Publications,References

Large-scale methylation domains mark a functional subset of neurona...
Published: October, 2011

Abstract: DNA methylation is essential for embryonic and neuronal differentiation, but the function of most genomic DNA methylation marks is poorly understoo... Read more »

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DNA shearing Bioruptor

Targeted bisulfite sequencing by solution hybrid selection and mass...
Published: October, 2011

Abstract: We applied a solution hybrid selection approach to the enrichment of CpG islands (CGIs) and promoter sequences from the human genome for targeted h... Read more »

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DNA shearing Bioruptor

Translocation-capture sequencing reveals the extent and nature of c...
Published: September, 2011

Abstract: Chromosomal rearrangements, including translocations, require formation and joining of DNA double strand breaks (DSBs). These events disrupt the in... Read more »

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DNA shearing Bioruptor

A Protein Epitope Signature Tag (PrEST) Library Allows SILAC-based ...
Published: September, 2011

Abstract: Mass spectrometry-based proteomics increasingly relies on relative or absolute quantification. In relative quantification, stable isotope based met... Read more »

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Bioruptor Cell Lysis

DNA-end capping by the budding yeast transcription factor and subte...
Published: September, 2011

Abstract: Telomere repeats in budding yeast are maintained at a constant average length and protected (‘capped’), in part, by mechanisms involving the TG13 ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Histone tail acetylation in brain occurs in an unpredictable fashio...
Published: September, 2011

Abstract: Histone acetylation plays a role in the regulation of gene transcription. Yet it is not known whether post-mortem brain tissue is suitable for the ... Read more »

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Antibody LowCell ChIP kit

An evolutionarily conserved kernel of gata5, gata6, otx2 and prdm1a...
Published: September, 2011

Abstract: An evolutionarily conserved subcircuit (kernel) dedicated to a specific developmental function is found at the top of the gene regulatory networks ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Studying RNA–Protein Interactions In Vivo By RNA Immunoprecipitation
Published: September, 2011

Abstract: The crucial roles played by RNA-binding proteins in all aspects of RNA metabolism, particularly in the regulation of transcription, have become inc... Read more »

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Bioruptor

Reciprocal repression between Sox3 and snail transcription factors ...
Published: September, 2011

Abstract: In developing amniote embryos, the first epithelial-to-mesenchymal transition (EMT) occurs at gastrulation, when a subset of epiblast cells moves t... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Antibody

Glutathione-S-transferase pi 1(GSTP1) gene silencing in prostate ca...
Published: September, 2011

Abstract: Gene silencing by epigenetic mechanisms is frequent in prostate cancer (PCA). The link between DNA hypermethylation and histone modifications is no... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Antibody

BRCA1 tumour suppression occurs via heterochromatin-mediated silenc...
Published: September, 2011

Abstract: Mutations in the tumour suppressor gene BRCA1 lead to breast and/or ovarian cancer. Here we show that loss of Brca1 in mice results in transcriptio... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Rapid, massively parallel single-cell drug response measurements vi...
Published: September, 2011

Abstract: A central question in cancer therapy is how individual cells within a population of tumor cells respond to drugs designed to arrest their growth. H... Read more »

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Master Mix

Silencing of Kruppel-like factor 2 by the histone methyltransferase...
Published: September, 2011

Abstract: The Kruppel-like factor (KLF) proteins are multitasked transcriptional regulators with an expanding tumor suppressor function. KLF2 is one of the p... Read more »

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Antibody H3K27me3 (C15410069)

Interaction of Arabidopsis DET1 with CCA1 and LHY in mediating tran...
Published: September, 2011

Abstract: The COP10-DET1-DDB1 (CDD) complex is an evolutionarily conserved protein complex discovered for its role in the repression of photomorphogenesis in... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Diverse roles of RNA polymerase II-associated factor 1 complex in d...
Published: September, 2011

Abstract: Transcription-coupled repair (TCR) and global genomic repair (GGR) are two pathways of nucleotide excision repair (NER). In Saccharomyces cerevisia... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Regulation of human epidermal stem cell proliferation and senescenc...
Published: September, 2011

