Publications,References

Determinants of heritable gene silencing for KRAB-dCas9 + DNMT3and ...
Published: April, 2022

Abstract: Precision epigenome editing has gained significant attention as a method to modulate gene expression without altering genetic information. However,... Read more »

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Antibody

Broad domains of histone marks in the highly compact macronuclearg...
Published: April, 2022

Abstract: The unicellular ciliate contains a large vegetative macronucleus with several unusual characteristics, including an extremely high coding density a... Read more »

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Antibody iDeal ChIP-seq Kit for Histones

CREBBP/EP300 acetyltransferase inhibition disrupts FOXA1-bound enha...
Published: March, 2022

Abstract: Therapeutic targeting of the estrogen receptor (ER) is a clinically validated approach for estrogen receptor positive breast cancer (ER+ BC), but s... Read more »

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IP-Star Antibody Microplex Library Preparation kit iDeal ChIP-seq Kit for Histones Chromatin Profiling (ChIP-seq) Services

Haplotype-resolved Chinese male genome assembly based on high-fidel...
Published: March, 2022

Abstract: The advantages of both the length and accuracy of high-fidelity (HiFi) reads enable chromosome-scale haplotype-resolved genome assembly. In this st... Read more »

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Megaruptor

GBS-MeDIP: A protocol for parallel identification of genetic andepi...
Published: March, 2022

Abstract: The GBS-MeDIP protocol combines two previously described techniques, Genotype-by-Sequencing (GBS) and Methylated-DNA-Immunoprecipitation (MeDIP). O... Read more »

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Antibody

H3K9 dimethylation safeguards cancer cells against activation of th...
Published: March, 2022

Abstract: Activation of interferon genes constitutes an important anticancer pathway able to restrict proliferation of cancer cells. Here, we demonstrate tha... Read more »

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Antibody

Complex regulatory role of DNA methylation in caste- and age-specif...
Published: March, 2022

Abstract: The reproductive castes of eusocial insects are often characterised by extreme lifespans and reproductive output, indicating an absence of the fecu... Read more »

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Evaluation of N6-adenine DNA-immunoprecipitation-basedgenomic profi...
Published: March, 2022

Abstract: The detection of low-abundance DNA N6-methyladenine (DNA-m6A) remains challenging, limiting our understanding of this novel base in eukaryotes. To ... Read more »

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Antibody

Phylogenomics and Comparative Genomics Highlight SpecificGenetic Fe...
Published: March, 2022

Abstract: The species in Polyporales are ecologically and economically relevant wood decayers used in traditional medicine, but their genomic traits are stil... Read more »

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Megaruptor

Complete Genome Sequence of Herpes Simplex Virus 2 StrainG.
Published: March, 2022

Abstract: Herpes simplex virus type (HSV-2) is a common causative agent of genital tract infections. Moreover, HSV-2 and HIV infection can mutually increase ... Read more »

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Megaruptor

Preterm birth buccal cell epigenetic biomarkers to facilitatepreven...
Published: March, 2022

Abstract: Preterm birth is the major cause of newborn and infant mortality affecting nearly one in every ten live births. The current study was designed to d... Read more »

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Antibody

Avian influenza viruses suppress innate immunity by inducingtrans-t...
Published: March, 2022

Abstract: Innate immunity plays critical antiviral roles. The highly virulent avian influenza viruses (AIVs) H5N1, H7N9, and H5N6 can better escape host inna... Read more »

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Antibody CRISPR

Corticosterone induces discrete epigenetic signatures in the dorsal...
Published: March, 2022

Abstract: The genomic effects of circulating glucocorticoids are particularly relevant in cortico-limbic structures, which express a high concentration of st... Read more »

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MagMeDIP kit

Regulation of paternal 5mC oxidation and H3K9me2 asymmetry byERK1/2...
Published: March, 2022

Abstract: BACKGROUND: Extracellular-signal-regulated kinase (ERK) direct cell fate determination during the early development. The intricate interaction betw... Read more »

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Antibody

GIF1 controls ear inflorescence architecture and floral development...
Published: March, 2022

Abstract: BACKGROUND: Inflorescence architecture and floral development in flowering plants are determined by genetic control of meristem identity, determina... Read more »

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Universal Plant ChIP-seq Kit

