Publications,References

Adaptation to P element transposon invasion in Drosophila melanogas...
Published: December, 2011

Abstract: Transposons evolve rapidly and can mobilize and trigger genetic instability. Piwi-interacting RNAs (piRNAs) silence these genome pathogens, but it ... Read more »

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DNA shearing Bioruptor

Caenorhabditis elegans Heterochromatin Protein 1 (HPL-2) links deve...
Published: December, 2011

Abstract: ABSTRACT: BACKGROUND: Heterochromatin protein 1 (HP1) family proteins have a well-characterized role in heterochromatin packaging and gene regulat... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Characterization of a proximal Sp1 response element in the mouse Dl...
Published: December, 2011

Abstract: ABSTRACT: BACKGROUND: DLK2 is an EGF-like membrane protein, closely related to DLK1, which is involved in adipogenesis. Both proteins interact wit... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

A small molecule differentiation inducer increases insulin producti...
Published: December, 2011

Abstract: New drugs for preserving and restoring pancreatic β-cell function are critically needed for the worldwide epidemic of type 2 diabetes and the cure ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Second order regulator Collier directly controls intercalary-specif...
Published: December, 2011

Abstract: In Drosophila, trunk metamerization is established by a cascade of segmentation gene activities: the gap genes, the pair rule genes, and the segmen... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Regulation of cell growth by Notch signaling and its differential r...
Published: December, 2011

Abstract: Cancer stem cells (CSCs) are postulated to be a small subset of tumor cells with tumor-initiating ability that shares features with normal tissue-s... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

cAMP response element-binding protein is a primary hub of activity-...
Published: December, 2011

Abstract: Long-lasting forms of neuronal plasticity require de novo gene expression, but relatively little is known about the events that occur genome-wide i... Read more »

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Bioruptor Cell Lysis Western Blot

Prepatterning of developmental gene expression by modified histones...
Published: December, 2011

Abstract: A hallmark of anamniote vertebrate development is a window of embryonic transcription-independent cell divisions before onset of zygotic genome act... Read more »

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Antibody H3K4me3 (C15410003) H3K27me3 (C15410069)

The Chromatin Binding Protein HMGN1 Regulates the Expression of Met...
Published: December, 2011

Abstract: High Mobility Group N1 protein (HMGN1), a nucleosomal binding protein that affects the structure and function of chromatin, is encoded by a gene lo... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Genome-wide profiling of LXR, RXR and PPARα in mouse liver reveals ...
Published: December, 2011

Abstract: The liver X receptors (LXRs) are nuclear receptors that form permissive heterodimers with retinoid X receptor (RXR) and are important regulators of... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Antibody

Bio-CAP: a versatile and highly sensitive technique to purify and c...
Published: December, 2011

Abstract: Across vertebrate genomes methylation of cytosine residues within the context of CpG dinucleotides is a pervasive epigenetic mark that can impact g... Read more »

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DNA shearing Bioruptor

Tracheobronchial transplantation with a stem-cell-seeded bioartific...
Published: December, 2011

Abstract: BACKGROUND: Tracheal tumours can be surgically resected but most are an inoperable size at the time of diagnosis; therefore, new therapeutic optio... Read more »

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Antibody LowCell ChIP kit

Comprehensive genome-wide protein-DNA interactions detected at sing...
Published: December, 2011

Abstract: Chromatin immunoprecipitation (ChIP-chip and ChIP-seq) assays identify where proteins bind throughout a genome. However, DNA contamination and DNA ... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

A distinct mechanism for coactivator versus corepressor function by...
Published: December, 2011

Abstract: Histone methyltransferase G9a has been understood primarily as a corepressor of gene expression, but we showed previously that G9a positively regul... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Notch Activation of Jagged1 Contributes to the Assembly of the Arte...
Published: December, 2011

Abstract: BACKGROUND: Notch signaling in vascular smooth muscle precursors is required for smooth muscle differentiation. Jagged1 expression on endothelium ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

NuRD-mediated deacetylation of H3K27 facilitates recruitment of Pol...
Published: December, 2011

