Publications,References

Dual role of histone variant H3.3B in spermatogenesis: positiveregu...
Published: July, 2022

Abstract: The histone variant H3.3 is encoded by two distinct genes, H3f3a and H3f3b, exhibiting identical amino-acid sequence. H3.3 is required for spermato... Read more »

Tags
Microplex Library Preparation kit

Systematic comparison of CRISPR-based transcriptional activatorsunc...
Published: July, 2022

Abstract: Nuclease-inactivated CRISPR/Cas-based (dCas-based) systems have emerged as powerful technologies to synthetically reshape the human epigenome and g... Read more »

Tags
Antibody CRISPR

Equilibrated evolution of the mixed auto-/allopolyploidhaplotype-re...
Published: July, 2022

Abstract: Understanding genome evolution of polyploids requires dissection of their often highly similar subgenomes and haplotypes. Polyploid animal genome a... Read more »

Tags
Megaruptor

PARP1-SNAI2 transcription axis drives resistance to PARP inhibitor,...
Published: July, 2022

Abstract: The synthetic lethal association between BRCA deficiency and poly (ADP-ribose) polymerase (PARP) inhibition supports PARP inhibitor (PARPi) clinica... Read more »

Tags
iDeal ChIP-qPCR

Co-inhibition of ATM and ROCK synergistically improves cellprolifer...
Published: July, 2022

Abstract: The multifaceted nature of senescent cell cycle arrest necessitates the targeting of multiple factors arresting or promoting the cell cycle. We rep... Read more »

Tags
iDeal ChIP-seq Kit for Transcription Factors

Spatially resolved epigenome-transcriptome co-profiling of mammalia...
Published: June, 2022

Abstract: Emerging spatial technologies including spatial transcriptomics and spatial epigenomics are becoming powerful tools for profiling cellular states i... Read more »

Tags
Tagmentase CUT&Tag

A genome-wide screen reveals new regulators of the 2-cell-like cell...
Published: June, 2022

Abstract: In mammals, only the zygote and blastomeres of the early embryo are fully totipotent. This totipotency is mirrored in vitro by mouse "2-cell-like c... Read more »

Tags
Newly added

Epigenomic analysis reveals a dynamic and context-specific macropha...
Published: June, 2022

Abstract: BACKGROUND: Chromatin states and enhancers associate gene expression, cell identity and disease. Here, we systematically delineate the acute innate... Read more »

Tags
Antibody

Derailed peripheral circadian genes in polycystic ovary syndrome pa...
Published: June, 2022

Abstract: STUDY QUESTION: Do circadian genes exhibit an altered profile in peripheral blood mononuclear cells (PBMCs) of polycystic ovary syndrome (PCOS) pat... Read more »

Tags
iDeal ChIP-seq Kit for Transcription Factors

Nuclear receptor RORγ inverse agonists/antagonists display tissue- ...
Published: June, 2022

Abstract: The nuclear receptor RORγ is a major driver of autoimmune diseases and certain types of cancer due to its aberrant function in T helper 17 (T... Read more »

Tags
Antibody

Ultrasensitive Ribo-seq reveals translational landscapes during mam...
Published: June, 2022

Abstract: In mammals, translational control plays critical roles during oocyte-to-embryo transition (OET) when transcription ceases. However, the underlying ... Read more »

Tags
D-Plex small RNA-seq

Detection of ovarian cancer using plasma cell-free DNA methylomes.
Published: June, 2022

Abstract: BACKGROUND: Ovarian cancer (OC) is a highly lethal gynecologic cancer, and it is hard to diagnose at an early stage. Clinically, there are no ovari... Read more »

Tags
MagMeDIP kit

HISTONE DEACETYLASE 15 and MOS4-Associated Complex subunits3A/3B co...
Published: June, 2022

Abstract: Histone deacetylases (HDAs) play an important role in transcriptional regulation of multiple biological processes. In this study, we investigated t... Read more »

Tags
Antibody

TBX2 acts as a potent transcriptional silencer of tumour suppressor...
Published: June, 2022

Abstract: Chromosome 17q23 amplification occurs in 20\% of primary breast tumours and is associated with poor outcome. The TBX2 gene is located on 17q23 and ... Read more »

Tags
Microplex Library Preparation kit

Analysis of estrogen-regulated enhancer RNAs identifies a functiona...
Published: June, 2022

Abstract: To better understand the functions of non-coding enhancer RNAs (eRNAs), we annotated the estrogen-regulated eRNA transcriptome in estrogen receptor... Read more »