Pushing the limits of HiFi assemblies reveals centromere diversity ...
Published: February, 2022

Abstract: Although long-read sequencing can often enable chromosome-level reconstruction of genomes, it is still unclear how one can routinely obtain gapless... Read more »

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Megaruptor

Answer ALS: A Large-Scale Resource for Sporadic and Familial ALS C...
Published: February, 2022

Abstract: Answer ALS is a comprehensive multi-omics approach to ALS to ascertain, at a population level, the various clinical-molecular- biochemical subtypes... Read more »

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Chromatin Profiling (ChIP-seq) Services

Chromosomal rearrangements with stable repertoires of genes andtran...
Published: February, 2022

Abstract: Chromosomal rearrangements have been largely described among eukaryotes, and may have important consequences on evolution of species. High genome p... Read more »

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Megaruptor

Methionine Metabolism Controls the B-cell EBV Epigenome andViral La...
Published: February, 2022

Abstract: Epstein-Barr virus (EBV) subverts host epigenetic pathways to switch between viral latency programs, colonize the B-cell compartment and reactivate... Read more »

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MagMeDIP qPCR Kit

Antisense non-coding transcription represses the PHO5 model genevia...
Published: February, 2022

Abstract: Pervasive transcription of eukaryotic genomes generates non-coding transcripts with regulatory potential. We examined the effects of non-coding ant... Read more »

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Antibody CRISPR

Cell-type specific transcriptional networks in root xylem adjacent ...
Published: February, 2022

Abstract: Transport of water, ions and signals from roots to leaves via the xylem vessels is essential for plant life and needs to be tightly regulated. The ... Read more »

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Antibody

Genomic characterisation of three GES-producing Enterobacteralesiso...
Published: February, 2022

Abstract: OBJECTIVES: The aim of the study is to characterise the genomic features of three GES-producing Enterobacterales isolates from Czech hospitals. MET... Read more »

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Megaruptor

Screening of ETO2-GLIS2-induced Super Enhancers identifiestargetabl...
Published: February, 2022

Abstract: Super Enhancers (SEs) are clusters of regulatory elements associated with cell identity and disease. However, whether these elements are induced by... Read more »

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Antibody iDeal ChIP-seq Kit for Histones

ZBTB11 dysfunction: spectrum of brain abnormalities, biochemicalsig...
Published: February, 2022

Abstract: Bi-allelic pathogenic variants in ZBTB11 have been associated with Intellectual Developmental Disorder, autosomal recessive 69 (MRT69; OMIM 618383)... Read more »

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Bioruptor Chromatin Shearing

Transient regulation of focal adhesion via Tensin3 is required forn...
Published: February, 2022

Abstract: The differentiation of oligodendroglia from oligodendrocyte precursor cells (OPCs) to complex and extensive myelinating oligodendrocytes (OLs) is a... Read more »

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iDeal ChIP-seq Kit for Transcription Factors

Spatially resolved epigenomic profiling of single cells in complex ...
Published: February, 2022

Abstract: The recent development of spatial omics methods enables single-cell profiling of the transcriptome and the 3D genome organization in a spatially re... Read more »

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CUT&Tag

The genome sequence of a stonefly, Nemurella pictetii Klapalek, 1900
Published: February, 2022

Abstract: We present a genome assembly from an individual male Nemurella pictetii (Arthropoda; Insecta; Plecoptera; Nemouridae). The genome sequence is 257 m... Read more »

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Megaruptor

The genome sequence of the furry-claspered furrow bee, Lasioglossum...
Published: February, 2022

Abstract: We present a genome assembly from an individual male Lasioglossum lativentre (the furry-claspered furrow bee; Arthropoda; Insecta; Hymenoptera; Hal... Read more »

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Megaruptor

Epigenetic integrity of paternal imprints enhances the developmenta...
Published: February, 2022

Abstract: The use of two inhibitors of Mek1/2 and Gsk3β (2i) promotes the generation of mouse diploid and haploid embryonic stem cells (ESCs) from the inner ... Read more »

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Antibody

When left does not seem right: epigenetic and bioelectric differenc...
Published: February, 2022

Abstract: BACKGROUND: During embryogenesis lateral symmetry is broken, giving rise to Left/Right (L/R) breast tissues with distinct identity. L/R-sided breas... Read more »

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