Abstract: Pluripotent cells possess the ability to differentiate into any cell type. Commitment to differentiate into specific lineages requires strict contr... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

DNA methylation regulates the expression of CXCL12 in rheumatoid ar...
Published: December, 2011

Abstract: In the search for specific genes regulated by DNA methylation in rheumatoid arthritis (RA), we investigated the expression of CXCL12 in synovial fi... Read more »

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DNA shearing Bioruptor

A simple method for the parallel deep sequencing of full influenza ...
Published: December, 2011

Abstract: Given the major threat of influenza A to human and animal health, and its ability to evolve rapidly through mutation and reassortment, tools that e... Read more »

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DNA shearing Bioruptor

Etsrp/Etv2 Is Directly Regulated by Foxc1a/b in the Zebrafish Angio...
Published: December, 2011

Abstract: Rationale:Endothelial cells are developmentally derived from angioblasts specified in the mesodermal germ cell layer. The transcription factor etsr... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Mechanisms and functions of Tet protein-mediated 5-methylcytosine o...
Published: December, 2011

Abstract: Ten-eleven translocation 1-3 (Tet1-3) proteins have recently been discovered in mammalian cells to be members of a family of DNA hydroxylases that ... Read more »

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Antibody

Novel insights into the regulation of antioxidant-response-element-...
Published: December, 2011

Abstract: A central mechanism in cellular defence against oxidative or electrophilic stress is mediated by transcriptional induction of genes via the ARE (an... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Role of farnesoid X receptor (FXR) in the process of differentiatio...
Published: December, 2011

Abstract: Bone tissue contains bile acids which accumulate from serum and which can be released in large amounts in the bone microenvironment during bone res... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Notch1 binds and induces degradation of Snail in hepatocellular car...
Published: November, 2011

Abstract: BACKGROUND: Hepatocellular carcinoma (HCC) is a common, highly invasive malignant tumor associated with a high mortality rate. We previously report... Read more »

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Bioruptor Cell Lysis Enzymatic Assay

Systematic comparison of three methods for fragmentation of long-ra...
Published: November, 2011

Abstract: Next Generation Sequencing (NGS) technologies are gaining importance in the routine clinical diagnostic setting. It is thus desirable to simplify t... Read more »

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DNA shearing Bioruptor

Distinct Epigenomic Features in End-Stage Failing Human Hearts
Published: November, 2011

Abstract: Background—The epigenome refers to marks on the genome, including DNA methylation and histone modifications, that regulate the expression of underl... Read more »

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DNA shearing Bioruptor Chromatin Shearing ChIP-seq Antibody

Generation and characterization of rat and mouse monoclonal antibod...
Published: November, 2011

Abstract: Methyl CpG binding protein 2 (MeCP2) binds DNA, and has a preference for methylated CpGs and, hence, in cells, it accumulates in heterochromatin. E... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Epigenetic inactivation of paired box gene 5, a novel tumor suppres...
Published: November, 2011

Abstract: Using genome-wide methylation screening, we identified that paired box gene 5 (PAX5) is involved in human cancer development. However, the function... Read more »

Expression profile of the sphingosine kinase signalling system in t...
Published: November, 2011

Abstract: AIMS: Chronic obstructive pulmonary disease (COPD) is a leading cause of death worldwide. Despite its importance, treatment methods are limited and... Read more »

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Bioruptor Cell Lysis Enzymatic Assay

Genomic Maps of Long Noncoding RNA Occupancy Reveal Principles of R...
Published: November, 2011

Abstract: Long noncoding RNAs (lncRNAs) are key regulators of chromatin state, yet the nature and sites of RNA-chromatin interaction are mostly unknown. Here... Read more »

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Bioruptor Chromatin Shearing

Prostacyclin Synthase Expression and Epigenetic Regulation in Nonsm...
Published: November, 2011

Abstract: BACKGROUND: Prostacyclin synthase (PGIS) metabolizes prostaglandin H(2), into prostacyclin. This study aimed to determine the expression profile o... Read more »

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