2011

Abstract: Heterozygosity is a major challenge to efficient, high-quality genomic assembly and to the full genomic survey of polymorphism and divergence. In D... Read more »

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DNA shearing Bioruptor

LSD1 regulates the balance between self-renewal and differentiation...
Published: June, 2011

Abstract: We identify LSD1 (lysine-specific demethylase 1; also known as KDM1A and AOF2) as a key histone modifier that participates in the maintenance of pl... Read more »

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Antibody

H3.5 is a novel hominid-specific histone H3 variant that is specifi...
Published: June, 2011

Abstract: The incorporation of histone variants into chromatin plays an important role for the establishment of particular chromatin states. Six human histon... Read more »

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Antibody H3K4me3 (C15410003)

Pre-TCR signaling and CD8 gene bivalent chromatin resolution during...
Published: June, 2011

Abstract: The CD8 gene is silent in CD4(-)CD8(-) double-negative thymocytes, expressed in CD4(+)CD8(+) double-positive cells, and silenced in cells committin... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Reversible epigenetic fingerprint-mediated glutathione-S-transferas...
Published: June, 2011

Abstract: Glutathione-S-transferase P1 (GSTP1) gene is commonly silenced by CpG island promoter hypermethylation in prostate, breast, and liver cancers. Howe... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Cell Lysis Enzymatic Assay

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