Abstract: Human epidermal stem cells transit from a slow cycling to an actively proliferating state to contribute to homeostasis. Both stem cell states diffe... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Genome-wide maps of histone modifications unwind in vivo chromatin ...
Published: September, 2011

Abstract: Using mouse skin, where bountiful reservoirs of synchronized hair follicle stem cells (HF-SCs) fuel cycles of regeneration, we explore how adult SC... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

The transcription factor FOXM1 is a cellular target of the natural ...
Published: September, 2011

Abstract: Transcription factors are proteins that bind specifically to defined DNA sequences to promote gene expression. Targeting transcription factors with... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Disruption of the histone acetyltransferase MYST4 leads to a Noonan...
Published: September, 2011

Abstract: Epigenetic regulation of gene expression, through covalent modification of histones, is a key process controlling growth and development. According... Read more »

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Bioruptor Chromatin Shearing Antibody LowCell ChIP kit

Genome-scale analysis of metazoan replication origins reveals their...
Published: September, 2011

Abstract: In metazoans, thousands of DNA replication origins (Oris) are activated at each cell cycle. Their genomic organization and their genetic nature rem... Read more »

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Bioruptor Chromatin Shearing

Improved quantitative and qualitative production of single-domain i...
Published: September, 2011

Abstract: Camelidae single domain antibodies (VHHs) have structural and binding features that render them suitable alternatives to conventional IgG antibodie... Read more »

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Bioruptor Cell Lysis

Epigenetic regulation of DNA methyltransferases: DNMT1 and DNMT3B i...
Published: September, 2011

Abstract: The role of epigenetics and significance of aberrant gene regulation in etiology of cancer is a well-established phenomenon. The hallmark of cancer... Read more »

Lineage-specific distribution of high levels of genomic 5-hydroxyme...
Published: September, 2011

Abstract: Methylation of cytosine is a DNA modification associated with gene repression. Recently, a novel cytosine modification, 5-hydroxymethylcytosine (5-... Read more »

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Antibody

Smad3-mediated upregulation of miR-21 promotes renal fibrosis.
Published: September, 2011

Abstract: TGF-β/Smad signaling plays a role in fibrogenesis, but therapies targeting TGF-β are ineffective in treating renal fibrosis. Here, we explored the ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

PROMoter uPstream Transcripts share characteristics with mRNAs and ...
Published: September, 2011

Abstract: PROMoter uPstream Transcripts (PROMPTs) were identified as a new class of human RNAs, which are heterologous in length and produced only upstream o... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Effects of genome architecture and epigenetic factors on susceptibi...
Published: September, 2011

Abstract: Aberrant DNA methylation is induced at specific promoter CpG islands (CGIs) in contrast with mutations. The specificity is influenced by genome arc... Read more »

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Antibody

High-throughput sequencing of complete human mtDNA genomes from the...
Published: September, 2011

Abstract: To investigate the demographic history of human populations from the Caucasus and surrounding regions, we used high-throughput sequencing to genera... Read more »

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DNA shearing Bioruptor

Coactivation of GR and NFKB alters the repertoire of their binding ...
Published: September, 2011

Abstract: Glucocorticoid receptor (GR) exerts anti-inflammatory action in part by antagonizing proinflammatory transcription factors such as the nuclear fact... Read more »

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Antibody

Differential patterns of intronic and exonic DNA regions with respe...
Published: August, 2011

Abstract: ABSTRACT: BACKGROUND: The generation of mature mRNAs involves interconnected processes, including transcription by RNA polymerase II (Pol II), mod... Read more »

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Bioruptor Chromatin Shearing

Anthracyclines induce the accumulation of mutant p53 through E2F1-d...
Published: August, 2011

Abstract: Mutant p53 frequently accumulates in cancer cells and promotes tumor cell invasion, as part of its gain of function. Its accumulation is partially ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

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