Tags
CRISPR

A genome-wide screen reveals new regulators of the 2-cell-like cell...
Published: June, 2022

Abstract: In mammals, only the zygote and blastomeres of the early embryo are fully totipotent. This totipotency is mirrored in vitro by mouse "2-cell-like c... Read more »

Tags
MagMeDIP kit IP-Star Compact

Long-read Oxford nanopore sequencing reveals a de novo case of comp...
Published: June, 2022

Abstract: BACKGROUND: Complex chromosomal rearrangements (CCRs) are associated with high reproductive risk, infertility, abnormalities in offspring, and recu... Read more »

Tags
Megaruptor

NSUN2-mediated RNA mC modification modulates uveal melanoma cellpro...
Published: June, 2022

Abstract: RNA 5-methylcytosine (mC) is a widespread post-transcriptional modification involved in diverse biological processes through controlling RNA metabo... Read more »

Tags
Antibody

Caffeine intake exerts dual genome-wide effects on hippocampal meta...
Published: June, 2022

Abstract: Caffeine is the most widely consumed psychoactive substance in the world. Strikingly, the molecular pathways engaged by its regular consumption rem... Read more »

Tags
Antibody Microplex Library Preparation kit CUT&Tag

EHF is a novel regulator of cellular redox metabolism and predictsp...
Published: June, 2022

Abstract: Head and Neck Squamous Cell Carcinoma (HNSCC) is a heterogeneous disease with relatively high morbidity and mortality rates. The lack of effective ... Read more »

Tags
Chromatin Shearing Antibody

Accumulation of endosymbiont genomes in an insect autosome followed...
Published: May, 2022

Abstract: Eukaryotic genomes can acquire bacterial DNA via lateral gene transfer (LGT). A prominent source of LGT is Wolbachia, a widespread endosymbiont of ... Read more »

Tags
Megaruptor

DNA Hypermethylation and a Specific Methylation Spectrum on theX Ch...
Published: May, 2022

Abstract: The molecular genetic mechanism of Turner syndrome (TS) still leaves much to be discovered. Methods: TS (45X0) patients and age-matched controls (4... Read more »

Tags
Megaruptor

Development of a quantitative methylation-specific droplet digital ...
Published: May, 2022

Abstract: OBJECTIVE: The detection and monitoring of DNA methylation status in circulating tumor cell DNA (ctDNA) provides critical insights into cancer diag... Read more »

Tags
Premium Bisulfite Kit

DNA methylation may affect beef tenderness through signal transduct...
Published: May, 2022

Abstract: BACKGROUND: Beef tenderness is a complex trait of economic importance for the beef industry. Understanding the epigenetic mechanisms underlying thi... Read more »

Tags
Premium RRBS Kit DNA Methylation Profiling (RRBS Service)

Cell-wall damage activates DOF transcription factors to promote wou...
Published: May, 2022

Abstract: Wound healing is a fundamental property of plants and animals that requires recognition of cellular damage to initiate regeneration. In plants, wou... Read more »

Tags
IPure kit

TRF2 cooperates with CTCF for controlling the oncomiR-193b-3p incol...
Published: May, 2022

Abstract: The Telomeric Repeat binding Factor 2 (TRF2), a key protein involved in telomere integrity, is over-expressed in several human cancers and promotes... Read more »

Tags
Antibody

GATA6 is predicted to regulate DNA methylation in an in vitro model...
Published: May, 2022

Abstract: Hepatocytes are the dominant cell type in the human liver, with functions in metabolism, detoxification, and producing secreted proteins. Although ... Read more »

Tags
IP-Star Compact iDeal ChIP-seq Kit for Transcription Factors ChIPmentation

Developmental mRNA mC landscape and regulatory innovations of massi...
Published: May, 2022

Abstract: mC is one of the longest-known RNA modifications, however, its developmental dynamics, functions, and evolution in mRNAs remain largely unknown. He... Read more »

Tags
Antibody

Heat stress during grain filling regulates seed germination through...
Published: May, 2022

Abstract: KEY MESSAGE: Alterations in DNA methylation levels of ROS, GA and ABA related gene promoters cause transcriptional changes upon imbibition to induc... Read more »

Tags
MagMeDIP kit

AP4 suppresses DNA damage, chromosomal instability and senescence v...
Published: May, 2022

Abstract: Background AP4 (TFAP4) encodes a basic helix-loop-helix leucine zipper (bHLH-LZ) transcription factor and is a direct target gene of the oncogenic ... Read more »

Tags
iDeal ChIP-qPCR

Publications

活动